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32701
Advancing the Fight Against Cervical Cancer: The Promise of Therapeutic HPV Vaccines
Published 2025-01-01“…Unlike current prophylactic vaccines designed to prevent new infections, therapeutic vaccines aim to eradicate or treat existing HPV infections, as well as HPV-associated precancers and cancers. This review focuses on clinical studies involving therapeutic HPV vaccines for cervical cancer, specifically in three key areas: the treatment of cervical intraepithelial neoplasia; the treatment of cervical cancer in combination with or without chemotherapy, radiotherapy, or immune checkpoint inhibitors; and the role of prophylaxis following completion of treatment. …”
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32702
Meta-analysis of the efficacy and safety of secukinumab in the treatment of moderate to severe psoriasis
Published 2025-01-01“…Methods: This study conducted a comprehensive review using multiple databases, including PubMed, EMBASE, Cochrane Library, ISI Web of Knowledge, and Chinese databases such as the Biomedical Literature Database, Chinese Science and Technology Journal Full-text Database, China Journal Full-text Database, and Wanfang Database. …”
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32703
Agroecology and the limits to resilience: extending the adaptation capacity of agroecosystems to drought
Published 2025-02-01“…When climatic events are compounded by uncertainties imposed by external economic and political conditions, farmers’ abilities to overcome adversity may be reduced, emphasizing the importance of policy support, a dimension beyond the scope of this review.…”
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32704
Endoscopic Revision (StomaphyX) versus Formal Surgical Revision (Gastric Bypass) for Failed Vertical Band Gastroplasty
Published 2013-01-01“…Methods. A retrospective review was completed for patients with a previous VBG presenting with weight regain between 2003–2010. …”
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32705
A bibliometric analysis of the economic effects of using artificial intelligence and ChatGPT tools in higher education institutions
Published 2025-01-01“…For this purpose, a systematic literature review was conducted to identify and screen the scientific articles related to the topic of this study indexed in Web of Science and Scopus from 1986 to 2024. …”
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32706
Comparison of Electrocardiogram and QT Interval between Viral Hepatitis Cirrhosis and Alcoholic Cirrhosis
Published 2022-01-01“…The ECG data of patients with viral hepatitis cirrhosis and alcoholic liver cirrhosis in the outpatients and inpatients of our hospital from August 2012 to July 2018 were reviewed. The ECG data were recorded, and the ECG report was issued by ECG experts to analyze the abnormal ECG and QT interval of patients in these two groups. …”
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32707
Resveratrol-driven macrophage polarization: unveiling mechanisms and therapeutic potential
Published 2025-01-01“…Recent studies suggest that these effects are partly mediated through the regulation of macrophage polarization, wherein macrophages differentiate into pro-inflammatory M1 or anti-inflammatory M2 phenotypes. Our review highlights how resveratrol modulates macrophage polarization through various signaling pathways to achieve therapeutic effects. …”
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32708
Pharmacological Therapy of Gastroesophageal Reflux in Preterm Infants
Published 2013-01-01“…Most of the antireflux drugs, however, have not been specifically assessed in preterm infants; moreover, serious adverse effects have been noticed in association to their administration. This review mainly aims to draw the state of the art regarding the pharmacological management of GER in preterm infants, analyzing the best piecies of evidence currently available on the most prescribed anti-reflux drugs. …”
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32709
Mesothelioma and Radical Surgery 2 (MARS 2): protocol for a multicentre randomised trial comparing (extended) pleurectomy decortication versus no (extended) pleurectomy decorticati...
Published 2020-09-01“…We will submit the results for publication in a peer-reviewed journal.Trial registration numbers ISRCTN—ISRCTN44351742 and ClinicalTrials.gov—NCT02040272.…”
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32710
Woods Charred at Low Temperatures and Their Modification for the Adsorption of Cr(VI) Ions from Aqueous Solution
Published 2010-06-01“…Despite being prepared at higher temperatures and involving greater energy consumption, activated carbons always show a smaller capacity and affinity towards the adsorption of Cr(VI) ions. After a brief review regarding Cr(VI) ion contamination and treatment, the preparation of a novel biosorbent from pyrolyzed wood char for Cr(VI) ion adsorption is described. …”
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32711
Intracellular Membrane Contact Sites in Skeletal Muscle Cells
Published 2025-01-01“…This process involves the formation of dynamic membrane contact sites called Ca<sup>2</sup><sup>+</sup> Entry Units. This review explores the key processes in biogenesis and assembly of intracellular membrane contact sites as well as the membrane remodeling that occurs in response to muscle fatigue.…”
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32712
Evaluating physician concordance in interpretation of tracheobronchomalacia diagnosis and phenotyping using dynamic expiratory chest computed tomography
Published 2025-01-01“…Three specialists—a thoracic radiologist, a bronchoscopist, and a pulmonologist—reviewed identical CT scans, blinded to prior interpretations. …”
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32713
Advancements in single-cell RNA sequencing and spatial transcriptomics: transforming biomedical research
Published 2025-02-01“…Spatial transcriptomics offers valuable insights into a wide range of biomedical fields, including neurology, embryology, cancer research, immunology, and histology. This review highlights single-cell sequencing approaches, recent technological developments, associated challenges, various techniques for expression data analysis, and their applications in disciplines such as cancer research, microbiology, neuroscience, reproductive biology, and immunology. …”
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32714
Current virtual reality-based rehabilitation interventions in neuro-developmental disorders at developmental ages
Published 2025-01-01“…This mini-review examines the available papers about virtual reality (VR) as a tool for the diagnosis or therapy of neurodevelopmental disorders, focusing on Attention Deficit Hyperactivity Disorder (ADHD), Autism Spectrum Disorder (ASD), and Specific Learning Disorders (SLD). …”
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32715
Pilot Study on AI Image Analysis for Lower-Limb Reconstruction—Assessing ChatGPT-4’s Recommendations in Comparison to Board-Certified Plastic Surgeons and Resident Physicians
Published 2025-01-01“…We conducted a cross-sectional survey in Switzerland, Germany, and Austria, where 52 participants reviewed images depicting lower leg defects within fictitious patient profiles and selected the optimal reconstruction techniques. …”
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32716
Multidimensional comparative analysis of the number of students in Poland with the view to the demographic crisis and its impact on social security
Published 2024-12-01“…Material and methods The research would be based mainly on the analysis of available studies and materials enabling the review and organization of information concerning the demographic crisis, the transformation of the family model and the reorganization of the education system. …”
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32717
CHIP away at the marrow-clot connection: inflammation, clonal hematopoiesis, and thromboembolic disease
Published 2025-01-01“…However, canakinumab showed promise in a post-hoc analyses of patients with TET2-mutated CHIP, and other anti-inflammasome agents are actively under development or evaluation. In this review, we provide an overview of CHIP as a mediator of thromboembolic diseases and discuss emerging therapeutics aimed at intervening on this thrombo-inflammatory nexus.…”
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32718
Developing a data pricing framework for data exchange
Published 2025-01-01“…The data sellers fail to price optimally, and the buyers are unable to optimize their purchasing decisions, thus, reinforcing the need for a structured data pricing framework. The paper reviews literature and applies the stages as reported by Ritchie and Spencer (in: Bryman, Burgess (eds) Analysing qualitative data, Routledge, London, 1994) for applied policy research to determine the main approaches of data pricing and develop a comprehensive pricing framework. …”
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32719
THE FORMATION OF THE ENVIRONMENTAL AGENDA OF THE UNITED NATIONS GENERAL ASSEMBLY (1946-2016)
Published 2018-11-01“…However, its success would be impossible without the immense experience in addressing environmental issues gathered at the multilateral level. A review of the literature on the research topic shows that the term «environmental agenda» is not always used properly, there is a lack of empirical data to explain the «greening» of international relations. …”
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32720
Biomarkers in Nasopharyngeal Carcinoma (NPC): Clinical relevance and prognostic potential
Published 2024-09-01“…Despite these advancements, further validation in large-scale clinical trials is required to fully realize their potential. This review discusses the clinical relevance and prognostic potential of established and emerging biomarkers in NPC, emphasizing their role in refining patient management and enhancing personalized therapeutic strategies. …”
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