Central Venous Catheter-Associated Bloodstream Infections in Hemodialysis Patients: Another Patient Safety Bundle? by B Lynn Johnston, John M Conly

“…In a previous issue of The Canadian Journal of Infectious Diseases & Medical Microbiology, we reviewed the 'Safer Healthcare Now!' campaign's focus on reducing central venous catheter (CVC)-associated bloodstream infections (BSIs) as a way of improving patient safety (1). …”
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DNA repair in cancer stem cells as a factor for glioma resistance to radiotherapy by Yu. S. Makusheva, G. L. Dianov

“…The data obtained in recent years confirm the important role of CSCs in the development of tumor resistance to chemo- and radiotherapy. In this review, we present general information about classification and treatment of gliomas and consider results of research connected with the influence of radiation therapy. …”
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Development Status of Dynamic Sealing Technology and Discussion on Advanced Sealing Technologies by Yan Wang, Shuoshuo Niu, Jiahao Zhang, Cong Feng, Yutong Wang, Doudou Shen, Decai Li, Tong Li, Pengcheng Cao, Yufan Zhang

“…This paper reviews the current state of dynamic sealing technologies, examining the challenges faced by conventional sealing methods under complex working conditions, such as high temperature, high pressure, and corrosive environments. …”
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Defensive Driving: Directing HIV-1 Vaccine-Induced Humoral Immunity to the Mucosa with Chemokine Adjuvants by Ebony N. Gary, Michele A. Kutzler

“…Exploiting mucosal chemokine trafficking pathways to mobilize specific subsets of lymphocytes to mucosal tissues in the context of vaccination has improved immunogenicity and efficacy in preclinical models. This review describes the novel use of MALT chemokines as vaccine adjuvants. …”
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The Relevance of HLA Sequencing in Population Genetics Studies by Alicia Sanchez-Mazas, Diogo Meyer

“…Huge amounts of HLA sequence data will be available in the next years for different populations, with the potential to change our understanding of HLA variation in humans. In this review, we first explain how HLA sequencing allows a better assessment of the HLA diversity in human populations, taking also into account the methodological difficulties it introduces at the statistical level; secondly, we show how analyzing HLA sequence variation may improve our comprehension of population genetic relationships by facilitating the identification of demographic events that marked human evolution; finally, we discuss the interest of both HLA and genome-wide sequencing and genotyping in detecting functionally significant SNPs in the MHC region, the latter having also contributed to the makeup of the HLA molecular diversity observed today.…”
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Prevalence and association of renal disorders in Saudi adult patients with psoriasis and psoriatic arthritis: a tertiary-center retrospective cross-sectional study by Mishari Alrubaiaan, Abdullah Alhobabi, Raghad Alharthi, Saad Alsulaiman, Abdullah Altasan, Ibrahim Momen, Mohammad Almohideb

“…Medical records were reviewed for renal problems, and a multivariate logistic regression was used to investigate the relationship between psoriasis and psoriatic arthritis. …”
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Institutional Components Affecting the Internationalization of Higher Education: A Case Study on Estonia by Joamets Kristi, Vasquez Maria Claudia Solarte

“…Through a partial institutional review, it explores the challenges, opportunities, and prospects inherent to cultiva ting a well defined, principled and comprehensive internationalization approach, emphasizing the necessity of meaningful stakeholder involvement for the creation of reflective regulatory frameworks to ensure the attainment of tangible and measurable goals.…”
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Role of HNF6 in liver homeostasis and pathophysiology by Miaomiao Tian, Weizhen Gao, Shujun Ma, Huiling Cao, Yu Zhang, Fuxiang An, Jianni Qi, Zhen Yang

“…Recently, HNF6 was also found to be expressed in tissues, such as the pancreas, intestine, and lungs, where it controls their formation by regulating cell differentiation and influences their pathophysiological processes via various mechanisms. Conclusion In this review, we highlight advances in HNF6-related research concerning liver diseases and provide a summary of its potential mechanisms of action as a transcription factor in regulating downstream genes and epigenetic modifications. …”
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A 55-Year-Old Man with Stage IV Squamous Cell Carcinoma of the Right Groin after External Beam Radiation for Testicular Cancer by Christine Ibilibor, Jeremy Wells, Sravan Kavuri, Kelvin A. Moses

“…We report the case of a man who developed stage IV squamous cell carcinoma (SCC) of a condyloma after orchiectomy and adjuvant radiation for testicular cancer. We also review relevant literature available to date. A 55-year-old Caucasian man presented to the hospital with a large growth at the right groin which had grown into his right thigh preventing ambulation. …”
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Latitude-Time Total Electron Content Anomalies as Precursors to Japan's Large Earthquakes Associated with Principal Component Analysis by Jyh-Woei Lin

“…According to the results, PCA was able to discriminate clear TEC anomalies in the months when all 18 earthquakes occurred. After reviewing months when no M≥6.0 earthquakes occurred but geomagnetic storm activity was present, it is possible that the maximal principal eigenvalues PCA returned for these 18 earthquakes indicate earthquake associated TEC anomalies. …”
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PREVENTION OF INFERIORITY COMPLEX ATTITUDES ACCORDING TO THE QUR'AN by A Asnawiyah, Abd Wahid, Nurullah Amri, Muhammad Hadi Husni

“…This research is a literature review with a qualitative approach. The results of this study show that the mufassir emphasize that true strength lies in faith, solid faith is the initial key in overcoming the sense of inferiority complex, inferiority complex is the spiritual part of human beings and spiritual studies sourced from the Qur'an are the initial stages in fighting the inferiority complex. …”
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Retinopathy in Metabolic Dysfunction-Associated Steatotic Liver Disease by Myrsini Orfanidou, Stergios A. Polyzos

“…Chronic low-grade inflammation, oxidative stress, insulin resistance, and endothelial dysfunction are only some of those mechanisms contributing to disease progression and, possibly, determining the bidirectional interplay between the liver and retinal pathology. This narrative review aims to summarize data concerning the multisystemicity of MASLD, primarily focusing on its potential association with the eyes and, particularly, retinopathy. …”
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Food nutrition and toxicology targeting on specific organs in the era of single-cell sequencing by Xiaofei Wang, Xiaowen Cheng, Huiling Liu, Xiaohuan Mu, Hao Zheng

“…The ever-increasing role of scRNA-seq in dietary food research with further improvement can provide sub-cellular information and the coupling between other cellular modalities. In this review, we propose utilizing scRNA-seq to more effectively capture the subtle and complex effects of food chemicals, and how they may lead to health problems at single-cell resolution. …”
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Conducting Educational Intervention Research in General Practice: from Design to Publication by ZOU Chuan, OU Jianming, ZENG Xin, PENG Tao, ZHOU Yan, XIAO Chunyao, TAO Hongxia, CHEN Qingqi, LIN Kai

“…The purpose of this paper was to introduce the process of educational intervention research in GP from design to publication, which consists of four stages with 13 steps: constructing research questions (generating research inspiration, literature review, incorporating a theoretical/conceptual framework, refining research questions), research design (trial design, intervention, outcome evaluation), research implementation (establishing a research team, obtaining research resources, applying for ethical approval, program execution), and publication and evaluation (article writing, reflection and evaluation). …”
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Insights from in vivo preclinical cancer studies with histotripsy by Tejaswi Worlikar, Timothy Hall, Man Zhang, Mishal Mendiratta-Lala, Michael Green, Clifford S. Cho, Zhen Xu

“…Histotripsy has been recently approved by the FDA for noninvasive treatment of liver tumors. This review highlights key learnings from in vivo shock-scattering histotripsy, intrinsic threshold histotripsy, and boiling histotripsy cancer studies treating cancers of different anatomic locations and discusses the major considerations in planning in vivo histotripsy studies regarding instrumentation, tumor model, study design, treatment dose, and post-treatment tumor monitoring.…”
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Environmental Influence of Gas Flaring: Perspective from the Niger Delta Region of Nigeria by Kingsley Eghonghon Ukhurebor, Uyiosa Osagie Aigbe, Robert Birundu Onyancha, Hussain Athar, Benedict Okundaye, Paul Atagamen Aidonojie, Benita Ebindu Siloko, Ismail Hossain, Heri Septya Kusuma, Handoko Darmokoesoemo

“…Reducing GasF is a critical issue due to its ensuing complications; consequently, there is a tenacious need to measure GasF via the study of its composition, distribution, and capacity, as well as the utilization of appropriate GasF recovery/removal procedures. The present review study will, thus, attempt to assess the impacts of GasF on the environment vis-à-vis the possible nexus between GasF/CMC using the perspective of the Niger Delta region of Nigeria which is rich in PTR, with relevant information drawn from existing publications. …”
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A novel scoring system proposal to guide treatment of dogs with hepatoid gland tumors by Lorella Maniscalco, Matteo Olimpo, Lorenza Parisi, Paolo Buracco, Eugenio Mazzone, Greta Martinelli, Marina Martano, Selina Iussich, Emanuela Morello

“…Based on a retrospective review of 76 dogs with hepatoid gland tumors having clinical follow-up, the aims of this study were (1) to establish a histological grading system capable of potentially predicting prognosis and (2) to explore the role of Ki67 as a potential prognostic marker. …”
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Non-Gaussianity from Particle Production during Inflation by Neil Barnaby

“…Such models have attracted interest recently for a variety of reasons, including the possibility of slowing the motion of the inflaton on a steep potential. In this review we show that interactions between the produced particles and the inflaton condensate can lead to a qualitatively new mechanism for generating cosmological fluctuations from inflation. …”
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Purine-rich element binding protein alpha: a DNA/RNA binding protein with multiple roles in cancers by Shiyi Yu, Chengyang Jiang, Yawen Yang, Fei Cheng, Fangchen Liu, Chang Liu, Xue Gong

“…Although DNA/RNA binding proteins are hardly targeted, novel strategies have been applied to identify compounds targeting PURα and have demonstrated promising anti-tumor efficacy in the preclinical study. The present review summarizes the most recently discovered critical roles of PURα in various cancer types, providing an overview of the biomarker and therapeutic target potential of PURα for patients with cancer.…”
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Developing a Comprehensive Physical Education Curriculum in Secondary Schools: Identifying and Exploring the Key Components of Content by Yurij Vaskov

“…Methodology. A systematic review of relevant literature was conducted using publications from the Vernadskyi National Library and sources in the Google search system. …”
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