Generalized Pruritus and Gradual Loss of Vision as the Presenting Complaints of Acute HIV Infection: Management Challenges during COVID-19 Pandemic by Shrebash Paul, S. M. Mahbubur Rahman, Rajibur Rahman, Mahbubur Rahman, Quazi Mamtaz Uddin Ahmed, Rafiqul Alam, Fazle Rabbi Chowdhury

“…Finally, they were diagnosed with HIV; unfortunately, one of them lost her vision due to CMV retinitis and another patient died of other complications. …”
Get full text

An Update on the Genetics of Usher Syndrome by José M. Millán, Elena Aller, Teresa Jaijo, Fiona Blanco-Kelly, Ascensión Gimenez-Pardo, Carmen Ayuso

“…Usher syndrome (USH) is an autosomal recessive disease characterized by hearing loss, retinitis pigmentosa (RP), and, in some cases, vestibular dysfunction. …”
Get full text

Investigating the Causes of Blindness and Vision Impairment in Children Younger Than 15 Years Old by Abbas Riazi, Fatemeh Riazi

“…The average age of the participants was 3.50±8.99. Congenital retinal diseases include 42% of the causes of blindness and vision impairment in these children. …”
Get full text

Overexpression of MiR-183/96/182 Triggers Retina-Like Fate in Human Bone Marrow-Derived Mesenchymal Stem Cells (hBMSCs) in Culture by Mohammad-Reza Mahmoudian-Sani, Fatemeh Forouzanfar, Samira Asgharzade, Nilufar Ghorbani

“…Retinal degeneration is considered as a condition ensued by different blinding disorders such as retinitis pigmentosa, age-related macular degeneration, and diabetic retinopathy, which can cause loss of photoreceptor cells and also lead to significant vision deficiencies. …”
Get full text

CRISPR/Cas9, a universal tool for genomic engineering by A. V. Smirnov, A. M. Yunusova, V. A. Lukyanchikova, N. R. Battulin

“…For instance, the CRISPR/Cas9 was recently used to control HIV infection and to repair genetic abnormalities, such as Duchenne muscular dystrophy or retinitis pigmentosa, both in cell cultures and rodent models. …”
Get full text

Prevalence, Risk Factors, and Causes of Visual Impairment in an Elderly Chinese Uygur Population in Southern Xinjiang by Yi Sun, Guangming Jin, Mengting Yang, Jing Fu, Xueyi Chen, Bingsheng Lou

“…The major causes of low vision were cataract (42.6%), refractive error (19.6%), and glaucoma (12.6%), whereas the primary causes of blindness were cataract (34%), glaucoma (34%), and retinitis pigmentosa (10%). Conclusions. VI is an important public health issue among elderly Uygur individuals in the area, especially for those with low education levels. …”
Get full text

Novel Compound Heterozygous BBS2 and Homozygous MKKS Variants Detected in Chinese Families with Bardet–Biedl Syndrome by Li Huang, Limei Sun, Zhirong Wang, Songshan Li, Chonglin Chen, Xiaoling Luo, Xiaoyan Ding

“…Both families presented with retinitis pigmentosa; however, except for polydactyly, all other systemic manifestations were different. …”
Get full text

Clinical Features of Optic Disc Drusen in an Ophthalmic Genetics Cohort by Jasmine Y. Serpen, Lev Prasov, Wadih M. Zein, Catherine A. Cukras, Denise Cunningham, Elizabeth C. Murphy, Amy Turriff, Brian P. Brooks, Laryssa A. Huryn

“…As ODD can be associated with visual field defects further compromising already degenerating visual function in patients with retinal degenerations, it is important to further our knowledge of ODD in inherited eye disease. …”
Get full text

A Computational Model of Peripheral Photocoagulation for the Prevention of Progressive Diabetic Capillary Occlusion by Thomas J. Gast, Xiao Fu, John Scott Gens, James A. Glazier

“…We developed a computational model of the propagation of retinal ischemia in diabetic retinopathy and analyzed the consequences of various patterns and sizes of burns in peripheral retinal photocoagulation. …”
Get full text

Publisher Correction: Preliminary investigation on the establishment of a new meibomian gland obstruction model and gene expression by Ming Sun, Huanmin Cheng, Zheng Yang, Jiangqin Tang, Shengshu Sun, Zhanglin Liu, Shaozhen Zhao, Lijie Dong, Yue Huang

Get full text

A Case of Secondary Epiretinal Membrane Spontaneous Release by Andrey N. Andreev, Alexey V. Bushuev, Sergey N. Svetozarskiy

“…We are reporting a case with the history of branch retinal vein occlusion, peripheral retinal neovascularization, and retinal photocoagulation. …”
Get full text

Optical Coherence Tomography Angiography of Two Choroidal Nevi Variants by Victor M. Villegas, Armando L. Monroig, Lazaro H. Aguero, Stephen G. Schwartz

“…Subject one had decreased vascular flow signal in the choroidal, choriocapillaris, deep retinal, and superficial retinal layers. Subject two had decreased vascular flow signal in the choroidal, choriocapillaris, and deep retinal layers with a normal vascular flow signal in the superficial retinal layer. …”
Get full text

Ocular Image and Haemodynamic Features Associated with Different Gradings of Ipsilateral Internal Carotid Artery Stenosis by Hui Wang, Hongyang Li, Xiaojie Zhang, Lanyan Qiu, Zhenchang Wang, Yanling Wang

“…There were no significant differences among the groups in the central retinal artery equivalent (CRAE), central retinal vein equivalent (CRVE), and AVR (p=0.073, p=0.188, and p=0.738, resp.). …”
Get full text

Combination of Multifocal Electroretinogram and Spectral-Domain OCT Can Increase Diagnostic Efficacy of Parkinson’s Disease by Jiang Huang, Yi Li, Jianjiang Xiao, Qin Zhang, Guoxu Xu, Guanhui Wu, Tong Liu, Weifeng Luo

“…Background. The retinal changes have been identified in morphology and function in Parkinson’s disease (PD). …”
Get full text

Prepapillary Vascular Loops Complicated by Suspected Macroaneurysm Rupture by Kei Akaiwa, Yoshinori Mitamura, Takashi Katome, Kentaro Semba, Mariko Egawa, Takeshi Naito

“…Fundus examination disclosed an elevated, round, and reddish lesion, retinal hemorrhage at the superior aspect of the optic disc, retinal opacification along the superior branch retinal artery, and a small vitreous hemorrhage. …”
Get full text

Expression of SIRT1 and DBC1 in Developing and Adult Retinas by Shawn C. Maloney, Emilia Antecka, Alexandre N. Odashiro, Bruno F. Fernandes, Madeline Doyle, Li-Anne Lim, Yousef Katib, Miguel N. Burnier

“…Collectively, the data presented in this study provide support for SIRT1 and DBC1 as regulators of retinal development and normal retinal physiology.…”
Get full text

Profil Penderita Ablasio Retina Eksudatif di Klinik Mata SMEC Tahun 2019-2022 by Lathifah Nur Islami B. Hazami, Nur Khoma Fatmawati, Endang Sawitri

“…Retinal detachment is a critical ocular condition arising from separating two retina layers, leading to an abrupt decline in visual acuity. …”
Get full text

Digital fundus image quality assessment by V. V. Starovoitov, Y. I. Golub, M. M. Lukashevich

“…For this, a new universal retinal image binarization algorithm is proposed. …”
Get full text

The Diagnostic Capability of Swept Source OCT Angiography in Treatment-Naive Exudative Neovascular Age-Related Macular Degeneration by Daniel Ahmed, Martin Stattin, Anna-Maria Haas, Stefan Kickinger, Maximilian Gabriel, Alexandra Graf, Katharina Krepler, Siamak Ansari-Shahrezaei

“…Secondary outcome measure was the anatomic analysis of MNV in relation to the retinal pigment epithelium. Results. En-face SS-OCTA confirmed a MNV in 126 eyes (sensitivity: 79.8%), leaving 32 eyes (20.2%) undetected. …”
Get full text

Macular Holes: Main Clinical Presentations, Diagnosis, and Therapies by Elias Premi, Simone Donati, Lorenzo Azzi, Giovanni Porta, Cristian Metrangolo, Liviana Fontanel, Francesco Morescalchi, Claudio Azzolini

“…Macular holes are a spectrum of retinal diseases that comprehends full-thickness macular holes (FTMHs), refractory/recurrent macular holes, lamellar macular holes (LMHs), myopic macular holes (MMHs), traumatic macular holes, and macular holes secondary to other retinal pathologies or injuries. …”
Get full text