Microfluidic Synthesis of miR-200c-3p Lipid Nanoparticles: Targeting ZEB2 to Alleviate Chondrocyte Damage in Osteoarthritis by Zheng D, Chen T, Yang K, Yin G, Chen Y, Gui J, Xu C, Lv S

“…Collagen II expression rose following transfection of si-ZEB2, whereas the expression levels of inflammatory factors, apoptosis-related proteins, MMP3, MMP13, and ADAMTS-4 decreased. …”
Get full text

Seroprevalence of brucellosis in camels and humans in the Al-Qassim region of Saudi Arabia and its implications for public health by Abdulaziz M. Almuzaini, Abdullah S. M. Aljohani, Ahmed I. Alajaji, Ayman Elbehiry, Adil Abalkhail, Abdulrahman Almujaidel, Sahar N. Aljarallah, Hazem R. Sherif, Eman Marzouk, Abdelmaged A. Draz

“…., age, size, and location), and conducting molecular characterization of Brucella spp. associated with abortion in camels. The Rose Bengal Test (RBT), Antigen Rapid Brucella Antibody Test (ARBT), indirect enzyme-linked immunosorbent assay (I-ELISA), and complement fixation test (CFT) were used to detect brucellosis in both camels and humans. …”
Get full text

SARS-CoV-2 transmission dynamics in Mozambique and Zimbabwe during the first 3 years of the pandemic by Roselyn F. Kaondera-Shava, Marta Galanti, Matteo Perini, Jiyeon Suh, Shannon M. Farley, Sergio Chicumbe, Ilesh Jani, Annette Cassy, Ivalda Macicame, Naisa Manafe, Wafaa El-Sadr, Jeffrey Shaman

“…Total infection burdens (reported and unreported) during the first 3 years of the pandemic were reconstructed using a model-inference approach. Transmission rates rose with each successive wave, which aligns with observations in other continents. …”
Get full text

Neutrophil Gelatinase-Associated Lipocalin in Kidney Transplantation Is an Early Marker of Graft Dysfunction and Is Associated with One-Year Renal Function by Isabel Fonseca, José Carlos Oliveira, Manuela Almeida, Madalena Cruz, Anabela Malho, La Salete Martins, Leonídio Dias, Sofia Pedroso, Josefina Santos, Luísa Lobato, António Castro Henriques, Denisa Mendonça

“…Shortly after KTx (3–6 h), uNGAL values were higher in DGF recipients (on average +242 ng/mL, considering mean dialysis time of 4.1 years) and rose further in following days, contrasting with prompt function recipients. …”
Get full text

Normal butanol fraction of Polygonum hydropiper L. flavonoids reduces inflammation caused by PCV2 infections in cell and mouse models by Yu-heng Wei, Shu-mian Zhou, Shu-mian Zhou, Shu-mian Zhou, Wen Zhao, Qi Chen, Qiu-hua Wang, Qiu-hua Wang, Mei-ling Yu, Ying-yi Wei, Ting-jun Hu, Ting-jun Hu, Ting-jun Hu

“…Additionally, mRNA and protein levels for TNF-α, IL-8, IL-10, IL-6, and iNOS rose significantly in lung tissues (p < 0.01) but decreased with FNB treatment (p < 0.05 or p < 0.01).DiscussionThese findings suggest that FNB reduces inflammatory factor production and modulates the inflammatory response triggered by PCV2 infection, potentially enhancing host resistance against it.…”
Get full text

Phase Transitions and Structural Evolution of Manganese Ores During High-Temperature Treatment by Ruslan Z. Safarov, Yerlan A. Baikenov, Assemgul K. Zhandildenova, Eldar E. Kopishev, Ruslan M. Kamatov, Jumat B. Kargin, H. Sanchez Cornejo, Crispin H. W. Barnes, Luis De Los Santos Valladares

“…In the Bogach ore samples, manganese content increased from 60.77% to 65.7% as the sintering temperature rose to 1100 °C, while the hausmannite phase (Mn₃O₄) emerged as the dominant phase, comprising 95.77% of the crystalline component at 1200 °C. …”
Get full text

Data-driven insights into pre-slaughter mortality: Machine learning for predicting high dead on arrival in meat-type ducks by Chalita Jainonthee, Phutsadee Sanwisate, Panneepa Sivapirunthep, Chanporn Chaosap, Raktham Mektrirat, Sudarat Chadsuthi, Veerasak Punyapornwithaya

“…Additionally, several data-sampling techniques, including oversampling, undersampling, Random Over-Sampling Examples (ROSE), and Synthetic Minority Over-sampling Technique (SMOTE), were utilized to address the issue of imbalanced data. …”
Get full text

Liver Metastases in Pancreatic Acinar Cell Carcinoma Treated with Selective Internal Radiation Therapy with Y-90 Resin Microspheres by Felipe Nasser, Joaquim Maurício Motta Leal Filho, Breno Boueri Affonso, Francisco Leonardo Galastri, Rafael Noronha Cavalcante, Diego Lima Nava Martins, Vanderlei Segatelli, Lilian Yuri Itaya Yamaga, Rene Claudio Gansl, Bernardino Tranchesi Junior, Antônio Luiz de Vasconcellos Macedo

“…Lipase concentration was 8407 U/L at baseline, rose to 12,705 U/L after pancreatectomy, and declined to 344 U/L after SIRT. …”
Get full text

Application of quality control circle activities for implementation of Traditional Chinese Medicine nursing for ICU patients (提高ICU患者中医护理操作实施率的品管圈实践)... by ZHANG Lijuan (张丽娟), CAI Shujun (蔡书君), PAN Wenting (潘文婷), CHENG Jingjing (成晶晶)

“…Results The implementation rate of TCM nursing rose form 56. 31% before QCC activities to 86. 63% after QCC activities, with a significant difference (P＜0. 01). …”
Get full text

Research on equity analysis and forecasting of nursing human resource allocation in Jiangxi Province, China by Yunyu Du, Zhiqin Xie, Zhen Yang, Wanyin Xiong, Li Zhou, Min Zhang, Suhua Zeng, Min Wang

“…Registered nurses per 1,000 population rose by 2.21, while nurses per square kilometer increased by 0.66. …”
Get full text

Factors associated with thermal injury of abdominal skin in focused ultrasound ablation of uterine fibroids by Tang Chendian, Huang Guohua, Zhibiao Wang, Liu Fang, Shuang Luo, Xiaofang Liu, Qiuling Shi

“…And as the level of thermal injury rose, the ratio gradually increased, however, without statistical difference.Conclusions Based on our limited results, the following conclusion was made. (1) Abdominal scars, abdominal wall thickness, fundus fibroids, UFs with T2WI hyperintense/mixed signals, AP and TT were independent risk factor. (2) Neither too thick nor too thin abdominal walls would be recommended, as both might increase the risk of skin injury. (3) Noticeably, the risk of skin injury might increase considerably when the ST was longer and the sonication area was more fixed.…”
Get full text

Nisin A-producing Lactococcus cremoris formulations for pre- and post-milking teat disinfection modulate the bovine milk microbiota by Alessandra Gazzola, Camilla Ceccarani, Bianca Castiglioni, Filippo Biscarini, Stefano Morandi, Tiziana Silvetti, Renata Piccinini, Milena Brasca, Paola Cremonesi

“…Streptococcaceae significantly decreased in CTR (p = 0.013) and rose in TR (p = 0.001). Several differences were observed between the two groups during the experimental period. …”
Get full text

Oridonin: A natural terpenoid having the potential to modulate apoptosis and survival signaling in cancer by Abhishek Chauhan, Hemant Joshi, Divya Kandari, Diwakar Aggarwal, Ritu Chauhan, Hardeep Singh Tuli, Arpit Mehrotra, Abhilasha Sood, Ujjawal Sharma, Darin Mansor Mathkor, Shafiul Haque, Naveen Chandra Joshi, Laurent Dufossé

Get full text

Beef cattle performance and hair cortisol accumulation in silvopastoral and pastoral systems: a 2-year assessment by A. Ripamonti, G. Foggi, A. Mantino, L. Turini, J. Goracci, A. Silvi, M. Finocchi, M. Mele

“…In 2022, cortisol levels rose further to 46.56 pg/mg in PAs and 42.94 pg/mg in SPs. …”
Get full text

Application of Minimally Invasive Oral Swab Samples for qPCR-Based Sexing in Neognathae Birds by Maria-Carmen Turcu, Anamaria Ioana Paștiu, Lucia-Victoria Bel, Anca-Alexandra Doboși, Dana Liana Pusta

“…A total of 34 samples were included in this study from the following 17 bird species: domestic pigeon (<i>Columba livia domestica</i>), domestic chicken (<i>Gallus gallus domesticus</i>), domestic goose (<i>Anser anser f domesticus</i>), domestic duck (<i>Anas platyrhynchos domesticus</i>), Mute swan (<i>Cygnus olor</i>), Budgerigar (<i>Melopsittacus undulatus</i>), Lovebird (<i>Agapornis roseicollis</i>), Cockatiel (<i>Nymphicus hollandicus</i>), Red-rumped parrot (<i>Psephotus haematonotus</i>), Rose-ringed parakeet (<i>Psittacula krameri</i>), African grey parrot (<i>Psittacus erithacus</i>), domestic Canary (<i>Serinus canaria forma domestica</i>), Goldfinch (<i>Carduelis carduelis major</i>), Gouldian Finch (<i>Chloebia gouldiae</i>), Red Siskin (<i>Carduelis cucullata</i>), Australian Zebra Finch (<i>Taeniopygia castanotis</i>), and Common buzzard (<i>Buteo buteo</i>). …”
Get full text

A national population-based study of mortality and risk factors in COVID-19-hospitalized patients in Spain (2020–2021) by José-Manuel Ramos-Rincón, José-Manuel Ramos-Rincón, José Sánchez-Paya, Pilar González-De-La-Aleja, Juan-Carlos Rodríguez-Díaz, Juan-Carlos Rodríguez-Díaz, Esperanza Merino, Esperanza Merino

“…Hospitalization rates dropped from 697/100,000 people to 411/100,000, and in-hospital mortality (IHM) decreased from 16.2 to 11.5% (adjusted odds ratio [AOR]: 0.71, 95% CI: 0.70–0.73, p &lt; 0.001). IHM rose with age, from 0.8% in patients aged 18–39 to 31.7% in those ≥80 years (p &lt; 0.001), but significant decreases were observed across all age groups after vaccination, especially in those ≥80 years (AOR: 0.76, 95% CI: 0.75–0.79, p &lt; 0.001). …”
Get full text

Rapid antigen testing by community health workers for detection of SARS-CoV-2 in Dhaka, Bangladesh: a cross-sectional study by Mahbubur Rahman, Ayesha Sania, Seonjoo Lee, Tahmina Shirin, A S M Alamgir, Yael K Rayport, Ahmed Nawsher Alam, Joanna Andrecka, Eric Brum, Fergus Chadwick, Tasnuva Chowdhury, Zakiul Hasan, Davina L Hill, Farzana Khan, Mikolaj Kundegorski, Motahara Tasneem, Katie Hampson

“…Sensitivity on saliva rose to 0.48 (95% CI 0.42 to 0.54) with two additional household members tested but remained lower than sensitivity on nasal samples. …”
Get full text

Effects of <i>Lactiplantibacillus plantarum</i> on Metabolites and Flavors in Synthetic Microbiota During Baijiu Fermentation by Chunyue Yan, Xurui Chen, Quan Liu, Tengyu Xu, Qian Zhang, Xueli Jin, Bei Liao, Xiong Chen, Xin Li

“…The addition of <i>L. plantarum</i> also significantly increased the concentration of total organic acids, particularly lactic acid, which rose by 17 to 123 times. Furthermore, <i>L. plantarum</i> helped maintain the stability of ethanol concentration during the middle and late stages of fermentation. …”
Get full text

Compensatory increase in oxygen extraction fraction is associated with age-related cerebrovascular disease by John McFadden, Julian Matthews, Lauren Scott, Karl Herholz, Ben Dickie, Hamied Haroon, Oliver Sparasci, Saadat Ahmed, Natalia Kyrtata, Geoffrey J.M. Parker, Hedley C.A. Emsley, Joel Handley, Maélène Lohezic, Laura M. Parkes

“…We used a simultaneous PET-MRI protocol to measure OEF, CBF, CMRO2, and arterial transit time (ATT) in elderly people (n = 24, age 69.6 ± 5.3 years) with a range of vascular disease risk (QRisk 18.7 ± 10.8 %) and cognitive abilities (MoCA scores 26.7 ± 3.4) to determine if a) vascular disease risk (parameterised with QRisk2 score) is associated with altered CBF, ATT, OEF and CMRO2, b) if impaired blood supply and increasing transit times are associated with elevated OEF and c) if these physiological measures are associated with impaired cognition. ATT rose by 132 ms per 10 point increase in QRisk and there was a trend for reduced CBF. …”
Get full text

Effects of dietary processed former foodstuffs on slaughter performance and meat quality in broilers by Karthika Srikanthithasan, Marta Gariglio, Elena Diaz Vicuna, Margherita Profiti, Andrea Giorgino, Edoardo Fiorilla, Marta Castrica, Dino Miraglia, Sihem Dabbou, Flavia Gasperi, Ana Cristina Barroeta Lajusticia, Iolanda Altomonte, Rosalba Roccatello, Achille Schiavone, Claudio Forte

“…Breast crude protein (CP) decreased, while thigh CP and breast ether extract increased as the cFF inclusion level rose (p < .05). The fatty acid (FA) content of breast and thigh meat showed a linear increase in monounsaturated FA, with thigh meat also exhibiting a linear increase in saturated FA (SFA). …”
Get full text