Regenerative Therapy of Type 1 Diabetes Mellitus: From Pancreatic Islet Transplantation to Mesenchymal Stem Cells by Nadine E. Rekittke, Meidjie Ang, Divya Rawat, Rahul Khatri, Thomas Linn

“…Recently, they were reported to reduce hyperglycemia in diabetic rodents, and they were even discussed as being turned into endodermal or pancreatic progenitor cells. …”
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Hopeful News for Physicians Who Involved in the Treatment of Critical Aluminum Phosphide (Rice Pill) Poisoning Patients by Fatemeh Vafapour, Moslem Sedaghattalab

“…Rice tablets are commonly used in Iran due to their high efficacy against rodents and insects, low cost, and availability. Aluminum phosphide is a lethal poison without antidote and causes cardiocirculatory collapse and has negative inotropic cardiac effect. …”
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Physical Activity and Telomere Biology: Exploring the Link with Aging-Related Disease Prevention by Andrew T. Ludlow, Stephen M. Roth

“…Physical activity is associated with reduced risk of several age-related diseases as well as with increased longevity in both rodents and humans. Though these associations are well established, evidence of the molecular and cellular factors associated with reduced disease risk and increased longevity resulting from physical activity is sparse. …”
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Radiological Anatomy of the Pelvis and Pelvic Limb of the Greater Cane Rat (Thryonomys swinderianus) by Faraja H. Mpagike, Modesta Makungu

“…Despite of the pelvic limb and pelvis of greater cane rats sharing anatomical structures with other rodents, it retains some exceptional anatomical features. …”
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Why women or why not men? sex and autoimmune diseases by Gilberto Cincinelli, Elena Generali, Rajkiran Dudam, Vinod Ravindran, Carlo Selmi

“…Experimental studies on rodents demonstrate that sex chromosome abnormalities, alterations of gut microbiota composition, and fluctuations of sex hormone concentrations decrease the susceptibility to autoimmunity in female probes or increase it in the male counterparts. …”
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Anti-Arthritic Effect of the Hydroethanolic Root Extract of Psydrax subcordata in Rats by Phyllis Annan, Newman Osafo, Paul Poku Sampene Ossei, Wonder Kofi Mensah Abotsi

“…The findings show that hydroethanolic root extract of Psydrax subcordata possesses anti-inflammatory properties in rodents.…”
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A Mosquito Culex cedecei Stone and Hair (Insecta: Diptera: Culicidae) by Kristin Elizabeth Sloyer, Nathan Daniel Burkett-Cadena

“…Although Culex cedecei is not generally considered a pest of humans, it feeds primarily on muroid rodents (rats and mice), which are important hosts of EVEV in Florida. …”
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Secondary motor cortex tracks decision value during the learning of a non-instructed task by Elisabete Augusto, Vladimir Kouskoff, Nicolas Chenouard, Margaux Giraudet, Léa Peltier, Aron de Miranda, Alexy Louis, Lucille Alonso, Frédéric Gambino

“…The secondary motor cortex (M2) is key in adaptive behaviors in expert rodents, particularly in encoding decision values guiding complex probabilistic tasks. …”
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Stable Long-Term Culture of Human Distal Airway Stem Cells for Transplantation by Yueqing Zhou, Yujia Wang, Dandan Li, Ting Zhang, Yu Ma, Wei Zuo

“…Their phenotype stability in long-term cell culture was analyzed, followed by safety evaluation and tumorigenic analysis using multiple animal models including rodents and nonhuman primate. The chimerism of the human-mouse lung model indicated that DASC pedigrees could give rise to multiple epithelial types, including type I alveolar cells as well as bronchiolar secretory cells, to regenerate the distal lung. …”
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Neuroinflammation as Fuel for Axonal Regeneration in the Injured Vertebrate Central Nervous System by Ilse Bollaerts, Jessie Van houcke, Lien Andries, Lies De Groef, Lieve Moons

“…After optic nerve or spinal cord injury, inflammatory stimulation and/or modification greatly improve the regenerative outcome in rodents. Moreover, the hypothesis of a beneficial role of inflammation is further supported by evidence from adult zebrafish, which possess the remarkable capability to repair CNS lesions and even restore functionality. …”
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The Gut Microbiome Profile in Obesity: A Systematic Review by Olga Castaner, Albert Goday, Yong-Moon Park, Seung-Hwan Lee, Faidon Magkos, Sue-Anne Toh Ee Shiow, Helmut Schröder

“…Most of the studies related to microbiome and obesity have been reported based on the associations between microbiota and obesity, and the in-depth study of the mechanisms related has been studied mainly in rodents and exceptionally in humans. Due to the quantity and diverse information published, the need of reviews is mandatory to recapitulate the relevant achievements. …”
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Cannabinoid Receptors CB1 and CB2 Modulate the Electroretinographic Waves in Vervet Monkeys by Joseph Bouskila, Vanessa Harrar, Pasha Javadi, Amy Beierschmitt, Roberta Palmour, Christian Casanova, Jean-François Bouchard, Maurice Ptito

“…The expression patterns of the cannabinoid receptor type 1 (CB1R) and the cannabinoid receptor type 2 (CB2R) are well documented in rodents and primates. In vervet monkeys, CB1R is present in the retinal neurons (photoreceptors, horizontal cells, bipolar cells, amacrine cells, and ganglion cells) and CB2R is exclusively found in the retinal glia (Müller cells). …”
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Zero-echo time imaging achieves whole brain activity mapping without ventral signal loss in mice by Ayako Imamura, Rikita Araki, Yukari Takahashi, Koichi Miyatake, Fusao Kato, Sakiko Honjoh, Tomokazu Tsurugizawa

“…However, the widely used fMRI with T2*-weighted imaging in rodents has the problem of signal lack in the lateral ventral area of forebrain including the amygdala, which is essential for not only emotion but also noxious pain. …”
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Anesthetic-Induced Oxidative Stress and Potential Protection by Cheng Wang, Xuan Zhang, Fang Liu, Merle G. Paule, William Slikker, Jr.

“…Prevention of neuronal death by catalase and superoxide dismutase in vitro, or by M40403 (superoxide dismutase mimetic) in vivo, supports the contention that the involvement of reactive oxygen species (ROS) and the nature of neuronal cell death in rodents is mainly apoptotic. However, more evidence is necessary to in order verify the role of the NMDA receptor subunit NR1 and ROS in anesthetic-induced neurodegeneration.…”
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Behavioral Tagging: A Translation of the Synaptic Tagging and Capture Hypothesis by Diego Moncada, Fabricio Ballarini, Haydée Viola

“…In this review, we detail the findings supporting the existence of BT process in rodents, leading to the consolidation, persistence, and interference of a memory. …”
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Depression in Parkinson’s Disease: The Contribution from Animal Studies by Jéssica Lopes Fontoura, Camila Baptista, Flávia de Brito Pedroso, José Augusto Pochapski, Edmar Miyoshi, Marcelo Machado Ferro

“…In this review, we discuss the depression in PD, based on data from studies in humans and rodents. Depression frequency seems higher in PD patients than in general population, despite high variation in data due to diagnosis disparities. …”
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Sugammadex-Enhanced Neuronal Apoptosis following Neonatal Sevoflurane Exposure in Mice by Maiko Satomoto, Zhongliang Sun, Yushi U. Adachi, Koshi Makita

“…In rodents, neonatal sevoflurane exposure induces neonatal apoptosis in the brain and results in learning deficits. …”
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Dehydration-Induced Anorexia Reduces Astrocyte Density in the Rat Corpus Callosum by Daniel Reyes-Haro, Francisco Emmanuel Labrada-Moncada, Ricardo Miledi, Ataúlfo Martínez-Torres

“…The corpus callosum (CC) is the largest white matter tract in mammals, and more than 99% of the cell somata correspond to glial cells in rodents. Whether glial cell density is altered in anorexia is unknown. …”
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Oral Administration of Semicarbazide Limits Weight Gain together with Inhibition of Fat Deposition and of Primary Amine Oxidase Activity in Adipose Tissue by Josep Mercader, Zsuzsa Iffiú-Soltész, Sandy Bour, Christian Carpéné

“…Although SSAO physiological functions remain unclear, several molecules inhibiting its activity have been described to limit fat accumulation in preadipocyte cultures or to reduce body weight gain in obese rodents. Here, we studied whether oral administration of semicarbazide, a prototypical SSAO inhibitor, limits fat deposition in mice. …”
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CXCR2 in Acute Lung Injury by F. M. Konrad, J. Reutershan

“…CXCR2 gets activated by ELR+ chemokines, including MIP-2, KC (rodents) and IL-8 (human). Since multiple ELR+ CXC chemokines act on both receptors—CXCR1 and CXCR2—a pharmacologic agent blocking both receptors seems to be advantageous. …”
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