First-in-human dose escalation trial to evaluate the clinical safety and efficacy of an anti-MAGEA1 autologous TCR-transgenic T cell therapy in relapsed and refractory solid tumors by Ignacio I Wistuba, Mamta Kalra, Linus Backert, Martin Wermke, Edwin R Parra, Jason John Luke, Apostolia M Tsimberidou, Sebastian Bunk, Mohammad B Hossain, Andrea Mayer-Mokler, Arun Satelli, Norbert Hilf, Steffen Walter, Cedrik M Britten, Van K Morris, Tobias A W Holderried, Winfried H Alsdorf, Katrin Wetzko, Borje S Andersson, Sandra Grund-Gröschke, Katrin Aslan, Anantha Marisetty, Swapna Satam, Jens Hukelmann, M Alper Kursunel, Karine Pozo, Andreas Acs, Melissa Baumeister, Claudia Wagner, Oliver Schoor, Ali S Mohamed, Delfi Krishna

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Tobacco control environment: cross-sectional survey of policy implementation, social unacceptability, knowledge of tobacco health harms and relationship to quit ratio in 17 low-inc... by Annika Rosengren, Li Wei, Khalid Yusoff, Martin McKee, Clara K Chow, Rajeev Gupta, Koon Teo, Sumathy Rangarajan, Patricio Lopez-Jaramillo, Rafael Diaz, Alvaro Avezum, Fernando Lanas, Noorhassim Ismail, Romaina Iqbal, Jephat Chifamba, Gilles Dagenais, Salim Yusuf, Anna B Gilmore, Scott Lear, Wang Yang, Omar Rahman, Katarzyna Zatonska, Prem Mony, Rajesh Kumar, Afzalhussein Yusufali, Daniel J Corsi, Ehimario Igumbor, V Mohan, Annamarie Kruger, Krishnapillai Vijayakumar, Yuksel Altuntas, Ahmad Bahonar

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Chronic lung lesions in COVID-19 survivors: predictive clinical model by Paulo A Lotufo, Juliana C Ferreira, Eloisa Bonfa, Anna S Levin, Rodrigo Caruso Chate, Marta Imamura, Esper G Kallas, Roger Chammas, Thais Mauad, Izabel Marcilio, Nelson Gouveia, Ricardo Nitrini, José Eduardo Krieger, Marcio Valente Yamada Sawamura, Michelle Louvaes Garcia, Cristiano Gomes, Guilherme Fonseca, Jorge Hallak, Luis Yu, Marcio Mancini, Maria Elizabeth Rossi, Thiago Avelino-Silva, Edivaldo M Utiyama, Aluisio C Segurado, Beatriz Perondi, Anna Miethke-Morais, Amanda C Montal, Leila Harima, Marjorie F Silva, Marcelo C Rocha, Maria Amélia de Jesus, Carolina Carmo, Clarice Tanaka, Julio F M Marchini, Thaís Guimarães, Ester Sabino, Carlos Roberto Ribeiro Carvalho, Celina Almeida Lamas, Diego Armando Cardona Cardenas, Daniel Mario Lima, Paula Gobi Scudeller, João Marcos Salge, Cesar Higa Nomura, Marco Antonio Gutierrez, Adriana L Araújo, Bruno F Guedes, Carolina S Lázari, Cassiano C Antonio, Claudia C Leite, Emmanuel A Burdmann, Euripedes C Miguel, Fabio R Pinna, Fabiane Y O Kawano, Geraldo F Busatto, Giovanni G Cerri, Heraldo P Souza, Izabel C Rios, Larissa S Oliveira, Linamara R Batisttella, Luiz Henrique M Castro, Marcello M C Magri, Maria Cassia J M Corrêa, Maria Cristina P B Francisco, Maura S Oliveira, Orestes V Forlenza, Ricardo F Bento, Rodolfo F Damiano, Rossana P Francisco, Solange R G Fusco, Tarcisio E P Barros-Filho, Wilson J Filho

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I-SPY COVID adaptive platform trial for COVID-19 acute respiratory failure: rationale, design and operations by Carolyn S Calfee, Michael A Matthay, Paul Henderson, Martin Eklund, Laura J Esserman, Chirag Patel, Angela Haczku, Michelle Jung, Tony Oliver, Alessio Crippa, Andrea Discacciati, Kathleen D Liu, Ellen L Burnham, Nuala J Meyer, Fady A Youssef, Derek W Russell, Julie Lang, Kevin W Gibbs, Daniel C Files, Sheetal Gandotra, Purnema Madahar, Nathan K Cobb, Timothy E Albertson, Rajiv Sonti, John P Reilly, Alejandra Jauregui, Iván García, Luis E Huerta, Daniel Clark Files, Neil R Aggarwal, Adam L Asare, Jeremy R Beitler, Paul A Berger, George Cimino, Melissa H Coleman, Paul T Henderson, Caroline A G Ittner, Kashif T Khan, Jonathan L Koff, Mary LaRose, Joe Levitt, Ruixiao Lu, Jeffrey D McKeehan, Karl W Thomas, Aaron M Mittel, Albert F Yen, Alexis E Suarez, Alexis L Serra, Alpesh N Amin, Amanda Rosen, Amy L Dzierba, Anna D Barker, Ariel R Weisman, Brian M Daniel, Brian M Morrissey, Caroline AG Ittner, Chayse Jones, Christina Creel-Bulos, Christina M Angelucci, Diana Ng, Fredy Chaparro-Rojas, Gavin H Harris, Harsh V Barot, Heny Su, Jacqueline B Sutter, Jamal Dodin, Jerry S Lee, John Kazianis, Joshua F Detelich, Julie E Lang, Justin Muir, Katarzyna Gosek, Katherine L Nugent, Kimberly Yee, Laura G Rodrigues, Laura R Macias, Lindsey A Orr, Lindsie L Boerger, Lissette Rosario-Remigio, Lucia Kufa, Maged Tanios, Maria B Reyes, Max W Adelman, Maya M Juarez, Michelle Meyers, Mitchell P Sternlieb, Neil Aggarwal, Nilam S Mangalmurti, Patrice Jones, Paul L Saban, Peter S Marshall, Philiip A Robinson, Philip Yang, Rahul Nair, Richard Anthony Lee, Richard G Wunderink, Romina Wahab, Roxana A Lupu, Santhi I Kumar, Sara C Auld, Scott Fields, Se Fum Wong, Skyler J Pearson, Spencer Whealon, Timothy F Obermiller, Anita Darmanian, John Schicchi, Esmeralda Martinez, Farjad Sarafian, Julie Nguyen, Bethany Weiler-Lisowski, Jaime Wyatt, Daniel Blevins, Marylee Melendrez, Brenda Lopez, Hiwet Tzehaie, Omowunmi Amosu, Austin Simonson, Erin Hardy, Brett Lindgren, Gregory Peterfreund, Leigha Landreth, Lisa Parks

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A systematic analysis of the contribution of genetics to multimorbidity and comparisons with primary care dataResearch in context by Olivia Murrin, Ninon Mounier, Bethany Voller, Linus Tata, Carlos Gallego-Moll, Albert Roso-Llorach, Lucía A. Carrasco-Ribelles, Chris Fox, Louise M. Allan, Ruby M. Woodward, Xiaoran Liang, Jose M. Valderas, Sara M. Khalid, Frank Dudbridge, Sally E. Lamb, Mary Mancini, Leon Farmer, Kate Boddy, Jack Bowden, David Melzer, Timothy M. Frayling, Jane A.H. Masoli, Luke C. Pilling, Concepción Violán, João Delgado

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The implementation of genome sequencing in rare genetic diseases diagnosis: a pilot study from the Hong Kong genome projectResearch in context by Wai Kei Jacky Lam, Chak Sing Lau, Ho Ming Luk, Lisa Wing Chi Au, Gary C.P. Chan, Will Yap Hang Chan, Shirley Sze Wing Cheng, Timothy Hua Tse Cheng, Li Li Cheung, Yiu Fai Cheung, Josephine Shuk Ching Chong, Annie Tsz Wai Chu, Claudia Ching Yan Chung, Kin Lai Chung, Cheuk Wing Fung, Eva Lai Wah Fung, Yuan Gao, Stephanie Ho, Shirley Pik Ying Hue, Chi-Ho Lee, Tsz Leung Lee, Philip Hei Li, Hei Man Lo, Ivan Fai Man Lo, Herbert Ho Fung Loong, Becky Mingyao Ma, Wei Ma, Shirley Yin Yu Pang, Wai-Kay Seto, Steven Wai Kwan Siu, Ho So, Yuk Him Tam, Wenshu Tang, Rosanna Ming Sum Wong, Desmond Yat Hin Yap, Maggie Lo Yee Yau, Brian Hon Yin Chung, Su-Vui Lo

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A 5-transcript signature for discriminating viral and bacterial etiology in pediatric pneumonia by Sandra Viz-Lasheras, Alberto Gómez-Carballa, Jacobo Pardo-Seco, Xabier Bello, Irene Rivero-Calle, Ana Isabel Dacosta, Myrsini Kaforou, Dominic Habgood-Coote, Aubrey J. Cunnington, Marieke Emonts, Jethro A. Herberg, Victoria J. Wright, Enitan D. Carrol, Stephane C. Paulus, Werner Zenz, Daniela S. Kohlfürst, Michiel Van der Flier, Ronald de Groot, Luregn J. Schlapbach, Philipp Agyeman, Andrew J. Pollard, Colin Fink, Taco T. Kuijpers, Suzanne Anderson, Cristina Calvo, María del Carmen Martínez-Padilla, Ana Pérez-Aragón, Esteban Gómez-Sánchez, Juan Valencia-Ramos, Francisco Giménez-Sánchez, Paula Alonso-Quintela, Laura Moreno-Galarraga, Ulrich von Both, Marko Pokorn, Dace Zavadska, María Tsolia, Clementien L. Vermont, Henriëtte A. Moll, Michael Levin, Federico Martinón-Torres, Antonio Salas

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Attitudes towards vaccines and intention to vaccinate against COVID-19: a cross-sectional analysis—implications for public health communications in Australia by Leslie Swartz, Jean Bourbeau, Naja Hulvej Rod, Colleen Norris, Molly Byrne, Samir Gupta, Juhee Cho, Amos Laar, Jacqueline Boyle, Eva Suarthana, Mohsen Sadatsafavi, Bronwynè Coetzee, Susan Michie, Richard Fleet, Jason Bantjes, Beate Ditzen, Justin Presseau, Lucie Byrne-Davis, Claudia Gemme, Valeria Raparelli, Alexandra Kautzky-Willer, Sandra Peláez, Hannah Durand, Olivier Drouin, Sze Man Tse, Louise Pilote, Hagai Levine, Richard Ayah, Drieda Zaçe, Paul Poirier, Helena J Teede, Paula Griffiths, Elizabeth W Kimani-Murage, Lisa Kakinami, Angelos Kassianos, Chiwoza Bandawe, Ariane Belanger-Gravel, Lise Gauvin, Ilda Hoxhaj, Stefania Boccia, Jovana Stojanovic, Keven Joyal-Desmarais, Emily Petherick, Joanne Liu, Linda Booij, Joanne Enticott, Ahmed Abou-Setta, Kyle Warkentin, Roland Grad, Michael Vallis, Gary Garber, Mohsen Alyami, Johannes Thrul, Gregory Ninot, Susanne Fischer, Lauren Sherar, Paula Simão, Daniel Akunga, Jackim Nyamari, John Bosco Isunju, Michel Fournier, Francine Ducharme, Sarah Bernard, Shawn Aaron, Susan Bondy, Rizwana Roomaney, Jiyoung Lee, Violet Naanyu, Chris Noone, Abdhalah Ziraba, Eli Puterman, Jaskirath Singh Gill, Simon L. Bacon, Kim L. Lavoie, Daniel S. Epstein, Shrinkhala Dawadi, Zahir Vally, Analía Verónica Losada, Shajedur Rahman Shawon, Arobindu Dash, Marilia Estevam Cornelio, Darlan Lauricio Matte, Angela Alberga, Tracie Barnett, Silvana Barone, Lisa Maureen Birch, Roxane Borgès Da Silva, Rachel Burns, Tavis Campbell, Linda Carlson, Kim Corace, Mohsen Farhadloo, Carl Falk, Jennifer Gordon, Kim Hellemans, Catherine Herba, Heungsun Hwang, Jack Jedwab, Eric Kennedy, Sunmee Kim, Joshua Rash, Paula A B Ribeiro, Paramita Saha Chaudhuri, Nicolás Bronfman Caceres, Manuel Ortiz, Paula Beatriz Repetto, Mariantonia Lemos-Hoyos, Mathieu Beraneck, Thomas Kubiak, Sam Codjoe, Lily Kpobi, Naorem Kiranmala Devi, Sanjenbam Meitei, Suzanne Tanya Nethan, Lancelot Pinto, Kallur Nava Saraswathy, Dheeraj Tumu, Silviana Lestari, Grace Wangge, Jennifer McSharry, Oonagh Meade, Gerry Molloy, Anat Zaidman-Zait, Stefania Paduano, Ala'S Aburub, Chris Barasa, Pamela Miloya Godia, Nicholas Mutuku, Teresa Mwoma, Hildah Oburu, Joyce Olenja, Dismas Ongore, Loh Siew Yim, Andrea Herbert, Daniela Liggett, Ademola Ajuwon, Nisar Ahmed Shar, Bilal Ahmed Usmani, Rosario Mercedes Bartolini Martínez, Hilary Creed-Kanashiro, Pierre Claver Rutayisire, Abu Zeeshan Bari, Iveta Nagyova, Brendon Barnes, Ashraf Khagee, Tebogo Mothiba, Man-gyeong Lee, Anne Berman, Nouha Saleh Stattin, Debbie Hu, Yasin Kara, Ceprail Şimşek, Bilge Üzmezoğlu, James Mugisha, Joanne Hart, Will Johnson, Nicola Paine, Robert M Bilder, Matthew Burg, Susan Czajkowski, Ken Freedland, Sherri Sheinfeld Gorin, Alison Holman, Gilberto Lopez, Sylvie Naar, Michele Okun, Lynda Powell, Sarah Pressman, Tracey Revenson, John Ruiz, Sudha Sivaram, Claudia Trudel-Fitzgerald, Abehaw Yohannes, Rhea Navani, Kushnan Ranakombu, Daisuke Hayashi Neto, Tair Ben-Porat, Anda Dragomir, Amandine Gagnon-Hébert, Vincent Gosselin Boucher, Mahrukh Jamil, Lisa Maria Käfer, Ariany Marques Vieira, Tasfia Tasbih, Maegan Trottier, Robbie Woods, Reyhaneh Yousefi, Tamila Roslyakova, Lilli Priesterroth, Shirly Edelstein, Tanya Goldfrad, Ruth Snir, Yifat Uri, Comfort Sanuade, Olivia Crescenzi, Katya Grinko, Lalita Angne, Jigisha Jain, Nikita Mathur, Anagha Mithe, Sarah Nethan

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Addressing Shortcomings in Contingency Standards of Care by Alexander Quan

“…The Lancet Rheumatology, 3(2), e83. https://doi.org/10.1016/S2665-9913(21)00001-1 [14] For an example of transition planning between crisis and contingency standards, see Minnesota Department of Health. (2021). …”
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Paraneoplastic Autoimmunity Associated with Testicular Myeloid Sarcoma and Chronic Myelomonocytic Leukemia by Jeffrey W. Craig, Richard J. Lin

“…Clinicians must recognize the common association between possible paraneoplastic rheumatologic symptoms and hematologic malignancies such as chronic myelomonocytic leukemia.…”
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Whole-Body 18FDG-PET in an Arthritis Paraneoplastic Syndrome Revealed an Underlying Hematological Neoplasm by Serge Cammilleri, Marie Caroline Guzian, Jean-Pierre Mattei, Olivier Mundler, Sandrine Guis

“…About 4% of patients with lymphoma or leukemia suffered from rheumatologic paraneoplastic symptoms like arthralgia and about 10% of the patients with rheumatologic or neurologic clinical symptoms develop a solid cancer or hematological neoplasm. 18FDG-PET is an interesting exam to identify an underlying malignancy when a paraneoplastic syndrome is suspected; it can detect the primitive lesion and/or the metastasis lesions. …”
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The effects of magnesium supplementation in autoimmune rheumatic diseases by Aaron Lerner, Jozélio Freire de Carvalho, Carina Benzvi, Motti Haimi

“…However, its role in rheumatological diseases has been barely investigated. …”
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Diving into Diagnostic Complexity: A Case Study of Spontaneous Hemothorax by Maryam Sarkhosh, Atiyeh Sadat Sajadi, Omid Moradi Moghaddam, Parisa Moradi Majd

“…Despite inconclusive rheumatologic tests, evaluations excluded malignancies and thromboembolic events, enabling transfusions and supportive care. …”
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Diplopia: A Rare Manifestation of Neuroborreliosis by Ayushi Dixit, Yesika Garcia, Lauren Tesoriero, Charles Berman, Vincent Rizzo

“…Early disseminated Lyme disease typically presents with cardiac, rheumatologic, or neurologic symptoms. Though uncommon, Borrelia burgdorferi can invade the central nervous system and cause neuroborreliosis. …”
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Goldenhar Syndrome Associated with Extensive Arterial Malformations by Renee Frances Modica, L. Daphna Yasova Barbeau, Jennifer Co-Vu, Richard D. Beegle, Charles A. Williams

“…Given dilation, a rheumatologic workup ensued, only identifying few weakly positive autoantibodies. …”
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A Survey of Canadian Gastroenterologists about the Use of Methotrexate in Patients with Crohn’s Disease by Nilesh Chande, Terry Ponich, James Gregor

“…Still, there are no guidelines for monitoring patients with CD on MTX, and physicians must decide based on rheumatological literature about how to monitor their patients.…”
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Primary Meningococcal Polyarthritis in an Adult Woman by José Celso Giordan Cavalcanti Sarinho, Marília Soares e Silva Arcadipane, Graziela Tavares Miola Menezes, Danilo Fernando Costa Duarte, Waldenise Cossermelli, Ivan Aprahamian

“…This case report aims to briefly review this rare clinical event in an adult woman with no previous history of rheumatological disease. Early diagnosis of polyarthritis caused by meningococcal bacteria usually present a good prognosis when properly treated.…”
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Bilateral Destructive Hip Disease from Untreated Juvenile Idiopathic Arthritis by Arash Calafi, Alton W. Skaggs, Trevor J. Shelton, Brian M. Haus

“…Pediatric patients presenting with rapidly evolving destructive process should be evaluated for rheumatologic, infectious, and spinal etiologies.…”
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When the Benign Pneumatosis Intestinalis Becomes No Longer Benign: A Rare Case of Bowel Perforation in a Patient with Systemic Sclerosis by Jian Guan, Alvina Munaf, Alric V. Simmonds, Irteza Inayat

“…Benign pneumatosis intestinalis, a phenomenon more frequently seen in rheumatologic conditions, makes the diagnosis of colonic perforation even more challenging. …”
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Diabetic Cheiroarthropathy: A Case Report and Review of the Literature by Rabia Cherqaoui, Sheldon McKenzie, Gail Nunlee-Bland

“…Diabetes mellitus is associated with a wide variety of rheumatologic manifestations which can significantly affect a patient's quality of life. …”
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