Analysis of respiratory pathogen detection in hospitalized children with acute respiratory tract infections after ending the zero COVID policy by Xuena Xu, Yizhu Zhang, Lina Xu, Wujun Jiang, Chuangli Hao

“…Nasopharyngeal aspirates (NPAs) were obtained from children with ARTIs (aged ≤ 16 years) at the Children’s Hospital of Soochow University for the detection of respiratory syncytial virus (RSV), influenza A (FluA), FluB, human parainfluenza virus (HPIV), adenovirus (ADV), human rhinovirus (HRV), bocavirus (BoV), human metapneumovirus (HMPV), and mycoplasma pneumoniae (MP). …”
Get full text

Attitude to RSV Vaccination Among a Cohort of Pregnant Women in Jordan: A Cross‐Sectional Survey Study by Malik Sallam, Tleen Kherfan, Amwaj Al‐Farajat, Leen Nemrawi, Nada Atawneh, Rand Fram, Ala'a B. Al‐Tammemi, Muna Barakat, Kamil Fram

“…ABSTRACT Background and Aims The recently approved maternal vaccination against respiratory syncytial virus (RSV) can reduce its burden among infants. …”
Get full text

Respiratory pathogen spectrum and epidemiological trends in Hainan Province: a retrospective analysis from 2017 to 2023 by Lvying Wu, Jianan Zhang, Zhiming Wu, Hua Pei, You Zhang

“…A total of 21,036 patients with RTI of all age groups were enrolled and tested for nine common pathogens: influenza A virus (Flu-A), influenza B virus (Flu-B), parainfluenza virus (PIV), Adenovirus (AAV), respiratory syncytial virus (RSV), Q fever Rickettsiae (Q Fever), Legionella pneumophila (L. pne), Chlamydia pneumoniae (C. pne), and Mycoplasma pneumoniae (M. pne). …”
Get full text

A phase I, randomized, placebo‐controlled trial to evaluate the pharmacokinetics, safety, and tolerability of nirsevimab in healthy Chinese adults by Xiaomeng Mao, Xiaohan Hua, Chengyi Wu, Xiaoyun Ge, Jie Zhang, Xiaojie Wu, Robert J. Kubiak, Ulrika Wählby Hamrén, Tonya Villafana, Georgios Christou, Jannine Green, Therese Takas, Yuwen Jin

“…Abstract Respiratory syncytial virus (RSV) is the leading cause of lower respiratory tract infection (LRTI) in infants worldwide. …”
Get full text

Assessing the long-term economic impact of wheezing episodes after severe RSV disease in children from Argentina: a cost of illness analysis by Ranju Baral, Clint Pecenka, Elisabeth Vodicka, Andrea Rodríguez, Romina Libster, Julia Dvorkin, Emiliano M Sosa, Andrea Sancilio, Karina Dueñas, Carlos Rojas-Roque, Patricia B Carruitero, Fernando P Polack, Mauricio T Caballero

“…Introduction There is lack of available data on the economic burden of wheezing episodes after severe respiratory syncytial virus (RSV) infection. This study aimed to assess the cost incurred for wheezing episodes after a severe RSV infection in children from Argentina, considering both the public health system and societal perspectives.Methods A prospective cohort was conducted from 2014 to 2022 to assess the cost of illness of wheezing episodes after severe RSV disease in children from Buenos Aires, Argentina. …”
Get full text

Implementasi Algoritma BFCC dan kNN pada Embedded System untuk Deteksi Dini Bronchitis by Septiyo Budi Perkasa, Barlian Henryranu Prasetio, Eko Setiawan, Edita Rosana Widasari, Dahnial Syauqy

“…Bronchitis is a disease that can be caused by respiratory syncytial virus (RSV) and rhinovirus. Symptoms of common bronchitis a person will experience difficulty breathing accompanied by coughing. …”
Get full text

Advances and Challenges in Antiviral Development for Respiratory Viruses by Luis Adrián De Jesús-González, Moisés León-Juárez, Flor Itzel Lira-Hernández, Bruno Rivas-Santiago, Manuel Adrián Velázquez-Cervantes, Iridiana Monserrat Méndez-Delgado, Daniela Itzel Macías-Guerrero, Jonathan Hernández-Castillo, Ximena Hernández-Rodríguez, Daniela Nahomi Calderón-Sandate, Willy Salvador Mata-Martínez, José Manuel Reyes-Ruíz, Juan Fidel Osuna-Ramos, Ana Cristina García-Herrera

“…The development of antivirals for respiratory viruses has advanced markedly in response to the growing threat of pathogens such as Influenzavirus (IAV), respiratory syncytial virus (RSV), and SARS-CoV-2. This article reviews the advances and challenges in this field, highlighting therapeutic strategies that target critical stages of the viral replication cycle, including inhibitors of viral entry, replication, and assembly. …”
Get full text

Epidemiology of community-acquired pneumonia among hospitalised children in Indonesia: a multicentre, prospective study by Rina Triasih, Yan Mardian, Dewi Lokida, Helmia Farida, Herman Kosasih, Adhella Menur Naysilla, Arif Budiman, Chakrawati Hayuningsih, Moh Syarofil Anam, Dwi Wastoro, Mujahidah Mujahidah, Setya Dipayana, Amalia Setyati, Abu Tholib Aman, Nurhayati Lukman, Muhammad Karyana, Ahnika Kline, Aaron Neal, Chuen-Yen Lau, Clifford Lane

“…The five most common causative pathogens identified were Haemophilus influenzae non-type B (N=73, 38.8%), respiratory syncytial virus (RSV) (N=51, 27.1%), Klebsiella pneumoniae (N=43, 22.9%), Streptococcus pneumoniae (N=29, 15.4%) and Influenza virus (N=25, 13.3%). …”
Get full text

Changes in infant respiratory pathogens pre-, during, and post-COVID-19 non-pharmacological interventions in Beijing by Tongying Han, Yajuan Wang, Di Zhang, Ying Li, Li Zhang, Jin Yan, Chi Li, Shengnan Yang, Litao Guo, Huijuan Yan

“…The specimens were tested for 14 respiratory pathogens, including influenza virus A (Flu A), influenza virus B, respiratory syncytial virus, parainfluenza virus (PIV), adenovirus (ADV), human metapneumovirus (HMPV), human bocavirus, human rhinovirus (HRV), coronavirus, Chlamydia trachomatis, Chlamydia pneumoniae (C.pn), Mycoplasma pneumoniae, Bordetella pertussis, and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). …”
Get full text

DS2 designer pre-fusion F vaccine induces strong and protective antibody response against RSV infection by Yiling Yang, Ruoke Wang, Fenglin Guo, Tian Zhao, Yuqing Lei, Qianqian Yang, Yige Zeng, Ziqing Yang, Tatchapon Ajavavarakula, Ruijie Tan, Mingxi Li, Haodi Dong, Mengyue Niu, Keyan Bao, Hao Geng, Qining Lv, Qi Zhang, Xuanling Shi, Peng Liu, Jiwan Ge, Xinquan Wang, Linqi Zhang

“…Abstract DS-Cav1, SC-TM, and DS2 are distinct designer pre-fusion F proteins (pre-F) of respiratory syncytial virus (RSV) developed for vaccines. However, their immunogenicity has not been directly compared. …”
Get full text

Protective or limited? Maternal antibodies and RSV-associated lower respiratory tract infection in hospitalized infants aged 28-90 days by Shuanglian Li, Shuanglian Li, Chenghao Mei, Chenghao Mei, Sainan Chen, Chenglin Wang, Chenglin Wang, Yelei Gao, Yelei Gao, Jinhua Ma, Jinhua Ma, Li Zhong, Li Zhong, Tingting Luo, Tingting Luo, Xin Zhao, Xin Zhao, Huaqin Bu, Huaqin Bu, Ying Lyu, Ying Lyu, Xiaohu Kuang, Zhenxing Jia, Xiaoli Wang, Yuqing Wang, Daiyin Tian, Daiyin Tian, Daiyin Tian

“…BackgroundRespiratory syncytial virus (RSV) is a major cause of severe health problems in newborns and young children. …”
Get full text

The Role of RSV Infection in Asthma Initiation and Progression: Findings in a Mouse Model by Junyan Han, Katsuyuki Takeda, Erwin W. Gelfand

“…Respiratory syncytial virus (RSV) is a common cause of severe lower respiratory tract diseases (bronchiolitis and pneumonia) during infancy and early childhood. …”
Get full text

Regulated microbe vaccines: from concept to (pre-clinical) reduction to practice by Richard Voellmy, David C Bloom, Nuria Vilaboa

“…SARS-CoV-2), respiratory syncytial viruses (RSV), and human immunodeficiency viruses (HIV) have remained insufficiently effective or are not available at all. …”
Get full text

Immunogenicity of RSV F DNA Vaccine in BALB/c Mice by Erdal Eroglu, Ankur Singh, Swapnil Bawage, Pooja M. Tiwari, Komal Vig, Shreekumar R. Pillai, Vida A. Dennis, Shree R. Singh

“…Respiratory syncytial virus (RSV) causes severe acute lower respiratory tract disease leading to numerous hospitalizations and deaths among the infant and elderly populations worldwide. …”
Get full text