National Consensus for the Management of Acute Gastroenteritis in Jordanian Children: Consensus Recommendations Endorsed by the Jordanian Paediatric Society by Mohammed Rawashdeh, Basim Al-Zoubi, Maha Barbar Aliwat, Salma Burayzat, Esam Alhindawi, Ali Attia Al-Matti, Eyad Altamimi

“…The prevention of diarrhoeal diseases should focus on the improvement of nutrition, hygiene, and sanitation, the introduction of routine vaccination against rotavirus, and the adoption of a standardised approach for AGE management (oral rehydration solution (ORS) use±adjunct therapies, continued feeding, and avoiding routine antibiotic use). …”
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Influence of Zinc Supplementation in Acute Diarrhea Differs by the Isolated Organism by Archana B. Patel, Michael J. Dibley, Manju Mamtani, Neetu Badhoniya, Hemant Kulkarni

“…Using prespecified subgroup analyses, multidimensionality reduction analyses, tests of heterogeneity, and stepwise logistic regression for tests of interactions, we found that the influence of zinc on the risk of diarrhea for more than 3 days depended on the isolated organism—beneficial in Klebsiella, neutral in Esherichia coli and parasitic infections, and detrimental in rotavirus coinfections. Although we found similar results for the outcome of high stool volume, the results did not reach statistical significance. …”
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Homeostatic antiviral protection of the neonatal gut epithelium by interferon lambda by Bryan Ramirez Reyes, Shelby Madden, Kimberly A. Meyer, Brenden Bartsch, Austin P. Wright, David A. Constant, Timothy J. Nice

“…Here, we find that neonatal IECs express antiviral genes at homeostasis that depend on interferon lambda (IFN-λ) and are required for early control of mouse rotavirus (mRV) infection. Neonatal homeostatic IFN-λ responses are independent of microbiota and pervasively distributed among IECs, distinguishing them from the homeostatic responses of adult mice. …”
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Emerging Norovirus GII.12 infection in 2010 in Northern Taiwan by Chi-Neu Tsai, Yu-Chung Chang, Hsun-Ching Chao, Yi-Hsiang Hsu, Yuan-Hung Wang, Shih-Yen Chen

“…Norovirus (NoV) has been an emerging pathogen of enteric infections in the post-rotavirus vaccine era. GII.4 have played a major role in NoV infections while other genotypes were reported in sporadic outbreaks. …”
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The relationship between hemogram parameters and mortality in neonatal calves with diarrhea by Merve Ider, Amir Naseri, Alper Erturk

“…In addition, on the basis of the stool quick test and etiological agent, it was divided into 3 subgroups: bacterial (E. coli), viral (rotavirus and coronavirus), and parasitic (Cryptosporidium parvum). …”
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Genome Characterization of Mammalian Orthoreovirus and Porcine Epidemic Diarrhea Virus Isolated from the Same Fattening Pig by Xiaoxuan Li, Jiakai Zhao, Jingjie Li, Yangzong Xiri, Zhixiang Liu, Qin Zhao, Yani Sun

“…Fecal samples were collected from diseased pigs and tested by PCR for the presence of mammalian orthoreovirus (MRV), porcine epidemic diarrhea virus (PEDV), porcine deltacoronavirus (PDCoV), porcine rotavirus A (PoRVA), transmissible gastroenteritis virus (TGEV), porcine kobuvirus (PKV), and pseudorabies virus (PRV). …”
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Vitamin D3/VDR alleviates double-stranded RNA virus -induced biliary epithelial cell damage by inhibiting autophagy by Na Liu, Pu Zhao, Ping Cao, JunPeng Hui, YongKang Pan, Jiwen Cheng

“…A BA mouse model was established through the intraperitoneal sequential injection of rhesus rotavirus (RRV). The role of VDR in the pathogenesis and progression of BA was examined using in vitro and in vivo models. …”
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Prevalence of Diarrhea Disease and Associated Factors Among Children Under 5 Years in Geshiyaro Project Implementation Sites in Ethiopia: A Cross‐Sectional Study by Zinabu Assefa Alemu, Aderajew Mekonnen Girmay, Kirubel Tesfaye Teklu, Ermias Alemayehu Adugna, Melaku Gizaw Serte, Tsigereda Assefa Alemayehu, Badasa Wagari Likasa, Benjamin Collyer, Zelalem Mehari, Mihretab Salasibew, Getachew Tollera, Masresha Tessema

“…The following factors were significantly associated (p < 0.05) with the occurrence of childhood diarrhea: sex of the child (AOR: 1.6; 95% CI, 1.17–2.19), child age in a month (AOR: 0.5; 95% CI, 0.26–0.94), drinking water service (AOR: 2.6; 95% CI, 1.33–5.25), knowledge on diarrhea prevention (AOR: 1.4; 95% CI, 1.05–1.98), open defecation practice (AOR: 1.9; 95% CI, 1.33–2.74), and rotavirus vaccination (AOR: 1.8; 95% CI, 1.20–2.56). …”
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Transcriptional analysis of murine biliary atresia identifies macrophage heterogeneity and subset-specific macrophage functions by Kyle D. Gromer, Shang-Yang Chen, Gaurav Gadhvi, Liang Feng, Colin Shearn, Swati Antala, Swati Antala, Joshua B. Wechsler, Carla M. Cuda, Cara L. Mack, Ronald J. Sokol, William J. Janssen, Richard M. Green, Harris Perlman, Deborah R. Winter, Sarah A. Taylor, Sarah A. Taylor

“…We aimed to distinguish the transcriptional profiles and roles of defined macrophage subset(s) in murine BA.MethodsWe used multiparameter flow cytometry and RNA-sequencing analysis to profile recruited CD11bhiCD64+ hepatic macrophages by cell surface expression of MHCII and Ly6c in the Rhesus rotavirus (RRV)-induced murine model of BA versus saline controls. …”
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Derivation and validation of a clinical predictive model for longer duration diarrhea among pediatric patients in Kenya using machine learning algorithms by Billy Ogwel, Vincent H. Mzazi, Alex O. Awuor, Caleb Okonji, Raphael O. Anyango, Caren Oreso, John B. Ochieng, Stephen Munga, Dilruba Nasrin, Kirkby D. Tickell, Patricia B. Pavlinac, Karen L. Kotloff, Richard Omore

“…The following variables were associated with LDD in decreasing order: pre-enrolment diarrhea days (55.1%), modified Vesikari score(18.2%), age group (10.7%), vomit days (8.8%), respiratory rate (6.5%), vomiting (6.4%), vomit frequency (6.2%), rotavirus vaccination (6.1%), skin pinch (2.4%) and stool frequency (2.4%). …”
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Role of Antidiarrhoeal Drugs as Adjunctive Therapies for Acute Diarrhoea in Children by Christophe Faure

“…Principal pathogens include Escherichia coli, rotaviruses, and noroviruses. 90% of diarrhoeal deaths are attributable to inadequate sanitation. …”
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Astrovirus infection in animals (literature review) by V. A. Mischenko, A. V. Mischenko, Т. B. Nikeshina, О. N. Petrova

“…The most common viral gastroenteritis agents in calves are rotaviruses, coronaviruses and pestiviruses, and, along with these, astroviruses are increasingly being detected. …”
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Bovine nebovirus infection (review) by V. A. Mischenko, A. V. Mischenko, T. B. Nikeshina, Yu. V. Brovko, A. I. Kushlubaeva

“…In most cases viruses serve as triggers for gastrointestinal pathology development and bacteria play the secondary role. For a long time, rotaviruses, coronaviruses and pestiviruses have been believed to play the main role in etiology of massive neonatal calf diarrhea. …”
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