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Re-annotation of SARS-CoV-2 proteins using an HHpred-based approach opens new opportunities for a better understanding of this virus
Published 2024-11-01“…We first show that the C-terminal part of Spike S (the protein that binds the virion to the cell membrane by interacting with the host receptor, triggering infection) has similarities with the human prominin-1/CD133; after reviewing what is known about prominin-1/CD133, we suggest that the C-terminal part of Spike S could both improve the docking of Spike S to ACE2 (the main cell entry receptor for SARS-CoV-2) and be involved in the delivery of virions to regions where ACE2 is located in cells. …”
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A novel interpretable deep learning model for diagnosis in emergency department dyspnoea patients based on complete data from an entire health care system.
Published 2024-01-01“…Gold standard diagnoses were defined as the subsequent in-hospital or ED discharge notes, and a subsample was manually reviewed by emergency medicine experts. A novel deep learning model, the clinical attention-based recurrent encoder network (CareNet), was developed. …”
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Macular edema after retinal vein occlusions. Macular morphometry and chorioretinal hemodynamics
Published 2021-09-01“… Fedorov NMRC “MNTK “Eye Microsurgery”, <br> </b><b> </b><b>Khabarovsk, Russian Federation</b> </p> <p> <b><sup>2</sup>Far Eastern State Medical University, Khabarovsk, Russian Federation</b> </p> <p> <b><sup>3</sup>Institute of Advanced Training of Healthcare Specialists, Khabarovsk, <br> </b><b> </b><b>Russian Federation</b> </p> <p> <i>This review article summarizes current data on the pathogenesis of macular edema after retinal vein occlusions (RVOs) and patterns of macular morphometry and chorioretinal hemodynamics. …”
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Comprehensive safety evaluation of isatuximab in multiple myeloma using disproportionality analysis of FAERS and meta-analysis of randomized controlled trials
Published 2024-12-01“…For the meta-analysis, safety outcomes of isatuximab in adult patients were reviewed from RCTs sourced from databases such as PubMed, EMBASE, and ClinicalTrials.gov, employing a random-effects meta-analysis to determine the risk ratio (RR) with 95% CI. …”
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Factores que influyen en la decisión de licitar o no licitar en la Franja de Gaza - perspectivas de los contratistas Factors affecting bid/no bid decision in the Gaza Strip -contra...
Published 2011-01-01“…A total of seventy-eight factors were identified through a comprehensive literature review to evaluate the most important factors that affect the contractors' decisions to bid or not in the Gaza strip. …”
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Synthesizing the impact of armed conflicts on food security, livelihoods and social dynamics in Amhara region, Ethiopia
Published 2025-02-01“…The primary data were supplemented by a review of reports from credible secondary sources. …”
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Determinants of Success in Revision Cochlear Implant Surgeries: A Comprehensive Evaluation of Patient, Surgical, and Radiological Factors
Published 2025-01-01“…Data were collected from systematic chart reviews of electronic medical records, including demographics, surgical techniques, radiological output from standard high-resolution CT and MRI, and intraoperative data. …”
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Continuous ambulatory peritoneal dialysis technique failure in adult patients treated at a tertiary hospital in central South Africa: a retrospective analytical study
Published 2025-01-01“…Methods We conducted a retrospective analytical study reviewing files of patients with end-stage kidney disease (ESKD) whose peritoneal dialysis (PD) catheter was removed, or who died with a functioning PD catheter while on the PD program at Universitas Academic Hospital in Bloemfontein, South Africa, from 01 January 2015 until 31 December 2019. …”
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