Down but Not Out: The Consequences of Pretangle Tau in the Locus Coeruleus by Termpanit Chalermpalanupap, David Weinshenker, Jacki M. Rorabaugh

“…Recent evidence suggests that LC neurons accumulate aberrant tau species for decades before frank LC cell body degeneration occurs in AD, suggesting that a therapeutic window exists. In this review, we combine the literature on how pathogenic tau affects forebrain neurons with the known properties and degeneration patterns of LC neurons to synthesize hypotheses on hyperphosphorylated tau-induced dysfunction of LC neurons and the prion-like spread of pretangle tau from the LC to the forebrain. …”
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Exercise as an Adjuvant Therapy for Hematopoietic Stem Cell Mobilization by Russell Emmons, Grace M. Niemiro, Michael De Lisio

“…Thus, a deeper investigation of the mechanisms responsible for exercise-induced HSPC mobilization and the factors responsible for removal of HSPCs from circulation following exercise is warranted. The present review will describe current research on exercise and HSPC mobilization, outline the potential mechanisms responsible for exercise-induced HSPC mobilization, and highlight potential sites for HSPC homing following exercise. …”
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Exosomes in Human Immunodeficiency Virus Type I Pathogenesis: Threat or Opportunity? by Sin-Yeang Teow, Alif Che Nordin, Syed A. Ali, Alan Soo-Beng Khoo

“…Accumulative findings suggested that the cellular origin of exosomes may define their effects towards HIV-1. This review summarizes the two distinctive roles of exosomes in regulating HIV pathogenesis. …”
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Potential dyes from edible mushrooms for human health by Krisyanti Budipramana, Ratih Ratih, Yanatra Budi Pramana

“…The method used in this review was to explore the literatures that discus dyes or pigments from macro fungi or mushrooms. …”
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Coherent Optics for Passive Optical Networks: Flexible Access, Rapid Burst Detection, and Simplified Structure by Guangying Yang, Yixiao Zhu, Ziheng Zhang, Lina Man, Xiatao Huang, Xingang Huang, Weisheng Hu

“…This paper provides a comprehensive review of the development of coherent PONs, particularly in aspects of preamble design for burst-mode detection in upstream scenarios, the design of flexible rate PONs in downstream scenarios, and solutions for reducing hardware complexity at the ONU side.…”
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Intestinal organoids: The path towards clinical application by Hady Yuki Sugihara, Ryuichi Okamoto, Tomohiro Mizutani

“…Despite significant contributions to basic research, challenges remain to develop intestinal organoids into clinical tools for diagnosis, prognosis, and therapy. In this review, we outline the current state of translational research involving adult stem cell and pluripotent stem cell derived intestinal organoids, highlighting the advances and limitations in disease modeling, drug-screening, personalized medicine, and stem cell therapy. …”
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Hyper-Heuristics and Scheduling Problems: Strategies, Application Areas, and Performance Metrics by Alonso Vela, Gerardo Humberto Valencia-Rivera, Jorge M. Cruz-Duarte, Jose Carlos Ortiz-Bayliss, Ivan Amaya

“…This work presents hyper-heuristic applications for scheduling problems, analyzing 215 peer-reviewed publications over the last decade. We categorize and examine the prevailing strategies and configurations of hyper-heuristics, mainly focusing on their application across diverse scheduling scenarios such as job shop, flow shop, timetabling, and project scheduling. …”
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Autophagy in brain tumors: molecular mechanisms, challenges, and therapeutic opportunities by Jiarui Zhang, Jinan Zhang, Chen Yang

“…Hence, having knowledge of the role of molecular processes in the advancement of brain tumors is enlightening, and the current review specifically examines the role of autophagy. …”
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Microlipophagy from Simple to Complex Eukaryotes by Ravinder Kumar, Colin Arrowood, Micah B. Schott, Taras Y. Nazarko

“…Macrolipophagy is the most studied and better understood at the molecular level, while our understanding of microlipophagy is very sparse. This review will discuss microlipophagy from the perspective of its conservation in eukaryotes and its importance in diseases. …”
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Population aging: a look from nursing practice based on the Nola J. Pender model by María de los Ángeles Villegas Dorticós, Zenia Tamara Sánchez García, Omayda Urbina Laza, Noel Alberto Pardillo Mustelier, Jacquelin Cordero Odery, Maydelis Gómez Valdivia

“…Population aging is not an exclusive phenomenon of modern society; it has been present in all social development stages and has always been of interest to philosophy, art and medicine. A bibliographical review is presented for evaluating the Nola J. Pender model application in health promotion, and its applicability from its theoretical vision in the community nursing practice in aging population. …”
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Preventing Long-Term Risk of Obesity for Two Generations: Prenatal Physical Activity Is Part of the Puzzle by Stephanie-May Ruchat, Michelle F. Mottola

“…Nineteen studies were included in this review: 13 interventions combining physical activity, nutrition, and GWG counselling and 6 interventions including physical activity alone. …”
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Cell-Based Strategies for Meniscus Tissue Engineering by Wei Niu, Weimin Guo, Shufeng Han, Yun Zhu, Shuyun Liu, Quanyi Guo

“…On the other side, cell self-assembling strategies without any scaffolds may be a better way to build a bionic meniscus. In this review, we primarily discuss cell seeds for meniscus tissue engineering and their application strategies. …”
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Relationship between Zinc (Zn2+) and Glutamate Receptors in the Processes Underlying Neurodegeneration by Bartłomiej Pochwat, Gabriel Nowak, Bernadeta Szewczyk

“…However, the precise interaction between Zn2+ regulative function and the glutamate system is still not fully understood. This review describes the relationship between Zn2+ and glutamate dependent signaling pathways under selected pathological central nervous system (CNS) conditions.…”
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A Survey on Event Tracking in Social Media Data Streams by Zixuan Han, Leilei Shi, Lu Liu, Liang Jiang, Jiawei Fang, Fanyuan Lin, Jinjuan Zhang, John Panneerselvam, Nick Antonopoulos

“…In this regard, this paper presents an in-depth comprehensive review of the concept and methods involved in ED and tracking in social networks. …”
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Interplay of swine acute diarrhoea syndrome coronavirus and the host intrinsic and innate immunity by Fei Zhao, Xiao Cong, Xiaobo Huang, Yi Zheng, Qin Zhao, Yiping Wen, Rui Wu, Senyan Du, Sanjie Cao, Feng Cong, Yiping Wang

“…Understanding of the mutual relationship between SADS-CoV infection and host immunity is crucial for the development of novel vaccines and drugs against SADS-CoV. Here, we review recent advancements in our understanding of the interplay between SADS-CoV infection and the host intrinsic and innate immunity. …”
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Ganglioneuroma of the External Auditory Canal and Middle Ear by Hesham Saleh Almofada, Michael Steven Timms, M. Anas Dababo

“…After the literature review and to our knowledge, this is the first reported case of its kind. …”
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Differential Diagnosis of Parotid Lipoma in a Breast Ca Patient by Melda Misirlioglu, Yagmur Yilmaz Akyil, Mehmet Zahit Adisen, Alime Okkesim

“…Patient was placed on six-month periodic recall. This article reviews the radiographic appearance and differential diagnoses of lipoma in this rare location.…”
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Development of Interactive Learning Media Using Google Sites for Thermochemistry Courses by Restika Pamungkasih, Erlina Erlina, Ira Lestari, Tulus Junanto, Maria Ulfah, Dinna Nina Mohd Nizam

“…Validation was conducted on material and media aspects, each reviewed by two validators. Data collection instruments included questionnaires for validation and student responses, involving 32 second-year Chemistry Education students who had previously studied thermochemistry concepts. …”
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Are Onconeural Antibodies a Clinical Phenomenology in Paraneoplastic Limbic Encephalitis? by Hongliang Zhang, Chunkui Zhou, Limin Wu, Fengming Ni, Jie Zhu, Tao Jin

“…The clinical importance of these conditions lies in their frequent response to immunotherapies and, less commonly, their association with distinctive tumors. This review provides an overview on the pathogenesis and diagnosis of PNS, with emphasis on the role of antibodies in limbic encephalitis.…”
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Mononuclear Aluminum–Fluoride Ions, AlF<i>_x</i>^(+/−)—Study of Plausible Frameworks of Complexes with Biomolecules and Their In Vitro Toxicity by Anja Pavlovič, Larisa Janžič, Lucija Sršen, Andreja Nataša Kopitar, Kathleen F. Edwards, Joel F. Liebman, Maja Ponikvar-Svet

“…Of particular concern are aluminum–fluoride complexes (AlF<i>_x</i>), which are able to mimic the natural isostructural phosphate group and influence the activity of numerous essential phosphoryl transferases. Our review of salts of ionic AlF<i>_x</i> species, which plausibly form the framework of complexes with biomolecules, revealed that the octahedral configuration of aluminum in the active site of the enzyme is preferred over the trigonal-bipyramidal structure. …”
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