Clinical Characteristics and Prevalence of Comorbidities according to Metformin Use in Korean Patients with Type 2 Diabetes by Sang Ouk Chin, In Gyoon Ha, Sang Youl Rhee, Su Jin Jeong, Suk Chon, Sung Hoon Kim, Kyu Jeung Ahn, Sei Hyun Baik, Yongsoo Park, Moon Suk Nam, Kwan Woo Lee, Jeong Taek Woo

“…Metformin users were significantly younger and had higher and glycated hemoglobin with significantly lower rates of accompanying microvascular complications such as retinopathy, cataracts, overt proteinuria, renal insufficiency, and peripheral neuropathy than nonusers. …”
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Establishment of a metabolite diagnostic model for the risk of diabetic nephropathy in type 2 diabetic population: Based on a cross-sectional study in China by Jing-Yang Su, Yong-Jie Chen, Wei Zhang, Rui Zhang, Tong-Feng Liu, Wei-Ming Luo, Xi-Lin Yang, Zhong-Ze Fang

“…Additionally, the DN group had a higher prevalence of stroke patients (P ​< ​0.001) and diabetic retinopathy patients (P ​< ​0.001). Finally, a risk model that included citrulline, leucine, tyrosine, valine, propionylcarnitine (C3), and palmitoylcarnitine (C16) was developed. …”
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Mesenchymal stem cell‐derived exosomes mitigate amyloid β‐induced retinal toxicity: Insights from rat model and cellular studies by Amanda Qarawani, Efrat Naaman, Rony Ben‐Zvi Elimelech, Michal Harel, Shahaf Sigal‐Dror, Tali Ben‐Zur, Tamar Ziv, Daniel Offen, Shiri Zayit‐Soudry

“…The multifaceted nature of AMD pathophysiology, presumably involving diverse retinal cascades, corresponds with the complexity of Aβ‐induced retinopathy. Therefore, targeting a broad array of pathogenic processes holds promise for therapeutic intervention in AMD‐associated retinal pathology. …”
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Correlation of Vitreous Vascular Endothelial Growth Factor and Uric Acid Concentration Using Optical Coherence Tomography in Diabetic Macular Edema by Libuse Krizova, Marta Kalousova, Ales Antonin Kubena, Oldrich Chrapek, Barbora Chrapkova, Martin Sin, Tomas Zima

“…A prospective study of 29 eyes, 16 cystoid DME and nonproliferative diabetic retinopathy (DR) and 13 nondiabetic controls. Biochemical analysis of vitreous and serum samples was performed and OCT scans were graded according to central retinal thickness (CRT), cube volume (CV), cube average thickness (CAT), and serous retinal detachment (SRD). …”
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Predictors of glycemic control among type 1 pediatric diabetes patients—Northeast Ethiopia by Hiwot Adege, Gedefaw Getnet, Abyou Seyfu Ambaye, Mekuanint Terefe Kassa, Bedilu Linger Endalifer

“…The majority of the patients were female, totaling 126 (62.1%), and about 69 (34.0%) were in grades 7–10. Retinopathy, nephropathy, and diabetic ketoacidosis were commonly observed diabetic-related complications in this study. …”
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Ionized and total magnesium levels and health outcomes in patients with type 2 diabetes mellitus by Juhaina Salim Al-Maqbali, Salwa Al Harasi, Qasim Al Mamary, Henrik Falhammar, Ibrahim Al-Zakwani, Mohammed Al Za’abi, Abdullah M. Al Alawi

“…An iMg/tMg ratio above 80% was associated with elevated HbA1c levels, while ratios below 60% were associated with diabetic retinopathy and hypertension. Dysmagnesemia was common among patients with T2DM. …”
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Long term cost-effectiveness analysis of IDegLira in the treatment of type 2 diabetes patients compared to GLP-1RA added to basal insulin after IDegLira entered the national reimbu... by Dunming Xiao, Junling Weng, Lei Zhang, Chang Xing, Yan Wei, Yingyao Chen

“…The eye diseases (background, proliferative retinopathy, macular edema, and visual loss) decreased by 24.4%, 41.1%, 18.9%, and 12.2%, respectively. …”
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Past Obesity as well as Present Body Weight Status Is a Risk Factor for Diabetic Nephropathy by Shu Meguro, Yusuke Kabeya, Karin Tanaka, Toshihide Kawai, Masuomi Tomita, Takeshi Katsuki, Yoichi Oikawa, Yoshihito Atsumi, Akira Shimada, Masami Tanaka, Junichiro Irie, Yoshifumi Saisho, Hiroshi Itoh

“…In logistic regression analysis, previous obesity, as well as current obesity, was a significant risk factor for nephropathy, independent of sex, age, disease duration, hypertension, dyslipidemia, HbA1c, and diabetic retinopathy. Conclusions. Obesity in the past, as well as the present body weight status, was a risk factor for diabetic nephropathy.…”
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Risk Factors for Cognitive Impairment in Patients with Type 2 Diabetes by Lin Sun, Xue Diao, Xiaokun Gang, You Lv, Xue Zhao, Shuo Yang, Ying Gao, Guixia Wang

“…The severity of fundus retinopathy and the incidence of macrovascular disease also differed significantly among the groups (P<0.05). …”
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The Prevalence of Undiagnosed Age-Related Sight-Threatening Diseases in Self-Proclaimed Healthy Individuals by Sophie Lemmens, João Barbosa Breda, Karel Van Keer, Tine Jacobs, Ruben Van Landeghem, Patrick De Boever, Ingeborg Stalmans

“…Age-related conditions such as glaucoma, age-related macular degeneration, diabetic retinopathy, and cataract have become the major cause of visual impairment and blindness in high-income countries. …”
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Multi-omic spatial effects on high-resolution AI-derived retinal thickness by V. E. Jackson, Y. Wu, R. Bonelli, J. P. Owen, L. W. Scott, S. Farashi, Y. Kihara, M. L. Gantner, C. Egan, K. M. Williams, B. R. E. Ansell, A. Tufail, A. Y. Lee, M. Bahlo

“…The macula is disproportionately affected by high disease burden retinal disorders such as age-related macular degeneration and diabetic retinopathy, which both involve metabolic dysregulation. …”
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Efficacy and safety of faricimab for neovascular age-related macular degeneration: a systematic review and network meta-analysis by Francisco Rodríguez, Daniel Samacá-Samacá, Claudia Hernández-Castillo, Laura Prieto-Pinto, Carolina Sardi, Hugo Ocampo, Joshua Kock, Fabián Hernández

“…Outcomes included changes in visual acuity (Early Treatment of Diabetic Retinopathy Study [ETDRS] letters), anatomical changes, frequency of injections and adverse events. …”
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Suboptimal Blood Pressure Control, Associated Factors, and Choice of Antihypertensive Drugs among Type 2 Diabetic Patients at KCMC, Tanzania by Gabriel W. Mbwete, Kajiru G. Kilonzo, Elichilia R. Shao, Nyasatu G. Chamba

“…It is a risk factor for the development of diabetes as well as complications like coronary artery disease (CAD), nephropathy, retinopathy, and neuropathy. Hypertension is treatable, and the degree to which it is controlled determines the risk of development of cardiovascular diseases and other complications in a given individual patient. …”
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Flt3 Regulation in the Mononuclear Phagocyte System Promotes Ocular Neovascularization by Yushuo Gao, Yisheng Zhong, Yanji Zhu, Anna M. Demetriades, Yujuan Cai, Jikui Shen, Qing Lu, Xi Shen, Bing Xie

“…Increased Flt3 expression at the protein level was detected in retinas of oxygen-induced retinopathy (OIR) mice at P15 and P18 during retinal NV (RNV) progression. …”
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Studying red cell distribution width in Iraqi persons with type 2 diabetes mellitus in Najaf City: a case-control study by Maysam Riyadh Mohammed Hussein Alaasam, Karrar Mohammed Abbas Al-buthabhak, Ahmed Mech, Shamim Riadh Mohammed Hussein

“…People with a history of anemia, renal failure, heart disease, hypertension, thyroid disorder, pregnancy, and conditions leading to chronic inflammation, such as rheumatoid arthritis, diabetic neuropathy, diabetic retinopathy, and diabetic nephropathy, were excluded from the study. …”
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Predictive value of different baseline optical coherence tomography biomarkers for visual acuity changes in neovascular age-related macular degeneration by Hamid Riazi-Esfahani, Hooshang Faghihi, Fatemeh Bazvand, Mohammadreza Mehrabi Bahar, Hassan Khojasteh, Ahmed Husein Ahmed, Shahin Faghihi, Ali Fakhraie, Mohammad Hossein Zamani, Samin Ghasemi, Esmaeil Asadi Khameneh, Elias Khalili Pour

“…Results Among 89 eyes with nAMD, mean best-corrected visual acuity (BCVA) improved by 6 Early Treatment Diabetic Retinopathy Study (ETDRS) letters from baseline to month 3, with sustained improvement through month 12. …”
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Randomised, multicentre, placebo-controlled trial of fenofibrate for treatment of diabetic macular oedema with economic evaluation (FORTE study): study protocol for a randomised co... by Gerald Liew, Paul Mitchell, Bamini Gopinath, Helen Nguyen, Richard Kha

“…Introduction Diabetic macular oedema (DMO), a serious ocular complication of diabetic retinopathy (DR), is a leading cause of vision impairment worldwide. …”
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Association between atherogenic index of plasma and type 2 diabetic complications: a cross-sectional study by Yue-Yang Zhang, Yue-Yang Zhang, Yue-Yang Zhang, Yue-Yang Zhang, Yue-Yang Zhang, Xiao-Yu Yang, Xiao-Yu Yang, Xiao-Yu Yang, Xiao-Yu Yang, Xiao-Yu Yang, Qin Wan, Qin Wan, Qin Wan, Qin Wan, Qin Wan

“…In this study, logistic regression, restricted cubic splines, and subgroup analyses were employed to evaluate the association between the AIP and four major complications of type 2 diabetes, namely, type 2 diabetes with carotid atherosclerosis (DA), diabetic kidney disease (DKD), diabetic retinopathy (DR), and diabetic peripheral neuropathy (DPN).ResultsThe logistic regression results demonstrate that in the fully adjusted model, each SD increase in AIP correlates with an elevated risk of type 2 diabetic kidney disease (DKD), with the risk of kidney damage intensifying alongside higher AIP groupings. …”
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Factors That Influence Refractive Changes in the First Year of Myopia Development in Premature Infants by Jianbo Mao, Jimeng Lao, Chenyi Liu, Mingyuan Wu, Xueting Yu, Yirun Shao, Lin Zhu, Yiqi Chen, Lijun Shen

“…To study the development of refractive status from 36 weeks to one year of postmenstrual age and to identify factors that contribute to development of myopia, including gender, birth weight, gestational age, and retinopathy of prematurity (ROP). Methods. Premature infants underwent full cycloplegic retinoscopy at 36 weeks, 38 weeks, 40 weeks, 42 weeks, 44 weeks, 46 weeks, 48 weeks, 3 months, 6 months, 9 months, and 12 months of postmenstrual age. …”
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Development and progression association of various ophthalmic pathologies with the gut microbiome state (literature review) by G.N. Rezbaeva, A.E. Babushkin, O.I. Orenburkina, I.A. Gimranova

“…For instance, dry eye syndrome, especially chronic progressive ophthalmic pathology, such as diabetic retinopathy, glaucoma, age-related macular degeneration, etc. …”
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