GEOMETRIC PROPERTIES OF EVOLUTIONARY DISTANCES by V. M. Efimov, M. A. Melchakova, V. Yu. Kovaleva

“…The applicability of the EPQ distance is illustrated by the example of a cytochrome b sequence set of 12 rodent species from West Siberia and Altai, taken from the GenBank, and compared with the results of the use of the LogDet-distance.…”
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Serotonergic Modulation of Conditioned Fear by Judith R. Homberg

“…Understanding how neuromodulators drive the associated learning and memory processes, including memory consolidation, retrieval/expression, and extinction (recall), is essential in the understanding of (individual differences in vulnerability to) these disorders and their treatment. The human and rodent studies I review here together reveal, amongst others, that acute selective serotonin reuptake inhibitor (SSRI) treatment facilitates fear conditioning, reduces contextual fear, and increases cued fear, chronic SSRI treatment reduces both contextual and cued fear, 5-HT1A receptors inhibit the acquisition and expression of contextual fear, 5-HT2A receptors facilitates the consolidation of cued and contextual fear, inactivation of 5-HT2C receptors facilitate the retrieval of cued fear memory, the 5-HT3 receptor mediates contextual fear, genetically induced increases in serotonin levels are associated with increased fear conditioning, impaired cued fear extinction, or impaired extinction recall, and that genetically induced 5-HT depletion increases fear conditioning and contextual fear. …”
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Myoinositol: The Bridge (PONTI) to Reach a Healthy Pregnancy by Pietro Cavalli, Elena Ronda

“…In the remaining cases, no medical prevention is available, and those conditions should be defined as folate-resistant NTDs. Rodent models suggest that some folate-resistant NTDs can be prevented by inositol (myoinositol and chiroinositol) supplementation prior to pregnancy. …”
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Aseptic Meningitis Caused by Lassa Virus: Case Series Report by Peter O. Okokhere, Idowu A. Bankole, Christopher O. Iruolagbe, Benard E. Muoebonam, Martha O. Okonofua, Simeon O. Dawodu, George O. Akpede

“…We present the clinical description, laboratory diagnosis, and management of 4 consecutive cases of aseptic meningitis associated with Lassa virus infection without bleeding seen in a region of Nigeria known to be endemic for both the reservoir rodent and Lassa fever. The 4 patients recovered fully following intravenous ribavirin treatment and suffered no neurologic complications.…”
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Lassa Fever in Pregnancy: Report of 2 Cases Seen at the University College Hospital, Ibadan by O. O. Bello, O. R. Akinajo, K. H. Odubamowo, T. A. O. Oluwasola

“…Lassa fever (LF), an acute viral haemorrhagic fever, is an endemic zoonotic viral infection in West Africa countries with up to 15% case fatality rate. Though a rodent-borne infection, it can also be transmitted from person to person during the care of sick relations or more commonly in health care settings as a nosocomial infection. …”
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Acrylamide exposure: Dietary risks of oral carcinoma in non-smokers by Gokul Sudhakaran, Kuppusamy Sathishkumar, Meivelu Moovendhan

“…Exposure occurs through food and cigarette smoke. Rodent studies indicate an increased cancer risk, with acrylamide converting into glycidamide, causing DNA damage. …”
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Intraneuronal binding of amyloid beta with reelin-Implications for the onset of Alzheimer's disease. by Asgeir Kobro-Flatmoen, Stig W Omholt

“…Numerous studies of the human brain supported by experimental results from rodent and cell models point to a central role for intracellular amyloid beta (Aβ) in the onset of Alzheimer's disease (AD). …”
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Housing Complexity Alters GFAP-Immunoreactive Astrocyte Morphology in the Rat Dentate Gyrus by Garrick Salois, Jeffrey S. Smith

“…Enriched environments result in considerable neuroplasticity in the rodent brain. In the dentate gyrus of the hippocampus, enriched environments evoke especially profound neural changes, including increases in the number of neurons and the number of dendritic spines. …”
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Multiple Approaches to Investigate the Transport and Activity-Dependent Release of BDNF and Their Application in Neurogenetic Disorders by David Hartmann, Jana Drummond, Erik Handberg, Sharday Ewell, Lucas Pozzo-Miller

“…Studies utilizing genetic and pharmacological manipulations in rodent models and neuronal cultures have revealed myriad roles of brain-derived neurotrophic factor (BDNF). …”
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Assessment of food toxicology by Alexander Gosslau

“…These systems utilize a combination of complex in vitro cell-based models with computer-based algorithms. A decrease of rodent animal testing with its limitations of high costs, low throughput readouts, inconsistent responses, ethical issues and concerns of extrapolability to humans have led to an increased use of these but also alternative lower hierarchy surrogate animal models (e.g. …”
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Regulation of the G1/S Transition in Hepatocytes: Involvement of the Cyclin-Dependent Kinase Cdk1 in the DNA Replication by Anne Corlu, Pascal Loyer

“…Our article also aimed at illustrating that many discoveries in this field benefited from the combined use of in vivo models of liver regeneration and in vitro models of primary cultures of human and rodent hepatocytes. Using these models, our laboratory has contributed to decipher the different steps of the progression into the G1 phase and the commitment to S phase of proliferating hepatocytes. …”
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Rat Bite Fever Resembling Rheumatoid Arthritis by Ripa Akter, Paul Boland, Peter Daley, Proton Rahman, Nayef Al Ghanim

“…It can be very difficult to diagnose as blood cultures are typically negative and a history of rodent exposure is often missed. Unless a high index of suspicion is maintained, the associated polyarthritis can be mistaken for rheumatoid arthritis. …”
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Functional Properties of Human Stem Cell-Derived Neurons in Health and Disease by Jason P. Weick

“…In addition, novel forms of genetic manipulations have brought human stem cells nearly on par with those of rodent with respect to gene targeting. For neurons of the CNS, the ultimate phenotypic characterization lies with their ability to recapitulate functional properties such as passive and active membrane characteristics, synaptic activity, and plasticity. …”
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Midline vs. lateral flank approach for spaying nutrias (Myocastor coypus) by Francesco Di Ianni, Igor Pelizzone, Martina Gavezzoli, Martina Fumeo, Alessandro Vetere

“…The nutria (Myocastor coypus), an invasive semi-aquatic rodent in Europe introduced for the fur and meat industry at the beginning of the 20th century, has rapidly become a significant ecological and economic concern. …”
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Natural Products for Cancer Therapy: A Review of Their Mechanism of Actions and Toxicity in the Past Decade by Yasir Osman Ali Abdalla, Bavani Subramaniam, Shaik Nyamathulla, Noorasyikin Shamsuddin, Norhafiza M. Arshad, Kein Seong Mun, Khalijah Awang, Noor Hasima Nagoor

“…Besides, critical analysis of their molecular targets and underlying mechanisms on multiple cancer cell lines, an in-depth probe of their toxicological screening on rodent models is outlined as well to observe the prevalence of their toxicity towards host. …”
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Combination Treatment of C16 Peptide and Angiopoietin-1 Alleviates Neuromyelitis Optica in an Experimental Model by Yuanyuan Zhang, Kewei Tian, Hong Jiang, Beibei Wang, Shu Han

“…Moreover, NMO may cause secondary complement-dependent cytotoxicity (CDC), leading to oligodendrocyte and neuronal damage. In this study, a rodent NMO model, showing typical NMO pathogenesis, was induced with NMO-IgG from patient serum and human complement. …”
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Testosterone Replacement Therapy in the Treatment of Depression by Danyon J. Anderson, Parsia Vazirnia, Catherine Loehr, Whitney Sternfels, Jamal Hasoon, Omar Viswanath, Alan D. Kaye, Ivan Urits

“… # Results Within some subpopulations such as men with dysthymic disorder, treatment resistant depression, or low testosterone levels, testosterone administration yielded positive results in the treatment of depression. Additionally, rodent models have shown that administering testosterone to gonadectomized male animals reduces symptoms of depression. …”
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Astrocyte and Neuronal Plasticity in the Somatosensory System by Robert E. Sims, John B. Butcher, H. Rheinallt Parri, Stanislaw Glazewski

“…Changing the whisker complement on a rodent’s snout can lead to two forms of experience-dependent plasticity (EDP) in the neurons of the barrel cortex, where whiskers are somatotopically represented. …”
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X-Ray Fluorescence Microscopy Demonstrates Preferential Accumulation of a Vanadium-Based Magnetic Resonance Imaging Contrast Agent in Murine Colonic Tumors by Devkumar Mustafi, Jesse Ward, Urszula Dougherty, Marc Bissonnette, John Hart, Stefan Vogt, Gregory S. Karczmar

“…Vanadium-based chelates (VCs) selectively enhance rodent cancers on MRI, suggesting selective uptake of VCs by cancers. …”
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Analyzing the causes of alpine meadow degradation and the efficiency of restoration strategies through a mathematical modelling exercise by Hanwu Liu, Lin Wang, Fengqin Zhang, Qiuying Li, Huakun Zhou

“…We find that controlling the amount of livestock according to the grass yield or ecological migration, together with protecting raptor, is an effective strategy to restore degraded alpine meadows; while meliorating vegetation and controlling rodent population with rodenticide are conducive to restoring degraded alpine meadows. …”
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