Qualitative study exploring the views and perceptions of parents/carers of young children with CF regarding the introduction of CFTR modulator therapy (The REVEAL study; PaRents pE... by Kevin W Southern, Sioned Haf Davies, Faye Wade, Heather Fogg, Adam Walsh

“…The data were analysed using thematic analysis to identify key themes.Results Three reviewers identified four main themes: (1) The ‘roller coaster’ of parental emotions: Shock, hope, uncertainty and anticipation, (2) The dark side of the unknown, side effects and burden of decision making, (3) The value of simple pleasures in a life with CF; treatment burden, normality, future, family life and (4) Reforming clinical care in the new era of CF care; support, communication and the future.Conclusion Parents experience a range of emotions from the day of diagnosis. …”
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Evaluation of the longitudinal deformation of left ventricle and its changes in myocardial infarction and coronary heart disease with obstructive coronary artery lesions by N.V. Tytarenko, M.P. Kopytsya, I.V. Rodionova, A.V. Kobets

“…The review provides data on a new method of ultrasound diagnostics – speckle tracking echocardiography in the diagnosis of myocardial infarction and coronary heart disease with obstructive coronary artery lesions, the advantages of the global longitudinal strain (GLS) compared to the existing echocardiographic indicators of global systolic and segmental systolic function. …”
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BNPL in the Consumerism World: About the Excessive Debt Trap by Bartosz Bagniewski, Jakub Kubiczek, Zuzanna Żuchowska

“…The study relies on secondary data obtained through a thematic literature review, encompassing scientific publications and industry reports. …”
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Melanocortin Peptide Therapy for the Treatment of Arthritic Pathologies by S. J. Getting, M. Kaneva, Y. Bhadresa, D. Renshaw, Giovanna Leoni, H. B. Patel, M. J. P. Kerrigan, I. C. Locke

“…Arthritic pathologies are a major cause of morbidity within the western world, with rheumatoid arthritis affecting approximately 1% of adults. This review highlights the therapeutic potential of naturally occurring hormones and their peptides, in both arthritic models of disease and patients. …”
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An annotated high-content fluorescence microscopy dataset with EGFP-Galectin-3-stained cells and manually labelled outlineszenodo by Salma Kazemi Rashed, Malou Arvidsson, Rafsan Ahmed, Sonja Aits

“…Outlines were labelled by three annotators, who had high inter-annotator agreement between them and with a biomedical expert, who labelled some of the objects for comparison and reviewed a subset of the labels, making minor corrections as needed.The dataset comprises over 2200 annotated cell objects in total, making it sufficient in size to train high-performing neural networks for instance or semantic segmentation. …”
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Versatility of the Anterolateral Thigh Flap for Abdominal Wall Reconstruction by Nadine E. Pedrazzi, MD, Riccardo Schweizer, MD, Holger J. Klein, MD, Stephan Steiner, MD, René Vonlanthen, MD, Thomas Hermanns, MD, Didier Schneiter, MD, Pietro Giovanoli, MD, Jan A. Plock, MD

“…Charts of patients with complex abdominal wall defects who underwent a reconstruction with an ALT flap at the University Hospital of Zurich (2018–2020) were reviewed retrospectively. Patient characteristics and ALT flaps used were analyzed in detail. …”
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The work of return to work. Challenges of returning to work when you have chronic pain: a meta-ethnography by Martin Underwood, Mary Grant, Kate Seers, Robert Froud, Joanne O-Beirne-Elliman

“…Aims To understand obstacles to returning to work, as perceived by people with chronic non-malignant pain and as perceived by employers, and to develop a conceptual model.Design Synthesis of qualitative research using meta-ethnography.Data sources Eleven bibliographic databases from inception to April 2017 supplemented by citation tracking.Review methods We used the methods of meta-ethnography. …”
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Application of Infrared Spectroscopy for Functional Compounds Evaluation in Olive Oil: A Current Snapshot by Sarfaraz Ahmed Mahesar, Massimo Lucarini, Alessandra Durazzo, Antonello Santini, Anja I. Lampe, Johannes Kiefer

“…., based on chromatography and mass spectrometry. Indeed, the present review focuses on the application of infrared spectroscopy for functional compounds evaluation in olive oil.…”
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Risk of Posterior Capsular Rupture during Phacoemulsification in Patients with the History of Anti-VEGF Intravitreal Injections: Results from the Pan-American Collaborative Retina... by Raul Velez-Montoya, Idaira Sanchez-Santos, Mauricio Galvan-Chavez, Lihteh Wu, J. Fernando Arevalo, María H. Berrocal, Arturo A. Alezzandrini, Marta S. Figueroa, Roberto Gallego-Pinazo, Rosa Dolz-Marco, Clara Martinez-Rubio, Roberto Gonzalez-Salinas

“…Methods. This study reviewed the medical records of 11,129 patients from 7 different hospitals in 5 countries. …”
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Sevelamer Carbonate Crystal-Induced Colitis by T. Lai, A. Frugoli, B. Barrows, M. Salehpour

“…Colonoscopy demonstrated nearly obstructing lesions worrisome for colonic ischemia or inflammatory bowel disease. Pathological review of histology demonstrated ragged colonic mucosa with ulcerative debris and nonpolarizing crystalline material at the sites of ulceration, morphologically consistent with the phosphate binder, sevelamer carbonate. …”
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The biogenesis, regulation and functions of transitive siRNA in plants by Tan Huijun, Liu Yuelin, Guo Hongwei

“…Transitive siRNAs are produced in diverse subcellular locations and structures under the control of various mechanisms, highlighting the intricacies of their biogenesis and functions. In this review, we discuss recent advances in understanding the molecular events of transitive siRNA biogenesis and its regulation, with a particular focus on factors involved in RDR recruitment. …”
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Solid-Pseudopapillary Tumor of the Pancreas: A Single Center Experience by Valentina Beltrame, Gioia Pozza, Enrico Dalla Bona, Alberto Fantin, Michele Valmasoni, Cosimo Sperti

“…Aim of this study was to review the institutional experience of solid-pseudopapillary tumors of the pancreas with particular attention to the problems of preoperative diagnosis and treatment. …”
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Low-carbon ammonia-based fuel for maritime transport by A.A. Levikhin, A.A. Boryaev

“…The review examines decarbonized ammonia as a promising fuel for marine transportation. …”
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PHILOSOPHY OF WAR AND PEACE: IN SEARCH OF NEW EUROPEAN SECURITY STRATEGY by O. O. Bazaluk, D. B. Svyrydenko

“…It is true, that Europe has a strategy of overcoming the possible challenges, but it has sense to review ones strategy abilities to be effective at the face of new manifestations of aggression. …”
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Clinical Course and Nutritional Management of Propionic and Methylmalonic Acidemias by Amira Mobarak, Heba Dawoud, Hanaa Nofal, Amr Zoair

“…This is a retrospective review of 20 Egyptian patients diagnosed with PA (n = 10) and MMA (n = 10) in the years 2014–2018. …”
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Determinants of Caregiver Burden in Stroke Survivors who Underwent Decompressive Craniectomy by Karnam Anand, Sai Sirisha, Sanjana Putta, Sudhindra Vooturi, Manas Panigrahi, Sita Jayalakshmi, Subhash Kaul

“…Among caregivers, 58% and 16% reported to be always and frequently burdened, respectively; 33.3% of caregivers considered a retrospective review of consent for DC. A higher mRS score was associated with more burden. …”
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Correlation between Galectin-3 and Adverse Outcomes in Myocardial Infarction Patients: A Meta-Analysis by Lei Tian, Kan Chen, Zhihua Han

“…We therefore performed a systematic review and meta-analysis on the use of galectin-3 (gal3) for assessing prognosis of AMI patients. …”
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The role of ESRP1 in solid tumor development through the regulation of CD44 splicing and EMT processes by Lili Wang, Min Zhang, Lei Ke Zhao, Xiaohan Yuan, Houyu Zhao, Yanting Liu, Yinghua Ji, Ping Lu

“…Therefore, given ESRP1’s critical role in cancer development, it is gradually becoming a potential biomarker and therapeutic target. This review primarily discusses the molecular mechanisms of ESRP1 in regulating cancer metastasis, particularly its regulatory effects on CD44 splicing and the EMT process. …”
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Cytokine Storm in COVID-19 Patients, Its Impact on Organs and Potential Treatment by QTY Code-Designed Detergent-Free Chemokine Receptors by Mujahed I. Mustafa, Abdelrahman H. Abdelmoneim, Eiman M. Mahmoud, Abdelrafie M. Makhawi

“…These synthetic proteins can be injected into the body to bind the excess cytokines created by the cytokine storm; this will eventually remove the excessive cytokines and inhibit the severe symptoms caused by the COVID-19 infection. In this review, we will focus on cytokine storm in COVID-19 patients, their impact on the body organs, and the potential treatment by QTY code-designed detergent-free chemokine receptors.…”
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Pharmacological regression of atherosclerotic plaque in patients with type 2 diabetes by Loredana Bucciarelli, Daniele Andreini, Giulio Stefanini, Roberta Maria Fiorina, Marco Francone, Federica Catapano, Maria Elena Lunati, Edoardo Conte, Davide Marchetti, Paolo Fiorina

“…However, new animal models and imaging technics allowed a more complete and accurate quantitative assessment of plaque volume and are shedding new light on atherosclerosis regression. In this review, we are revisiting the existence of atherosclerosis regression in preclinical and clinical studies, with a focus on the latest mechanistic insights and on the newest pharmacological agents, particularly in patients with diabetes. …”
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