Is platelet-rich plasma better than steroids as epidural drug of choice in lumbar disc disease with radiculopathy? Meta-analysis of randomized controlled trials by Sathish Muthu, Sathish Muthu, Sathish Muthu, Vibhu Krishnan Viswanathan, Vibhu Krishnan Viswanathan, Prakash Gangadaran, Prakash Gangadaran, Prakash Gangadaran

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Three-Dimensional Modelling of Desorbed Gas Volume and Comparison to Gas Production Rate in the Montney Plays, Western Canadian Sedimentary Basin by Gihun Song, Hyun Suk Lee, Hyundon Shin

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Comparative Efficacy of Esketamine vs Sufentanil with Propofol for Sedation in EUS: A Randomized, Controlled Study by Liu C, Wang Y, Yin Y, Wang P, Ji X, Sun J, Zhao S, Jia Y, Liu S, Zhou Z

“…Cuicui Liu,1,* Yanting Wang,1,* Yanwei Yin,2 Pei Wang,1 Xiangyu Ji,1 Jian Sun,1 Shuo Zhao,1 Yanfang Jia,1 Shanling Liu,1 Zangong Zhou1 1Daytime Anesthesiology Department, the Affiliated Hospital of Qingdao University, Qingdao, Shandong Province, People’s Republic of China; 2Pain Department, the Affiliated Hospital of Qingdao University, Qingdao, Shandong Province, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zangong Zhou, Daytime Anesthesiology Department, the Affiliated Hospital of Qingdao University, 16 Jiangsu Road, Shinan District, Qingdao, Shandong Province, 266000, People’s Republic of China, Tel +86 532-82912511, Email zhouzangong@qdu.edu.cnPurpose: This randomized, controlled trial aimed to assess the sedative effects of esketamine and sufentanil combined with propofol during EUS.Patients and Methods: Three hundred and forty patients undergone EUS were randomly divided into two groups to receive esketamine 0.25 mg/kg combined with propofol (esketamine group) or sufentanil 0.1 μg/kg combined with propofol (sufentanil group). …”
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Correlation Between Gastroesophageal Reflux Disease and Small Intestinal Bacterial Overgrowth: Analysis of Intestinal Microbiome and Metabolic Characteristics by Wang ZT, Tan WT, Huang JL, Zhang PF, Li Q, Wang MM, Meng MM, Su H, Guo CM, Liu H

“…Zi-Teng Wang,1,2,* Wen-Tao Tan,1,* Jia-Li Huang,1 Peng-Fei Zhang,3 Qian Li,1 Miao-Miao Wang,1 Ming-Ming Meng,1 Hui Su,1 Chun-Mei Guo,1 Hong Liu1 1Gastroenterology Department, Beijing Shijitan Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Gastroenterology Department, Beijing Ditan Hospital, Capital Medical University, Beijing, People’s Republic of China; 3Emergency Department, Beijing Tiantan Hospital, Capital Medical University, Beijing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hong Liu, Email liuhong_sjt@ccmu.edu.cnBackground: Our study examines the relationship between gastroesophageal reflux disease (GERD) and small intestinal bacterial overgrowth (SIBO), focusing on the potential impact of acid-suppressive drugs. …”
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The Frequency of <i>DPYD</i> c.557A>G in the Dominican Population and Its Association with African Ancestry by Mariela Guevara, Carla González de la Cruz, Fernanda Rodrigues-Soares, Ernesto Rodríguez, Caíque Manóchio, Eva Peñas-Lledó, Pedro Dorado, Adrián LLerena

“…<b>Methods:</b> For this study, 196 healthy volunteers from the Dominican Republic were genotyped for <i>DPYD</i> variants by qPCR, and individual genomic ancestry analysis was performed in 178 individuals using 90 informative ancestry markers. …”
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Corticosteroid Phobia: A Key Barrier to Treatment in Young Women with Idiopathic Granulomatous Mastitis by Lin W, Wang Q, Liu J, Tan Q

“…Weiyi Lin,1,2,&ast; Qiuzhou Wang,2,&ast; Jia Liu,1,2 Qiuwen Tan1,2 1Division of Breast Surgery, Department of General Surgery, West China Hospital, Sichuan University, Chengdu City, Sichuan Province, People’s Republic of China; 2Breast Center, West China Hospital, Sichuan University, Chengdu City, Sichuan Province, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Qiuwen Tan, Division of Breast Surgery, Department of General Surgery, West China Hospital, Sichuan University, No. 37 Guo Xue Alley, Chengdu City, Sichuan Province, 610041, People’s Republic of China, Email hxtanqiuwen@163.comPurpose: Corticosteroids are recommended as a first-line treatment for idiopathic granulomatous mastitis (IGM), a disease that usually occurs in young women. …”
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Binding of HCN channels to GABAB receptors in dopamine neurons of the VTA limits synaptic inhibition and prevents the development of anxiety by Enrique Pérez-Garci, Kateryna Pysanenko, Giorgio Rizzi, Florian Studer, Daniel Ulrich, Thorsten Fritzius, Simon Früh, Alessandra Porcu, Valérie Besseyrias, Adolf Melichar, Martin Gassmann, Tania Rinaldi Barkat, Rostislav Tureček, Kelly R. Tan, Bernhard Bettler

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Clinical and molecular response to alpha1‐oleate treatment in patients with bladder cancer by Farhan Haq, Samudra Sabari, Jaromir Háček, Antonín Brisuda, Ines Ambite, Michele Cavalera, Parisa Esmaeili, Murphy Lam Yim Wan, Shahram Ahmadi, Marek Babjuk, Catharina Svanborg

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Changes in and Potential Mechanisms of Circulating IgA+CD27-Class-Switched Memory B Cells in Patients With Allergic Rhinitis by Zheng H, Xu S, Yang R, Jiao WE, Qiao YL, Liu JY, Fan HM, Zhou YT, Ni HF, Chen J, Deng YQ, Chen SM

“…Han Zheng,1,&ast; Shan Xu,1,&ast; Rui Yang,1,&ast; Wo-Er Jiao,1 Yue-Long Qiao,1,2 Jia-Yu Liu,1 Hui-Ming Fan,1 Yan-Ting Zhou,1 Hai-Feng Ni,3 Jin Chen,1 Yu-Qin Deng,1 Shi-Ming Chen1 1Department of Otolaryngology-Head and Neck Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, People’s Republic of China; 2Swiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland; 3Department of Otolaryngology-Head and Neck Surgery, Zhejiang Hospital, Hangzhou, Zhejiang, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Yu-Qin Deng; Shi-Ming Chen, Department of Otolaryngology-Head and Neck Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, People’s Republic of China, Email bamboo0723@126.com; shimingchen0468@163.comBackground: The role of memory B cells and their subgroups in allergic rhinitis (AR) and allergen immunotherapy (AIT) remains unclear. …”
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Correlation Between Inflammatory Markers and Pathogenic Bacteria in Children&rsquo;s Winter Respiratory Infections in Xinjiang by Wang L, Wang W, Wang J, Zhu L, Luo J

“…Lixia Wang,1,&ast; Wei Wang,2,&ast; Jian Wang,1 Ling Zhu,1 Jianjiang Luo1 1Department of Respiratory and Critical Care Medical Department Infectious Diseases Ward, The Traditional Chinese Medicine Hospital Affiliated to Xinjiang Medical University, Urumqi, Xinjiang, People’s Republic of China; 2Department of Respiratory and Critical Care Medicine, Affiliated Traditional Chinese Medicine Hospital of Xinjiang Medical University, Urumqi, Xinjiang, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Jianjiang Luo, Department of Respiratory and Critical Care Medical Department infectious diseases Ward, The Traditional Chinese Medicine Hospital Affiliated to Xinjiang Medical University, No. 116 Huanghe Road, Shayibake District, Urumqi, Xinjiang, People’s Republic of China, Tel +86013999946655, Email ljj.781201@163.comBackground: This study examines the distribution characteristics of pathogenic bacteria in respiratory infections and their relationship with inflammatory markers to guide clinical drug use.Methods: We selected 120 patients with lower respiratory tract infection in the electronic medical record system of Xinjiang Provincial People’s Hospital from March 2019 to March 2023 for a case-control study. …”
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Lysozyme-based spray for treatment of radiotherapy-induced oral mucositis by Zdenka Gojković, Jelena Rožić, Nataša Gašpar, Aziz Šukalo, Meliha Mehić, Amna Tanović Avdić, Una Glamočlija

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Development of improved deep learning models for multi-step ahead forecasting of daily river water temperature by Mehdi Gheisari, Jana Shafi, Saeed Kosari, Samaneh Amanabadi, Saeid Mehdizadeh, Christian Fernandez Campusano, Hemn Barzan Abdalla

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Evaluation of the Effectiveness of Standard Precaution Training on Disposition of Occupational Blood Exposure Among Healthcare Trainees: A Pre-Post Intervention Study by Zhang X, Li H, Li N, Li Y, Kong L, Zhang M, Wang P, Ma Y, Ni L, Liu L, Meng X

“…Xing Zhang,1 Hongwei Li,2 Ning Li,1 Yusen Li,1 Li Kong,1 Min Zhang,1 Peng Wang,1 Yonghui Ma,1 Leiping Ni,2 Lili Liu,1 Xiujuan Meng1 1Healthcare-Associated Infection Control Department, Affiliated Hospital of Jining Medical University, Jining, Shandong, People’s Republic of China; 2Medical Education Center, Affiliated Hospital of Jining Medical University, Jining, Shandong, People’s Republic of ChinaCorrespondence: Xiujuan Meng, Healthcare-associated infection control department, Affiliated Hospital of Jining Medical University, Jining, Shandong, People’s Republic of China, Tel +86 537 2903180, Fax +86 537 2213030, Email mxj0324@163.comIntroduction: Blood-borne occupational exposure (OBE) is one of the major public health problem for healthcare workers globally. …”
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Lifecycle environmental benefits of integrated rational fertilization, biochar, and constructed wetland in mitigating nutrient loading by Yu-Ning Chen, Chihhao Fan, Michal Šereš, Markéta Šerešová, Jan Vymazal, Shu-Yuan Pan

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The impact of urban air pollution on human health by N. Komilova, K. Egamkulov, M. Hamroyev, K. Khalilova, D. Zaynutdinova

“…The study analysed the indicators of emissions of pollutants into the atmosphere in the Republic of Uzbekistan as a whole and by regions. Furthermore, the paper provides a detailed analysis of the general morbidity of the population of the Republic of Uzbekistan and indicators of the incidence of cardiovascular diseases, based on which a correlation and regression analysis was performed. …”
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Pharmacokinetics and Bioequivalence of Two Fixed-Dose Combination Tablets of Valsartan/Amlodipine (80/5 Mg) in Healthy Chinese Subjects by Tian M, Huang J, Chen Y, Jin Q, Jiang H, Shi C, Mei J, Xu M, Yu X, Yang S

“…Mengli Tian,1 Jinlong Huang,2 Yingrong Chen,1 Qiuyue Jin,1 Hong Jiang,2 Cunyuan Shi,2 Jue Mei,1 Min Xu,1 Xiang Yu,1 Shuixin Yang1 1Clinical Trial Center, Huzhou Central Hospital, Fifth School of Clinical Medicine of Zhejiang Chinese Medical University, Huzhou, 313000, People’s Republic of China; 2Zhejiang Jianfeng Pharmaceutical Co Ltd., Jinhua, 321025, People’s Republic of ChinaCorrespondence: Shuixin Yang, Clinical Trial Center, Huzhou Central Hospital, Fifth School of Clinical Medicine of Zhejiang Chinese Medical University, 1558, North Third Ring Road, Huzhou, 313000, People’s Republic of China, Tel +86-0572-2978254, Email ysx@hzhospital.comPurpose: The study aimed to investigate the pharmacokinetics and bioequivalence of coformulations of valsartan and amlodipine in healthy Chinese subjects under both fasting and fed conditions.Methods: The research was conducted under both fasting and fed studies and employed a single-center, randomized, open-label, single-dose, three-period design with partial-repeat and crossover elements. …”
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The Prognostic Significance of the CALLY Index in Ampullary Carcinoma: An Inflammation-Nutrition Retrospective Analysis by Xi P, Huang G, Huang K, Qin D, Yao Z, Jiang L, Zhu Q, He C

“…Pu Xi,1,&ast; Guizhong Huang,1,&ast; Kewei Huang,2,&ast; Dailei Qin,1 Zehui Yao,1 Lingmin Jiang,1 Qi Zhu,1 Chaobin He1 1Department of Pancreatobiliary Surgery, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, People’s Republic of China; 2State Key Laboratory of Oncology in South China, Department of Clinical Laboratory, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Chaobin He, Department of Pancreatobiliary Surgery, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, 651 Dongfeng Road E, Guangzhou, Guangdong, 510060, People’s Republic of China, Email hechb@sysucc.org.cnBackground: As a novel inflammatory-nutritional biomarker, the C-reactive protein–albumin–lymphocyte (CALLY) index has demonstrated significant prognostic value in various malignancies. …”
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Prevalence and factors associated with burnout among healthcare providers at Kasulu district in Kigoma region, 2024: an analytical cross-sectional study in a primary healthcare set... by Omary Ubuguyu, Godbless Henry Mfuru, Khadija I Yahya-Malima

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Tanshinone I Ameliorates Psoriasis-Like Dermatitis by Suppressing Inflammation and Regulating Keratinocyte Differentiation by Wang Q, Luo X, Su Y, Jin Y, Kuang Q, Li S, Shen W, Zhu Y

“…Qiao Wang,1,&ast; Xin Luo,1,&ast; Yuwen Su,1 Yi Jin,1 Qiqi Kuang,1 Siying Li,1 Weiyun Shen,2 Yanshan Zhu1 1Department of Dermatology, Second Xiangya Hospital, Hunan Key Laboratory of Medical Epigenomics, Clinical Medical Research Center of Major Skin Diseases and Skin Health of Hunan Province, Central South University, Changsha, Hunan, People’s Republic of China; 2Department of Anesthesiology, Second Xiangya Hospital, Anesthesiology Research Institute of Central South University, Changsha, Hunan, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Xin Luo; Yanshan Zhu, Department of Dermatology, Second Xiangya Hospital, Hunan Key Laboratory of Medical Epigenomics, Clinical Medical Research Center of Major Skin Diseases and Skin Health of Hunan Province, Central South University, 139 Renmin Middle Road, Changsha, Hunan, People’s Republic of China, Email 248201037@csu.edu.cn; 218202091@csu.edu.cnBackground: Psoriasis is an immune-related inflammatory systemic condition characterized by dysregulated keratinocyte proliferation and chronic inflammation. …”
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Association of Depression with Age at Natural Menopause: A Cross-Sectional Analysis with NHANES Data by An S, Ren S, Ma J, Zhang Y

“…Shuaiqi An,1,&ast; Shiyan Ren,1,&ast; Jiawen Ma,1 Yizhou Zhang1,2 1School of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, People’s Republic of China; 2Zhejiang Famous Chinese Medicine Clinic, the Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Yizhou Zhang, School of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, People’s Republic of China, Email zhangyizhou2005@126.comPurpose: To evaluate the association between depression and age of natural menopause in American women.Patients and Methods: This cross-sectional study utilized eight cycles of the National Health and Nutrition Examination Survey (NHANES) conducted from 2005 to 2023. …”
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