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34681
Developing a codesigned text message-based digital oral health education resource (TOOTH)
Published 2025-01-01“…Methods A total of three focus groups (one clinician and two consumers) were conducted to identify themes that were used to draft text message content. The study team reviewed, refined, and mapped these messages to behaviour change techniques and developed videos to support key concepts. …”
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34682
Stroke Mortality, Clinical Presentation and Day of Arrival: The Atherosclerosis Risk in Communities (ARIC) Study
Published 2011-01-01“…The presence or absence of thirteen stroke signs and symptoms were obtained through medical record review for each event. Binomial logistic regression was used to estimate odds ratios and 95% confidence intervals (OR; 95% CI) for the association between weekend arrival and 28-day mortality for all stroke events and for stroke subtypes. …”
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34683
Metformin in COVID-19: a magical role beyond the hyperglycemia
Published 2024-07-01“…These characteristics gave rise to a hypothesis that metformin may find use as an efficacious treatment for COVID-19 especially if it decreases the inflammatory molecules that fuel the COVID-19 virus-induced effects. In this review, we attempt to elucidate the role of classical anti-diabetic medicine metformin in the treatment of COVID-19 infections by highlighting the pharmacological role of this drug during elevated glucose levels and insulin resistance. …”
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34684
Chromatin remodeling (SWI/SNF) complexes, cancer, and response to immunotherapy
Published 2022-09-01“…Remarkable, although anecdotal, responses to ICB have been reported in both SMARCA4-aberrant and SMARCB1-aberrant advanced cancers. This review focuses on the role that SWI/SNF chromatin remodeling subunits play in carcinogenesis, the immune microenvironment, and in immunotherapy responsiveness.…”
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34685
Propensity score matched comparison of lymph node upstaging in early-stage lung cancer: open versus minimally invasive surgery with standardized lymphadenectomy
Published 2025-01-01“…Methods This retrospective study reviewed data of all patients undergoing lobectomy at the Lung Tumor Center Munich between 2011 and 2020. …”
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34686
ESTABLISHING THE KEY ELEMENTS OF INCORPORATION AND OUTCOMES OF 4TH INDUSTRIAL REVOLUTION IN BUILT ENVIRONMENT EDUCATION: A MIXED BIBLIOGRAPHIC AND BIBLIOMETRIC ANALYSIS
Published 2020-09-01“…The study utilised a verifiable and reproducible systematic literature review of digital education; with analysis and scrutiny of 582 academic articles for the co-occurrence of keywords, using a mixed bibliographic and bibliometric method. …”
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34687
Effect of blindfolding the lead resuscitator on frequency of closed-loop communication during veterinary cardio-pulmonary resuscitation training: a randomized, controlled pilot stu...
Published 2025-01-01“…The intervention involved the lead resuscitator wearing a blindfold during the third of four CPR simulation scenarios for the BG groups only.Measurements and main resultsVideo footage of Scenarios 2 (before) and 4 (after) the intervention was reviewed to quantify complete CLCs. Quantitative data were analyzed, and descriptive statistics calculated using GraphPadPrism (GraphPadPrism, Version9.3.1(350) forMacOSX, GraphPadSoftware, SanDiego, CA). …”
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34688
Immediate Post-laparotomy Hypotension in Patients with Severe Traumatic Hemoperitoneum
Published 2020-03-01“…After applying those criteria, 62 patients were enrolled in this retrospective review. PLH was defined as a decrease in the mean arterial pressure (MAP) ≥10 mmHg within 10 minutes after laparotomy. …”
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34689
Prognosis of premenopausal women with low-risk endometrial cancer but elevated CA125 levels
Published 2025-01-01“…The characteristics of the eligible women were collected from seven institutes in the Republic of Korea by reviewing their medical records. Recurrence-free survival (RFS) was estimated using the Kaplan–Meier method and compared using the log-rank test.ResultsSeventy-three patients were included. …”
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34690
Organization of the fight against COVID-19 in a hospital institution. Cienfuegos Province, 2020-2021
Published 2023-02-01“…Human resources and availability of beds for patient care were also taken into account. The After Action Review method was applied to study lessons learned. …”
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34691
Clinical and bacteriological characteristics of Corynebacterium keratitis
Published 2025-01-01“…Methods We retrospectively reviewed cases of bacterial keratitis in which Corynebacterium species were solely isolated from corneal scraping cultures collected at Ehime University Hospital between January 2010 and February 2024. …”
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34692
Transcriptional Systems Vaccinology Approaches for Vaccine Adjuvant Profiling
Published 2025-01-01“…Transcriptomics tools such as RNA sequencing (RNA-Seq) allow us to simultaneously quantify the expression of practically all expressed genes, making it possible to make inferences that are only possible when considering the system as a whole. Here, we review some of the challenges in adjuvant studies, such as predicting adjuvant activity and toxicity when administered alone or in combination with antigens, or classifying adjuvants in groups with similar properties, while underscoring the significance of transcriptomics in systems vaccinology approaches to propel vaccine development forward.…”
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34693
Study protocol for a randomised controlled trial on the use of intraoperative ultrasound-guided laparoscopic ovarian cystectomy (UGLOC) as a method of fertility preservation in the...
Published 2022-07-01“…We aim to randomise 94 patients over 3 years to achieve power of 80% at an alpha level of 0.05.Ethics and dissemination Findings will be published in peer-reviewed journals and presented at national and international conferences and scientific meetings. …”
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34694
Opioid-related harms and experiences of care among people in justice settings in New South Wales, Australia: evidence from the National Ambulance Surveillance System
Published 2025-01-01“…People in justice settings were identified using ambulance billing codes and manual review of paramedic case notes. Descriptive statistics described the patterns and modalities of opioid-related harms in justice settings, and a qualitative thematic analysis of paramedic case notes was used to contextualise findings. …”
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34695
Assessment of factors implicated in bone fusion after percutaneous endoscopic lumbar intervertebral fusion
Published 2024-11-01“…Methods: This single-center retrospective study reviewed the medical records of 96 patients who underwent single-level PELIF for degenerative pathologies between 2018 and 2020. …”
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34696
Can Gastric Cancer Patients with High Mandard Score Benefit from Neoadjuvant Chemotherapy?
Published 2022-01-01“…Mandard scores and ypN stage of postoperative pathological reports were recorded. The results were reviewed by a professional pathologist. The radiologist compared the tumor regression before and after chemotherapy by computed tomography (CT). …”
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34697
Crafting dental specialities in Iran: insights from a qualitative study
Published 2025-01-01“…Methods A qualitative case study was carried out, involving the review of 25 in-depth interviews and 47 documents. …”
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34698
Radiopharmaceuticals and their applications in medicine
Published 2025-01-01“…Diagnostic radiopharmaceuticals play a pivotal role in patient stratification and treatment planning, leading to improved therapeutic outcomes in targeted radionuclide therapy. This review offers a comprehensive overview of the evolution of radiopharmaceuticals, including both FDA-approved and clinically investigated agents, and explores the mechanisms of cell death induced by radiopharmaceuticals. …”
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34699
Deciphering the pseudouridine nucleobase modification in human diseases: From molecular mechanisms to clinical perspectives
Published 2025-01-01“…Cellular stresses trigger RNA pseudouridylation in organisms, suggesting that pseudouridylation‐mediated epigenetic reprogramming is essential for maintaining cellular viability and responding to stress. This review examines the regulatory mechanisms and pathological implications of pseudouridylation in human diseases, with a focus on its involvement in tumourigenesis. …”
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34700
Biodiversity conservation policy reform and reconciliation in Canada: an analysis of the pathway to Canada target 1 through the policy cycle model
Published 2025-01-01“…This is fundamental in reconciliation and in the improvement of conservation policies. After a review of the history and structure of the Pathway, paying attention to the importance of building relationship with Indigenous Peoples early in the policy process, we use the policy cycle model, outlining five stages of the policy process, to enable our analysis. …”
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