Post Irradiation Spindle Cell Carcinoma of Tonsillar Pillar by Prateek Kinra, V. Srinivas, Kavita Sinha, Vibha Dutta

“…Postradiation spindle cell carcinoma is an uncommon disease manifesting as sarcoma in a previously irradiated field, usually with a latent period of 5 years or more. …”
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Beyond Immunuhistochemistry: Molecular Insights Into Round Cell Soft Tissue Tumors by Prashanth Kumar Madoori, Sujatha Tejavat

“…Key subtypes, including Ewing sarcoma, CIC- and BCOR-rearranged sarcomas, alveolar rhabdomyosarcoma, desmoplastic small round cell tumor, and extraskeletal myxoid chondrosarcoma, are discussed with emphasis on their molecular signatures and clinical significance. …”
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An unexpected and tumultuous diagnosis of a left atrial mass by Catarina Amaral Marques, Carlos Xavier Resende, João Rebelo, Paulo Pinho, Mariana Vasconcelos, Rui André Rodrigues

“…After cardiac magnetic resonance and the exclusion of extra-cardiac lesions, sarcoma emerged as the main diagnostic hypothesis. …”
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Clinical Presentation of Preeclampsia and the Diagnostic Value of Proteins and Their Methylation Products as Biomarkers in Pregnant Women with Preeclampsia and Their Newborns by Maria Portelli, Byron Baron

“…The clinical presentation of PE and data gathered for the biochemical markers placental growth factor (PlGF), soluble Feline McDonough Sarcoma- (fms-) like tyrosine kinase-1 (sFlt-1), asymmetric dimethylarginine (ADMA), and methyl-lysine is being reviewed with the aim of providing both a clinical and biochemical understanding of how these biomarkers might assist in the diagnosis of PE or indicate its severity.…”
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The utilization of microbial cell-free DNA next-generation sequencing for the detection of human herpesvirus-8 in a quaternary care center by Rebecca Berger, Jennifer Jacobe, Fernando H. Centeno, Todd Lasco, Mayar Al Mohajer

“…While violaceous skin lesions characterize cutaneous Kaposi sarcoma, extracutaneous HHV8 is challenging to diagnose due to nonspecific symptoms. …”
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Atypical Cutaneous Fibrous Histiocytoma: An Unusual and Misleading Variant of Fibrous Histiocytoma by Soumaya Ben Abdelkrim, Colondane Belajouza, Wafa Jomaa, Nadia Beizig, Zeineb Ben Said, Moncef Mokni, Rafia Nouira, Badreddine Sriha

“…Atypical fibrous histiocytoma is a distinctive variant of cutaneous fibrous histiocytoma, which is often mistaken histologically for sarcoma and which have a tendency to recur locally and a capacity to metastasize, although very rarely. …”
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Evading Capture by Residual Disease Monitoring: Extramedullary Manifestation of JAK2 V617F-Positive Primary Myelofibrosis After Allogeneic Stem Cell Transplantation by Stephen E. Langabeer, James Nolan, Karl Haslam, Lindsey Clarke, Richard Flavin, Eibhlin Conneally

“…Prospective residual disease monitoring of the peripheral blood failed to detect an extramedullary manifestation of the disease, a periorbital myeloid sarcoma, arising nearly three years after transplant. …”
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KSHV hijacks the antiviral kinase IKKε to initiate lytic replication. by Xiaoqian Wang, Zhenshan Liu, Xue Xu, Xin Wang, Zizhen Ming, Chengrong Liu, Hang Gao, Tingting Li, Qiming Liang

“…However, through an inhibitor screen targeting cellular kinases, we found that IKKε plays a crucial role in the lytic replication of Kaposi's sarcoma-associated herpesvirus (KSHV). Mechanistically, during KSHV lytic replication, IKKε undergoes significant SUMOylation at both Lys321 and Lys549 by the viral SUMO E3 ligase ORF45. …”
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Cardiac Dedifferentiated Liposarcoma Requiring a Mitral Valve Replacement Complicated by Severe Paravalvular Leak: A Rare Case Report with Literature Review by Anju Adhikari, Adam Hafeez, Alexandra Halalau

“…Cardiac sarcomas have a high infiltrative and metastatic potential and are often associated with poor prognosis. …”
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High-Grade Leiomyosarcoma Arising in a Previously Replanted Limb by Tiffany J. Pan, Liron Pantanowitz, Kurt R. Weiss

“…Sarcoma development has been associated with genetics, irradiation, viral infections, and immunodeficiency. …”
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Rectus Abdominis Muscle Malignant Fibrous Histiocytoma Causing a Large Abdominal Wall Defect: Reconstruction with Biological Mesh by Evangelos Falidas, Stavros Gourgiotis, Christina Goudeli, Stavros Mathioulakis, Konstantinos Vlachos, Constantinos Villias

“…Malignant fibrous histiocytoma (MFH) is a common soft tissue sarcoma usually involving limbs and retroperitoneum. …”
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Vulvar Malignancy in Neurofibromatosis Syndrome by Angela Musella, Innocenza Palaia, Lavinia Domenici, Assunta Casorelli, Angela Martoccia, Pierluigi Benedetti Panici

“…The purpose of this case is to underline the possibility of association between NF1 and genital tract sarcoma and to suggest an accurate evaluation of rapid growth vulvar mass in this setting.…”
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HHV8-Negative Primary Effusion Lymphoma of B-Cell Lineage: Two Cases and a Comprehensive Review of the Literature by Neeraj Saini, Ephraim P. Hochberg, Erica A. Linden, Smita Jha, Heinz K. Grohs, Aliyah R. Sohani

“…The neoplastic lymphoid cells are frequently infected with human herpes virus 8 (HHV8), also known as Kaposi sarcoma herpes virus (KSHV). We describe two HIV-negative patients who presented with primary effusion lymphoma of B-cell lineage involving the pleural cavity, but whose tumor cells lacked infection by HHV8. …”
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Lung Cancer Prediction Using Neural Network Ensemble with Histogram of Oriented Gradient Genomic Features by Emmanuel Adetiba, Oludayo O. Olugbara

“…These machine learning classifiers were trained to predict lung cancer using samples of patient nucleotides with mutations in the epidermal growth factor receptor, Kirsten rat sarcoma viral oncogene, and tumor suppressor p53 genomes collected as biomarkers from the IGDB.NSCLC corpus. …”
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Garre’s Osteomyelitis of the Mandible Caused by Infected Tooth by Hayati Murat Akgül, Fatma Çağlayan, Sevcihan Günen Yılmaz, Gözde Derindağ

“…Therefore, it should be distinguished from other pathologies that cause new bone formation, such as Ewing’s sarcoma, Caffey disease, and fibrous dysplasia.…”
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Treatment Choices for Tenosynovial Giant Cell Tumor: Surgery or Observation? by Hairong XU, Jing CHEN, Xiaohui NIU

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Desmoplastic Small Round Cell Tumor, a “Floating Island” Pattern in Pleural Fluid Cytology: A Case Report and Review of the Literature by Hui Zhu, Emily Marie McMeekin, Charles D. Sturgis

“…Desmoplastic small round cell tumor (DSRCT) is a rare aggressive sarcoma with characteristic clinical and pathologic features. …”
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A Case of Giant Bladder Carcinosarcoma without Submucosal Invasion by Masayoshi Zaitsu, Mariko Yamanoi, Koji Mikami, Akiko Tonooka, Toshimasa Uekusa, Takumi Takeuchi

“…The specimens taken at the second-look TUR-Bt revealed that carcinoma in situ (urothelial cancer) but not sarcoma existed at the mucosa surrounding the previous tumor site. 80 mg of BCG instillation intravesically every week for six weeks was successfully administered to the patient. …”
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About a Large Botryoid Rhabdomyosarcoma in a Little Girl: Management Difficulties and Literature Review by Dehi Boston Mian, Vedi Andre Serges Loue, Sylvanus Koui

“…Rhabdomyosarcoma (RMS) is a rare high-grade malignant tumor and the most common soft-tissue sarcoma, which occurs in young girl over 5 years old. …”
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Primary Clear Cell Chondrosarcoma of the Spine: A Case Report of a Rare Entity and a Review of the Literature by Nikolaos A. Paidakakos, Aristides Rovlias, Evaggelos Rokas, Spyridon Theodoropoulos, Patroklos Katafygiotis

“…Chondrosarcoma is the third most common primary malignant bone tumor after osteosarcoma and Ewing’s sarcoma. Clear cell chondrosarcoma is a rare subtype variant of chondrosarcoma, most commonly encountered in the proximal part of the femur or humerus. …”
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