A hammerhead ribozyme selects mechanically stable conformations for catalysis against viral RNA by Man Lu, Zhiqiang Cao, Luoan Xiong, Hongying Deng, Kangkang Ma, Ning Liu, Yanding Qin, Shen-Bo Chen, Jun-Hu Chen, Yao Li, Yijin Liu, Zhongbo Yu

Get full text

hCeO2@CA-074Me Nanoparticles Alleviate Inflammation and Improve Osteogenic Microenvironment by Regulating the CTSB-NLRP3 Signaling Pathway by Niu Z, Xia X, Zhang Z, Liu J, Li X

“…Zhaojun Niu,1,2 Xiaomin Xia,1,2 Zhimin Zhang,1 Jie Liu,1,2 Xue Li1,2 1Department of Stomatology, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, People’s Republic of China; 2School of Stomatology, Qingdao University, Qingdao, People’s Republic of ChinaCorrespondence: Jie Liu; Xue Li, Email 18661801995@163.com; lixue@qdu.edu.cnBackground: It is well established that the interaction between osteogenesis and inflammation can impact bone tissue regeneration. …”
Get full text

The pattern of genetic diversity of different breeds of pigs based on microsatellite analysis by V. R. Kharzinova, N. A. Zinovieva

“…The highest level of genetic diversity was found in the Large White breed of the Republic of Belarus (HO = 0.707 and NE = 0.702). The minimum level of genetic diversity was found in pigs of the imported breeds – the Landrace (HO = 0.459, HE = 0.400) and the Duroc (HO = 0.480, HE = 0.469) – indicating a high selection pressure in these breeds. …”
Get full text

Eco-Friendly Synthesis of Zirconium Dioxide Nanoparticles from <i>Toddalia asiatica</i>: Applications in Dye Degradation, Antioxidant and Antibacterial Activity by Arumugam Kathirvel, Ramalingam Srinivasan, Sathasivam Harini, Natarajan Ranjith, Govindan Suresh Kumar, Kesavan Lalithambigai, Raji Atchudan, Mohamed A. Habila, Ahmed M. Aljuwayid, Hae Keun Yun

Get full text

Comparative evaluation of commercial Douchi by different molds: Biogenic amines, non-volatile and volatile compounds by Aijun Li, Gang Yang, Zhirong Wang, Shenglan Liao, Muying Du, Jun Song, Jianquan Kan

Get full text

Foodborne toxin Aflatoxin B1 induced glomerular podocyte inflammation through proteolysis of RelA, downregulation of miR-9 and CXCR4/TXNIP/NLRP3 pathway by Jie Zhang, Shuang Yang, Baocai Xu, Zihui Qin, Xinyi Guo, Ben Wei, Qinghua Wu, Kamil Kuca, Tushuai Li, Wenda Wu

Get full text

Relationship Between Serum HMGB1 and RAGE Levels and Restenosis in Type 2 Diabetes Mellitus Patients Complicated With Lower Extremity Vascular Disease: A Retrospective Study by Jia T, Zhang X, Li L, Jiang X, Wang M

“…Ting Jia,&ast; Xuyan Zhang,&ast; Li Li, Xiaowan Jiang, Mengjie Wang Department of Endocrinology, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Xuyan Zhang, Department of endocrinology, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People’s Republic of China, Tel +86 027 65696337, Email Zhangxuuyan21@163.comPurpose: To investigate the potential association between the serum concentrations of high mobility group protein B1 (HMGB1) and the receptor for advanced glycation end-products (RAGE) in relation to the occurrence of restenosis following interventional therapy for lower extremity vascular disease in patients diagnosed with type 2 diabetes mellitus (T2DM).Patients and Methods: From March 2023 to January 2024, 96 T2DM patients with lower extremity vascular disease who underwent interventional therapy and 6-month follow-up in our hospital were studied. …”
Get full text

Metabolite profiling of some organs and the potential of Mukia javanica as an antihypertension by Mentari Putri Pratami, Mentari Putri Pratami, Wawan Sujarwo, Miftahul Huda Fendiyanto, Ratna Yuniati, Ifan Rizky Kurniyanto, Nuniek Widiayani, Mahmoud F. Seleiman, Nawab Ali, Muhammad Fuad Anshori

Get full text

Spatiotemporal transcriptome and scRNA sequencing analysis reveals that IKFZ1‐mediated microglia underlies a therapy for intracerebral hemorrhage by Wenqiao Qiu, Jie Tian, Gao Mou, Lili Guo, Tao Xu, Wei Liu, Jianwei Zhu, Yi Zhang, Xiaolin Hou, Yao Xie, Huan Xiong, Xinda Li, Yangyang Wang, Mingjun Gao, Anguo Wu, Longyi Chen, Jie Mei, Lulin Huang, Ruxiang Xu

Get full text

Causal Relationships Between Blood Lipid Levels and Chronic Obstructive Pulmonary Disease: A Mendelian Randomization Analysis by Huang P, Zhao Y, Wei H, Wu W, Guo Z, Ma S, Xu M, Wang Q, Jia C, Xiang T, Li H

“…Ping Huang,&ast; Yong Zhao,&ast; Haiyan Wei, Wenhui Wu, Ziwen Guo, Shiyi Ma, Meng Xu, Qin Wang, Cheng Jia, Ting Xiang, Huamao Li Department of Rehabilitation Medicine, General Hospital of Central Theater Command, Wuhan, 430065, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Huamao Li; Ting Xiang, Department of Rehabilitation Medicine, General Hospital of Central Theater Command, Wuhan, 430065, People’s Republic of China, Email 71831102@qq.com; 42254403@qq.comBackground: In preliminary research and literature review, we identified a potential link between chronic obstructive pulmonary disease (COPD) and lipid metabolism. …”
Get full text

The Northern and Southern Hemispheric Asymmetries of Mesospheric Ozone at High Latitudes During the January 2012 Solar Proton Events by Shiping Xiong, Jingyuan Li, Guanchun Wei, Jianyong Lu, Yufeng Tian, Xiaoping Zhang, Shuai Fu, Meng Sun, Zheng Li, Hua Zhang, Jingqi Cui, Shuwen Jiang, Chaolei Yang

Get full text

Lack of Male-Female Differences in Disposition and Esterase Hydrolysis of Ramipril to Ramiprilat in Healthy Volunteers after a Single Oral Dose by Tom B. Vree, Erik Dammers, Ivan Ulc, Stefan Horkovics-Kovats, Miroslav Ryska, IJsbrand Merkx

Get full text

Clinical Outcomes of Hepatic Arterial Infusion Chemotherapy Plus Lenvatinib and Tislelizumab for Treating Hepatocellular Carcinoma and Type IV Portal Vein Tumor Thrombus by Li X, Cao K, Fu Z, Chen X, Zhong J, Liu L, Ding N, Zhang X, Qu Z, Zhu L, Zhai J

“…Xiaowei Li,&ast; Kunkun Cao,&ast; Zhigang Fu,&ast; Xiaoxia Chen, Jiaming Zhong, Li Liu, Ning Ding, Xiaoli Zhang, Zengqiang Qu, Lijun Zhu, Jian Zhai Department II of Interventional Radiology, Shanghai Eastern Hepatobiliary Surgery Hospital, Shanghai, 200438, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Jian Zhai; Lijun Zhu, Department II of Interventional Radiology, Shanghai Eastern Hepatobiliary Surgery Hospital, Shanghai, 200438, People’s Republic of China, Email jianzhai1979@126.com; lijun_zhush@163.comPurpose: To assess the activity and toxicity of hepatic arterial infusion chemotherapy (HAIC)+tislelizumab+lenvatinib (HAIC+tisle+len) in hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT) type IV (Vp4 hCC) in a real-world context.Methods: Fifty-five patients, with Vp4 hCC receiving HAIC+tisle+len therapy from April 2021 to December 2022, were analyzed retrospectively. …”
Get full text

Comprehensive analysis of the 5-HTTLPR allelic polymorphism effect on behavioral and neurophysiological indicators of executive control in people from different ethnic groups in Si... by A. N. Savostyanov, D. V. Bazovkina, S. A. Lashin, S. S. Tamozhnikov, A. E. Saprygin, T. N. Astakhova, U. N. Kavai-ool, N. V. Borisova, A. G. Karpova

“…The study was conducted among people from three ethno-regional groups: healthy Caucasoids from Novosibirsk, the Mongoloid groups of the indigenous population of the Tuva Republic and Sakha Republic (Yakutia). Genetic, ethnographic, and psychological influences on an individual’s ability to control motor responses were compared. …”
Get full text

A New Nanocomposite for Inducing Demineralized Dentin Remineralization by Ban G, Long J, Yan K, Li Q, Huang X, Wei X, Xie F

“…Guifei Ban,1,2,&ast; Jindong Long,1,2,&ast; Kaiqi Yan,1,2,&ast; Qiurong Li,1,2 Xiaoman Huang,1,2 Xiaolang Wei,1,2 Fangfang Xie1,2 1College & Hospital of Stomatology, Guangxi Medical University, Nanning, Guangxi, 530021, People’s Republic of China; 2Guangxi Key Laboratory of Oral and Maxillofacial Rehabilitation and Reconstruction, College of Stomatology, Hospital of Stomatology, Guangxi Medical University, Nanning, Guangxi, China; Guangxi Health Commission Key Laboratory of Prevention and Treatment for Oral Infectious Diseases, College of Stomatology, Hospital of Stomatology, Guangxi Medical University, Nanning, Guangxi, 530021, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Fangfang Xie, Email xiedualfang@163.comObjective: This study aimed to investigate a method for promoting the remineralization of demineralized dentin collagen fibers, with the objective of enhancing the bonding strength and durability of dentin resin while reducing the incidence of secondary caries.Methods: A mineralized solution, PAMAM-COOH/ACMP-MDP ethanol solution, was prepared, consisting of the dendritic organic macromolecule PAMAM-COOH, magnesium ions, and methacryloyloxydecyl dihydrogen phosphate (MDP). …”
Get full text

Insular infraorbital neurovascular pedicle labial salivary gland transplantation for the treatment of severe dry eye disease: an IDEAL stage 0, 1 and 2a study by Jing Zhou, Xiaohong Chen, Mei Li, Ke Yang, Ying Jie, Yinghui Wang, Yingshi Piao, Yun Cheng

Get full text

New Evidence for <i>Cotinus coggygria</i> Scop. Extracts Application in Gastrointestinal Ailments by Dejan Stojković, Nina Dragičević, Marija Ivanov, Nevena Gajović, Milena Jurišević, Ivan Jovanović, Marina Tomović, Jelena Živković

Get full text

Situating the salience and parietal memory networks in the context of multiple parallel distributed networks using precision functional mapping by Young Hye Kwon, Joseph J. Salvo, Nathan L. Anderson, Donnisa Edmonds, Ania M. Holubecki, Maya Lakshman, Kwangsun Yoo, B.T. Thomas Yeo, Kendrick Kay, Caterina Gratton, Rodrigo M. Braga

Get full text

Recent advancement and design in supercapacitor hybrid electrode materials: Bridging the gap between energy and power density by Soumen Mandal, Arpit B. Mendhe, Hitesh M. Rakhade, Neha S. Barse, Mayna Roy, P. Rosaiah, Taejoon Park, Han-Seung Lee, Avinash C. Mendhe, Daewon Kim

Get full text

Efficient method for identification of Escherichia coli strains isolated from various chicken (Gallus gallus domesticus) organs by V. P. Terletskiy, V. I. Tyshchenko, O. B. Novikova, E. D. Dzhavadov, I. Ya. Shakhtamirov, N. L. Adaev

Get full text