Does Fundus Fluorescein Angiography Procedure Affect Ocular Pulse Amplitude? by Gökhan Pekel, Semra Acer, Ramazan Yagci, Ebru Nevin Cetin, Mehmet Can Hiraali, Hüseyin Kaya

“…Sixty eyes of 30 nonproliferative diabetic retinopathy patients (15 males, 15 females) were included in this cross-sectional case series. …”
Get full text

Risk factors for and short-term prognosis of intrauterine infection in preterm infants by Xuemei Zhao, Yue Song, Liqun Lu

“…The infants with IUI showed higher incidences of respiratory distress syndrome, bronchopulmonary dysplasia, retinopathy of prematurity, and prolonged mechanical ventilation. …”
Get full text

Case report of twins with Bardet-Biedl syndrome exhibiting a rare mutation in the TTC8 gene by Agnieszka Murawska, Kamil Możdżeń, Grzegorz Horosin, Edward Pędziwiatr, Joanna Makowska, Jakub Pośpiech, Konrad Kaleta, Dorota Drożdż, Katarzyna Zachwieja

“…Both twins presented several symptoms characteristic of BBS, such as retinopathy, visceral obesity, postaxial polydactyly, renal dysfunction, cognitive impairment, facial dysmorphia, and dental abnormalities. …”
Get full text

Adropin as an indicator of T2DM and its complications by Hu Zhang, Ning Chen

“…In this article, the underlying mechanisms of adropin for regulating obesity, T2DM and its complications including diabetic nephropathy, diabetic retinopathy, diabetic encephalopathy, diabetic vascular disease and diabetic cardiovascular disease were summarized. …”
Get full text

Development of Anti-VEGF Therapies for Intraocular Use: A Guide for Clinicians by Pearse A. Keane, Srinivas R. Sadda

“…As a result, several groups targeted this molecule as a potential mediator of retinal ischemia-induced neovascularization in disorders such as diabetic retinopathy and retinal vein occlusion. Around this time, it also became clear that increased intraocular VEGF production was not limited to ischemic retinal diseases but was also a feature of choroidal vascular diseases such as neovascular age-related macular degeneration (AMD). …”
Get full text

Differential microvascular endothelial cell responses in the retina in diabetes compared to the heart and kidneys, a spatial transcriptomic analysis. by Eric Wang, Biao Feng, Shali Chen, Zhaoliang Su, Subrata Chakrabarti

“…Endothelial cells and high glucose-induced endothelial dysfunction are the common origin of chronic diabetic complications such as retinopathy, nephropathy, and cardiomyopathy. Yet their common origins, the vascular manifestations of such complications are different. …”
Get full text

Renal affection among type 2 diabetic patients and their families by Omar T. Selim, Eglal M. Kenawy, Abdelhamed A. Abdelhafez, Mona M. Abdelmeguid

“…Results The prevalence of microvascular complications in diabetic patients and their relatives was as follows: nephropathy (27.5 and 5%, respectively), neuropathy (30 and 8.75%, respectively), and retinopathy (18.83 and 6.2%, respectively). Overall, 22.5% of the relatives had metabolic srtndrome. …”
Get full text

Optimising deep learning models for ophthalmological disorder classification by S. Vidivelli, P. Padmakumari, C. Parthiban, A. DharunBalaji, R. Manikandan, Amir H. Gandomi

“…Disorders such as hypertension, glaucoma, and diabetic retinopathy are indicated by structural alterations in the optic disc, blood vessels, fovea, and macula. …”
Get full text

The Increased Circulating Plasma Levels of Vascular Endothelial Growth Factor in Patients with Type 1 Diabetes Do Not Correlate to Metabolic Control by Kailash Singh, Stellan Sandler, Daniel Espes

“…The levels of VEGF were similar in patients with T1D and microvascular complications (microalbuminuria and retinopathy) when compared with patients without microvascular complications. …”
Get full text

The application of procyanidins in diabetes and its complications: a review of preclinical studies by Yongchuang Zhang, Mengna Li, Haoyuan Liu, Yongfu Fan, Huan Huan Liu

“…Diabetes mellitus (DM) and its various complications, including diabetic nephropathy, retinopathy, neuropathy, cardiovascular disease, and ulcers, pose significant challenges to global health. …”
Get full text

Changing consumption of resources for respiratory support and short-term outcomes in four consecutive geographical cohorts of infants born extremely preterm over 25 years since the... by Alicia J Spittle, Lex W Doyle, Peter J Anderson, Li Huang, Jeanie L Y Cheong, Alice C Burnett, Anjali Haikerwal, Merilyn Bear, Margaret Charlton, Janet Courtot, Noni Davis, Julianne Duff, Rachel Ellis, Marie Hayes, Elisha Josev, Elaine Kelly, Marion Mcdonald, Emma Mcinnes, Bronwyn Novella, Gillian Opie, Gehan Roberts, Katherine Scott, Penelope Stevens, Anne-marie Turner, Kim M Dalziel, Katherine Lee, Marissa Clark, Joy E Olsen, Rosemarie A Boland, Alice E Stewart, Leah M Hickey

“…Cystic periventricular leukomalacia reduced in incidence but retinopathy of prematurity requiring treatment increased. …”
Get full text

Combination of Anti-VEGF and Laser Photocoagulation for Diabetic Macular Edema: A Review by Laura N. Distefano, Jose Garcia-Arumi, Vicente Martinez-Castillo, Anna Boixadera

“…Thirty years ago, the Early Treatment Diabetic Retinopathy Study (ETDRS) demonstrated that focal/grid laser photocoagulation reduces moderate vision loss from DME by 50% or more; thus, macular photocoagulation became the gold standard treatment for DME. …”
Get full text

Anti-VEGF Agents for Ocular Angiogenesis and Vascular Permeability by Kenichi Kimoto, Toshiaki Kubota

“…IVB has also been reported to be effective for inducing the regression of new vessels in proliferative diabetic retinopathy. The use of bevacizumab in stage 4 or 5 retinopahty of permaturity (ROP) is to reduce the plus sign to help reduce hemorrhage during the subsequent vitrectomy. …”
Get full text

The PI3K/Akt Signaling Pathway Mediates the High Glucose-Induced Expression of Extracellular Matrix Molecules in Human Retinal Pigment Epithelial Cells by Dong Qin, Guo-ming Zhang, Xun Xu, Li-ya Wang

“…Prolonged hyperglycemia is an important risk factor of the pathogenesis of diabetic retinopathy (DR). Extracellular matrix molecules, such as fibronectin, collagen IV, and laminin, are associated with fibrotic membranes. …”
Get full text

Ursodeoxycholic Acid Attenuates Endoplasmic Reticulum Stress-Related Retinal Pericyte Loss in Streptozotocin-Induced Diabetic Mice by Yoo-Ri Chung, Jeong A. Choi, Jae-Young Koh, Young Hee Yoon

“…Loss of pericytes, an early hallmark of diabetic retinopathy (DR), results in breakdown of the blood-retinal barrier. …”
Get full text

A Computational Model of Peripheral Photocoagulation for the Prevention of Progressive Diabetic Capillary Occlusion by Thomas J. Gast, Xiao Fu, John Scott Gens, James A. Glazier

“…We developed a computational model of the propagation of retinal ischemia in diabetic retinopathy and analyzed the consequences of various patterns and sizes of burns in peripheral retinal photocoagulation. …”
Get full text

Administration of Traditional Chinese Blood Circulation Activating Drugs for Microvascular Complications in Patients with Type 2 Diabetes Mellitus by Lisha He, Han Wang, Chengjuan Gu, Xinhui He, Linhua Zhao, Xiaolin Tong

“…Here, we reviewed the scientific evidence underpinning the use of blood circulation activating drugs to prevent and treat DM-induced microvascular complications, including diabetic nephropathy (DN), diabetic peripheral neuropathy (DPN), and diabetic retinopathy (DR). Furthermore, we summarized the effects and mechanism of TCM on improving blood rheology, inhibiting aggregation of platelet, forming advanced glycation end products (AGEs), regulating oxidative stress, reducing blood fat, and improving lipid metabolism. …”
Get full text

Contribution of Microglia-Mediated Neuroinflammation to Retinal Degenerative Diseases by Maria H. Madeira, Raquel Boia, Paulo F. Santos, António F. Ambrósio, Ana R. Santiago

“…This review aims at giving an overview of the roles of microglia-mediated neuroinflammation in major retinal degenerative diseases like glaucoma, age-related macular degeneration, and diabetic retinopathy.…”
Get full text

Expert Opinion on Fixed Dose Combination of Dapagliflozin Plus Sitagliptin for Unmet Cardiovascular Benefits in Type 2 Diabetes Mellitus by Soumitra Ray, J Ezhilan, Rajiv Karnik, Ashish Prasad, Rajashree Dhar

“…Abstract Type 2 diabetes mellitus (T2DM) is known to be associated with macrovascular (coronary heart disease, stroke, and peripheral arterial disease) and microvascular complications (diabetic kidney disease, retinopathy, and peripheral neuropathy). The coexistence of T2DM with established/risk of atherosclerotic cardiovascular disease (ASCVD), heart failure (HF), or chronic kidney disease confers a poor prognosis, and management can be challenging. …”
Get full text

Detecting Optic Disc on Asians by Multiscale Gaussian Filtering by Bob Zhang, Jane You, Fakhri Karray

“…We tested the proposed method on a new database consisting of 402 images from a diabetic retinopathy (DR) screening programme consisting of Asians. …”
Get full text