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301
Vectors, Hosts, and the Possible Risk Factors Associated with Severe Fever with Thrombocytopenia Syndrome
Published 2021-01-01“…Many studies have identified antigens and antibodies against SFTSV in various animals such as sheep, goats, cattle, and rodents. Besides, person-to-person transmission through contact with blood or mucous of an infected person has also been reported. …”
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302
Tofersen and other antisense oligonucleotides in ALS
Published 2025-01-01“…The results of treatment with the ASO tofersen in SOD1-ALS show that the drug has a convincing beneficial effect on ALS caused by SOD1 mutations, that preclinical studies in rodents predicted the therapeutic effect in the human disease, and that clinical efficacy is associated with a specific sequence of effects of the drug on mechanistic and degenerative biomarkers and, subsequently, functional outcomes such as weight stabilization and ALSFRS-R. …”
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303
Effects of the PPARα Agonist and Widely Used Antihyperlipidemic Drug Gemfibrozil on Hepatic Toxicity and Lipid Metabolism
Published 2010-01-01“…These events are causally related to hepatotoxicity and hepatocarcinogenicity of gemfibrozil in rodents via peroxisome proliferator activated receptor-α (PPARα) activation; however, there is widespread evidence that activation of PPARα in humans results in expression of genes involved in lipid metabolism, but not in hepatocellular proliferation.…”
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304
Spindle Bursts in Neonatal Rat Cerebral Cortex
Published 2016-01-01“…They have been observed in various neocortical areas of numerous species, including newborn rodents and preterm human infants. Spindle bursts are generated in complex neocortical-subcortical circuits involving in many cases the participation of motor brain regions. …”
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305
Updating Experimental Models of Diabetic Cardiomyopathy
Published 2015-01-01“…Inflammation, hypertrophy, fibrosis, steatosis, and apoptosis in the myocardium have been studied in numerous diabetic experimental models in animals, mostly rodents. Type I and type II diabetes were induced by genetic manipulation, pancreatic toxins, and fat and sweet diets, and animals recapitulate the main features of human diabetes and related cardiomyopathy. …”
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306
Small mammals of the suburban areas of Warsaw in the diet of the tawny owl Strix aluco
Published 2020-12-01“…In total, we recorded 611 individuals of 15 species of small mammal communities in the diet. Rodents constituted the most numerous mammalian order. …”
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307
Chronic Exposure to Arsenic in Drinking Water Causes Alterations in Locomotor Activity and Decreases Striatal mRNA for the D2 Dopamine Receptor in CD1 Male Mice
Published 2016-01-01“…Arsenic exposure has been associated with sensory, motor, memory, and learning alterations in humans and alterations in locomotor activity, behavioral tasks, and neurotransmitters systems in rodents. In this study, CD1 mice were exposed to 0.5 or 5.0 mg As/L of drinking water for 6 months. …”
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308
Activation of glutamatergic neurons in the organum vasculosum of the lamina terminalis induces thirst-driven sniffing
Published 2025-02-01“…Summary: Sniffing is a specialized respiratory behavior that enables rodents to localize and track objects in their environment. …”
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309
Nonhematopoietic Variants of Erythropoietin in Ischemic Stroke: Need for Step-Wise Proof-of-Concept Studies
Published 2010-01-01“…In view of the potential clinical use of Neuro-EPO, stringent proof-of-concept studies are urgently needed to define (1) how intranasally delivered Neuro-EPO reaches the brain, (2) which concentrations are achieved in the ischemic and nonischemic brain tissue of rodents and nonhuman primates, and (3) which are the mechanisms via which Neuro-EPO protects from injury. …”
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310
First microscopic and molecular identification of Cryptosporidium spp. in fat sand rats (Psammomys obesus) in Egypt and their potential zoonotic implications
Published 2025-01-01“…IntroductionRodents, thriving in human-altered environments, pose significant public health risks due to their role as reservoirs for numerous zoonotic parasites. …”
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311
Integrated Pest Management Policy and Treatment Options for University Housing
Published 2011-04-01“…Pest-specific IPM options are provided for ants; bed bugs; bees and wasps; birds and bats; booklice, silverfish, and earwigs; cockroaches; flies; rodents; stored product pests; termites; and weeds. …”
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312
Integrated Pest Management Policy and Treatment Options for University Housing
Published 2011-04-01“…Pest-specific IPM options are provided for ants; bed bugs; bees and wasps; birds and bats; booklice, silverfish, and earwigs; cockroaches; flies; rodents; stored product pests; termites; and weeds. …”
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313
Neurological and Neurobehavioral Disorders Associated with Toxoplasma gondii Infection in Humans
Published 2021-01-01“…Although most latent T. gondii infections in humans have traditionally been considered asymptomatic, studies in rodents suggest phenotypic neurological changes are possible. …”
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314
Mycobacteria in Terrestrial Small Mammals on Cattle Farms in Tanzania
Published 2011-01-01“…More mycobacteria were also present in insectivores as compared to rodents. All mycobacteria detected by culture and PCR in the small mammals were atypical mycobacteria. …”
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315
Relationship between enriched environment and neurodegeneration: a review from mechanism to therapy
Published 2025-01-01“…Animal models, encompassing both rodents and larger animals, offer insights into the disease-modifying effects of EE, underscoring its potential as a complementary approach to pharmacological interventions. …”
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316
Targeting the Endocannabinoid System for Prevention or Treatment of Chemotherapy-Induced Neuropathic Pain: Studies in Animal Models
Published 2018-01-01“…Almost 90% of the studies on animal models of CINP analysed utilised male rodents. Taking into consideration clinical and experimental findings that show gender differences in the mechanisms involved in pain including CINP and in response to analgesics, it is imperative that future studies on CINP utilise more female models.…”
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317
Genetic Factors in Animal Models of Intestinal Inflammation
Published 1995-01-01“…The critical importance of host genetic susceptibility in determining chronicity, aggressiveness and complications of intestinal inflammation is clearly demonstrated by studies of inbred rodents, transgenic rats and spontaneous mutants. …”
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318
Spillover: From climate change to pandemics
Published 2025-01-01“…., HIV/AIDS, Covid, SARS, mpox, Ebola) have all originated from wildlife viruses carried by bats, rodents and other animals. While some areas in Africa are projected to become too hot for malaria transmission, changing climate will allow expansion of Aedes-transmitted viral infections, such as dengue, chikungunya, and Zika, into areas with large urban populations. …”
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319
Cannabigerol and cannabichromene in Cannabis sativa L.
Published 2021-09-01“…CBC also exerts modest analgesic properties in rodents, as well as anti-fungal, anti-bacterial, pro-apoptotic, and anti-proliferative effects in tumor cells.…”
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320
Does SIRT-1 Mediate Calorie Restriction and Prolong Life? – A Mini Review
Published 2014-09-01“…Calorie restriction is the only intervention proved to prolong both average and maximum lifespan in yeast, worms, fish, rodents and possibly primates. Not only does the regimen prolong life, but it also reduces the incident of numerous age-related diseases like diabetes, atherosclerosis or cancer and slows down ageing. …”
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