Pathogenicity of germline VHL variants is associated with renal cell carcinoma size in von Hippel-Lindau disease by Gustavo H. Mori, Gustavo F. C. Fagundes, Lucas S. Santana, Felipe Freitas-Castro, Ana Caroline F. Afonso, Delmar M. Lourenço Jr., Maria Adelaide A. Pereira, Fabio Y. Tanno, Victor Srougi, Jose L. Chambo, Mauricio D. Cordeiro, William C. Nahas, Ana O. Hoff, Maria Candida B. V. Fragoso, Berenice B. Mendonca, Ana Claudia Latronico, Madson Q. Almeida

“…Subjects and methods: We retrospectively studied 53 consecutive patients with VHL disease and confirmed genetic diagnoses from 32 relatives. …”
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Relationship between Schlemm’s canal incision length and the results of ab interno gonioscopy-assisted transluminal suture trabeculotomy by Hirotaka Tanabe, Shunsuke Nakakura, Kazuaki Nishimura, Etsuko Terao, Yasuko Fujisawa, Yuki Nagata, Satomi Oogi, Miku Adachi, Kanae Matsuya

“…Abstract We retrospectively investigated the relationship between Schlemm’s canal incision length and the results of ab interno gonioscopy-assisted transluminal suture trabeculotomy (GATST) with/without cataract surgery in open-angle glaucoma patients at Tsukazaki Hospital from 2018–2021. …”
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Clinical application of optical and electromagnetic navigation system in CT-guided radiofrequency ablation of lung metastases by Zenan Chen, Liangliang Meng, Yueyong Xiao, Jing Zhang, Xiaobo Zhang, Yingtian Wei, Xiaofeng He, Xin Zhang, Xiao Zhang

“…Purpose To evaluate the clinical value of CT-guided radiofrequency ablation (RFA) in the diagnosis and treatment of pulmonary metastases under optical and electromagnetic navigation.Methods Data on CT-guided radiofrequency ablation treatment of 93 metastatic lung lesions in 70 patients were retrospectively analyzed. There were 46 males and 24 females with a median age of 60.0 years (16–85 years). …”
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10 Fr S-Type Plastic Pancreatic Stents in Chronic Pancreatitis Are Effective for the Treatment of Pancreatic Duct Strictures and Pancreatic Stones by Ken Ito, Naoki Okano, Seiichi Hara, Kensuke Takuma, Kensuke Yoshimoto, Susumu Iwasaki, Yui Kishimoto, Yoshinori Igarashi

“…Endoscopic pancreatic stenting for refractory pancreatic duct strictures associated with impacted pancreatic stones in chronic pancreatitis cases has yielded conflicting results. We retrospectively evaluated the efficacy of endoscopic treatment in chronic pancreatitis patients with pancreatic duct strictures. …”
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Association between Clinical Characteristics and Laboratory Findings with Outcome of Hospitalized COVID-19 Patients: A Report from Northeast Iran by Sahar Sobhani, Reihaneh Aryan, Elham Kalantari, Salman Soltani, Nafise Malek, Parisa Pirzadeh, Amir Yarahmadi, Atena Aghaee

“…Data were obtained retrospectively from medical records of 397 hospitalized COVID-19 patients between February and May 2020 in Imam Reza Hospital, northeast Iran. …”
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Effectiveness of dupilumab treatment against refractory eosinophilic chronic rhinosinusitis by Daiki Nakashima, MD, Tsuguhisa Nakayama, MD, PhD, Shunsuke Minagawa, MD, PhD, Tetsuya Adachi, MD, PhD, Chieko Mitsuyama, MD, Yoko Shida, MD, Tsuneya Nakajima, MD, PhD, Shin-ichi Haruna, MD, PhD, Yoshinori Matsuwaki, MD, PhD

“…Objectives: This study aimed to determine the effectiveness of dupilumab in ECRS with postoperative recurrence. Methods: We retrospectively enrolled 107 patients and assessed the effectiveness of dupilumab by various clinical outcomes. …”
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Crimean-Congo haemorrhagic fever virus screening among African individuals in Spain: Lessons to learn by Helena Miriam Lorenzo Juanes, Amparo López-Bernus, Belen Vicente, Montserrat Alonso-Sardón, Beatriz Rodríguez Alonso, Josue Pendones Ulerio, Pedro Fernandez Soto, Juan Luis Muñoz Bellido, Antonio Muro, Moncef Belhassen-García

“…Methodology: A seroepidemiological study was conducted among African patients referred to the University Hospital of Salamanca, Spain. Patients were retrospectively recruited from 2005 to 2023. Principal findings: We screened 485 serum samples, with a mean (±SD) age of 17 years (±9.9). …”
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Case report: Accidental aconitine poisoning caused by the inappropriate use of a type of Chinese patent medicine by Ruikai Shang, Ruikai Shang, Hongyu Liu, Qiaoxin Tian, Qiaoxin Tian, Yuru Liu, Xiangdong Jian, Xiangdong Jian, Qilu Li

“…However, improper use and overdose can easily cause acute poisoning, leading to malignant arrhythmias, cardiogenic shock, and even death.MethodsThis study retrospectively analyzed the clinical data of eight patients who were treated in our hospital from June 2023 to February 2024 after taking compound schizonepeta fumigation lotion by mistake.Case presentationWe report 8 cases of patients who took compound schizonepeta fumigation lotion by mistake. …”
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Comparison of Endocrine Profile and In Vitro Fertilization Outcome in Patients with PCOS, Ovulatory PCO, or Normal Ovaries by Yi-Ping Zhong, Ying Ying, Hai-Tao Wu, Can-Quan Zhou, Yan-Wen Xu, Qiong Wang, Jie Li, Xiao-Ting Shen, Jin Li

“…The basic clinical features and in vitro fertilization and embryo transfer outcome in patients receiving IVF or intracytoplasmic sperm injection (ICSI) were retrospectively analyzed. Results. The body mass index, basal luteinizing hormone, and testosterone levels were significantly lower in patients with ovulatory PCO compared to those in patients with PCOS. …”
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Effect and factors associated with reactivation after intravitreal conbercept or aflibercept in retinopathy of prematurity by Chunling Huang, Weikang Zou, Wenbei Ma, Jiali Li, Yichen Bai, Rong Wu, Qiqi Li, Qi Fang, Wenna Chen, Xiaohe Lu, Songfu Feng

“…Abstract Background To evaluate the effect and factors associated with the reactivation of retinopathy of prematurity (ROP) after intravitreal conbercept or aflibercept. Methods We retrospectively reviewed the medical records of 176 eyes diagnosed with ROP and treated with anti-VEGF therapy between January 2018 and September 2022. …”
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Clinical Characteristics and Visual Outcomes of Patients Hospitalized for Ocular Trauma in Shandong Province, China by Fangnan Duan, Xiunian Chen, Sai Zhang, Xiaolin Qi, Weiyun Shi, Hua Gao

“…The inpatient data of patients with eye injuries hospitalized in our institution from January 2014 to December 2018 were retrospectively reviewed, including demographic information, types of trauma, causes of injury, treatment, and initial and final visual acuities. …”
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Examining the Formalin Fixation Method for Maintaining High RNA Quality in Surgical Lung Specimens by Takashi Teishikata, Manabu Itoh, Yusuke Okamoto, Naofumi Miyahara, Chiho Nakashima, Koichiro Takahashi, Masafumi Hiratsuka, Keita Kai, Keiji Kamohara

“…Methods Sheet‐like fixation specimens (n = 15), conventional fixation specimens of the same resected lungs (n = 15), and other lung cancer specimens collected for conventional fixation and subjected to multiplex gene‐panel testing (n = 22) were retrospectively examined. RNA was extracted from each specimen. …”
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Respiratory Impairment after Early Red Cell Transfusion in Pediatric Patients with ALI/ARDS by Surender Rajasekaran, Dominic Sanfilippo, Allen Shoemaker, Scott Curtis, Sandra Zuiderveen, Akunne Ndika, Michael Stoiko, Nabil Hassan

“…The course of 34 transfused patients was retrospectively compared to 45 nontransfused control patients admitted to the PICU at Helen DeVos Children’s Hospital between January 1st 2008 and December 31st 2009. …”
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Impact of Enhanced Recovery After Surgery Protocol Compliance on Outcome After Pancreatic Surgery: Results From a Certified ERAS Center by Alina S. Ritter, MD, Thilo Welsch, MD, FACS, MBA, Freya Brodersen, MSc, Julia Auinger, MD, Parisa Moll-Khosrawi, MD, Mara R. Goetz, MD, Jan Bardenhagen, MD, Christine Nitschke, MD, Tobias Schneider, BSc, Björn Wellge, MD, Anna Suling, PhD, Faik G. Uzunoglu, MD, Asmus Heumann, MD, Felix Nickel, MD, Thilo Hackert, MD, Jakob R. Izbicki, MD

“…The datasets were retrospectively collected from a central database. The effects of individual ERAS items and compliance on morbidity and hospital stay were assessed by uni- and multivariable analyses. …”
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CD34 evaluation of microvasculature in lung adenocarcinoma and its microvascular density predicts postoperative tumor recurrence by Zijian Qiu, Jiaji Wu, Guanchao Pang, Xia Xu, Jun Lin, Pingli Wang

“…Thus, the detection of intratumoral MVD is of great significance for understanding disease progression and predicting patient prognosis.MethodsTumor tissue sections of 238 patients with lung adenocarcinoma (LUAD) who underwent radical surgery were retrospectively analyzed. Immunohistochemical (IHC) staining was carried out using a CD34 polyclonal antibody to determine intratumoral MVD, and the relationship of CD34-MVD with the clinicopathological characteristics and survival time of LUAD patients was analyzed.ResultsCD34-MVD was associated with tumor size, lymph node metastasis, tumor recurrence, and patient survival status; patients with tumor size ≤3 cm (P = 0.015), negative for lymph node metastasis (P = 0.049), no tumor recurrence (P = 0.021), and survival (P = 0.042) had higher MVD. …”
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Comparison of clinical variables and outcome of 2 natural equine herpesvirus myeloencephalopathy outbreaks induced by equine herpesvirus‐1 A2254/N752 strain in sport horses by María de laCuesta‐Torrado, Ana Velloso Alvarez, José Miguel Cárdenas‐Rebollo, Patricia Neira‐Egea, Valentina Vitale, Juan Cuervo‐Arango

“…Methods Data collected from the VTH and surveys completed by riders and horse owners were analyzed retrospectively. Results No risk factors associated with EHM development showed significant differences between the outbreaks; both outbreaks were caused by A2254/N752 strains. …”
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Long-Term Outcomes of Caustic Esophageal Stricture with Endoscopic Balloon Dilatation in Chinese Children by Lan-Lan Geng, Cui-Ping Liang, Pei-Yu Chen, Qiang Wu, Min Yang, Hui-Wen Li, Zhao-Hui Xu, Lu Ren, Hong-Li Wang, Shunxian Cheng, Wan-Fu Xu, Yang Chen, Chao Zhang, Li-Ying Liu, Ding-You Li, Si-Tang Gong

“…We aimed to evaluate the long-term outcomes of endoscopic balloon dilatation (EBD) in treating CES in children and the influencing factors associated with outcome. We retrospectively reviewed the data of all patients who had a diagnosis of CES and underwent EBD from August 1, 2005, to December 31, 2014. …”
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Total Psoas Area Predicts Complications following Radical Cystectomy by Timothy D. Lyon, Nicholas J. Farber, Leo C. Chen, Thomas W. Fuller, Benjamin J. Davies, Jeffrey R. Gingrich, Ronald L. Hrebinko, Jodi K. Maranchie, Jennifer M. Taylor, Tatum V. Tarin

“…Patients who underwent radical cystectomy at our institution from 2011 to 2012 were retrospectively identified. Total psoas area was measured on preoperative CT scans and normalized for patient height. …”
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Clinical outcomes of intravenous urography-assisted shockwave lithotripsy for radiolucent ureteral stones by Shinya Somiya, Shigeki Koterazawa, Katsuhiro Ito, Takao Haitani, Yuki Makino, Ryuichiro Arakaki, Norio Kawase, Yoshihito Higashi, Hitoshi Yamada, Toru Kanno

“…Objective: We aimed to compare the clinical outcomes of intravenous urography-assisted fluoroscopy-guided shockwave lithotripsy for radiolucent ureteral stones and standard shockwave lithotripsy for radiopaque ureteral stones. Methods: We retrospectively reviewed 734 patients with ureteral stones treated by fluoroscopy-guided shockwave lithotripsy between March 2014 and March 2021. …”
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Decrease in HBsAg After TAF Switching from Entecavir During Long-Term Treatment of Chronic Hepatitis B Virus Infection by Kazuto Tajiri, Yuka Hayashi, Aiko Murayama, Nozomu Muraishi, Masami Minemura, Ichiro Yasuda

“…Tenofovir alafenamide fumarate (TAF), a recommended NA for managing chronic HBV infection (CHB), has uncertain effects on HBsAg levels and potential adverse events when used long-term after switching from entecavir (ETV). We retrospectively evaluated 77 CHB patients, including 47 who switched from ETV to TAF with a median follow-up of 40 months post-switch and a median of 60 months of HBsAg monitoring pre-switch. …”
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