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  1. 29581

    The Impact of Antidepressants on Gut Microbiome and Depression Management by Ee-Kit Tang, Ke-Yan Loo, Angel Yun-Kuan Thye, Jodi Woan-Fei Law, Loh Teng-Hern Tan, Malarvili Selvaraja, Sivakumar Thurairajasingam, Learn-Han Lee, Vengadesh Letchumanan

    Published 2024-07-01
    “…Antidepressants can alter gut motility, secretion, and microbiota composition, which in turn can influence mood and mental health. This review aims to provide insights into the impact of antidepressants on gut health and their implications for depression treatment. …”
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  2. 29582

    T Cell/Histiocyte-Rich Large B Cell Lymphoma of the Thymus: A Diagnostic Pitfall by Jie Xu, Xiaojun Wu, Vishnu Reddy

    Published 2016-01-01
    “…A year later she developed multiple enlarged lymph nodes and pulmonary nodules. Consultant review of the excised mediastinal mass showed scattered large atypical cells that were CD20+ and PAX-5+ and negative for pan-cytokeratin, AE1, and AE3, compatible with THRLBCL and excluding thymoma. …”
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  3. 29583

    Neural Plasticity and Proliferation in the Generation of Antidepressant Effects: Hippocampal Implication by Fuencisla Pilar-Cuéllar, Rebeca Vidal, Alvaro Díaz, Elena Castro, Severiano dos Anjos, Jesús Pascual-Brazo, Raquel Linge, Veronica Vargas, Helena Blanco, Beatriz Martínez-Villayandre, Ángel Pazos, Elsa M. Valdizán

    Published 2013-01-01
    “…The neurotrophic/plasticity hypothesis of depression, proposed more than a decade ago, is now supported by multiple basic and clinical studies focused on the role of intracellular-signalling cascades that govern neural proliferation and plasticity. Herein, we review the state-of-the-art of the changes in these signalling pathways which appear to underlie both depressive disorders and antidepressant actions. …”
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  4. 29584

    Exploring the Role of AI-Based Conversational Agents for Collaborative Learning of English as a Foreign Language by Ebru Pınar Elmacı Er, Armin Weinberger

    Published 2023-12-01
    “…We present a literature review addressing the main objective of this paper, i.e., the exploration of the productive and unproductive uses of ChatGPT for CL in the EFL context. …”
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  5. 29585

    Glia and TRPM2 Channels in Plasticity of Central Nervous System and Alzheimer’s Diseases by Jing Wang, Michael F. Jackson, Yu-Feng Xie

    Published 2016-01-01
    “…These results potentially point TRPM2 channel to be involved in AD through glial cells. This review summarizes recent advances in studying the contribution of TRPM2 in health and in AD pathology, with a focus on contributions via glia cells.…”
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  6. 29586

    From homogeneous metric spaces to Lie groups by Cowling, Michael G., Kivioja, Ville, Le Donne, Enrico, Nicolussi Golo, Sebastiano, Ottazzi, Alessandro

    Published 2024-11-01
    “…We study homogeneous metric spaces, by which we mean connected, locally compact metric spaces whose isometry group acts transitively.After a review of a number of classical results, we use the Gleason–Iwasawa–Montgomery–Yamabe–Zippin structure theory to show that for all positive $ \epsilon $, each such space is $ (1,\epsilon ) $-quasi-isometric to a connected metric Lie group (metrized with a left-invariant distance that is not necessarily Riemannian).Next, we develop the structure theory of Lie groups to show that every homogeneous metric manifold is homeomorphically roughly isometric to a quotient space of a connected amenable Lie group, and roughly isometric to a simply connected solvable metric Lie group.Third, we investigate solvable metric Lie groups in more detail, and expound on and extend work of Gordon and Wilson [31, 32] and Jablonski [44] on these, showing, for instance, that connected solvable Lie groups may be made isometric if and only if they have the same real-shadow.Finally, we show that homogeneous metric spaces that admit a metric dilation are all metric Lie groups with an automorphic dilation.…”
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  7. 29587

    Clinical and economic burden of varicella in pediatric patients hospitalized in four institutions in Guatemala. by Mario Melgar, Ingrid Sajmolo, André Chocó, Lidia Ortiz, Ana Gabriela Cordova, Luis Hernández, Irwing Rivera, Ashly Zuñiga, Claudia Beltrán, Sebastian Medina, Marcel Marcano-Lozada

    Published 2025-01-01
    “…This study describes the use of hospital resources, costs of care, clinical and demographic characteristics, and complications in children with varicella. A retrospective review of medical records from patients admitted in four public institutions in Guatemala between January 2015 and December 2019, with diagnosis of varicella was performed. …”
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  8. 29588

    Prospect of Human Pluripotent Stem Cell-Derived Neural Crest Stem Cells in Clinical Application by Qian Zhu, Qiqi Lu, Rong Gao, Tong Cao

    Published 2016-01-01
    “…In addition, hESC/hiPSC-derived NCSCs with the capability of differentiating to various cell types are highly promising for clinical organ repair and regeneration. In this review, we first discuss NCSC generation methods from human pluripotent stem cells and differentiation mechanism of NCSCs. …”
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  9. 29589

    Paediatric Inflammatory Bowel Disease: A Mechanistic Approach to Investigate Exclusive Enteral Nutrition Treatment by Lily Nahidi, Andrew S. Day, Daniel A. Lemberg, Steven T. Leach

    Published 2014-01-01
    “…Despite this, the mechanisms through which EEN induces disease remission are unknown and remain hypothetical. This review will discuss recent research into EEN both describing clinical features of EEN therapy and discussing the most up-to-date understanding of the mechanisms through which EEN may be reducing intestinal inflammation and inducing disease remission.…”
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  10. 29590

    Multiscale deformable registration of noisy medical images by Dana Paquin, Doron Levy, Lei Xing

    Published 2007-12-01
    “…Vese's, ''Amultiscale image representation using hierarchical (BV,L2) decompositions''(Multiscale Modeling and Simulations, 2 (2004): 4, pp. 554-579) is reviewed,and multiscale image registration algorithms are developed based on the mul-tiscale decomposition. …”
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  11. 29591

    HBV cccDNA: The Molecular Reservoir of Hepatitis B Persistence and Challenges to Achieve Viral Eradication by André Boonstra, Gulce Sari

    Published 2025-01-01
    “…By targeting steps such as cccDNA formation, capsid assembly, or particle secretion, researchers continue to seek ways to interfere with HBV replication and to reduce its persistence, ultimately to eradicate HBV as a global health problem. This review provides an overview of what is currently known about cccDNA formation and biogenesis and the ongoing efforts to target and eradicate it to cure chronic HBV infections.…”
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  12. 29592

    Advanced anaplastic thyroid carcinoma with positive expression of PD-L1 response to immune checkpoint inhibitors: A case report by Shanmin Fan, Yang Yuan, Yanfang Su, Die Sang

    Published 2025-01-01
    “…PD-L1 expression may serve as a potential biomarker for tumor response to immune checkpoint inhibitors in ATC. Our review highlights the need for further studies investigating the role of PD-L1 status as biomarker to predict the prognosis of immunotherapy in the treatment of ATC.…”
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  13. 29593

    A Fuzzy Logic Technique for the Environmental Impact Assessment of Marine Renewable Energy Power Plants by Pamela Flores, Edgar Mendoza

    Published 2025-01-01
    “…We conducted a comprehensive literature review to identify the types of impacts currently being investigated, assessed, and monitored in existing marine energy conversion projects. …”
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  14. 29594

    The Iceberg Model of Change: A taxonomy differentiating approaches to change by Christian A. Mahringer, Laura Schmiedle, Lisa Albicker, Simone Mayer

    Published 2025-01-01
    “…This conceptual paper, which is based on a review of the literature on change, addresses this problem by developing the ‘Iceberg Model of Change’. …”
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  15. 29595

    PPAR Agonists for the Prevention and Treatment of Lung Cancer by Sowmya P. Lakshmi, Aravind T. Reddy, Asoka Banno, Raju C. Reddy

    Published 2017-01-01
    “…Unlike PPARα and PPARγ, whether PPARβ/δ activation is anti- or protumorigenic or even inconsequential currently remains an open question that requires additional investigation. This review of current literature emphasizes the multifaceted effects of PPAR agonists in lung cancer and discusses how they may be applied as novel therapeutic strategies for the disease.…”
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  16. 29596

    Modeling Alzheimer’s Disease with Induced Pluripotent Stem Cells: Current Challenges and Future Concerns by Weiwei Zhang, Bin Jiao, Miaojin Zhou, Tao Zhou, Lu Shen

    Published 2016-01-01
    “…Indeed, human induced pluripotent stem cells can be differentiated into disease-relevant cell types that recapitulate the unique genome of a sporadic AD patient or family member. In this review, we will first summarize the current research findings on the genetic and pathological mechanisms of AD. …”
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  17. 29597

    Cochlear Synaptopathy and Noise-Induced Hidden Hearing Loss by Lijuan Shi, Ying Chang, Xiaowei Li, Steve Aiken, Lijie Liu, Jian Wang

    Published 2016-01-01
    “…Here, we provide a brief review to address several critical issues related to NIHHL: (1) the mechanism of noise induced synaptic damage, (2) reversibility of the synaptic damage, (3) the functional deficits as the nature of NIHHL in animal studies, (4) evidence of NIHHL in human subjects, and (5) peripheral and central contribution of NIHHL.…”
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  18. 29598

    Animal Models of Diabetes-Associated Renal Injury by Zahra Samadi Noshahr, Hossein Salmani, Abolfazl Khajavi Rad, Amirhossein Sahebkar

    Published 2020-01-01
    “…Therefore, the type of diabetes, development of nephropathy, duration of the study, cost of maintaining and breeding, and animals’ mortality rate are important factors that might be affected by the type of DN model. In this review, we discuss the pros and cons of different rodent models of diabetes that are being used to study DN.…”
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  19. 29599

    Advancements in Nanorobots: Innovating Bladder Cancer Treatments, Diagnosis and Patient Outcomes by Zehra Hussain, Alyssa Di Fonzo, Hermela Merhawi, Mary Gallant, Robert Girlan, Muhammad Hasibul Hasan

    Published 2025-01-01
    “…Recent advancements in in vivo trials have demonstrated significant tumor reduction in mice with bladder cancer, showing the potential of nanorobots to not only treat but also improve diagnostic capabilities in cancer therapy. This review aims to highlight the precision of nanorobots, the current knowledge on their use and their potential in clinical applications. …”
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  20. 29600

    Nonfunctioning Pituitary Adenoma That Changed to a Functional Gonadotropinoma by Gerson Geovany Andino-Ríos, Lesly Portocarrero-Ortiz, Carlos Rojas-Guerrero, Alejandro Terrones-Lozano, Alma Ortiz-Plata, Alfredo Adolfo Reza-Albarrán

    Published 2018-01-01
    “…Pituitary adenomas can be classified as clinically functional or silent. Depending on the reviewed literature, these are the first or second place in frequency of the total pituitary adenomas. …”
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