Inflammation and Immune Escape in Ovarian Cancer: Pathways and Therapeutic Opportunities by Liu C, Yin Q, Wu Z, Li W, Huang J, Chen B, Yang Y, Zheng X, Zeng L, Wang J

“…Chunyan Liu,1,* Qinan Yin,2,3,* Zhaoying Wu,1 Wenhui Li,1 Jun Huang,1 Bo Chen,1 Yanjun Yang,1 Xuewei Zheng,3 Li Zeng,3 Jingjing Wang3 1Department of Obstetrics and Gynecology, China-Japan Friendship Hospital, Beijing, People’s Republic of China; 2Department of Radiation Oncology, First Affiliated Hospital, College of Clinical Medicine, Henan University of Science and Technology, Luoyang, People’s Republic of China; 3Precision Medicine Laboratory, School of Medical Technology and Engineering, Henan University of Science and Technology, Luoyang, People’s Republic of China*These authors contributed equally to this workCorrespondence: Chunyan Liu, Department of Obstetrics and Gynecology, China-Japan Friendship Hospital, No. 2 Yinghua Dongjie, Chaoyang District, Beijing, 100029, People’s Republic of China, Email juneliu2022@126.comAbstract: Ovarian cancer (OC) remains one of the most lethal gynecological malignancies, largely due to its late-stage diagnosis and high recurrence rates. …”
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Simultaneous Anti-Tuberculosis and Anti-Tumor Treatment with Immune Checkpoint Inhibitors for Co-Existent Pulmonary Tuberculosis and Advanced Lung Cancer by Wang H, Gao L, Cai X, Li J, Lang Y, Zheng R, Yang S

“…Huaichong Wang,1 Liujie Gao,2 Xinjun Cai,1 Jinmeng Li,1 Yuying Lang,1 Ren Zheng,1 Shengya Yang3 1Department of Pharmacy, Hangzhou Red Cross Hospital, Hangzhou, Zhejiang Province, People’s Republic of China; 2Department of Oncology, Hangzhou Red Cross Hospital, Hangzhou, Zhejiang Province, People’s Republic of China; 3Tuberculosis Diagnosis and Treatment Center, Hangzhou Red Cross Hospital, Hangzhou, Zhejiang Province, People’s Republic of ChinaCorrespondence: Shengya Yang, Tuberculosis Diagnosis and Treatment Center, Hangzhou Red Cross Hospital, East Huancheng Road No. 208, Hangzhou, Zhejiang Province, People’s Republic of China, Email 15967116949@163.comBackground: Immune checkpoint inhibitors (ICIs) have emerged as the first-line treatment for driver-negative advanced non-small cell lung cancer (NSCLC). …”
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Systemic Immune-Inflammation Index: A Promising, Non-Invasive Biomarker for Crohn’s Disease Activity and Severity Assessment by Deng Y, Fu T, Gao D, Zhou J, Nie X, Wang F, Yu Q

“…Yu’en Deng,1,2 Ting Fu,1 Dian Gao,3 Jianming Zhou,1 Xinhua Nie,1 Fenfen Wang,1 Qiongfang Yu1 1Department of Gastroenterology and Hepatology, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330006, People’s Republic of China; 2Huankui Academy, Jiangxi Medical College, Nanchang University, Nanchang, 330031, People’s Republic of China; 3Department of Pathogen Biology and Immunology, Jiangxi Medical College, Nanchang University, Nanchang, 330006, People’s Republic of ChinaCorrespondence: Qiongfang Yu, Department of Gastroenterology and Hepatology, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Minde Road 1, Nanchang, 330006, People’s Republic of China, Email qiongfangyu@yeah.netPurpose: Crohn’s disease (CD) is a chronic inflammatory disorder with periods of exacerbation and remission. …”
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Impact of Herpesvirus Detection via Metagenomic Next-Generation Sequencing in Patients with Lower Respiratory Tract Infections by Zhang H, Zhang X, Zheng Y, Gu X, Fu Z, Gai W, Wang H

“…Huihui Zhang,1,* Xiaojing Zhang,2,* Yafeng Zheng,2,* Xiao Gu,1 Zhongming Fu,1 Wei Gai,2 Huaying Wang1 1Department of Respiratory and Critical Care Medicine, The Affiliated People’s Hospital of Ningbo University, Yinzhou People’s Hospital, Ningbo, Zhejiang, 315040, People’s Republic of China; 2WillingMed Technology (Beijing) Co., Ltd, Beijing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Wei Gai, WillingMed Technology (Beijing) Co., Ltd, No. 156 Jinghai 4th Road, Beijing Economic and Technological Development Zone, Beijing, 101103, People’s Republic of China, Email weigai@willingmed.com Huaying Wang, The Affiliated People’s Hospital of Ningbo University, Yinzhou People’s Hospital, No. 251, Baizhang East Road, Ningbo, 315040, People’s Republic of China, Email yingmeire@163.comPurpose: This study aimed to investigate the impact of herpesvirus detection by metagenomic next-generation sequencing (mNGS) of bronchoalveolar lavage fluid (BALF) on lower respiratory tract infections (LRTIs) patients’ lung microbiome composition and prognosis.Patients and methods: We initially enrolled 234 hospitalized patients with LRTIs who underwent BALF mNGS between February 2022 and May 2023. …”
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Analysis of Factors Related to Pulmonary Nodules in Patients With Fatty Liver: A Large-Scale Cohort Study Based on a Physical Examination Population by Qin Y, Huang X, Lin J, Pan L, Liang Q, Li W

“…Yan Qin,1,* Xiaozhi Huang,1,* Jiali Lin,2,* Liuxian Pan,1,* Qiuyu Liang,2 Wei Li1 1Health Management Center, People’s Hospital of Guangxi Zhuang Autonomous Region and Guangxi Academy of Medical Sciences, Nanning, People’s Republic of China; 2Health Management Research Institute, People’s Hospital of Guangxi Zhuang Autonomous Region and Guangxi Academy of Medical Sciences, Nanning, People’s Republic of China*These authors contributed equally to this workCorrespondence: Wei Li, Health Management Center, People’s Hospital of Guangxi Zhuang Autonomous Region and Guangxi Academy of Medical Sciences, Nanning, Guangxi, 530021, People’s Republic of China, Email lw6666gx@aliyun.com Qiuyu Liang, Health Management Research Institute, People’s Hospital of Guangxi Zhuang Autonomous Region and Guangxi Academy of Medical Sciences, Nanning, Guangxi, 530021, People’s Republic of China, Email liang_qiu_yu@foxmail.comPurpose: People with fatty liver are at high risk for pulmonary nodules, but the underlying mechanism is unclear. …”
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A Multidisciplinary-Based and Bundle Intervention for Controlling Carbapenem-Resistant Organisms in Neurosurgery by Zhu W, Liang Y, Xu J, Weng C

“…Wen Zhu,1 Yi Liang,2 Jie Xu,3 Chao Weng1 1Department of Hospital Infection Control, Shidong Hospital, Yangpu District, Shidong Hospital Affiliated to University of Shanghai for Science and Technology, Shanghai, 200438, People’s Republic of China; 2Department of Clinical Laboratory, Shidong Hospital, Yangpu District, Shidong Hospital Affiliated to University of Shanghai for Science and Technology, Shanghai, 200438, People’s Republic of China; 3Department of Neurosurgery, Shidong Hospital, Yangpu District, Shidong Hospital Affiliated to University of Shanghai for Science and Technology, Shanghai, 200438, People’s Republic of ChinaCorrespondence: Chao Weng, Department of Hospital Infection Control, Shidong Hospital, 999 Shiguang Road, Shanghai, 200438, People’s Republic of China, Email 191156421@qq.comPurpose: Carbapenem-resistant organisms (CROs) have been listed as the primary risk resistance bacteria due to their high detection rates and extensive drug resistance. …”
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Jiangzhi Granule Ameliorates JNK-Mediated Mitochondrial Dysfunction to Reduce Lipotoxic Liver Injury in NASH by Jiang Y, Xu J, Ding J, Liu T, Liu Y, Huang P, Wang Q, Zheng P, Song H, Yang L

“…Yuwei Jiang,1,* Jiaoya Xu,1,2,* Junyao Ding,1,* Tao Liu,1 Yang Liu,1,3 Ping Huang,1 Qianlei Wang,1 Peiyong Zheng,1 Haiyan Song,1 Lili Yang1 1Institute of Digestive Diseases, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China; 2Department of Gout, Guanghua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China; 3Teaching Experiment Center, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China*These authors contributed equally to this workCorrespondence: Haiyan Song; Lili Yang, Institute of Digestive Diseases, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, 725 South Wanping Road, Shanghai, 200032, People’s Republic of China, Email songhy@126.com; yanglili76@126.comPurpose: Mitochondrial dysfunction mediated by c-Jun N-terminal kinase (JNK) plays an important role in lipotoxic liver injury in nonalcoholic steatohepatitis (NASH). …”
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Blood Lipid Levels and Their Value as Markers of Disease Activity in Severe Ulcerative Colitis by Zhu L, Tian L, Li S, Huo L

“…Lingling Zhu,1– 3 Linglin Tian,3 Suxia Li,1 Lijuan Huo3 1First Clinical Medical College, Shanxi Medical University, Taiyuan, Shanxi, People’s Republic of China; 2Linfen Vocational and Technical College, Linfen, Shanxi, People’s Republic of China; 3Department of Gastroenterology, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, People’s Republic of ChinaCorrespondence: Lijuan Huo, Department of Gastroenterology, First Hospital of Shanxi Medical University, 85 Jiefang South Road, Taiyuan, 030001, Shanxi, People’s Republic of China, Tel +86-13835107953, Email mymail5296@163.comPurpose: There is limited research on the correlation between blood lipid levels and severe ulcerative colitis, and this article helps to reveal the relationship between the two. …”
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The Expression of T Cell FOXP3 and T-Bet Is Upregulated in Severe but Not Euthyroid Hashimoto’s Thyroiditis by Stana Tokić, Mario Štefanić, Ljubica Glavaš-Obrovac, Sonja Jaman, Eva Novosadová, Jana Petrkova, Zdenka Navratilova, Mirjana Suver Stević, Martin Petrek

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Family Support Moderates the Relationship Between Pregnancy Stress, Depressive Symptoms, and Insomnia by Liu S, Huang M, Zhang F, Tao J, Wen D, Deng W, Lin Y, Zhang P, Li M

“…ShanYan Liu,1 Meijiao Huang,2 FengYing Zhang,2 Jing Tao,1 Dan Wen,1 WeiYuan Deng,1 YaoHua Lin,3 Ping Zhang,2 Min Li2 1The Affiliated Nanhua Hospital, Department of Obstetrics, Hengyang Medical College, University of South China, Hengyang, Hunan, 421002, People’s Republic of China; 2The Affiliated Nanhua Hospital, Department of Neurology, Hengyang Medical College, University of South China, Hengyang, Hunan, 421002, People’s Republic of China; 3The First Affiliated Hospital, Institute of Obstetrics, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, People’s Republic of ChinaCorrespondence: Ping Zhang; Min Li, The Affiliated Nanhua Hospital, Department of Neurology, Hengyang Medical College, University of South China, Hengyang, Hunan, 421002, People’s Republic of China, Email 516387382@qq.com; lim-usc@qq.comObjective: Insomnia is a common issue that pregnant women often have to deal with. …”
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3D Localization of FRB 20190425A for Its Potential Host Galaxy and Implications by Da-Chun Qiang, Zhi-Qiang You, Sheng Yang, Zong-Hong Zhu, Ting-Wan Chen

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The Investigation of the Relationship Between Individual Pain Perception, Brain Electrical Activity, and Facial Expression Based on Combined EEG and Facial EMG Analysis by Ma C, Wang C, Zhu D, Chen M, Zhang M, He J

“…Chaozong Ma,1,2,* Chenxi Wang,3,* Dan Zhu,1 Mingfang Chen,1 Ming Zhang,1,4 Juan He1 1Department of Rehabilitation Medicine, First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, People’s Republic of China; 2Military Medical Psychology School, Fourth Military Medical University, Xi’an, People’s Republic of China; 3Center for Brain Imaging, School of Life Science and Technology, Xidian University, Xi’an, People’s Republic of China; 4Department of Medical Imaging, First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, People’s Republic of China*These authors contributed equally to this workCorrespondence: Ming Zhang; Juan He, Email zhangming01@mail.xjtu.edu.cn; hejuan198553@126.comPurpose: Pain is a multidimensional, unpleasant emotional and sensory experience, and accurately assessing its intensity is crucial for effective management. …”
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Influence of single-pass caliber rolling on the microstructural evolution and mechanical properties of Mg10Gd binary alloy by H. Yu, Z.K. Liu, Y. Liu, W. Yu, Y.L. Xu, C. Liu, B.A. Jiang, S.H. Park, K.S. Shin

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Health Literacy, Label Comprehension, and Consumer Perceptions of Quasi-Drug Information Among Korean Adults: A Cross-Sectional Study by Ko Y, Kim HJ, Lee SM

“…Youngill Ko,1,2,* Heui Jae Kim,3,* Seung-Mi Lee1 1College of Pharmacy, Daegu Catholic University, Gyeongsan, Republic of Korea; 2The Gyeongbuk Pharmaceutical Association, Gumi, Republic of Korea; 3Pharmacy Department, Daehang Hospital, Seoul, Republic of Korea*These authors contributed equally to this workCorrespondence: Seung-Mi Lee, College of Pharmacy, Daegu Catholic University, 13-13 hayang-ro, Hayang-eup, Gyeongsan, 38430, Republic of Korea, Email seungmi2011@gmail.comPurpose: Health literacy (HL) is crucial in understanding labels of healthcare products. …”
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Role of Huangqin Qingre Chubi Capsule in the Reduction of the Risk of Re-Admission in Patients With Ankylosing Spondylitis: A Cohort Study by Qi Y, Liu J, Chen Y, Hu Y, Zhou Q, Huang D, Cong C, Li Y

“…Yajun Qi,1– 3 Jian Liu,1,3 Yiming Chen,1,3 Yuedi Hu,1,3 Qiao Zhou,1,3 Dan Huang,1,3 Chengzhi Cong,1,3 Yang Li1,3 1The First College of Clinical Medicine, Anhui University of Chinese Medicine, Hefei, Anhui Province, 230031, People’s Republic of China; 2College of Acupuncture and Massage, Anhui University of Chinese Medicine, Hefei, Anhui Province, 230012, People’s Republic of China; 3Department of Rheumatology and Immunology, The First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, Anhui Province, 230031, People’s Republic of ChinaCorrespondence: Jian Liu, Department of Rheumatology and Immunology, The First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, Anhui Province, 230031, People’s Republic of China, Email liujianahzy@126.comObjective: This study evaluates whether Huangqin Qingre Chubi Capsule (HQC), a traditional Chinese medicine (TCM) compound, is associated with the risk of re-admission in patients with ankylosing spondylitis (AS).Methods: In this study, we retrospectively collected the clinical data of 1,296 AS patients. …”
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Clinical Characteristics of Inpatients with Diabetic Foot Ulcer Admitted with Non-Ulcer Complaints: A Retrospective Study by Li L, Li Y, Qin S, Zeng J, Ma W, Wei D

“…Lan Li,1,2 Yue Li,2,3 Shuang Qin,2 Jing Zeng,2 Wanxia Ma,2 Dong Wei2 1Medical Examination Center, Chengdu Second People’s Hospital, Chengdu, 610017, People’s Republic of China; 2Department of Endocrinology and Metabolism, Diabetic Foot Care Center, Chengdu Second People’s Hospital, Chengdu, 610017, People’s Republic of China; 3Department of Clinical Medicine, Chengdu Medical College, Chengdu, 610500, People’s Republic of ChinaCorrespondence: Dong Wei, Department of Endocrinology and Metabolism, Diabetic Foot Care Center, The Chengdu Second People’s Hospital, Chengdu, Sichuan, 610017, People’s Republic of China, Tel/Fax +86 02867830801, Email weidong314@126.comBackground: Diabetic foot ulcer (DFU) inpatients admitted with non-ulcer complaints constitute a neglected group that might suffer from more non-standard treatments. …”
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Impact of A1 segment asymmetry on hemodynamic conditions around the circle of Willis and anterior communicating artery aneurysm formation by Joonho Lee, Seul-Ki Jeong, Ji Man Hong, Ji Man Hong

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Predicting Outcomes in Esophageal Squamous Cell Carcinoma Using scRNA‐Seq and Bulk RNA‐Seq: A Model Development and Validation Study by Jiaqi Zhang, Shunzhe Song, Yuqing Li, Aixia Gong

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Clinical Efficacy of Three-Dimensional-Printed Pure Titanium Fracture Plates with Locking Screw Systems in Distal Tibia Fractures by Ji Hye Choi, Jun Hyoung Lee, Seung Hyeop Lee, Woo Young Jang

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Deep Learning for Discrimination of Early Spinal Tuberculosis from Acute Osteoporotic Vertebral Fracture on CT by Liu W, Wang J, Lei Y, Liu P, Han Z, Wang S, Liu B

“…Wenjun Liu,1 Jin Wang,2 Yiting Lei,1 Peng Liu,3 Zhenghan Han,1 Shichu Wang,1 Bo Liu1 1Department of Orthopedics, First Affiliated Hospital, Chongqing Medical University, Chongqing, People’s Republic of China; 2College of Medical Informatics, Chongqing Medical University, Chongqing, People’s Republic of China; 3Department of Orthopedics, Daping Hospital, Army Medical University, Chongqing, People’s Republic of ChinaCorrespondence: Bo Liu, Department of Orthopedics, First Affiliated Hospital, Chongqing Medical University, Chongqing, People’s Republic of China, Tel +8613996065698, Email boliu@hospital.cqmu.edu.cnBackground: Early differentiation between spinal tuberculosis (STB) and acute osteoporotic vertebral compression fracture (OVCF) is crucial for determining the appropriate clinical management and treatment pathway, thereby significantly impacting patient outcomes.Objective: To evaluate the efficacy of deep learning (DL) models using reconstructed sagittal CT images in the differentiation of early STB from acute OVCF, with the aim of enhancing diagnostic precision, reducing reliance on MRI and biopsies, and minimizing the risks of misdiagnosis.Methods: Data were collected from 373 patients, with 302 patients recruited from a university-affiliated hospital serving as the training and internal validation sets, and an additional 71 patients from another university-affiliated hospital serving as the external validation set. …”
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