Mental health in the COVID-19 pandemic: A longitudinal analysis of the CLoCk cohort study. by Laura Panagi, Simon R White, Snehal M Pinto Pereira, Manjula D Nugawela, Isobel Heyman, Kishan Sharma, Terence Stephenson, Trudie Chalder, Natalia K Rojas, Emma Dalrymple, Kelsey McOwat, Ruth Simmons, Olivia Swann, CLoCk Consortium, Tamsin Ford, Roz Shafran

“…There are mixed findings from systematic reviews of how the pandemic affected CYP's mental health, which may be due to heterogeneous methods and poor quality studies. …”
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Accuracy of algorithms to identify patients with a diagnosis of major cancers and cancer-related adverse events in an administrative database: a validation study in an acute care h... by Takashi Fujiwara, Yasuyuki Okumura, Hironobu Tokumasu, Takashi Kanemitsu, Kosei Tajima, Akinori Yuri, Masahiro Iwasaku

“…This study was conducted to evaluate the accuracy of diagnosis and adverse event (AE) definitions for specific cancers in a Japanese health administrative real-world database (RWD).Design and setting Retrospective observational validation study to assess the diagnostic accuracy of electronic medical records (EMRs) and claim coding regarding oncology diagnosis and AEs based on medical record review in the RWD. The sensitivity and positive predictive value (PPV) with 95% CIs were calculated.Participants The validation cohort included patients with lung (n=2257), breast (n=1121), colorectal (n=1773), ovarian (n=216) and bladder (n=575) cancer who visited the hospital between January 2014 and December 2018, and those with prostate cancer (n=3491) visiting between January 2009 and December 2018, who were identified using EMRs.Outcomes Key outcomes included primary diagnosis, deaths and AEs.Results For primary diagnosis, sensitivity and PPV for the respective cancers were as follows: lung, 100.0% (96.6 to 100.0) and 81.0% (74.9 to 86.2); breast, 100.0% (96.3 to 100.0) and 74.0% (67.3 to 79.9); colorectal, 100.0% (96.6 to 100.0) and 80.5% (74.3 to 85.8); ovarian, 89.8% (77.8 to 96.6) and 75.9% (62.8 to 86.1); bladder, 78.6% (63.2 to 89.7) and 67.3% (52.5 to 0.1); prostate, 100.0% (93.2 to 100.0) and 79.0% (69.7 to 86.5). …”
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Novel Clinical Insights into the Pathogenesis of Posttraumatic Elbow Stiffness: An Expression Profile Analysis of Contracted Joint Capsule in Human by Liu N, Dong J, Li L, Xu J, Yang C, Yu Z, Liu F

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Assessment of The Factors Affecting Management of Gender and Sexual Violence Against Women in Rural Communities: A Case Study of Kyanamira Sub County Kabale District. by Tumuheki, Timothy

“…The emerging themes and opinions were properly analyzed, and compared with the information that was obtained in the literature review. Data was then manually analyzed using a calculator and presented in chronological and logical order. …”
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Research progress of auricular point therapy to relieve preoperative period anxiety before elective surgery in adults (耳穴压豆缓解成年人择期手术术前焦虑的研究进展)... by GAO Yuan (高原), XU Lingzhi (徐凌志), LI Suxia (李素霞)

“…However, current research on auricular acupressure primarily focuses on postoperative scenarios, specific diseases, or types of surgery. Through literature review and analysis, this paper summarizes the application of auricular acupressure in alleviating preoperative anxiety among adults undergoing elective surgery and discusses its physiological mechanisms, providing a reference for clinical practice. …”
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Effectiveness and safety of PD-1/L1 inhibitors as first-line therapy for patients with advanced or metastatic urothelial carcinoma who are ineligible for platinum-based chemotherap... by Weiming Liang, Weiming Liang, Zhijing Wang, Zhilong Huang, Yanping Huang, Chunyan Li, Yiwen Liang, Miaoyan Huang, Duo Zhang, Chenchen Li

“…Specifically, the combination of Enfortumab vedotin (EV) and pembrolizumab (Pembro) showed more effectiveness in treating patients compared to trials using the current standard treatment, suggesting that it could be a promising alternative treatment option.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/, identifier CRD42024510152.…”
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plaTform fOr Urinary tract infection diagnostiC evAluatioN (TOUCAN): a protocol for a prospective diagnostic accuracy study of point-of-care testing in patients suspected of acute... by Thomas R Fanshawe, Philip J Turner, Gail N Hayward, Margaret Glogowska, Alastair D Hay, Michael Moore, Mark Lown, Christopher C Butler, Mandy Wootton, Mark H Wilcox, Jane Freeman, Nicola Kenealy, Valerie Tate, Owain Llion, Rebecca Lowe

“…We will publish the findings of The plaTform fOr Urinary tract infection diagnostiC evAluatioN evaluations in peer-reviewed medical journals and more broadly following a dissemination plan formulated by a communications specialist in consultation with patients and the public.Trial registration number ISRCTN80937472.…”
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Factors associated with caffeine intake among undergraduates: a cross-sectional study from Palestine by May Hamdan, Souzan Zidan, Fatima Al-Amouri, Hiba Niroukh, Manar Abu Dawod, Sajeda Ashour, Shahd Sameer Dweik, Manal Badrasawi

“…The content validity of the FFQ was done by three reviewers. Also, a questionnaire was used to collect data related to sociodemographic characteristics, medical history, lifestyle habits, sleeping quality, physical activity, and psychological status. …”
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Usability and Usefulness of a Symptom Management Coaching System for Patients With Cancer Treated With Immune Checkpoint Inhibitors: Comparative Mixed Methods Study by Savannah Lucia Caterina Glaser, Itske Fraterman, Noah van Brummelen, Valentina Tibollo, Laura Maria Del Campo, Henk Mallo, Sofie Wilgenhof, Szymon Wilk, Vitali Gisko, Vadzim Khadakou, Ronald Cornet, Manuel Ottaviano, Stephanie Medlock

“…Participants were asked to review the concept of the tool, perform think-aloud tasks, and complete the System Usability Scale and a Perceived Usefulness questionnaire. …”
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The role of Anti-PAD4, Anti-CarP, and Anti-RA33 antibodies combined with RF and ACPA in predicting abatacept response in rheumatoid arthritis by Alberto Floris, Maria Maddalena Angioni, Mattia Fadda, Micaela Rita Naitza, Mattia Congia, Elisabetta Chessa, Matteo Piga, Alberto Cauli

“…The RF and ACPA status were retrospectively assessed by reviewing the patients’ clinical records. Positivity for aPAD4, aCarP and aRA33 were determined by Enzyme-Linked Immunosorbent Assay (ELISA). …”
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Adaptive Just-in-Time Intervention to Reduce Everyday Stress Responses: Protocol for a Randomized Controlled Trial by Jillian A Johnson, Matthew J Zawadzki, Martin J Sliwinski, David M Almeida, Orfeu M Buxton, David E Conroy, David Marcusson-Clavertz, Jinhyuk Kim, Robert S Stawski, Stacey B Scott, Christopher N Sciamanna, Paige A Green, Emily M Repka, Meynard John L Toledo, Nicole L Sturges, Joshua M Smyth

“…The Pennsylvania State University Institutional Review Board approved all study procedures (STUDY00012740). …”
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Glaucoma Detection and Feature Identification via GPT-4V Fundus Image Analysis by Jalil Jalili, PhD, Anuwat Jiravarnsirikul, MD, Christopher Bowd, PhD, Benton Chuter, MD, Akram Belghith, PhD, Michael H. Goldbaum, MD, Sally L. Baxter, MD, Robert N. Weinreb, MD, Linda M. Zangwill, PhD, Mark Christopher, PhD

“…Design: Evaluation of multimodal large language models for reviewing fundus images in glaucoma. Subjects: A total of 300 fundus images from 3 public datasets (ACRIMA, ORIGA, and RIM-One v3) that included 139 glaucomatous and 161 nonglaucomatous cases were analyzed. …”
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Myocardial Infarction-Associated Shock: A Comprehensive Analysis of Phenotypes, SCAI Classification, and Outcome Assessment by Stanislav Dil, Maria Kercheva, Oleg Panteleev, Sergey Demianov, Aleksandr Kanev, Nina Belich, Boris Kornienko, Vyacheslav Ryabov

“…<i>Materials and Methods</i>: In this single-center, retrospective observational study, we reviewed the medical records of 1289 patients admitted to the emergency cardiology department from 1 January to 12 December 2020. …”
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Protocol for a multisite randomised controlled trial assessing the effect of the Telehealth for Early Developmental Intervention in babies born very preterm (TEDI-Prem) programme o... by Alicia J Spittle, Peter J Anderson, Angela T Morgan, Rachel Schembri, Li Huang, Kim Dalziel, Rod W Hunt, Katherine Lee, Anne E Holland, Karli Treyvaud, Abbey L Eeles, Stacey Dusing, Shaaron Brown, Susan M Fehring, Gillian Henty, Elizabeth Kozaris

“…Findings will be disseminated through peer-reviewed publications, conference presentations, digital and print media and to participants.Trial egistration number This trial is registered with the Australian New Zealand Clinical Trials Registry (ACTRN12621000364875).…”
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ABO-incompatible liver transplantation – exploring utilitarian solutions to restricted access and organ shortages: A single-centre experience from Johannesburg, South Africa by E U Wessels, J Loveland, H Maher, P Gaylard, B Bobat, A D Mahomed, D Parbhoo, M R Beretta, C Hajinicolaou, P Walabh, S Berkenfeld, D Demopoulos, S Rambarran, B Ströbele, F van der Schyff, J Fabian, L Brannigan

“…This retrospective record review compared all adult and paediatric patients receiving ABO-compatible (ABOc) and ABO-incompatible (ABOi) liver transplants from January 2014 to December 2021 with a minimum one-year follow-up. …”
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Unravelling the role of secretory Immnuoglobulin-A in COVID-19: a multicentre study in nursing homes during the first wave by Rafael Bielza, Patricia Pérez, Nuria García, Laura Ballesteros-Sanabria, Rosa María Martínez, Azam Ghazi, Clara Hernando, María Victoria Rodríguez, Israel J. Thuissard, Cristina Andreu-Vázquez, José Manuel Bautista

“…Resident medical records were reviewed to assess symptoms, comprehensive geriatric assessment (CGA), reinfection, and overall 30-day mortality. …”
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Mamá Empoderada: study protocol for a pilot trial of a novel parenting and mental health prevention intervention for migrant mothers with young children at the Mexico-US border by Gudelia Rangel, Shira M Goldenberg, Eileen Pitpitan, Kaylee Ramage, Ietza Bojorquez-Chapela, Cecilia Martinez-Torteya, Katherine Rosenblum, Chelsie Hernandez, Monica Alvarez

“…In collaboration with our community partners, results will be disseminated via peer-reviewed publications; presentations; and plain-language reports, infographics, and presentations to community, clinical, and policy audiences. …”
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Five years comparation of efficacy and safety after ICL-V4c implantation for high and super high myopia correction by Qi Wan, Li Chen, Peiyuan He, Ran Wei, Ke Ma, Hongbo Yin, Jing Tang, Ying-ping Deng

“…Objectives The objective of the investigation is to examine the long term efficacy, safety, and predictability of ICL-V4c implantation for high and super-high myopic patients in order to provide reliable guidance for the selection of refractive surgical procedures.Methods We reviewed 125 eyes from 64 patients who implanted ICL-V4c at the Refractive Surgery Center of West China Hospital in Chengdu, China, between May 2015 and January 2017. …”
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Immune-related adverse events with PD-1/PD-L1 inhibitors: insights from a real-world cohort of 2523 patients by Ting Yan, Minghui Long, Chaoyi Liu, Jiwen Zhang, Jiwen Zhang, Xingyu Wei, Xingyu Wei, Fei Li, Fei Li, Dehua Liao

“…We documented patients’ demographic and clinical characteristics, PD-1 or PD-L1 inhibitors, treatment modalities, incidences, timing, and severity of irAEs, and efficacy outcomes by reviewing inpatient records. Patients were categorized into an irAEs group and a non-irAEs group, with the former further subdivided into a multiple irAEs group and a single irAE group. …”
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Study protocol for key interventions to improve the follow-up adherence postcervical precancerous lesion treatment in Ethiopia: a pragmatic randomised controlled trial by Adamu Addissie, Eva Johanna Kantelhardt, Eric Sven Kroeber, Sefonias Getachew, Muluken Gizaw, Abel Shita, Alemnew Destaw, Eyerusalem Getachew, Miresa Midaksa, Sophie Rossner

“…Descriptive statistics, χ2 test (Fisher’s exact test), binary logistic regression analysis and intention-to-treat will be used to describe and interpret the results.Ethics and dissemination The trial protocol has been approved by the institutional review board of Addis Ababa University with protocol number (008/24/SPH). …”
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