A New Mechanism of Silicone Oil-Induced Glaucoma and Its Management by Harsh Kumar, Dinesh Talwar, Mithun Thulasidas, Surbi Taneja

“…Fundus examination of LE showed silicone oil filled vitreous cavity with attached retina. Given the recent history of silicone oil injection and elevated IOP despite maximum antiglaucoma medications, we decided to perform laser peripheral iridotomy (LPI) in the area of iridocorneal apposition. …”
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Retinitis Pigmentosa and Bilateral Idiopathic Demyelinating Optic Neuritis in a 6-Year-Old Boy with OFD1 Gene Mutation by Xun Wang, Cong Zheng, Wen Liu, Hui Yang

“…The patient had a history of night blindness, a mottled retina without pigmentation, extinguished electroretinographic response, tritanopia, and an absent ellipsoid zone outside the macula fovea by optical coherence tomography in both eyes. …”
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Comparative Study between Pars Plana Vitrectomy with Internal Limiting Membrane Peel and Pars Plana Vitrectomy with Internal Limiting Membrane Flap Technique for Management of Trau... by Hammouda Hamdy Ghoraba, Mahmoud Leila, Hashem Ghoraba, Mohamed Amin Heikal, Emad Eldin Mohamed Elgemai

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Mutational Profile and Retinal Phenotypes of PCARE-Related Cone-Rod Dystrophies in a Mexican Cohort by Víctor R. López-Rodríguez, Rocío Arce-González, Alan Martínez-Aguilar, Carlos E. Rodríguez-López, Sergio Groman-Lupa, M. Isabel Neria-González, Genaro Rodríguez-Uribe, Juan C. Zenteno

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Correlation between Retinal Changes and Visual Function in Late-Stage Vogt-Koyanagi-Harada Disease: An Optical Coherence Tomography Study by Min Zhou, Chunhui Jiang, Ruiping Gu, Zhongcui Sun, Nancy Huynh, Qing Chang

“…The OCT revealed that the outer retina and retinal pigment epithelium (RPE) were mainly affected. …”
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NLRP3 Inflammasome: Activation and Regulation in Age-Related Macular Degeneration by Jiangyuan Gao, Ruozhou Tom Liu, Sijia Cao, Jing Z. Cui, Aikun Wang, Eleanor To, Joanne A. Matsubara

“…Progression of AMD is characterized by an increase in the number and size of drusen, extracellular deposits, which accumulate between the retinal pigment epithelium (RPE) and Bruch’s membrane (BM) in outer retina. The major pathways associated with its pathogenesis include oxidative stress and inflammation in the early stages of AMD. …”
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Expanding of Excimer Laser Photoablation’s Functionality in Ophthalmology by V. A. Alekseev, V. G. Kostin, A. V. Usoltseva, V. P. Usoltsev, S. I. Yuran

“…One of the significant weaknesses of excimer laser-based vision correction devices is the difficulty of achieving a required change in the refractive properties of the cornea to sharply focus the image on the retina with distance from the working area (ablation zone) center to the periphery due to a change in the laser beam incidence angle. …”
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Peripheral Refraction in Myopic Children with and without Atropine Usage by Han-Yin Sun, Wei-Yang Lu, Jhen-Yu You, Hui-Ying Kuo

“…There were no statistically significant differences in spherical equivalent and astigmatism of the three refractive groups in either the nasal or temporal retina. The atropine group showed a significant relative myopia in the temporal 30° field in spherical equivalent compared to the emmetropic group (t49 = 3.36, P=0.02). …”
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Synergistic effect of defocus incorporated multiple segment glasses and repeated low level red light therapy against myopia progression by Yan Yang, Shenghong Liu, Wenwen Gao, Lei Wang, Na Liu, Shiying Zhang, Lianjing Yang, Lingyun Cheng

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Multimodal Imaging Characteristics of ADRP in a Family with p.Thr58Arg Substituted RHO Mutation by Misty Ruppert, John Pyun, K. V. Chalam, David Sierpina

“…Wide area of dystrophic retina was noted on UWF-FAF, along with corresponding atrophy of photoreceptor layer on OCT. …”
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The Dissemination of Rift Valley Fever Virus to the Eye and Sensory Neurons of Zebrafish Larvae Is Stat1-Dependent by Sebastiaan ter Horst, Aleksandra Siekierska, Ann-Sofie De Meulemeester, Arno Cuvry, Laura Cools, Johan Neyts, Peter de Witte, Joana Rocha-Pereira

“…The optical transparency of the larvae allowed detection of RVFV_eGFP in the liver and sensory nervous system, including the optic tectum and retina, but not the brain or spinal cord. Thus, RVFV-induced blindness likely occurs due to direct damage to the eye and peripheral neurons, rather than the brain. …”
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Blockade of Vascular Endothelial Growth Factor Receptor 1 Prevents Inflammation and Vascular Leakage in Diabetic Retinopathy by Jianbo He, Hong Wang, Ying Liu, Wen Li, Dorothy Kim, Hu Huang

“…Vascular leakage was evaluated by measuring the leakage of [3H]-mannitol tracer into the retina and the IF staining of albumin. VEGFR1 blockade significantly inhibited diabetes-related vascular leakage, leukocytes-endothelial cell (EC) adhesion (or retinal leukostasis), expression of intercellular adhesion molecule- (ICAM-) 1 protein, abnormal localization and degeneration of the tight junction protein zonula occludens- (ZO-) 1, and the cell adhesion protein vascular endothelial (VE) cadherin. …”
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Analysis of Foveal and Parafoveal Microvascular Density and Retinal Vessel Caliber Alteration in Inactive Graves’ Ophthalmopathy by Cetin Akpolat, Muhammed M. Kurt, Merve Yılmaz, Fikriye Ordulu, Ferhat Evliyaoglu

“…Foveal and parafoveal microvascular density in the retina was measured using optical coherence tomography angiography. …”
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Is the Retinal Vasculature Related to β-Peripapillary Atrophy in Nonpathological High Myopia? An Optical Coherence Tomography Angiography Study in Chinese Adults by Jiao Sun, Jialin Wang, Ran You, Yanling Wang

“…Vessel density and fractal dimensions of the retina and foveal avascular zone were analysed and quantified using en face projection images. …”
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Six-Year Real-World Outcomes of Antivascular Endothelial Growth Factor Monotherapy and Combination Therapy for Various Subtypes of Polypoidal Choroidal Vasculopathy by Jingyuan Yang, Mingzhen Yuan, Song Xia, Youxin Chen

“…In subtype 2 PCV eyes with continuous retina pigment epithelium, the mean changes of BCVA in eyes treated with anti-VEGF monotherapy were better than those in eyes treated with combination therapy (P=0.020). …”
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In Vivo Confocal Microscopy Findings in Corneal Stromal Dystrophies by Süleyman Okudan, Emine Tınkır Kayıtmazbatır, Ayşe Bozkurt Oflaz, Banu Bozkurt

“…IVCM was performed using the Heidelberg Retina Tomograph 3, Rostock Cornea Module (Heidelberg Engineering, Germany) and anterior segment optical coherence tomography (AS-OCT) imaging was performed using the Spectralis OCT (Heidelberg Engineering, Germany). …”
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Integrating electrocardiogram and fundus images for early detection of cardiovascular diseases by K. A. Muthukumar, Dhruva Nandi, Priya Ranjan, Krithika Ramachandran, Shiny PJ, Anirban Ghosh, Ashwini M, Aiswaryah Radhakrishnan, V. E. Dhandapani, Rajiv Janardhanan

“…Recognizing the intricate vascular network of the retina as a reflection of the cardiovascular system, alongwith the dynamic cardiac insights from ECG, we sought to provide a holistic diagnostic perspective. …”
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The “Triangle” Sign: A Novel Ultrasound Marker for Diagnosing Total Choroidal Detachment and Total Suprachoroidal Hemorrhage by Bhatt VD, Bhatt DC, Bhatt KD, Dabir S, Berendschot TTJM, Erckens RJ, Webers CAB

“…Vaidehi D Bhatt,1 Deepak C Bhatt,1 Kalpana D Bhatt,1 Supriya Dabir,2 Tos TJM Berendschot,3 Roel J Erckens,3 Carroll AB Webers3 1UBM Institute, Mumbai, India; 2Department of Retina, Rajan Eye Care Pvt Ltd, Chennai, India; 3University Eye Clinic Maastricht, Maastricht, the NetherlandsCorrespondence: Vaidehi D Bhatt, UBM Institute, A/1 Ganesh Baug, Dadar, Mumbai, 400019, India, Tel +91-9821525810, Email vaidehibhatt94@gmail.comPurpose: This study aims to explore the diagnostic utility of ultrasound B-scan while introducing the “Triangle” sign as a novel indicator. …”
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Combination of Intravitreal Injection of Ranibizumab and Photocoagulation for the Treatment of Aggressive Posterior Retinopathy of Prematurity with Vitreous Hemorrhage by Yu Xu, Xiaoli Kang, Qi Zhang, Qiujing Huang, Jiao Lv, Peiquan Zhao

“…All eyes exhibited adequate regression of ROP and were stable with attached retina. Fibrosis membrane was observed in seven eyes (18.9%) and three of them demonstrated mild ectopic macula. …”
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Fundus Autofluorescence and Spectral Domain OCT in Central Serous Chorioretinopathy by Luiz Roisman, Daniel Lavinsky, Fernanda Magalhaes, Fabio Bom Aggio, Nilva Moraes, Jose A. Cardillo, Michel E. Farah

“…NIA has been related to the choroidal melanin content and there were areas of both increased and decreased NIA, which could be explained by damage ahead the retina, basically RPE and choroid. These findings, along with the PEDs found in the areas of hypoNIA, support the notion of a primary choroidal disease in CSC.…”
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