The use of screening, identification, assessment and support policy to support vulnerable learners by Inneth Baby Makofane, Simon Mfula Ndlovu, Hunadi Mphahlele, Mahlapahlapana Johannes Themane

“…Data was collected through semi-structured interviews and document review. The data were analysed thematically. The study revealed misconception of the SIAS policy, the incredibility of school-based support teams, inappropriate learner profiling, lack of comprehensive psychosocial support systems, poor parental involvement, the teachers’ preparedness in contributing towards enabling schooling environments. …”
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Research Progress on the Structure and Function, Immune Escape Mechanism, Antiviral Drug Development Methods, and Clinical Use of SARS-CoV-2 M^pro by Jiayi Ren, Zhengfu Zhang, Yi Xia, Daqun Zhao, Dingqin Li, Shujun Zhang

“…Consequently, it has become an important target for the development of SARS-CoV-2-specific drugs. This review summarizes the recent research progress on the novel coronavirus’s main proteases, including the pivotal role of M^pro in the virus’s life cycle, the structure and catalytic mechanism of M^pro, the self-maturation mechanism of M^pro, the role of M^pro in virus immune escape, the current methods of developing antiviral drugs targeting M^pro, and the key drugs that have successfully entered clinical trials. …”
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Design and Optimization of the Circulatory Cell-Driven Drug Delivery Platform by Pengyu Gao, Dan Zou, Ansha Zhao, Ping Yang

“…Generally, employing cells from the blood circulatory system as cargo carriers has achieved great benefits and paved the way for tumor diagnosis and therapy. This review specifically covers (a) the properties of red blood cells, monocytes, macrophages, neutrophils, natural killer cells, T lymphocytes, and mesenchymal stem cells; (b) the loading strategies to balance cargo amounts and cell function balance; (c) the cascade strategies to improve cell-driven targeting delivery efficiency; and (d) the features and applications of cell membranes, artificial cells, and extracellular vesicles in cancer treatment.…”
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Health benefits of algae and marine-derived bioactive metabolites for modulating ulcerative colitis symptoms by Najmeh Oliyaei, Saghar Zekri, Aida Iraji, Alireza Oliyaei, Romina Tanideh, Nadiar M. Mussin, Amin Tamadon, Nader Tanideh

“…It has been reported that algal sulfated polysaccharides, peptides, pigments, polyphenols, and marine oil are useful for controlling ulcerative colitis via different pathways including modulating of TNF-α and other related inflammatory cytokines secretion, increasing the antioxidant enzymes [superoxide dismutase (SOD) and catalase(CAT)] activities, reduction of myeloperoxidase (MPO) activity and malondialdehyde (MDA) production, improving the intestinal barrier function and repairing histological damage in the colon. This review focused on the pathology of ulcerative colitis, pathogenesis and key inflammatory pathways, and the role of algae and marine-based metabolites for reduction of ulcerative colitis signs via alleviating the inflammation cytokines secretion, and improving the barrier function and gut microbiota.…”
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ANALYSIS OF PUBLIC SAFETY CENTER 119 AMBULANCE SERVICES USING LEAN SIX SIGMA by Thasya Sabilla Putri Rojak, Masyitoh Basabih, Winarto, Roy Michael Suranta

“…The data were collected through observations, document reviews, and in-depth interviews. Results: The results showed that the average duration of ambulance services was 4 hours and 30 minutes. …”
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Prenatal Diagnosis of Complete Atrioventricular Septal Defect: Perinatal and Neonatal Outcomes by Gokhan Yıldırım, Kemal Gungorduk, Fehmi Yazıcıoğlu, Ahmet Gul, Fatma Çakar, Özgü Çelikkol, Yavuz Ceylan

“…Methods. We retrospectively reviewed fetal echocardiograms diagnosed with cAVSD from January 2002 to December 2007, comparing fetuses with and without aneuploidy. …”
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Induced Pluripotent Stem Cells: Generation Strategy and Epigenetic Mystery behind Reprogramming by Pengfei Ji, Sasicha Manupipatpong, Nina Xie, Yujing Li

“…More importantly, the applications of iPSC in the development of disease models such as neurodegenerative disorders greatly enhance our understanding of the pathogenesis of such diseases and also facilitate the development of clinical therapeutic strategies using iPSC generated from patient somatic cells to avoid an immune rejection. In this review, we highlight the advances in iPSCs generation methods as well as the mechanisms behind their reprogramming. …”
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A Protective Role of Canonical Wnt/β-Catenin Pathway in Pathogenic Bacteria-Induced Inflammatory Responses by Zhongjia Jiang, Weiping Zhou, Xing Tian, Peng Zou, Ning Li, Chunmeng Zhang, Yanting Li, Guangyan Liu

“…It is assumed that an inflammatory milieu is necessary for initiating and activating this signaling, implying that Wnt activity is responsible for shielding tissues from overwhelming inflammation, thus sustaining a balanced physiological condition against bacterial infection. This review gathers the recent efforts to elucidate the mechanistic details through how Wnt/β-catenin signaling modulates anti-inflammatory responses in response to bacterial infection and its interactions with other inflammatory signals, which warrants further study for the development of specific interventions for the treatment of inflammatory diseases. …”
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Vision Loss and Recovery after Baerveldt Aqueous Tube Shunt Implantation by Esther Lee Kim, Jeffrey Tran, Marc Töteberg-Harms, Jasdeep Chahal, Douglas Rhee, Vikas Chopra, Brian Francis

“…This study aims to determine the course of vision loss after Baerveldt aqueous tube shunt placement and identify risk factors associated with unexplained severe long-term vision loss, or snuff-out. We retrospectively reviewed 247 eyes of 222 patients who underwent Baerveldt implantations at one of two academic institutions. …”
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Multidisciplinary approach to functional somatic syndromes: study protocol for a population-based prospective cohort study by Hamidreza Roohafza, Harold Snieder, Fatemeh Hadizadeh, Peyman Adibi, Alireza Ani, Ahmad Vaez

“…Study findings will be disseminated through peer-reviewed publications and presentations at scientific meetings.…”
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Do cytokines play a role in the transition from acute to chronic musculoskeletal pain? by Andrea Ebersberger, Hans-Georg Schaible

“…In numerous experimental non-human studies, cytokines have been shown to alter neuronal sensitivity in the peripheral and central nociceptive systems. In this review, we addressed the involvement of cytokines in postoperative pain, complex regional pain syndrome, rheumatoid arthritis, osteoarthritis, temporomandibular joint disease, low back pain and fibromyalgia using PubMed searches including meta-analyses of data. …”
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A workplace organisational intervention to improve hospital nurses’ and physicians’ mental health: study protocol for the Magnet4Europe wait list cluster randomised controlled tria... by Peter Griffiths, Jonathan Drennan, Jackie Bridges, Luk Bruyneel, Jane Ball, Linda H Aiken, Douglas M Sloane, Anners Lerdal, Matthew McHugh, Herbert Smith, Anne Marie Rafferty, Reinhard Busse, Walter Sermeus, Julia Köppen, Lars E Eriksson, Kaat Siebens, Matthew D McHugh, Anne Scott, Ingeborg Strømseng Sjetne, Sydney Anstee, Peter Van Bogaert, Rikard Lindqvist, Linda Aiken, Douglas Sloane, Hans De Witte, Wilmar B Schaufeli, Hans De Witte, Simon Dello, Dorothea Kohnen, Claudia Bettina Maier, Lisa Smeds Alenius, Mary Del Guidice, Timothy Cheney, Claudia Maier, Joan Kleine, Elaine Lehane Vera McCarthy, Noeleen Brady, Monica Bukkøy Kjetland, Paul Van Aken, Danny Van Heusden

“…Findings will be disseminated at conferences, through peer-reviewed manuscripts and via social media.Trial registration number ISRCTN10196901.…”
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Parasitic contamination of lettuce: comparison between establishments located in areas with high and low economic values by Gustavo Trentini Barancelli, Larissa Kochenborger, Fernanda Gracieli Machado Brum, Fabiana Tonial, Cassiano Mateus Forcelini

“…Lettuce (Lactuca sativa) is a widespread vegetable for human alimentation. Some systematic reviews showed parasitic contamination of lettuce in Brazil. …”
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Renal Dysfunction and Recovery following Initial Treatment of Newly Diagnosed Multiple Myeloma by Benjamin A. Derman, Jochen Reiser, Sanjib Basu, Agne Paner

“…A retrospective chart review was conducted of 690 patients with NDMM at Rush University Medical Center from 2005 to 2016. 118 patients (59 AA and 59 non-AA) with NDMM and an estimated glomerular filtration rate (eGFR) < 90 mL/min/1.73 m2 at the time of diagnosis were identified and analyzed. …”
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Analysis and synthesis of images of environmentally oriented innovative technologies of construction production by V. I. Telichenko, A. A. Lapidus, M. Yu. Slesarev

“…The subject of the study — verbal and graphic images of future breakthrough technologies of environmentally oriented construction production is confirmed.Conclusions. The review of images of breakthrough technologies of construction production showed the possibility of integrating live and artificial intelligence with appropriate terminological and methodological elaboration of databases and information logistics algorithms for automated generation of new technological inventions. …”
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Non-Invasive Biomarkers and Breath Tests for Diagnosis and Monitoring of Chronic Liver Diseases by Pasawat Boon-yasidhi, Wikrom Karnsakul

“…However, biopsy’s invasiveness, associated risks, and sampling variability indicate the need for reliable, noninvasive alternatives. This review examines the utility of noninvasive tests (NITs) in assessing liver disease severity, progression, and therapeutic response in patients with CLD. …”
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Diagnostic cholangioscopy for surgical planning of extrahepatic cholangiocarcinoma by Min Je Sung, Suk Pyo Shin, Chang-Il Kwon, Incheon Kang, Sung Hwan Lee, Seok Jeong Yang, Beodeul Kang, Hong Jae Chon, Gwangil Kim, Chansik An, Kwang Hyun Ko

“…The aim of this study was to evaluate the role of SOC in surgical planning for extrahepatic CCC. We reviewed the consecutive data of patients who received nab-paclitaxel plus gemcitabine-cisplatin for the management of extrahepatic CCC and underwent preoperative evaluations between June 2020 and August 2022. …”
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Intravenous Iron Repletion Does Not Significantly Decrease Platelet Counts in CKD Patients with Iron Deficiency Anemia by Neville R. Dossabhoy, Rebecca Gascoyne, Steven Turley

“…We conducted a retrospective chart review, including all patients with CKD and IDA who were treated with iron dextran total dose infusion (TDI) between 2002 and 2007. …”
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Distinguishing Reality from AI: Approaches for Detecting Synthetic Content by David Ghiurău, Daniela Elena Popescu

“…Key detection approaches reviewed include stylometric analysis, watermarking, pixel prediction techniques, dual-stream networks, machine learning models, blockchain, and hybrid approaches, highlighting their strengths and limitations, as well as their detection accuracy, independent accuracy of 80% for stylometric analysis and up to 92% using multiple modalities in hybrid approaches. …”
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Prognostic Factors on the Graft-versus-Host Disease-Free and Relapse-Free Survival after Adult Allogeneic Hematopoietic Stem Cell Transplantation by Yao-Chung Liu, Sheng-Hsuan Chien, Nai-Wen Fan, Ming-Hung Hu, Jyh-Pyng Gau, Chia-Jen Liu, Yuan-Bin Yu, Liang-Tsai Hsiao, Tzeon-Jye Chiou, Cheng-Hwai Tzeng, Po-Min Chen, Jin-Hwang Liu

“…In this regard, studies attempting to identify the prognostic factors of GRFS are quite scarce. Thus, we reviewed 377 adult patients undergoing allogeneic HSCT between 2003 and 2013. …”
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