Targeted therapy and immunotherapy for gastric cancer: rational strategies, novel advancements, challenges, and future perspectives by Dong Luo, Yunmei Liu, Zhengmao Lu, Lei Huang

“…Herein we systematically review the current status of and advancements in targeted therapy and immunotherapy for GC, which have emerged as important treatment strategies in recent years with great potential, and summarize the efficacy and safety of such treatments. …”
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Strongly Coupled 𝒫𝒯-Symmetric Models in Holography by Daniel Areán, David Garcia-Fariña, Karl Landsteiner

“…Generically, <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mi mathvariant="script">PT</mi></semantics></math></inline-formula>-symmetric non-Hermitian theories can also feature phases where <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mi mathvariant="script">PT</mi></semantics></math></inline-formula> symmetry is broken and unitarity is lost. We review the construction of holographic duals to strongly coupled <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mi mathvariant="script">PT</mi></semantics></math></inline-formula>-symmetric quantum field theories and the study of their phase diagram. …”
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Biofilm as a supracellular organization of pathogenic bacteria by B.P. Kuzminov, K.D. Mazhak

“…Therefore, there is an increased attention of scientists to the study of the anti-biofilm effect of new compounds and drugs capable of influencing energy or metabolic processes in cells, as well as substances that do not require a metabolically active target. The review illustrates general modern approaches to the use of QS chains in pathogenic bacteria as new therapeutic targets.…”
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Analysis of factors affecting the clinical management of infection in culture-negative patients following percutaneous endoscopic decompression: a retrospective study by Changpeng Qu, Haixin Wei, Hao Zhang, Zheng Lian, Hui Lu, Shuo Han

“…The patients’ medical records were reviewed. Patient demographics, hidden blood loss, daily blood glucose control, and maximum temperature during treatment were recorded as potential risk factors. …”
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Ocular hypertension after silicone oil filling surgery for high myopia: a case-control study by Xiaodan Lin, Shenghui Feng, Chunmei Chen, Yadan Xiong, Na Li, Ling Tong

“…Method In this retrospective analysis, we reviewed 214 eyes from 432 patients diagnosed with severe myopia, all of whom underwent vitrectomy and were treated with silicone oil filling. …”
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Prevalence and Intensity of Intestinal Helminth Infections in Preschool Pupils in Lugari Subcounty, Kakamega County, Kenya by Daniel Kevin Werunga, Elizabeth Nanjala Omukunda, Jackson Cheruiyot Korir

“…Approval of the study was sought from the Masinde Muliro University of Science and Technology Institutional Ethical Review Board (MMUST IRB). The overall prevalence of intestinal helminths was 12.3%. …”
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Development of a Prognostic Nomogram Incorporating the Naples Prognostic Score for Postoperative Oral Squamous Cell Carcinoma Patients by Xu XL, Cheng H

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Accepting your Body after Cancer (ABC), a group-based online intervention for women treated for breast cancer: study protocol for a feasibility randomised controlled trial by Sarah Byford, Abigail Jones, Shelley Potter, Paul White, Diana Harcourt, Helena Lewis-Smith, Patricia Fairbrother

“…The findings will be disseminated to academic and health professionals via a peer-reviewed publication and presentations at relevant conferences. …”
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Alström syndrome: the journey to diagnosis by Akshat Sinha, Kerry Leeson-Beevers, Catherine Lewis, Elizabeth Loughery, Tarekegn Geberhiwot

“…The process involved a combination of interviews with families, social care and education reviews. Interviews were semi-structured using open questions and a patient-centred approach. …”
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Interfacial and mass transport phenomena in the tri-ethylene glycol-methane system at process conditions of natural gas dehydration by Stanley Ibeh, Philip Jaeger

“…This study experimentally investigates the interfacial and transport behavior of systems comprising tri-ethylene glycol (TEG) and methane (CH4) under conditions relevant to the gas dehydration process. A comprehensive review of the interfacial tension (IFT) and diffusivity of systems involving non-polar and polar compounds at elevated pressures was studied. …”
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Recent global patterns in skin cancer incidence, mortality, and prevalence by Mingyue Wang, Xinghua Gao, Li Zhang, Lishao Guo, Xiangxiang Pan

“…The incidence and mortality rates of skin cancer (melanoma of skin and non-melanoma skin cancer) in GLOBOCAN 2022 were reviewed. These data were analyzed and the characteristics of incidence and mortality across five continents and top five countries and regions in each continent are presented. …”
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Empirical analysis of control models for different converter topologies from a statistical perspective by Hole Shreyas Rajendra

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The clinical journey of belantamab mafodotin in relapsed or refractory multiple myeloma: lessons in drug development by Pralay Mukhopadhyay, Hesham A. Abdullah, Joanna B. Opalinska, Prani Paka, Eric Richards, Katja Weisel, Suzanne Trudel, Maria-Victoria Mateos, Meletios Athanasios Dimopoulos, Sagar Lonial

“…Despite the 41% response rate and durable responses observed with belantamab mafodotin in the Phase III confirmatory DREAMM-3 trial, the marketing license for belantamab mafodotin was later withdrawn from US and European markets when the trial did not meet its primary endpoint of superiority for progression-free survival compared with pomalidomide and dexamethasone. This review reflects on key lessons arising from the clinical journey of belantamab mafodotin in RRMM. …”
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Demographics, Presenting Features, and Outcomes of Adult Patients with Ocular Trauma by Leanne M. Clevenger, Jessica L. Cao, Megan S. Steinkerchner, Amy S. Nowacki, Alex Yuan

“…This is a retrospective chart review of examination and imaging findings for ocular trauma and how they correlate with treatment course and visual acuity (VA) outcomes. …”
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The neuroendocrine stress-response in insects: the history of the development of the concept by M. A. Eremina, N. E. Gruntenko

“…This reaction is universal and appears in response to stimuli that are unusual not just for living and habitat of the species, but also for each population. Here we review a progressive change of theoretical concepts, approaches and methods of research in this scientific field: beginning with the development of the stress concept by H. …”
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Significance of immune factors in Crohn's disease development by D. S. Stavtsev, T. A. Astrelina, O. V. Knyazev, T. V. Pukhlikova

“…The aim of review. To analyze modern approach to pathogenesis of Crohn's diseases (CD), to determine effect of individual immunogenetic factors on development and progression of disease, in particular, in relation to HLA profile.Summary. …”
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The TikTok Addiction Scale: Development and validation by Petros Galanis, Aglaia Katsiroumpa, Ioannis Moisoglou, Olympia Konstantakopoulou

“…Considering that the use of TikTok is increasing rapidly and the fact that TikTok addiction may be a different form of social media addiction, there is an urge for a valid tool to measure TikTok addiction.ObjectiveTo develop and validate a tool to measure TikTok addiction.MethodsFirst, we performed an extensive literature review to create a pool of items to measure TikTok addiction. …”
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Diagnostic accuracy of MRI-based radiomic features for EGFR mutation status in non-small cell lung cancer patients with brain metastases: a meta-analysis by Yuqin Long, Rong Zhao, Xianfeng Du

“…However, the variability in diagnostic performance across different studies underscores the need for standardized radiomic protocols to enhance reproducibility and clinical utility.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/, identifier CRD42024544131.…”
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Causal Association Between Skin Microbiota and Malignant Melanoma: Genetic Insights From Mendelian Randomization by Li X, Wu S, Pan Y, Wu Z, Du Z, Xie W, Zhou Q

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An analysis of heavy silicone oil treatment for inferior proliferative vitreoretinopathy by Maximilian Hammer, Amanda Ie, Katharina Eibenberger, Gerd Uwe Auffarth, Kanmin Xue

“…Trial registration Analyses were conducted as an internal quality improvement audit and as such did not require external IRB review.…”
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