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29581
The Impact of Antidepressants on Gut Microbiome and Depression Management
Published 2024-07-01“…Antidepressants can alter gut motility, secretion, and microbiota composition, which in turn can influence mood and mental health. This review aims to provide insights into the impact of antidepressants on gut health and their implications for depression treatment. …”
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29582
T Cell/Histiocyte-Rich Large B Cell Lymphoma of the Thymus: A Diagnostic Pitfall
Published 2016-01-01“…A year later she developed multiple enlarged lymph nodes and pulmonary nodules. Consultant review of the excised mediastinal mass showed scattered large atypical cells that were CD20+ and PAX-5+ and negative for pan-cytokeratin, AE1, and AE3, compatible with THRLBCL and excluding thymoma. …”
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29583
Neural Plasticity and Proliferation in the Generation of Antidepressant Effects: Hippocampal Implication
Published 2013-01-01“…The neurotrophic/plasticity hypothesis of depression, proposed more than a decade ago, is now supported by multiple basic and clinical studies focused on the role of intracellular-signalling cascades that govern neural proliferation and plasticity. Herein, we review the state-of-the-art of the changes in these signalling pathways which appear to underlie both depressive disorders and antidepressant actions. …”
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29584
Exploring the Role of AI-Based Conversational Agents for Collaborative Learning of English as a Foreign Language
Published 2023-12-01“…We present a literature review addressing the main objective of this paper, i.e., the exploration of the productive and unproductive uses of ChatGPT for CL in the EFL context. …”
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29585
Glia and TRPM2 Channels in Plasticity of Central Nervous System and Alzheimer’s Diseases
Published 2016-01-01“…These results potentially point TRPM2 channel to be involved in AD through glial cells. This review summarizes recent advances in studying the contribution of TRPM2 in health and in AD pathology, with a focus on contributions via glia cells.…”
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29586
From homogeneous metric spaces to Lie groups
Published 2024-11-01“…We study homogeneous metric spaces, by which we mean connected, locally compact metric spaces whose isometry group acts transitively.After a review of a number of classical results, we use the Gleason–Iwasawa–Montgomery–Yamabe–Zippin structure theory to show that for all positive $ \epsilon $, each such space is $ (1,\epsilon ) $-quasi-isometric to a connected metric Lie group (metrized with a left-invariant distance that is not necessarily Riemannian).Next, we develop the structure theory of Lie groups to show that every homogeneous metric manifold is homeomorphically roughly isometric to a quotient space of a connected amenable Lie group, and roughly isometric to a simply connected solvable metric Lie group.Third, we investigate solvable metric Lie groups in more detail, and expound on and extend work of Gordon and Wilson [31, 32] and Jablonski [44] on these, showing, for instance, that connected solvable Lie groups may be made isometric if and only if they have the same real-shadow.Finally, we show that homogeneous metric spaces that admit a metric dilation are all metric Lie groups with an automorphic dilation.…”
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29587
Clinical and economic burden of varicella in pediatric patients hospitalized in four institutions in Guatemala.
Published 2025-01-01“…This study describes the use of hospital resources, costs of care, clinical and demographic characteristics, and complications in children with varicella. A retrospective review of medical records from patients admitted in four public institutions in Guatemala between January 2015 and December 2019, with diagnosis of varicella was performed. …”
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29588
Prospect of Human Pluripotent Stem Cell-Derived Neural Crest Stem Cells in Clinical Application
Published 2016-01-01“…In addition, hESC/hiPSC-derived NCSCs with the capability of differentiating to various cell types are highly promising for clinical organ repair and regeneration. In this review, we first discuss NCSC generation methods from human pluripotent stem cells and differentiation mechanism of NCSCs. …”
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29589
Paediatric Inflammatory Bowel Disease: A Mechanistic Approach to Investigate Exclusive Enteral Nutrition Treatment
Published 2014-01-01“…Despite this, the mechanisms through which EEN induces disease remission are unknown and remain hypothetical. This review will discuss recent research into EEN both describing clinical features of EEN therapy and discussing the most up-to-date understanding of the mechanisms through which EEN may be reducing intestinal inflammation and inducing disease remission.…”
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29590
Multiscale deformable registration of noisy medical images
Published 2007-12-01“…Vese's, ''Amultiscale image representation using hierarchical (BV,L2) decompositions''(Multiscale Modeling and Simulations, 2 (2004): 4, pp. 554-579) is reviewed,and multiscale image registration algorithms are developed based on the mul-tiscale decomposition. …”
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29591
HBV cccDNA: The Molecular Reservoir of Hepatitis B Persistence and Challenges to Achieve Viral Eradication
Published 2025-01-01“…By targeting steps such as cccDNA formation, capsid assembly, or particle secretion, researchers continue to seek ways to interfere with HBV replication and to reduce its persistence, ultimately to eradicate HBV as a global health problem. This review provides an overview of what is currently known about cccDNA formation and biogenesis and the ongoing efforts to target and eradicate it to cure chronic HBV infections.…”
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29592
Advanced anaplastic thyroid carcinoma with positive expression of PD-L1 response to immune checkpoint inhibitors: A case report
Published 2025-01-01“…PD-L1 expression may serve as a potential biomarker for tumor response to immune checkpoint inhibitors in ATC. Our review highlights the need for further studies investigating the role of PD-L1 status as biomarker to predict the prognosis of immunotherapy in the treatment of ATC.…”
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29593
A Fuzzy Logic Technique for the Environmental Impact Assessment of Marine Renewable Energy Power Plants
Published 2025-01-01“…We conducted a comprehensive literature review to identify the types of impacts currently being investigated, assessed, and monitored in existing marine energy conversion projects. …”
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29594
The Iceberg Model of Change: A taxonomy differentiating approaches to change
Published 2025-01-01“…This conceptual paper, which is based on a review of the literature on change, addresses this problem by developing the ‘Iceberg Model of Change’. …”
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29595
PPAR Agonists for the Prevention and Treatment of Lung Cancer
Published 2017-01-01“…Unlike PPARα and PPARγ, whether PPARβ/δ activation is anti- or protumorigenic or even inconsequential currently remains an open question that requires additional investigation. This review of current literature emphasizes the multifaceted effects of PPAR agonists in lung cancer and discusses how they may be applied as novel therapeutic strategies for the disease.…”
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29596
Modeling Alzheimer’s Disease with Induced Pluripotent Stem Cells: Current Challenges and Future Concerns
Published 2016-01-01“…Indeed, human induced pluripotent stem cells can be differentiated into disease-relevant cell types that recapitulate the unique genome of a sporadic AD patient or family member. In this review, we will first summarize the current research findings on the genetic and pathological mechanisms of AD. …”
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29597
Cochlear Synaptopathy and Noise-Induced Hidden Hearing Loss
Published 2016-01-01“…Here, we provide a brief review to address several critical issues related to NIHHL: (1) the mechanism of noise induced synaptic damage, (2) reversibility of the synaptic damage, (3) the functional deficits as the nature of NIHHL in animal studies, (4) evidence of NIHHL in human subjects, and (5) peripheral and central contribution of NIHHL.…”
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29598
Animal Models of Diabetes-Associated Renal Injury
Published 2020-01-01“…Therefore, the type of diabetes, development of nephropathy, duration of the study, cost of maintaining and breeding, and animals’ mortality rate are important factors that might be affected by the type of DN model. In this review, we discuss the pros and cons of different rodent models of diabetes that are being used to study DN.…”
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29599
Advancements in Nanorobots: Innovating Bladder Cancer Treatments, Diagnosis and Patient Outcomes
Published 2025-01-01“…Recent advancements in in vivo trials have demonstrated significant tumor reduction in mice with bladder cancer, showing the potential of nanorobots to not only treat but also improve diagnostic capabilities in cancer therapy. This review aims to highlight the precision of nanorobots, the current knowledge on their use and their potential in clinical applications. …”
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29600
Nonfunctioning Pituitary Adenoma That Changed to a Functional Gonadotropinoma
Published 2018-01-01“…Pituitary adenomas can be classified as clinically functional or silent. Depending on the reviewed literature, these are the first or second place in frequency of the total pituitary adenomas. …”
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