Spatial Positioning of RET and H4 Following Radiation Exposure Leads to Tumor Development by Yuri E. Nikiforov

“…Exposure to ionizing radiation is a well-known risk factor for a number of human cancers, including leukemia, thyroid cancer, soft tissue sarcomas, and many others. Although it has been known for a long time that radiation exposure to the cell results in extensive DNA damage, including double strand DNA breaks, the exact mechanisms of radiation-induced carcinogenesis remain unknown. …”
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David Slays Goliath: Exceptional Efficacy of Oral Vinorelbine in Conquering Metastatic Finger Angiosarcoma by Te-Lin Hsu, San-Chi Chen

“…Angiosarcoma (AS) is a rare and aggressive disease originating from blood or lymphatic vessel endothelium, representing <1% of soft-tissue sarcomas. The prognosis is generally poor, with a 5-year survival rate of only 30%–50%. …”
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NTRK-rearranged spindle cell tumor with SPECC1L-NTRK3 fusion in the thoracic spine: a case report by Mi Zhou, Huaiyuan Xu, Jianxiong Niu, Qibing Yang, Anqi Wang, Hao Wu, Xiangqin Wang, Meng Yang, Jinxin Hu, Qinglian Tang, Jin Wang

“…For bone-derived NTRK-rearranged spindle cell sarcomas, entrectinib shows promising therapeutic efficacy and should be considered a preferred treatment option.…”
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Primary Angiosarcoma of the Spleen: An Oncological Enigma by Myoteri Despoina, Dellaportas Dionysios, Ayiomamitis Georgios, Strigklis Konstantinos, Kouroumpas Efstratios, Zizi-Sermpetzoglou Adamantia

“…Imaging modalities cannot differentiate the lesion from other vascular splenic neoplasms and the correct diagnosis is mainly set after histopathological examination of the resected spleen. As with other sarcomas, surgery is the only curative approach, while chemo- and radiotherapy have poor results. …”
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Primitive Neuroectodermal Tumor of the Liver: A Case Report by Eduardo Cambruzzi, Enilde Eloena Guerra, Hamilton Cardoso Hilgert, Herbert Jorge Schmitz, Vinícius Lopes Silva, Daniel Marini Milani, Ricardo Pedrini Cruz, Raul Pruinelli

“…Primary liver sarcomas represent a rare group of neoplasias, with angiosarcoma being the most common histological type. …”
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Malignant Fibrous Histiocytoma of the Breast in Young Male Patient: A Case Report and a Review of the Literature by Esengul Kocak Uzel, Metin Figen, Tuba Tulin Bek, Kubilay Inanc, Senem Onder, Hazim orhan Kizilkaya

“…Breast cancer is rarely seen in males, accounts for approximately 1% of all breast cancer, and the breast sarcomas constitute less than 1% of breast tumors in both sexes. …”
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Epithelioid Angiosarcoma Arising from a Huge Leiomyoma: A Case Report and a Literature Review by Takeya Hara, Ai Miyoshi, Yuji Kamei, Nao Wakui, Akiko Fujishiro, Serika Kanao, Hirokazu Naoi, Hirofumi Otsuka, Takeshi Yokoi

“…Uterine mesenchymal tumors other than leiomyosarcoma, carcinosarcoma, and endometrial stromal sarcomas are extremely uncommon. We describe a case of epithelioid angiosarcoma of the uterus and review previous literature on such rare tumors. …”
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Hemangiopericytoma of the Breast: A Case Report and a Review of the Literature by Georgios Koukourakis, Evagelos Filopoulos, Kasiani Kapatou, Georgios Zacharias

“…Introduction. Sarcomas of the breast are rare and hemangiopericytoma (HPC) of the breast is even rarer. …”
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A Review on the Antimutagenic and Anticancer Effects of Cysteamine by Chun-Man Lee

“…The efficacy of cysteamine has been shown in vitro and in vivo for the treatment of different types of cancer, such as gastrointestinal cancer, pancreatic cancer, sarcomas, hepatocellular carcinoma, and melanoma, leading to the significant reduction of lesions and/or the increase of survival time. …”
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Advanced Mesodermal (Müllerian) Adenosarcoma of the Ovary: Metastases to the Lungs, Mouth, and Brain by A. Daskalaki, S. Xenaki, E. Athanasakis, E. Chrysos, G. Chalkiadakis

“…Despite the fact that sarcomas have a long-term metastatic potential, to our knowledge this is the first case of Müllerian adenosarcoma presenting with such extraperitoneal metastases.…”
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Liposarcoma of the Nasopharynx: Diagnosis and Management of a Rare Diagnostic Entity by George X. Papacharalampous, Dimitrios Kikidis, Alexios Vasileiou, Aggeliki Bousiotou, Aristeidis Chrysovergis

“…Liposarcoma is one of the most frequently occurring soft tissue sarcomas in adulthood. The majority of liposarcomas arise in the lower extremities and retroperitoneum, while the incidence of this tumor in the head and neck region is reported to be extremely low, comprising 1.8%–6.2% of all cases. …”
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The Natural History of Pancreatic Cancer in Manitoba: A Population Based Study by Jack Martin, Brian H Weinerman

“…Two hundred and fourteen exocrine cases were identified, and known islet cell tumours, lymphomas and sarcomas were excluded. The variables analyzed were age, sex, surgical or radiological stage of disease, pathological differentiation, means of diagnosis and treatment. …”
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Clinical Trials of Immunogene Therapy for Spontaneous Tumors in Companion Animals by Gerardo Claudio Glikin, Liliana María Elena Finocchiaro

“…A variety of tumors such as canine melanoma, soft tissue sarcomas, osteosarcoma and lymphoma, feline fibrosarcoma, and equine melanoma were subjected to different treatment approaches. …”
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A Rare Malignant Peripheral Nerve Sheath Tumor of the Maxilla Mimicking a Periapical Lesion by José Alcides Arruda, Pamella Álvares, Luciano Silva, Alexandrino Pereira dos Santos Neto, Cleomar Donizeth Rodrigues, Antônio Caubi, Marcia Silveira, Sandra Sayão, Ana Paula Sobral

“…About 50% of this tumor occurs in patients with neurofibromatosis type I and comprises approximately 10% of all soft tissue sarcomas of head and neck region. Intraosseous malignant peripheral nerve sheath tumor of the maxilla is rare. …”
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Leiomiossarcoma de Vagina em Paciente Gestante: Relato de Caso by Amanda de Queiroz Piffer, Ana Victoria Carvalho Domingues, Letícia Iamada Porto, Maria Amália Barbosa Duarte de Oliveira, Giuliano Tavares Tosello

“… Introdução: As lesões malignas primárias da vagina são atípicas, e sarcomas vaginais ainda mais incomuns. Leiomiossarcomas retratam menos de 2% das neoplasias malignas ginecológicas, e apenas 10% destes ocorrem fora do útero. …”
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Rotationplasty with Vascular Reconstruction for Prosthetic Knee Joint Infection by Masahide Fujiki, Shimpei Miyamoto, Fumihiko Nakatani, Akira Kawai, Minoru Sakuraba

“…Rotationplasty is used most often as a function-preserving salvage procedure after resection of sarcomas of the lower extremity; however, it is also used after infection of prosthetic knee joints. …”
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Malignant Granular Cell Tumor of the Back: A Case Report and Review of the Literature by Laura Stone McGuire, Danny Yakoub, Mecker G. Möller, Andrew Rosenberg, Alan Livingstone

“…Following surgery, patient was started on Pazopanib 800 mg/day based on phase III randomized trial data in the treatment of soft tissue sarcomas showing this as a potential novel therapy for malignant granular cell tumors.…”
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Paravertebral Well-Differentiated Liposarcoma with Low-Grade Osteosarcomatous Component: Case Report with 11-Year Follow-Up, Radiological, Pathological, and Genetic Data, and Liter... by Nicolas Macagno, Stéphane Fuentes, Gonzague de Pinieux, André Maues de Paula, Sébastien Salas, Jean-Camille Mattéi, Charlotte Dupuis, Romain Appay, Alain Aurias, Henry Dufour, Dominique Figarella-Branger, Corinne Bouvier

“…Despite being one of the most frequent soft-tissue sarcomas, well-differentiated liposarcoma has never been reported near the spine. …”
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Leiomyosarcoma of the Right Gonadal Vein: Review of the Approach and Prognostic in a Rare Case by Noa de la Fuente, Manuel Rodríguez Blanco, Gemma Cerdán, Antonio Moral, Vicenç Artigas

“…Venous leiomyosarcoma is a mesenchymal tumour that represents 5-7% of soft tissue sarcomas. It originates in the smooth muscle cells of the vessel wall and is frequently located in the inferior vena cava. …”
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Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma with Intramuscular Lipoma-Like Component of the Thigh by Chairat Burusapat, Nuttadon Wongprakob, Nutthapong Wanichjaroen, Chatchai Pruksapong, Kantang Satayasoontorn

“…ALT most frequently occurs in deep soft tissue of proximal extremities (thigh and buttock) and usually presents as a deep-seated, painless mass that can slowly attain a very large size, which is one of the most common sarcomas of extremity. In the patients who presented with deep-seated tumor, distinction between intramuscular lipoma and well-differentiated liposarcoma is important due to the differences in treatment and prognosis. …”
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