Nanotherapeutic smart approaches for combating Alzheimer’s disease and overcoming existing obstacles: A novel eco-friendly green approach by Ahmed M. Almehdi, Doha H. Aboubaker, Rania Hamdy, Ali El-Keblawy

“…To provide an overview of the various challenges and approaches related to using nanoparticles (NPs) to combat Alzheimer's disease (AD), this introductory review article was developed.…”
Get full text

N6-Methyladenosine in RNA and DNA: An Epitranscriptomic and Epigenetic Player Implicated in Determination of Stem Cell Fate by Pengfei Ji, Xia Wang, Nina Xie, Yujing Li

“…These achievements are inspiring scientists to further uncover the epigenetic mechanisms for stem cell development and to dissect pathogenesis of the multiple diseases conferred by development aberration of the stem cells. This review article will highlight the research advances in the role of m6A methylation modifications of DNA and RNA in the regulation of stem cell and genesis of the closely related disorders. …”
Get full text

Computational thinking in the context of higher education: Analytical review by E. K. Khenner

“…The present research aims to discuss the essence of the concept of “computational thinking” and, mainly, the composition of its structural elements, methods of their formation and assessment at the level of higher education; and to compare the requirements for university students’ computational thinking and digital competencies, which have similarities and differences.Methodology and research methods. The present review article has theoretical and applied aspects. Except for several fundamentally important works of general studies, which reveal the concept of “com­putational thinking”, the author analysed mainly review articles published in the past five years in order to identify and systematise modern solutions related to the purpose of the work.Results and scientific novelty. …”
Get full text

Oral Complications in Hematopoietic Stem Cell Recipients: The Role of Inflammation by T. M. Haverman, J. E. Raber-Durlacher, W. M. H. Rademacher, S. Vokurka, J. B. Epstein, C. Huisman, M. D. Hazenberg, J. J. de Soet, J. de Lange, F. R. Rozema

“…Inflammatory processes are key in the pathobiology of most oral complications in HSCT recipients. This review article will discuss frequently encountered oral complications associated with HSCT focusing on the inflammatory pathways and inflammatory mediators involved in their pathogenesis.…”
Get full text

Towards sustainable solutions: Comprehensive review of advanced porous materials for CO₂ capture, hydrogen generation, pollutant degradation, and energy application by Iltaf Khan, Anam Altaf, Samreen Sadiq, Shoaib Khan, Aftab Khan, Sohail Khan, Muhammad Humayun, Abbas Khan, Rasha A. Abumousa, Mohamed Bououdina

“…These materials are gaining attention for their remarkable characteristics, including high surface area, adjustable pore sizes, strong adsorption capacity, stability under various conditions, effective catalytic properties, and good electrical conductivity, making them useful across a range of applications. This review article highlights the various types, structures, and synthesis methods of POPs, MOFs, HOFs, COFs, zeolites, and PAFs, in addition to their important applications such as hydrogen generation, gas sensing, CO2 conversion, pollutant degradation, CO2 capture, hydrogen evolution/oxygen evolution reactions, and batteries. …”
Get full text

Phenolic Compounds from Apples: Reviewing their Occurrence, Absorption, Bioavailability, Processing, and Antioxidant Activity – a Review by Małgorzata Starowicz, Bohdan Achrem–Achremowicz, Mariusz K. Piskuła, Henryk Zieliński

“…Apples are popular among consumers and are known as a rich source of vitamins, minerals, and biologically active compounds. In this review article, we have focused on their phenolic compounds. …”
Get full text

Prevalence of Malaria among Adults in Ethiopia: A Systematic Review and Meta-Analysis by Fasil Adugna Kendie, Tamirat Hailegebriel W/kiros, Endalkachew Nibret Semegn, Melaku Wale Ferede

“…Malaria adversely affects the health of the peoples as well as the economic development of many developing countries including Ethiopia. Methods. This review article was reported according to PRISMA guidelines. …”
Get full text

Exploring advanced nanostructures and functional materials for efficient hydrogen storage: a theoretical investigation on mechanisms, adsorption process, and future directions by Gourhari Jana, Pratim Kumar Chattaraj

“…Its practical applications face challenges related to safe, efficient storage and release systems. This review article investigates advanced nanostructured materials for hydrogen storage, including metal acetylide and cyanide complexes, B,N-doped γ-graphyne nanotubes (γ-GNT), lithium-phosphide double helices, and Ni-decorated carbon-based clusters. …”
Get full text

Crosstalk between Tumor-Infiltrating Immune Cells and Cancer-Associated Fibroblasts in Tumor Growth and Immunosuppression of Breast Cancer by Jarupa Soongsathitanon, Pranisa Jamjuntra, Nuttavut Sumransub, Supaporn Yangngam, Marjorie De la Fuente, Glauben Landskron, Peti Thuwajit, Marcela A. Hermoso, Chanitra Thuwajit

“…The immune cells including tumor-infiltrating lymphocytes (TILs) (cytotoxic T cells (CTLs), regulatory T cells (Tregs), and helper T cell (Th)), monocyte-infiltrating cells (MICs), myeloid-derived suppressor cells (MDSCs), mast cells (MCs), and natural killer cells (NKs) play an important part in the immunological balance, fluctuating TME between protumoral and antitumoral responses. In this review article, we have summarized the impact of these immunological players together with CAF secreted substances in driving BC progression. …”
Get full text

Recent advances in the extraction technology and bioactivity of lentinan by Sizhu Ren, Chunyan Xie, Hua Liu, Liyan Li, Xiaoling Han, Wenjie Chen

“…Based on a summary of the extraction methods and biological functions of lentinan, this review article concentrates on the current literature on the extraction of lentinan, its chemical composition, and medicinal mechanisms. …”
Get full text

Assessing health governance across countries: a scoping review protocol on indices and assessment tools applied globally by Kun Tang, Liyuan Zhang, Aidan Huang, Yuling Lin, Jingwen Dong, Qiwei He

“…Dissemination will include a peer-review article, policy briefs and conference presentations. …”
Get full text

Polyunsaturated Fatty Acid and S-Adenosylmethionine Supplementation in Predementia Syndromes and Alzheimer's Disease: A Review by Francesco Panza, Vincenza Frisardi, Cristiano Capurso, Alessia D'Introno, Anna M. Colacicco, Alessandra Di Palo, Bruno P. Imbimbo, Gianluigi Vendemiale, Antonio Capurso, Vincenzo Solfrizzi

“…A growing body of evidence indicates that nutritional supplements can improve cognition; however, which supplements are effective remains controversial. In this review article, we focus on dietary supplementation suggested for predementia syndromes and Alzheimers disease (AD), with particular emphasis on S-adenosylmethionine (SAM) and polyunsaturated fatty acids (PUFA). …”
Get full text

The importance of genotyping within the climate-smart plant breeding value chain – integrative tools for genetic enhancement programs by Ana Luísa Garcia-Oliveira, Rodomiro Ortiz, Fatma Sarsu, Søren K. Rasmussen, Paterne Agre, Asrat Asfaw, Moctar Kante, Subhash Chander

“…Therefore, targeting specific loci using modern tools offers a precise and efficient approach. This review article aims to address how these new technologies can provide a better support to smallholder farmers.…”
Get full text

Targeting Nrf2/KEAP1 signaling pathway using bioactive compounds to combat mastitis by Muhammad Zahoor Khan, Liangliang Li, Yandong Zhan, Huang Binjiang, Xiaotong Liu, Xiyan Kou, Adnan Khan, Abdul Qadeer, Qudrat Ullah, Khalid J. Alzahrani, Tongtong Wang, Changfa Wang, Muhammad Zahoor

“…Collectively this review article aims to explore the potential of bioactive compounds in mitigating mastitis by targeting the Nrf2/KEAP1 signaling pathway.…”
Get full text

Availability and accessibility of cytotoxic medicines in the WHO model list of essential medicines for childhood cancer in low and lower-middle- income countries: a systematic revi... by Maheeka Seneviwickrama, Sashini Shehana Denagamagei, Surangi Jayakody, Sanjeeva Gunasekera, Guwani Liyanage

“…Six were based on quantitative, two on mixed-method research, and one was a review article. These studies represented 26 LLMICs from several continents (Africa, Asia, and America). …”
Get full text

Phytochemicals for mitigating the COVID-19 crisis: evidence from pre-clinical and clinical studies by Atri Das, Swarnali Khan, Syamal Roy, Shantanabha Das

“…Studying the effectiveness of such phytochemicals against COVID-19 and identifying new plant-derived molecules with antiviral properties have been a focus since the SARS-CoV-2 outbreak. This review article has documented in vitro, in vivo, and clinical studies encompassing 28 different phytochemicals belonging to various chemical groups (e.g., polyphenols, alkaloids, terpenes) that show anti-COVID-19 activity. …”
Get full text

OCT Biomarkers in Neovascular Age-Related Macular Degeneration: A Narrative Review by Cristian Metrangolo, Simone Donati, Marco Mazzola, Liviana Fontanel, Walter Messina, Giulia D’alterio, Marisa Rubino, Paolo Radice, Elias Premi, Claudio Azzolini

“…OCT technology is evolving very quickly, and new retinal biomarkers are continuously described. This up-to-date review article provides a comprehensive description on how structural OCT-based biomarkers provide a valuable tool to monitor the progression of the disease and the treatment response in nAMD patients. …”
Get full text

Implementing Internet-Delivered Cognitive Behavioral Therapy for Depression and Anxiety in Adults: Systematic Review by Daniel Duffy, Derek Richards, Garrett Hisler, Ladislav Timulak

“…A total of 40 articles spanning the case study, commentary, meta-analysis, mixed methods study, pilot randomized controlled trial, randomized controlled trial, qualitative study, quantitative study, review, and systematic review article types were identified as eligible for this mixed methods review. …”
Get full text

Astragalin: A Bioactive Phytochemical with Potential Therapeutic Activities by Ammara Riaz, Azhar Rasul, Ghulam Hussain, Muhammad Kashif Zahoor, Farhat Jabeen, Zinayyera Subhani, Tahira Younis, Muhammad Ali, Iqra Sarfraz, Zeliha Selamoglu

“…Natural products, an infinite treasure of bioactive chemical entities, persist as an inexhaustible resource for discovery of drugs. This review article intends to emphasize on one of the naturally occurring flavonoids, astragalin (kaempferol 3-glucoside), which is a bioactive constituent of various traditional medicinal plants such as Cuscuta chinensis. …”
Get full text

Solid-State Modification Strategies for Alpha-Mangostin Solubility Enhancement: A Review on Recent Progress by Nurin Syamimi Ahmad Izuren Shah, Muhammad Taher Bakhtiar, Syarifah Abd Rahim, Fatmawati Adam, Wan Hazman Danial, Mohd Rushdi Abu Bakar

“…It aims to identify the most effective SSM approaches, analyse their advantages, and provide insights for future research directions in addressing solubility challenges for poorly water-soluble compounds. Methods: This review article is based on a comprehensive analysis of the literature from databases like Scopus, Google Scholar, ScienceDirect, Springer, and PubChem, covering studies published in the past 15 years. …”
Get full text