Circadian Plasticity of Mammalian Inhibitory Interneurons by Malgorzata Jasinska, Elzbieta Pyza

“…Here we review the circadian plasticity of GABAergic interneurons in several areas of the mammalian brain, suprachiasmatic nucleus, neocortex, hippocampus, olfactory bulb, cerebellum, striatum, and in the retina.…”
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Pleiotropic effects of mutant huntingtin on retinopathy in two mouse models of Huntington's disease by Hui Xu, Anakha Ajayan, Ralf Langen, Jeannie Chen

“…This mutant huntingtin protein (mHTT) with extended polyQ forms aggregates in cortical and striatal neurons, causing cell damage and death. The retina is part of the central nervous system (CNS), and visual deficits and structural abnormalities in the retina of HD patients have been observed. …”
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Saffron therapy for the ongoing treatment of age-related macular degeneration by Peter J McCluskey, Thomas Hong, Andrew A Chang, John Grigg, Geoffrey K Broadhead, Timothy E Schlub, Eugenia Chu

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Glucose-Sensing Carbohydrate Response Element-Binding Protein in the Pathogenesis of Diabetic Retinopathy by Christopher R. Starr, Assylbek Zhylkibayev, Oleg Gorbatyuk, Alli M. Nuotio-Antar, James Mobley, Maria B. Grant, Marina Gorbatyuk

“…Our results demonstrate that both proteins were expressed across the retina, although with distinct distribution patterns: MondoA was more prominently expressed in cones, while ChREBP was broadly expressed throughout the retina. …”
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Early Macular Angiography among Patients with Glaucoma, Ocular Hypertension, and Normal Subjects by Shih-Chun Chao, Shang-Jung Yang, Hung-Chi Chen, Chi-Chin Sun, Chin-Hsin Liu, Chia-Yi Lee

“…The flow area of the outer retina in the OAG group was low relative to those of the OHT and control groups. …”
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Abnormalities in Glutamate Metabolism and Excitotoxicity in the Retinal Diseases by Makoto Ishikawa

“…In the physiological condition, glutamate acts as an excitatory neurotransmitter in the retina. However, excessive glutamate can be toxic to retinal neurons by overstimulation of the glutamate receptors. …”
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Choroid vascular index in myopic patients – A mini review by Sheng-Chu Chi, Yi-Ming Huang

“…The choroid plays a vital role in myopia, and its changes tend to occur earlier than those of the retina and long-term variations in eye growth. Abnormal axial growth is an intrinsic characteristic of myopia, accompanied by ocular biomechanical changes that result in chorioretinal atrophy, thinning, and other complications particularly in the choroidal vasculature. …”
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Uniplanar Nystagmus Associated with Perceptual and Cognitive Visual Dysfunction due to Presumed Focal Ischemic Occipital Cortical Atrophy: A Missed Diagnosis and New Observation by Swetha Sara Philip, Gordon N. Dutton, Liam Dorris

“…Uniplanar nystagmus has been described in relation to pathology of the brain stem, retina, optic nerve, sensory visual deprivation, periventricular leucomalacia, and drug toxicity. …”
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Deep-Reticular Pseudodrusen-Net: A 3-Dimensional Deep Network for Detection of Reticular Pseudodrusen on OCT Scans by Amr Elsawy, PhD, Tiarnan D.L. Keenan, PhD, MD, Alisa T. Thavikulwat, MD, Amy Lu, MD, Sunil Bellur, MD, Souvick Mukherjee, PhD, Elvira Agron, MS, Qingyu Chen, PhD, Emily Y. Chew, MD, Zhiyong Lu, PhD

“…The performance of Deep-RPD-Net was compared to that of 3 retina specialists on a subset of 50 OCT scans for each dataset. …”
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Reprogramming of Adult Retinal Müller Glial Cells into Human-Induced Pluripotent Stem Cells as an Efficient Source of Retinal Cells by Amélie Slembrouck-Brec, Amélie Rodrigues, Oriane Rabesandratana, Giuliana Gagliardi, Céline Nanteau, Stéphane Fouquet, Gilles Thuret, Sacha Reichman, Gael Orieux, Olivier Goureau

“…In this study, we demonstrated that the major type of glial cells of the human retina, Müller cells, can be reprogrammed into iPSCs that acquire classical signature of pluripotent stem cells. …”
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Hematopoietic stem cell transplantation as rescue therapy for refractory autoimmune retinopathy: a case report by Wendy Meihua Wong, Wendy Meihua Wong, Yvonne Loh, Hwei Wuen Chan, Hwei Wuen Chan, Warren Fong, Soon-Phaik Chee, Soon-Phaik Chee, Adrian Koh, Graham E. Holder, Graham E. Holder

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One-Year Outcomes in Subjects Developing Macular Neovascularization While Undergoing Avacincaptad Pegol Therapy for Geographic Atrophy by Rush RB, Klein W, Rush SW, Reinauer R

“…Ryan B Rush,1– 3 Westin Klein,1 Sloan W Rush,1,2 Robert Reinauer4 1Department of Ophthalmology, Panhandle Eye Group, Amarillo, TX, USA; 2Department of Surgery, Texas Tech University Health Science Center, Amarillo, TX, USA; 3Department of Ophthalmology, Southwest Retina Specialists, Amarillo, TX, USA; 4Department of Ophthalmology, New Vision Eye Center, Vero Beach, FL, USACorrespondence: Ryan B Rush, Southwest Retina Specialists, 7411 Wallace Blvd, Amarillo, TX, 79106, USA, Tel +1806 351 1870, Email ryan.rush.md@gmail.comPurpose: To assess the 12-month outcomes in subjects developing macular neovascularization (MNV) during intravitreal avacincaptad pegol (IVA) treatment for geographic atrophy (GA) secondary to age-related macular degeneration (AMD).Methods: This research was conducted as a case-controlled, retrospective study of AMD subjects undergoing IVA treatment for GA from two private practice institutions. …”
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Assessing static balance control improvement following cataract surgery using a smartphone by Lorrana de Souza Azevedo, Newton Quintino Feitosa, Enzo Gabriel Rocha Santos, Márcio Augusto Moraes Alvarez, Lucciano Augusto Ximenes Norat, Gabriel Izan Santos Botelho, Anderson Belgamo, Gustavo Henrique Lima Pinto, Ketlin Jaqueline Santana Castro, Bianca Callegari, Anselmo de Athayde Costa e Silva, Raílson Cruz Salomão, André dos Santos Cabral, Alexandre Antônio Marques Rosa, Givago Silva Souza

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Detection of Body Packs in Abdominal CT scans Through Artificial Intelligence; Developing a Machine Learning-based Model by Sayed Masoud Hosseini, Seyed Ali Mohtarami, Shahin Shadnia, Mitra Rahimi, Peyman Erfan Talab Evini, Babak Mostafazadeh, Azadeh Memarian, Elmira Heidarli

“…A single-step object detection called RetinaNet using a modified neck (Proposed Model) was performed to achieve the best results. …”
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Evaluation of Changes in Macular Perfusion Detected by Optical Coherence Tomography Angiography following 3 Intravitreal Monthly Bevacizumab Injections for Diabetic Macular Edema i... by Ayman G. Elnahry, Ahmed A. Abdel-Kader, Karim A. Raafat, Khaled Elrakhawy

“…Pretreatment and posttreatment OCTA images were automatically aligned using a commercially available retina alignment software (i2k Align Retina software); then the fractal dimension (FD), vascular density (VD), and skeleton VD changes were obtained at the full retinal thickness (Full) and superficial (SCP) and deep (DCP) capillary plexuses after processing images using a semiautomated program. …”
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Intravitreal Brolucizumab for Choroidal Neovascularization Associated to Angioid Streaks by Somnath Chakraborty, Jay Umed Sheth

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Registration and Fusion of the Autofluorescent and Infrared Retinal Images by Radim Kolar, Libor Kubecka, Jiri Jan

“…This article deals with registration and fusion of multimodal opththalmologic images obtained by means of a laser scanning device (Heidelberg retina angiograph). The registration framework has been designed and tested for combination of autofluorescent and infrared images. …”
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Nonsteroidal Anti-Inflammatory Drugs for Retinal Disease by Scott D. Schoenberger, Stephen J. Kim

“…These changes may allow for greater drug penetration into the retina and thereby offer additional therapeutic advantages. …”
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Changes in Aqueous Humor Cytokine Profile Following Intravitreal Brolucizumab Injection by Ruamviboonsuk V, Kongwattananon W, Chuaypen N

“…Varis Ruamviboonsuk,1,2 Wijak Kongwattananon,1,3 Natthaya Chuaypen4 1Department of Ophthalmology, King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand; 2Medical Science Program, Department of Biochemistry, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; 3Center of Excellence in Retina, Department of Ophthalmology, Faculty of Medicine Chulalongkorn University and King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand; 4Metabolic Diseases in Gut and Urinary System Research Unit (MeDGURU), Department of Biochemistry, Faculty of Medicine, Chulalongkorn University, Bangkok, ThailandCorrespondence: Wijak Kongwattananon, Center of Excellence in Retina, Department of Ophthalmology, Faculty of Medicine Chulalongkorn University and King Chulalongkorn Memorial Hospital, Thai Red Cross Society, 1873 Rama IV Road, Pathum Wan, Bangkok, 10330, Thailand, Tel +662 256 4000, Email wijak.k@chula.ac.thPurpose: Intravitreal brolucizumab, approved for neovascular age-related macular degeneration (nAMD), may trigger immune responses leading to intraocular inflammation (IOI) by increasing pro-inflammatory cytokines. …”
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Lutein and inflammation: a comprehensive review of its mechanisms of action by Paradentavida Prathyusha, Geetha Viswanathan, Anjilikal Tomy Tomcy, Ponnamparambil P. Binitha, Smitha V. Bava, Edakkadath R. Sindhu

“…It is well-absorbed and systemically localized to the liver, lung, and retina, where it can cross the blood-retina barrier and accumulate in the macular pigment. …”
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