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30581
miRNAs and Melanoma: How Are They Connected?
Published 2012-01-01“…Some molecular pathways are frequently disrupted in melanoma, and miRNAs probably have a decisive role on these alterations. Therefore, this review aims to discuss new findings about miRNAs in melanoma fields, underlying epigenetic processes, and also to argue possibilities of using miRNAs in melanoma diagnosis and therapy.…”
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30582
Assessment of IL-6 Pathway Inhibition in Gastrointestinal Behçet’s Disease from Immunological and Clinical Perspectives
Published 2025-01-01“…., tumor necrosis factor α and interleukin-6 (IL-6), which could serve as a target for potential therapies. This review provides an overview of GIBD, including the diagnosis and immunopathogenesis as it is currently understood, and evaluates the emerging role of the inhibition of IL-6 (classic and trans-signaling) as an alternative treatment option for patients with GIBD. …”
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30583
Effectiveness and Cost-Benefit of an Influenza Vaccination Program for Health Care Workers
Published 1991-01-01“…This study retrospectively reviewed the effectiveness of a vaccination program for hospital workers in a large tertiary care hospital, quantified influenza-induced absenteeism, and examined the factors determining the costs and benefits of this program. …”
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30584
Applying microbial biostimulants and drought-tolerant genotypes to enhance barley growth and yield under drought stress
Published 2025-01-01“…In this context, the present review aims to underscore the importance of selecting drought-tolerant barley genotypes and utilizing bio-inoculants constructed from beneficial microorganisms as an agroecological approach to enhance barley growth and production resilience under varying environmental conditions. …”
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30585
Low Level of Innovativeness and the Middle Income Trap – Polish Case Study
Published 2014-01-01“…This is followed up by a literature-based review of the most common obstacles to innovativeness in Poland. …”
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30586
Dual-targeting CAR T cells for B-cell acute lymphoblastic leukemia and B-cell non-Hodgkin lymphoma
Published 2025-02-01“…Further, despite adding a second antigen, antigen-negative relapses have not yet been eliminated. This review summarizes the state of the art with dual-targeting CAR T cells for B-cell ALL and B-NHL, the challenges encountered, and possible next steps to overcome them.…”
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30587
Spectrum of Cytopathological Causes of Cervical Lymphadenopathy- An Experience at Sahiwal Teaching Hospital
Published 2024-12-01“…Methodology: Results of FNAC done in Sahiwal Medical College, Sahiwal were retrospectively analysed from January 2023 to December 2023 after approval from the ethical review board of the institute to determine the most common etiology of cervical lymphadenopathy in our region. …”
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30588
Intravitreal Clindamycin and Dexamethasone Combined with Systemic Oral Antitoxoplasma Therapy versus Intravitreal Therapy Alone in the Management of Toxoplasma Retinochoroiditis: A...
Published 2018-01-01“…Patients and Methods. Thirty eyes were reviewed. Two equal groups were identified (15 eyes each). …”
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30589
Role of Fractalkine/CX3CL1 and Its Receptor in the Pathogenesis of Inflammatory and Malignant Diseases with Emphasis on B Cell Malignancies
Published 2014-01-01“…Therefore the role of the CX3CL1/CX3CR1 has attracted interest as to the development of potential therapeutic approaches. Here we review the different effects of the CX3CL1/CX3CR1 axis in several inflammatory and neurodegenerative diseases and in cancer, with emphasis on human B cell lymphomas.…”
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30590
The Integration of Nanotechnology and Biology for Cell Engineering: Promises and Challenges
Published 2013-10-01“…Apart from employing different materials with distinct surface functionalities and mechanical properties, various strategies have been employed to manipulate the surface topography and chemistry of scaffolds to create a biomimetic microenvironment for effective tissue regeneration. Conclusion: This review provides information about the factors influencing tissue engineering, namely geometry, chemistry, mechanics and cells, and the emerging concepts that may well represent the future of regenerative medicine. …”
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30591
Bibliometric analysis of trends in dental management of the children with Autism Spectrum Disorder (ASD)
Published 2025-01-01“…The dimensional database field was chosen to enable the inclusion and recall of the greatest number of relevant entries. All peer-reviewed international journals published between 2004 and 2023 were included in this study. …”
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30592
Practical Steps to Design Brucellosis Preventive Interventions: An Intervention Mapping Approach
Published 2025-01-01“…In the first step, needs assessment was done through literature review, semi‐structured in‐depth interview and checklist. …”
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30593
Omental Infarction with Acute Appendicitis in an Overweight Young Female: A Rare Presentation
Published 2019-01-01“…In this report, we present a review of current literature on omental infarction and highlight the importance of imaging especially abdominal CT scan in the nonoperative diagnosis and treatment of omental infarction.…”
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30594
State-of-the-Art Techniques to Causally Link Neural Plasticity to Functional Recovery in Experimental Stroke Research
Published 2018-01-01“…However, only minor attempts have been made to connect distinct plastic remodeling processes as causative features for specific behavioral phenotypes. Here, we review current state-of the art techniques for the examination of cortical reorganization and for the manipulation of neuronal circuits as well as techniques which combine anatomical changes with molecular profiling. …”
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30595
Janus kinase inhibitors in rheumatoid arthritis-associated interstitial lung disease: where do we stand and what may be the future?
Published 2025-01-01“…The objective of this narrative review is to summarize the current evidence of the efficacy and safety of JAKis in RA-ILD management, investigating a possible emerging role for this drug class in such subset of patients. …”
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30596
Does maternal consumption of nutritive and non-nutritive sweeteners result in offspring hypertension?
Published 2025-01-01“…While NNSs provide a sweet taste without adding to sugar intake, emerging evidence suggests that maternal consumption of not only nutritive sweeteners (such as fructose) but also NNS may lead to adverse outcomes in offspring, including hypertension. This review provides an overview of the latest research connecting maternal intake of sweeteners to the long-term risk of hypertension in offspring. …”
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30597
The Textual Criticism and Structural Analysis of Noorbakhshi’s Adab-e- Insha in the Rhetoric of Prose and the Epistolary of the Safavid Era
Published 2019-02-01“…The author's perspective on this text is a rhetorical review of Epistolary Persian prose. There are six manuscripts from this work. …”
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30598
Physical Activity Protects the Human Brain against Metabolic Stress Induced by a Postprandial and Chronic Inflammation
Published 2015-01-01“…Given that even minor increases in chronic inflammation reduce brain volume in otherwise healthy individuals, the bidirectional relationship between inflammation and sedentary behaviour may explain why humans have lost brain volume in the last 30,000 years and also intelligence in the last 30 years. We review evidence that lack of physical activity induces chronic low-grade inflammation and, consequently, an energy conflict between the selfish immune system and the selfish brain. …”
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30599
Analytic Models of Brown Dwarfs and the Substellar Mass Limit
Published 2016-01-01“…We give an exact expression for the pressure of an ideal nonrelativistic Fermi gas at a finite temperature, therefore allowing for nonzero values of the degeneracy parameter. We review the derivation of surface luminosity using an entropy matching condition and the first-order phase transition between the molecular hydrogen in the outer envelope and the partially ionized hydrogen in the inner region. …”
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30600
Neuroinflammation and Oxidative Stress in Diabetic Neuropathy: Futuristic Strategies Based on These Targets
Published 2014-01-01“…These all culminate in the production of proinflammatory cytokines which are responsible for nerve tissue damage and debilitating neuropathies. This review focuses on the relationship between oxidative stress and neuroinflammation in the development and progression of diabetic neuropathy.…”
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