Age-Dependent Switch of the Role of Serotonergic 5-HT1A Receptors in Gating Long-Term Potentiation in Rat Visual Cortex In Vivo by Peter J. Gagolewicz, Hans C. Dringenberg

“…The rodent primary visual cortex (V1) is densely innervated by serotonergic axons and previous in vitro work has shown that serotonin (5-HT) can modulate plasticity (e.g., long-term potentiation (LTP)) at V1 synapses. …”
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Life expectancy of cats in Britain: moggies and mollies live longer by Fernando Mata

“…The domestic cat (Felis catus) has been a popular companion animal for about 12,000 years, initially valued for rodent control before evolving into pets that provide affection and companionship. …”
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Transient cortical beta-frequency oscillations associated with contextual novelty in high density mouse EEG by Callum Walsh, Luke Tait, Maria Garcia Garrido, Jonathan T. Brown, Thomas Ridler

“…Abstract Beta-frequency oscillations (20–30 Hz) are prominent in both human and rodent electroencephalogram (EEG) recordings. Discrete epochs of beta (or Beta2) oscillations are prevalent in the hippocampus and other brain areas during exploration of novel environments. …”
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An interesting observation of Eurasian beaver Castor fiber Linnaeus, 1758 in Vidovec Cave (Metlika, Slovenia) by Tinkara Kepic, Meta Valenčič, Marisa Schlamberger, Tjaša Trajbarič, Łukasz Popowicz, Annasibila Požrl, Valentina Jakob, Klara Žos, Ester Premate

“… The Eurasian beaver is a common rodent which became extinct in Slovenia in the 18th century and reappeared in the 1990’s. …”
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Muscle Wasting and Resistance of Muscle Anabolism: The “Anabolic Threshold Concept” for Adapted Nutritional Strategies during Sarcopenia by Dominique Dardevet, Didier Rémond, Marie-Agnès Peyron, Isabelle Papet, Isabelle Savary-Auzeloux, Laurent Mosoni

“…However, on the long term, these nutritional strategies have often failed in improving muscle mass even if given for long periods of time in both humans and rodent models. Muscle mass loss situations have been often correlated to a resistance of muscle protein anabolism to food intake which may be explained by an increase of the anabolic threshold toward the stimulatory effect of amino acids. …”
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Developing hyperpolarized metabolic contrast agents at high field dDNP for large animal research by Ditte B. Christensen, Ingeborg S. Skre, Jan Henrik Ardenkjær-Larsen, Magnus Karlsson, Mathilde H. Lerche

“…While several metabolic substrates have been investigated at lower field dDNP and tested as HMCAs in rodents, 13C-labeled pyruvate remains the most studied HMCA and is currently the only one actively used in clinical trials due to its favorable biological and physical properties. …”
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Distribution features of the red squirrel (Sciurus vulgaris) in the south of Ukraine: a case study of Mykolaiv Oblast by Kostiantyn Redinov

“…Over the past 40 years, due to artificial and natural dispersal, this dendrophilous rodent species has significantly expanded in range into Mykolaiv Oblast, 93% of which is located within the steppe and 7% within the forest-steppe zones of Ukraine. …”
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Embryonic Stem Cell-Derived Cardiomyocyte Heterogeneity and the Isolation of Immature and Committed Cells for Cardiac Remodeling and Regeneration by Kenneth R. Boheler, Robert N. Joodi, Hui Qiao, Ondrej Juhasz, Amanda L. Urick, Sandra L. Chuppa, Rebekah L. Gundry, Robert P. Wersto, Rong Zhou

“…Following transplantation into rodent hearts, bioluminescence imaging revealed that immature cells, but not more mature CMs, survived for at least one month following injection. …”
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APT imaging of hepatocellular carcinoma signals an effective therapeutic response in advance of tumor shrinkage by Xiaojing Wang, Keisuke Ishimatsu, Junjie Li, Xiaodong Wen, Weijun Ou, Arnida Anwar, Jaideep Chaudhary, Masaya Takahashi, A Dean Sherry, Ian R Corbin

“…Aim: The aim of this study was to assess the utility of weighted amide proton transfer (APTw) MRI in three different rodent models of hepatocellular carcinoma (HCC).Methods: APTw MRI was evaluated in models of diethylnitrosamine (DEN) induced HCC, N1S1 syngeneic orthotopic xenograft and human HepG2 ectopic xenograft.Results: All models of HCC showed a higher APTw signal over the surrounding normal tissues. …”
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Age-related cerebral ventriculomegaly occurs in patients with primary ciliary dyskinesia by Franziska Eisenhuth, Joy E. Agbonze, Adam M. R. Groh, Jesse M. Klostranec, David A. Rudko, Jo Anne Stratton, Adam J. Shapiro

“…However, the impact of PCD on the central nervous system remains poorly understood. Rodent models of PCD exhibit marked hydrocephalus leading to early animal mortality, however, most humans with PCD do not develop hydrocephalus for unknown reasons. …”
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The Krushinsky – Molodkina genetic rat strain as a unique experimental model of seizure states by I. I. Poletaeva, Z. A. Kostyna, N. M. Surina, I. B. Fedotova, Z. A. Zorina

“…The specific seizure pattern, the rodent proneness for audiogenic epilepsy, as well as abnormal postictal states (catalepsy, in particular) illustrate the importance of this phenomenon not only as a model of certain brain pathology, but also as a matter of general biological importance. …”
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Activation of Sphingosine 1-Phosphate Receptor 1 Enhances Hippocampus Neurogenesis in a Rat Model of Traumatic Brain Injury: An Involvement of MEK/Erk Signaling Pathway by Yuqin Ye, Zhenyu Zhao, Hongyu Xu, Xin Zhang, Xinhong Su, Yongxiang Yang, Xinguang Yu, Xiaosheng He

“…Recent studies suggested that S1PR1 was expressed abundantly in the hippocampus, a specific neurogenic region in rodent brain for endogenous neurogenesis throughout life. …”
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Candida albicans mannans mediate Streptococcus mutans exoenzyme GtfB binding to modulate cross-kingdom biofilm development in vivo. by Geelsu Hwang, Yuan Liu, Dongyeop Kim, Yong Li, Damian J Krysan, Hyun Koo

“…In addition, these in vitro findings were confirmed in vivo using a rodent biofilm model. Specifically, we observed that C. albicans och1ΔΔ was unable to form cross-kingdom biofilms on the tooth surface of rats co-infected with S. mutans. …”
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Inactivity‐mediated molecular adaptations: Insights from a preclinical model of physical activity reduction by Alice Meyer, Nicole Kim, Melissa Nguyen, Monica Misch, Kevin Marmo, Jacob Dowd, Christian Will, Milica Janosevic, Erin J. Stephenson

“…Adult mice were randomized into three groups: an inactive control group (standard rodent housing), an active control group (treadmill running 5 d/week for 6‐weeks), and an activity reduction group (treadmill running for 4‐weeks, followed by 2‐weeks of inactivity). …”
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Dual Reporter Gene Imaging by Jiantu Che, Mikhail Doubrovin, Inna Serganova, Ludmila Ageyeva, Pat Zanzonico, Ronald Blasberg

“…The human and rodent sodium iodide symporters ( NIS ) have recently been cloned and are being investigated as potential therapeutic and reporter genes. …”
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A simple and reliable method for claustrum localization across age in mice by Tarek Shaker, Gwyneth J. Dagpa, Vanessa Cattaud, Brian A. Marriott, Mariam Sultan, Mohammed Almokdad, Jesse Jackson

“…Abstract The anatomical organization of the rodent claustrum remains obscure due to lack of clear borders that distinguish it from neighboring forebrain structures. …”
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Quantitative, Dynamic Detection of Neuronal Na+ Transients Using Multi-photon Excitation and Fluorescence Lifetime Imaging (FLIM) in Acute Mouse Brain Slices by Sara Eitelmann, Karl Kafitz, Christine Rose, Jan Meyer

“…Here, we demonstrate the use of multi-photon-based rapidFLIM with the sodium indicator ION NaTRIUM Green-2 (ING-2) for the quantitative, dynamic determination of Na+ concentrations in neurons in acute rodent brain tissue slices. We describe the loading of the dye into neurons and present a procedure for its calibration in situ. …”
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Neuroplasticity and Neuroprotective Effect of Treadmill Training in the Chronic Mouse Model of Parkinson’s Disease by Ewelina Palasz, Wiktor Niewiadomski, Anna Gasiorowska, Anna Mietelska-Porowska, Grazyna Niewiadomska

“…Physical training confers protection to dopaminergic neurons in rodent models of parkinsonism produced by neurotoxins. …”
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CRISPR/Cas9, a universal tool for genomic engineering by A. V. Smirnov, A. M. Yunusova, V. A. Lukyanchikova, N. R. Battulin

“…For instance, the CRISPR/Cas9 was recently used to control HIV infection and to repair genetic abnormalities, such as Duchenne muscular dystrophy or retinitis pigmentosa, both in cell cultures and rodent models. A programmable nature of CRISPR/Cas9 facilitates the creation of transgenic organisms through sitespecific gene mutations, knock-ins or large chromosomal rearrangements (deletions, inversions and duplications). …”
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Tppp3 is a novel molecule for retinal ganglion cell identification and optic nerve regeneration by Mishal Rao, Ziming Luo, Chia-Chun Liu, Chi-Yu Chen, Shining Wang, Michael Nahmou, Bogdan Tanasa, Aman Virmani, Leah Byrne, Jeffrey L. Goldberg, José-Alain Sahel, Kun-Che Chang

“…Here we investigated Tppp3 in retinal ganglion cells (RGCs) neuroprotection and axonal regeneration using an optic nerve crush (ONC) model in the rodent. Single-cell RNA sequencing identified the expression of Tppp3 in RGCs of mice, macaques, and humans. …”
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