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441
Comparative Genomic In Situ Hybridization and the Possible Role of Retroelements in the Karyotypic Evolution of Three Akodontini Species
Published 2017-01-01“…South American Akodontini rodents are characterized by a large number of chromosome rearrangements. …”
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442
Th17: A New Participant in Gut Dysfunction in Mice Infected with Trichinella spiralis
Published 2009-01-01“…Trichinella spiralis infection in rodents is a well-known model of intestinal inflammation associated with hypermotility. …”
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443
Patient-derived cornea organoid model to study metabolomic characterization of rare disease: aniridia-associated keratopathy
Published 2025-01-01“…Animal models, such as drosophila, zebrafish, and rodents, have been used to study aniridia through Pax6 deletions. …”
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444
Programmed Cell Death, Proliferating Cell Nuclear Antigen and p53 Expression in Mouse Colon Mucosa during Diet-Induced Tumorigenesis
Published 2000-01-01“…A major finding was an irreversible, progressive, age‐related decline of PCD at the crypt base in both control and treated animals that occurred during the second half of the rodents life span. p53 protein was not immunohistochemically detected, suggesting that neither overexpression of wild‐type nor mutated forms of the protein are involved in the above mentioned changes.…”
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445
Safety and efficacy of long-term nicotinamide mononucleotide supplementation on metabolism, sleep, and nicotinamide adenine dinucleotide biosynthesis in healthy, middle-aged Japane...
Published 2024-02-01“…Accumulating evidence from both rodents and humans suggests that the levels of nicotinamide adenine dinucleotide (NAD+), a regulator of many biological processes, declines in multiple organs and tissues with aging and obesity. …”
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446
Spinal CRH facilitates the micturition reflex via the CRH2 receptor in rats with normal bladder and bladder outlet obstruction
Published 2025-01-01“…Corticotropin-releasing hormone (CRH) is a neuropeptide that controls normal micturition in rodents. Herein, we investigated the role of spinal CRH in regulating micturition in sham and BOO rats, and evaluated CRH as a therapeutic target for bladder dysfunction in BOO model Sprague–Dawley rats. …”
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447
Fear extinction retention in children, adolescents, and adults
Published 2025-01-01“…In contrast to findings in rodents, fear conditioning in humans may elicit similar physiological responses and recruit similar neural networks from childhood to adulthood.…”
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448
ZFP36 Regulates Vascular Smooth Muscle Contraction and Maintains Blood Pressure
Published 2025-01-01“…This study reveals that ZFP36 expression is highly elevated in the arteries of hypertensive patients and rodents. In cultured vascular smooth muscle cell (VSMC), angiotensin II (AngII) activates poly (ADP‐ribose) polymerases1 (PARP1) to stimulate Zfp36 expression at the transcriptional level. …”
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449
The ultradian rhythm of glucocorticoid secretion and the time course of target gene regulation
Published 2015-07-01“…Glucocorticoid hormones (cortisol in humans and corticosterone in rodents) are secreted in discrete pulses during a day with a periodicityof approximately 1 h (ultradian rhythm), and this pattern is also maintained in plasma and extracellular fluid. …”
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450
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451
Enhanced Hepatocarcinogenicity Due to Agonists of Peroxisome Proliferator-Activated Receptors in Senescent Rats: Role of Peroxisome Proliferation, Cell Proliferation, and Apoptosis
Published 2002-01-01“…Exposure to agonists of peroxisome proliferator-activated receptor alpha (PPARα) causes liver cancer in rodents, with aged animals being more susceptible than their younger counterparts to this effect. …”
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452
Creation of a novel zebrafish model with low DHA status to study the role of maternal nutrition during neurodevelopment
Published 2025-01-01“…Embryos undergo rapid external development and are optically transparent, enabling direct observation of individual cells and dynamic cell-cell interactions in a way that is not possible in rodents. Here, we create a novel DHA-deficient zebrafish model by 1) disrupting elovl2, a key gene in the DHA biosynthesis pathway, via CRISPR/Cas9 genome editing, and 2) feeding mothers a DHA-deficient diet. …”
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453
Single, but not mixed dietary fibers suppress body weight gain and adiposity in high fat-fed mice
Published 2025-02-01“…Dietary fiber can suppress excess adipose tissue and weight gain in rodents and humans when fed high fat diets. The gut microbiome is thought to have a key role, although exactly how remains unclear. …”
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454
Adeno-Associated virus 8 delivers an immunomodulatory peptide to mouse liver more efficiently than to rat liver.
Published 2023-01-01“…To this goal, we tested the ability of Adeno-Associated Virus (AAV)8 vectors to target hepatocytes for expressing the ShK analog, ShK-235 (AAV-ShK-235) in rodents. We designed AAV8 vectors expressing the target transgene, ShK-235, or Enhanced Green fluorescent protein (EGFP). …”
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455
Avian Infectious Bronchitis Virus: Molecular Detection in Southwestern Ethiopia Chickens
Published 2024-01-01“…However, improper carcass disposal (OR = 0.43, 95% CI: 0.13–1.4), lack of veterinary services (OR = 2.7, 95% CI: 0.8–8.3), and the presence of wild birds/rodents (OR = 4.4, 95% CI: 0.88-22.3) were associated with increased IBV risk but not cleaning of feeders/drinkers (OR = 1.1, 95% CI: 0.2–4.8). …”
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456
Chromosomes and speciation in tuco-tuco (Ctenomys, Hystricognathi, Rodentia)
Published 2016-09-01“…Tuco-tucos, South American rodents of the genus Ctenomys represent an interesting model of speciation. …”
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457
Adolescent and adult mice use both incremental reinforcement learning and short term memory when learning concurrent stimulus-action associations.
Published 2024-12-01“…In a version of the human RL+WM task translated for rodents, mice were required to associate odor stimuli (from a set of 2 or 4 odors) with a left or right port to receive reward. …”
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458
The Effect of Delay Techniques on a Lassa Fever Epidemic Model
Published 2024-01-01“…The rat population includes susceptible and infectious rodents. By introducing a delay parameter and decay exponential term into the existing model in the literature, we got the system of highly nonlinear delay differential equations (DDEs). …”
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459
The role of KNDy neurons in human reproductive health
Published 2024-08-01“…Since then, studies in mice and other animals have revealed that kisspeptin is located at the apex of the hypothalamic-pituitary-gonadal axis and regulates reproductive functions by modulating gonadotropin-releasing hormone (GnRH). In rodents, kisspeptin (Kiss1) neurons localize to two regions, the hypothalamic arcuate nucleus (ARC) and the anteroventral periventricular nucleus (AVPV). …”
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460
Cilostazol Combats Lipopolysaccharide-Induced Hippocampal Injury in Rats: Role of AKT/GSK3β/CREB Curbing Neuroinflammation
Published 2024-01-01“…This study looked at the potential neuroprotective benefits of cilostazol, a phosphodiesterase inhibitor, against LPS-induced hippocampus damage in rodents and the principal molecular involvement of AKT/GSK3β/CREB signaling pathways. …”
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