Single-cell RNA sequencing reveals the heterogeneity and interactions of immune cells and Müller glia during zebrafish retina regeneration by Hui Xu, Lining Cao, Yuxi Chen, Cuiping Zhou, Jie Xu, Zhuolin Zhang, Xiangyu Li, Lihua Liu, Jianfeng Lu

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Outer retina micro-inflammation is driven by T cell responses prior to retinal degeneration in early age-related macular degeneration by Lucas Stürzbecher, Lucas Stürzbecher, Lucas Stürzbecher, Lucas Stürzbecher, Hendrik Bartolomaeus, Hendrik Bartolomaeus, Hendrik Bartolomaeus, Hendrik Bartolomaeus, Theda U. P. Bartolomaeus, Theda U. P. Bartolomaeus, Theda U. P. Bartolomaeus, Theda U. P. Bartolomaeus, Sylvia Bolz, Andjela Sekulic, Marius Ueffing, Marius Ueffing, Simon J. Clark, Simon J. Clark, Simon J. Clark, Nadine Reichhart, Sergio Crespo-Garcia, Nicola Wilck, Nicola Wilck, Nicola Wilck, Nicola Wilck, Olaf Strauß

“…As further evidence for the contribution of the adaptive immune system to GA we identified an increased frequency of CD44+ CD69+ KLRG1+ T cells and para-inflammation of the retina in a mouse model that mimics features of GA. …”
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Enhanced Expression of NR2B Subunits of NMDA Receptors in the Inherited Glaucomatous DBA/2J Mouse Retina by Ling-Dan Dong, Jie Chen, Fang Li, Feng Gao, Jihong Wu, Yanying Miao, Zhongfeng Wang

“…Here, we investigated changes in expression of NMDA receptor (NMDAR) subunits and Cdk5/p35/NMDAR signaling in retinas of DBA/2J mice using Western blot technique. …”
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Cone photoreceptor phosphodiesterase PDE6H inhibition regulates cancer cell growth and metabolism, replicating the dark retina response by Ceren Yalaz, Esther Bridges, Nasullah K. Alham, Christos E. Zois, Jianzhou Chen, Karim Bensaad, Ana Miar, Elisabete Pires, Ruth J. Muschel, James S. O. McCullagh, Adrian L. Harris

“…We show that in HCT116, PDE6H deletion replicates many effects of the dark retina response and identify PDE6H as a new target in preventing cancer cell proliferation and tumour growth.…”
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Correction to: Cone photoreceptor phosphodiesterase PDE6H inhibition regulates cancer cell growth and metabolism, replicating the dark retina response by Ceren Yalaz, Esther Bridges, Nasullah K. Alham, Christos E. Zois, Jianzhou Chen, Karim Bensaad, Ana Miar, Elisabete Pires, Ruth J. Muschel, James S. O. McCullagh, Adrian L. Harris

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Combined Hamartoma of the Retina and Retinal Pigment Epithelium in a Patient with Gorlin Syndrome: Spontaneous Partial Resolution of Traction Caused by Epiretinal Membrane by José L. Sánchez-Vicente, Miguel Contreras-Díaz, Trinidad Rueda, Enrique Rodríguez de la Rúa-Franch, Fredy E. Molina-Socola, Cristina Vital-Berral, Asunción Alfaro-Juárez, Fernando López-Herrero, Ana Muñoz-Morales

“…To describe the case of spontaneous resolution of epiretinal membrane in a patient with Combined Hamartoma of the Retina and Retinal Pigment Epithelium (CHR-RPE), in the clinical context of Gorlin Syndrome (GS). …”
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The Mitochondria-Targeted Antioxidant SkQ1 Downregulates Aryl Hydrocarbon Receptor-Dependent Genes in the Retina of OXYS Rats with AMD-Like Retinopathy by M. L. Perepechaeva, A. Yu. Grishanova, E. A. Rudnitskaya, N. G. Kolosova

“…The aim of this work was to test whether SkQ1 affects transcriptional activity of AhR (aryl hydrocarbon receptor) and Nrf2 (nuclear factor erythroid 2-related factor 2), which are considered as AMD-associated genes in the retina of OXYS and Wistar rats. Our results showed that only AhR and AhR-dependent genes were sensitive to SkQ1. …”
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Recurrent Diffuse Large B-Cell Lymphoma with the Initial Manifestation of Retinal Involvement by Wan-Ting Yeh, Jen-Tsun Lin*

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"Energetics of the outer retina II: Calculation of a spatio-temporal energy budget in retinal pigment epithelium and photoreceptor cells based on quantification of cellular processes". by Christina Kiel, Stella Prins, Alexander J E Foss, Philip J Luthert

“…The outer retina (OR) is highly energy demanding. Impaired energy metabolism combined with high demands are expected to cause energy insufficiencies that make the OR susceptible to complex blinding diseases such as age-related macular degeneration (AMD). …”
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Modeling sacsin depletion in Danio Rerio offers new insight on retinal defects in ARSACS by Valentina Naef, Devid Damiani, Rosario Licitra, Maria Marchese, Stefania Della Vecchia, Matteo Baggiani, Letizia Brogi, Daniele Galatolo, Silvia Landi, Filippo Maria Santorelli

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NLRX1 limits inflammatory neurodegeneration in the anterior visual pathway by Alexander J. Gill, Matthew D. Smith, Danny Galleguillos, Thomas Garton, Jackson W. Mace, Sachin P. Gadani, Swati Kumar, Aayush Pokharel, Krista Solem, Saahith Potluri, Omar Hussein, Giuliana Sardi Rogines, Arihant Singh, Annatje Clark, Peter A. Calabresi, Marjan Gharagozloo

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Retinal optical coherence tomography intensity spatial correlation features as new biomarkers for confirmed Alzheimer’s disease by Zi Jin, Xinmin Wang, Ying Lang, Yufeng Song, Huangxiong Zhan, Wuge Shama, Yingying Shen, Guihua Zeng, Faying Zhou, Hongjian Gao, Shuling Ye, Yanjiang Wang, Fan Lu, Meixiao Shen

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Minimally Invasive Vitreoretinal Surgery (25G, 27G) with High-speed Vitrectomy Cutter – Case Series by Krzysztof Broniarek, Katarzyna Michalska-Małecka

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LEONARDO DA VINCI Y LA COMPARACIÓN OJO-CÁMARA OBSCURA by CARLOS ALBERTO CARDONA

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Application of optical coherence tomography angiography to study retinal and choroidal vascular changes in patients with first-time coronary artery stenosis by Rongrong Guan, Shuyan Qin, Yezhu Chi, Zhen Tang, Haiyang Liu

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Overexpression of MiR-183/96/182 Triggers Retina-Like Fate in Human Bone Marrow-Derived Mesenchymal Stem Cells (hBMSCs) in Culture by Mohammad-Reza Mahmoudian-Sani, Fatemeh Forouzanfar, Samira Asgharzade, Nilufar Ghorbani

“…To this end, miR-183/96/182 cluster was transfected into hBMSCs; then, qRT-PCR was performed to measure the expression levels of miR-183/96/182 cluster and some retina-specific neuronal genes such as OTX2, NRL, PKCα, and recoverin. …”
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Selective retina therapy with real-time feedback-controlled technology in central serous chorioretinopathy: a 24-month follow-up real-world prospective study by Hyeong Gon Yu, Chang Ki Yoon

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Altered Expression of NF-κB and SP1 after Exposure to Advanced Glycation End-Products and Effects of Neurotrophic Factors in AGEs Exposed Rat Retinas by Guzel Bikbova, Toshiyuki Oshitari, Takayuki Baba, Shuichi Yamamoto

“…Statistical analyses were performed by one-way ANOVA. In retinas incubated with AGEs, the numbers of neurites were fewer than in control. …”
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Risk of Posterior Capsular Rupture during Phacoemulsification in Patients with the History of Anti-VEGF Intravitreal Injections: Results from the Pan-American Collaborative Retina Study (PACORES) Group by Raul Velez-Montoya, Idaira Sanchez-Santos, Mauricio Galvan-Chavez, Lihteh Wu, J. Fernando Arevalo, María H. Berrocal, Arturo A. Alezzandrini, Marta S. Figueroa, Roberto Gallego-Pinazo, Rosa Dolz-Marco, Clara Martinez-Rubio, Roberto Gonzalez-Salinas

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The endocannabinoid system and ophthalmic pathologies: a review of molecular mechanisms and its implications for clinical practice by Tomasz Charytoniuk, Stanisław Półjanowski, Mateusz Michalak, Karolina Kaźmierczak, Bartłomiej Kałużny

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