F6H8 as an Intraoperative Tool and F6H8/Silicone Oil as a Postoperative Tamponade in Inferior Retinal Detachment with Inferior PVR by Gian Marco Tosi, Davide Marigliani, Tommaso Bacci, Napoleone Romeo, Angelo Balestrazzi, Gianluca Martone, Tomaso Caporossi

“…To evaluate the effectiveness and safety of perfluorohexyloctane (F6H8) for intraoperative flattening of the retina and of F6H8/silicone oil (SO) 1000 cSt as a postoperative tamponade for inferior retinal detachment with inferior proliferative vitreoretinopathy. …”
Get full text

Management of Wet Age-Related Macular Degeneration in Spain: Challenges for Treat and Extend Implementation in Routine Clinical Practice by A. García-Layana, J. García-Arumí, M. S. Figueroa, L. Arias Barquet, J. M. Ruíz-Moreno, L. Monclús-Arbona, The Spanish AMD Multicenter Group

“…Retina specialists are the main responsible for wAMD diagnosis and monitoring, including visits and associated procedures, with a median time per visit of 15 minutes. …”
Get full text

Epac1 Restores Normal Insulin Signaling through a Reduction in Inflammatory Cytokines by Elizabeth Curtiss, Youde Jiang, Li Liu, Claire Hawthorne, Jessica Zhang, Jena J. Steinle

“…We have previously reported that Epac1 reduced inflammatory cytokines, which is protective to the diabetic retina. We have also published that impaired insulin signaling occurs in the diabetic retina. …”
Get full text

Decreased TNF Levels and Improved Retinal Ganglion Cell Survival in MMP-2 Null Mice Suggest a Role for MMP-2 as TNF Sheddase by Lies De Groef, Manuel Salinas-Navarro, Griet Van Imschoot, Claude Libert, Roosmarijn E. Vandenbroucke, Lieve Moons

“…In this study, we sought to determine the spatiotemporal expression profile of MMP-2 in the excitotoxic retina and to unravel its role during glaucoma pathogenesis. …”
Get full text

Scale-free behavior of weight distributions of connectomes by Michelle Cirunay, Géza Ódor, István Papp, Gustavo Deco

“…In this work, we investigate the weighted degree and connection length distributions of the KKI-113 and KKI-18 human connectomes, the fruit fly, and the mouse retina. We find that the node strength (weighted degree) distribution behavior differs depending on the considered scale. …”
Get full text

Sterile Endophthalmitis after Intravitreal Injections by Joaquín Marticorena, Vito Romano, Francisco Gómez-Ulla

Get full text

Optical Coherence Tomography Angiography of Punctate Inner Choroidopathy by Blake M. Hampton, Christopher M. Aderman, Harry W. Flynn, Jayanth Sridhar

Get full text

EFFICIENT RETINAL IMAGE SEGMENTATION BY U-NET FOR AGE-RELATED MACULAR DEGENERATION DIAGNOSIS by S Sujatha, Pramod Pandey, D Gnana Rajesh

“…Age-related Macular Degeneration (AMD) is a prominent factor contributing to visual impairment in older people, characterized by deterioration of the macula, the center part of the retina. An accurate segmentation of blood vessels is essential for successful intervention and control of MAD. …”
Get full text

Persistence of Retinopathy of Prematurity in an Infant with Tetralogy of Fallot by Murat Gunay, Taner Yavuz, Gokhan Celik, Gunay Uludag

“…At 6 months of postnatal age, the infant still had an avascular peripheral retina with the demarcation line in Zone II. Even though this index subject did not have any typical risk factors for ROP, TOF seems to be the probable reason for developing as well as persistence of avascular retina.…”
Get full text

The Amelioration of Detrimental Biochemical Anomalies by Supplementing B, C, and E Vitamins in Subjects with Type 2 Diabetes Mellitus May Reduce the Rate of Development of Diabetic... by Subhasish Pramanik, Kaustav Banerjee, Lakshmi Kanta Mondal

“…All these detrimental biochemical anomalies ultimately attack biological membranes and especially capillary beds of the retina, resulting in the breakdown of the inner blood-retinal barrier and the initiation of diabetic retinopathy (DR). …”
Get full text

Optic Disk Pit with Sudden Central Visual Field Scotoma by Nikol Panou, Demetrios G. Vavvas

“…OCT revealed absence of serous retinal detachment, but disclosed inner retina thinning corresponding to the area of the visual field loss. …”
Get full text

Divergence in photoreceptor cell death and neuroinflammation in transvitreal and transscleral subretinal delivery in mice by Daniel E. Maidana, Sara Pastor Puente, Catherine Wang, Shivam Chandra, Lucia Gonzalez-Buendia, Eleftherios Paschalis Ilios, Andrius Kazlauskas, Demetrios G. Vavvas

Get full text

Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA): A Targeted Antioxidant Strategy to Counter Oxidative Stress in Retinopathy by Marco Zeppieri, Caterina Gagliano, Fabiana D’Esposito, Mutali Musa, Irene Gattazzo, Maria Sole Zanella, Federico Bernardo Rossi, Alessandro Galan, Silvia Babighian

“…This comprehensive review aims to evaluate the current literature on the role of omega-3 fatty acids, exploring their mechanisms of action and anti-inflammatory, anti-angiogenic, and neuroprotective roles in the retina. Omega-3s have been shown to inhibit abnormal blood vessel growth in the retina, which is a significant factor in proliferative diabetic retinopathy and neovascular AMD. …”
Get full text

Prospective Evaluation of Results of Surgical Treatment of Patients with Idiopathic Macular Hole by Phacovitrectomy and Combined Cataract and Vitrectomy Surgery by Kinga Tochman-Kanty, Monika Jasielska, Jerzy Mackiewicz

“…Material and methods: The study included 33 patients (33 eyes) with idiopathic macular hole treated at the Department of Retina and Vitreous Surgery in Lublin. Twenty-one eyes were surgically treated with phacovitrectomy (Group 1 MH). …”
Get full text

Cellular Signaling in Müller Glia: Progenitor Cells for Regenerative and Neuroprotective Responses in Pharmacological Models of Retinal Degeneration by Yang Liu, Chenguang Wang, Guanfang Su

“…In contrast to stem cells, as embryonic/pluripotent stem cell-derived retinal progenitor cell or mesenchymal stem cells, Müller glia provided an endogenous cellular source for regenerative therapy in the retina. Müller glia are a major component of the retina and considerable evidence suggested these cells can be induced to produce the lost neurons in several species. …”
Get full text

Hematological- and Neurological-Expressed Sequence 1 Gene Products in Progenitor Cells during Newt Retinal Development by Tatsushi Goto, Fumio Tokunaga, Osamu Hisatomi

“…In this study, we investigated the distribution of the HN1 protein, the product of the Hn1 gene, in the developing retinas. Our immunohistochemical analyses suggested that the HN1 protein was highly expressed in an immature retina, and the subcellular localization changed during this retinogenesis as observed in newt retinal regeneration. …”
Get full text

Role of Intravitreal Antivascular Endothelial Growth Factor Injections for Choroidal Neovascularization due to Choroidal Osteoma by Ahmad M. Mansour, J. Fernando Arevalo, Eman Al Kahtani, Hernando Zegarra, Emad Abboud, Rajiv Anand, Hamid Ahmadieh, Robert A. Sisk, Salman Mirza, Samuray Tuncer, Amparo Navea Tejerina, Jorge Mataix, Francisco J. Ascaso, Jose S. Pulido, Rainer Guthoff, Winfried Goebel, Young Jung Roh, Alay S. Banker, Ronald C. Gentile, Isabel Alonso Martinez, Rodney Morris, Neeraj Panday, Park Jung Min, Emilie Mercé, Timothy Y. Y. Lai, Vicky Massoud, Nicola G. Ghazi

Get full text

Retinal Damage Induced by Internal Limiting Membrane Removal by Rachel Gelman, William Stevenson, Claudia Prospero Ponce, Daniel Agarwal, John Byron Christoforidis

“…It has a fundamental role in the development, structure, and function of the retina, although it also is a pathologic component in the various vitreoretinal disorders, most notably in macular holes. …”
Get full text

Surgical and Visual Outcome for Recurrent Retinal Detachment Surgery by Constantin Pournaras, Chrysanthi Tsika, Catherine Brozou, Miltiadis K. Tsilimbaris

“…Anatomical success (attached retina) or failure (totally/partially-detached retina) was assessed biomicroscopically. …”
Get full text

Retinal and Corneal Toxicity and Pharmacokinetic Analysis of Intraocular Injection of Ganciclovir in Rabbit Eyes by Bin-jia Sun, Rong-mei Peng, Qing Lu, Jing Hong

“…Corneal edema was obvious with endothelial cytoarchitecture damaged after intracameral injection; fluid retention also existed in retina. Conclusions. GCV intravitreal injection offers effective, sustained drug concentration in the anterior chamber, and its damage to retina receded over time. …”
Get full text