Glimepiride monotherapy versus combination of glimepiride and linagliptin therapy in patients with HNF1A-diabetes: a protocol for a randomised, double-blinded, placebo-controlled t... by Torben Hansen, Tina Vilsbøll, Filip Krag Knop, Alexander Sidelmann Christensen, Heidi Storgaard, Sofie Hædersdal

“…Positive, negative and inconclusive results will be published at scientific conferences and as one or more scientific manuscripts in peer-reviewed journals with authorship in accordance with the International Committee of Medical Journal Editors’ recommendations.Trial registration number 2017-000204-15.…”
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Towards Equitable Diabetes Care: A Global Perspective on Quality Measurement Exchange by Alon Rasooly, Orly Manor, Ruitai Shao, Moriah E. Ellen, Nadav Davidovitch

“…Employing a realist evaluation methodology, we conducted database searches for peer-reviewed articles, international organizations’ documents, and country-level reports. …”
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Barriers and enablers in the micronutrient powder supply chain: lessons from a process evaluation of a home fortification programme in Bangladesh by Md. Fakhar Uddin, Md. Aminul Islam, Mahfuzur Rahman, Tahmeed Ahmed, Haribondhu Sarma

“…We conducted 15 Key Informant Interviews (KIIs) with HF programme personnel, 41 In-depth Interviews (IDIs) with direct HF programme implementers and reviewed relevant documents. We analyzed data using thematic and root-cause analysis approaches.ResultsParticipants reported the barriers in the MNP supply chain included lack of raw materials for MNP production by local manufacturer, political unrest and insufficient transport facilities, a lack of space for MNP buffer stock at BRAC’s central warehouse, and coordination gaps between BRAC’s national and sub-national level staff. …”
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Quantitative and O2 Enhanced MRI of the Pathologic Lung: Findings in Emphysema, Fibrosis, and Cystic Fibrosis by Alfred Stadler, Leopold Stiebellehner, Peter M. Jakob, Johannes F. T. Arnold, Edith Eisenhuber, Isabella von Katzler, Alexander A. Bankier

“…Gas exchange is the primary function of the lung and the transport of oxygen plays a key role in pulmonary physiology and pathophysiology. The purpose of this review is to present a short overview of the relaxation mechanisms of the lung and the current technical concepts of T1 mapping and methods of oxygen enhanced MR imaging. …”
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Prevalence of occult endometrial carcinoma in patients with endometrial intraepithelial neoplasia who underwent hysterectomy by Waraphon Thongsang, Sompop Kuljarusnont, Suchanan Hanamornroongruang, Irene Ruengkhachorn

“…An expert gynecologic pathologist reviewed pathological slides. Data collected from medical records included demographic and gynecologic information, sonographic findings, and surgical and pathological outcomes. …”
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Robotic-assisted costectomy using a Gigli saw for fibrous dysplasia by Chen Yang, Lei Chen, Hui Wang, Qianyun Wang

“…In this study, we present a novel technique for three-port robotic-assisted costectomy utilizing a Gigli saw, detailing our initial findings and outcomes. Methods We reviewed five patients with benign rib tumors who underwent three-port robotic-assisted rib resection using a Gigli saw between May 2021 and December 2022. …”
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Evaluating Adult Cystic Fibrosis Care in BC: Disparities in Access to a Multidisciplinary Treatment Centre by James M. Roberts, Pearce G. Wilcox, Bradley S. Quon

“…We performed a retrospective chart review of 168 patients who accessed CF care primarily through the St. …”
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Vitreous Decompression Combined with Phacoemulsification for Medically Unresponsive Acute Angle Closure by Xiaoli Xiang, Yuan Chen, Jinyu Wang, Zhengru Huang, Zheng Gu

“…This study evaluated a technique of vitreous needle aspiration combined with phacoemulsification for the treatment of acute angle closure with continuous high intraocular pressure (IOP). We retrospectively reviewed the results of vitreous needle aspiration combined with phacoemulsification in 17 eyes (17 patients) with acute angle closure with continuous high IOP and coexisting visually significant cataracts between September 2018 and April 2020 at the glaucoma unit of the affiliated Changshu Hospital of Xuzhou Medical University. …”
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Microbiota, parasitic infections and their relationship with nutritional status and neurocognitive functioning in children from Ecuador—Proyecto Guagua: research protocol for a cro... by Sandra Victoria Abril-Ulloa, Tannia Valeria Carpio-Arias, Renata Alejandra Alvarado-Barba, Cristina Gabriela Ríos-Romero, Pamela Vinueza-Veloz, Sueny Paloma Lima-dos-Santos, Sueny Paloma Lima-dos-Santos, Igor Eduardo Astudillo-Skliarova, Igor Eduardo Astudillo-Skliarova, Ruth Irene Arias-Gutiérrez, Manuel Pérez-Quintana, Henk-Jan Boele, Henk-Jan Boele, Henk-Jan Boele, María Fernanda Vinueza-Veloz

“…The findings of “Proyecto Guagua” will be disseminated through open-access, peer-reviewed publications and presented at local and international scientific events.…”
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Risk characterisation of chemicals of emerging concern in real-life water reuse applications by Jan C. Specker, Antonia Praetorius, Milo L. de Baat, Nora B. Sutton, Annemarie P. van Wezel

“…Therefore, an extensive literature review was performed to identify current water reuse practices at field scale, reported types and levels of CECs and their associated risks for human and environmental health. …”
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Research progress of femoral head necrosis in HIV-infected patients by Youhan Yang, Futao Ke, Zhengqi Pan, Liaobin Chen

“…This represents a promising avenue for future research. The present article reviews the epidemiological study of HIV-infected patients with osteonecrosis of the femoral head, local changes of the femoral head, possible mechanisms of osteonecrosis of the femoral head, occupational exposure during treatment, and surgical efficacy. …”
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Improving community-based first response to out of hospital cardiac arrest (FirstCPR): protocol for a cluster randomised controlled trial by Sandra Ware, Blake Angell, Julie Redfern, Clara Chow, Cate Ferry, Lee Taylor, Christopher Semsarian, Adrian Bauman, Janet E Bray, Simone Marschner, Michael Nelson, Saurabh Kumar, Matthew Vukasovic, Kevin Lai, Paul M Middleton, Pramesh Kovoor, Garry Jennings, Sonali Munot, Andrew Coggins, Alan Robert Denniss, Sarah Khanlari, Ian Opperman

“…Findings from this study will be disseminated via presentations at scientific conferences, publications in peer-reviewed journals, scientific and lay reports.Trial registration number ACTRN12621000367842.…”
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Stem Cell Therapy for the Treatment of Amyotrophic Lateral Sclerosis: Comparison of the Efficacy of Mesenchymal Stem Cells, Neural Stem Cells, and Induced Pluripotent Stem Cells by Lauren Frawley, Noam Tomer Taylor, Olivia Sivills, Ella McPhillamy, Timothy Duy To, Yibo Wu, Beek Yoke Chin, Chiew Yen Wong

“…Current research targets molecular mechanisms of inflammation, excitotoxicity, aggregation-prone proteins, and proteinopathy. Methods: This review evaluates the efficacy of three stem cell types in ALS treatment: mesenchymal stem cells (MSCs), neural stem cells (NSCs), and induced pluripotent stem cells (iPSCs). …”
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Multi-level lag scheme significantly improves training efficiency in deep learning: a case study in air quality alert service over sub-tropical area by Benedito Chi Man Tam, Su-Kit Tang, Alberto Cardoso

“…The research methods include literature review, searching for relevant technology frontiers, feasibility studies, selection and design solutions, modeling, data collection and pre-processing, experiments, evaluation, comprehensive analysis and conclusions. …”
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Functional Skin Grafts: Where Biomaterials Meet Stem Cells by Amtoj Kaur, Swati Midha, Shibashish Giri, Sujata Mohanty

“…In addition, with newer biomaterials being adopted for fabricating patient-specific skin substitutes, issues related to escalating processing costs, scalability, and stability of the constructs under in vivo conditions have raised some concerns. This review provides an overview of the field of skin regenerative medicine, existing clinical therapies, and limitations of the current techniques. …”
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Liver cystic echinococcosis: A retrospective study on the demographics and clinical profile of patients managed at a single tertiary institution in central Eastern Cape Province, S... by A Govindasamy, P R Bhattarai, J van Niekerk, J John

“…A 4-year (2019 - 2022) retrospective clinical record review study was conducted on patients presenting with liver CE to the Department of Surgery at Frere Hospital. …”
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Protocol of a randomised controlled phase II clinical trial investigating PREoperative endoscopic injection of BOTulinum toxin into the sphincter of Oddi to reduce postoperative pa... by Phillip Knebel, Thilo Hackert, Markus W Büchler, Thomas Bruckner, Peter Sauer, Markus K Diener, Christine Tjaden, Ulla Klaiber, Pascal Probst, Eike Martin, Steffen Luntz

“…The results of the trial will be presented at national and international conferences and published in a peer-reviewed journal.Trial registration number DRKS00020401.…”
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Ethnotherapeutic Uses and Phytochemical Composition of Physalis peruviana L.: An Overview by Félicien Mushagalusa Kasali, Jonans Tusiimire, Justin Ntokamunda Kadima, Casim Umba Tolo, Anke Weisheit, Amon Ganafa Agaba

“…Physalis peruviana L. is among the most used plants in conventional medication worldwide. This review aimed to highlight the ethnotherapeutic uses and phytochemical status of identified compounds in P. peruviana. …”
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Ambient fine particulate matter provokes multiple modalities of cell death via perturbation of subcellular structures by Yán Wāng

“…Fine particulate matter (PM2.5) is increasingly recognized for its detrimental effects on human health, with substantial evidence linking exposure to various forms of cell death and dysfunction across multiple organ systems. This review examines key cell death mechanisms triggered by PM2.5, including PANoptosis, necroptosis, autophagy, and ferroptosis, while other forms such as oncosis, paraptosis, and cuprotosis remain unreported in relation to PM2.5 exposure. …”
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Exchange Nailing for Aseptic Nonunion of the Femoral Shaft after Intramedullary Nailing by Sung-Soo Ha, Chang-Wug Oh, Jae-Wook Jung, Joon-Woo Kim, Kyeong-Hyeon Park, Seong-Min Kim

“…Methods We retrospectively reviewed 30 cases of aseptic femoral shaft nonunion after intramedullary nailing. …”
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