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Symptom Network and Subgroup Analysis in Patients with Exacerbation of Chronic Obstructive Pulmonary Disease: A Cross-Sectional Study
Published 2025-01-01“…Chunchun Yu,1 Mengying Xu,1 Xinyue Pang,2 Yuting Zhang,3 Xinmei Cao,2 Yixin Xu,1 Shuai Huang,1 Hongjun Zhao,4 Chengshui Chen1,3,4 1Key Laboratory of Interventional Pulmonology of Zhejiang Province, Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, People’s Republic of China; 2Zhejiang Province, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, People’s Republic of China; 3Cixi Biomedical Research Institute, Wenzhou Medical University, Wenzhou, Zhejiang, 315302, People’s Republic of China; 4Zhejiang Province Engineering Research Center for Endoscope Instruments and Technology Development, Department of Pulmonary and Critical Care Medicine, Quzhou People’s Hospital, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou, 324000, People’s Republic of ChinaCorrespondence: Hongjun Zhao; Chengshui Chen, Zhejiang Province Engineering Research Center for Endoscope Instruments and Technology Development, Department of Pulmonary and Critical Care Medicine, Quzhou People’s Hospital, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou, 324000, People’s Republic of China, Email zhaohongjun@wmu.edu.cn; chenchengshui@wmu.edu.cnPurpose: This study aims to construct a contemporaneous symptom network of inpatients with Exacerbation of Chronic Obstructive Pulmonary Disease (ECOPD) based on the symptom cluster, identify core and bridge symptoms, and patient subgroups with different symptom clusters based on individual differences in the intensity of patient symptom experiences.Patients and Methods: This study used convenience sampling to collect demographic, symptom, auxiliary examination, and prognosis information of 208 inpatients with ECOPD from April 2022 to October 2023. …”
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The e-STROKE Study: The Design of a Prospective Observational Multicentral Study
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3805
In-Situ Electrospinning Dressings Loaded with Kaempferol for Reducing MMP9 to Promote Diabetic Ulcer Healing
Published 2025-01-01“…Jianwen Li,1,2,* Hongqi Meng,3,* Wenlai Guo,3 Lubin Zhou,4 Siyu Wu,3 Guanghui Gao,4 Quanzhe Liu,3 Di You,5 Wenrui Qu2,3 1Gastroenteric Medicine and Digestive Endoscopy Center, the Second Hospital of Jilin University, Changchun, 130041, People’s Republic of China; 2Joint International Research Laboratory of Ageing Active Strategy and Bionic Health in Northeast Asia of Ministry of Education, Changchun, 130041, People’s Republic of China; 3Department of Hand Surgery, the Second Hospital of Jilin University, Changchun, 130041, People’s Republic of China; 4Polymeric and Soft Materials Laboratory, Advanced Institute of Materials Science, School of Chemical Engineering, Changchun University of Technology, Changchun, 130012, People’s Republic of China; 5Department of Anesthesiology, China-Japan Union Hospital of Jilin University, Changchun, 130012, People’s Republic of China*These authors contributed equally to this workCorrespondence: Di You; Guanghui Gao, Email youdi1118@jlu.edu.cn; ghgao@ccut.edu.cnBackground: Diabetic foot ulcers (DFUs) are often associated with persistent inflammatory response, impaired macrophage polarization, and slow vascular regeneration. …”
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Gedunin Mitigates <i>Cutibacterium acnes</i>-Induced Skin Inflammation by Inhibiting the NF-κB Pathway
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Assessment of Tumor Burden Score as a Feasible and Reliable Tool for Prognosis Prediction for Hepatocellular Carcinoma Undergoing Hepatectomy: A Multicenter, Retrospective Study
Published 2025-02-01“…Renguo Guan,1– 4,* Zehao Zheng,2– 4,* Min Deng,5,* Jie Mei,2– 4 Ye Lin1 1Department of General Surgery, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, People’s Republic of China; 2Department of Hepatobiliary Oncology, Sun Yat-sen University Cancer Center, Guangzhou, People’s Republic of China; 3State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, People’s Republic of China; 4Guangdong Provincial Clinical Research Center for Cancer, Guangzhou, People’s Republic of China; 5Department of General Surgery, The Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen, People’s Republic of China*These authors contributed equally to this workCorrespondence: Ye Lin, Email linye@gdph.org.cn; Jie Mei, Email meijie@sysucc.org.cnBackground: Maximum diameter and number are the main parameters of tumor burden in hepatocellular carcinoma (HCC). …”
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Characterization of Probiotic Abilities of Lactobacilli Isolated from Iranian Koozeh Traditional Cheese
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Increased Co-Expression of PD-L1 and CTLA-4 Predicts Poor Overall Survival in Patients with Acute Myeloid Leukemia Following Allogeneic Hematopoietic Stem Cell Transplantation
Published 2025-01-01“…Cunte Chen,1,2,* Kangjie Qiu,2,* Jie Chen,3,* Shunqing Wang,1 Yuping Zhang,1 Caixia Wang,1 Yangqiu Li2 1Department of Hematology, Guangzhou First People’s Hospital, Institute of Blood Transfusion and Hematology, Guangzhou Medical University, Guangzhou, 510180, People’s Republic of China; 2Institute of Hematology, School of Medicine, Key Laboratory for Regenerative Medicine of Ministry of Education, Jinan University, Guangzhou, People’s Republic of China; 3Department of Hematology, First Affiliated Hospital, Jinan University, Guangzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yangqiu Li, Institute of Hematology, School of Medicine, Key Laboratory for Regenerative Medicine of Ministry of Education, Jinan University, Guangzhou, 510632, People’s Republic of China, Email yangqiuli@hotmail.com Caixia Wang, Department of Hematology, Guangzhou First People’s Hospital, Institute of Blood Transfusion and Hematology, Guangzhou Medical University, Guangzhou, 510180, People’s Republic of China, Email wangcx225@163.comPurpose: Our previous study has demonstrated that high expression of immune checkpoints (ICs) was significantly associated with adverse clinical outcomes in patients with acute myeloid leukemia (AML). …”
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Construction of a Novel Necroptosis-Related Signature in Rat DRG for Neuropathic Pain
Published 2025-01-01“…Yang Liu,1 Shikang Hao,2 Hongyu Hao,3 Guona Zheng,1 Jie Bing,1 Lin Kang,1 Jia Li,4 Huanfen Zhao,1,* Han Hao5,* 1Department of Pathology, Hebei General Hospital, Shijiazhuang, People’s Republic of China; 2The First Clinical Medical School, Shanxi Medical University, Taiyuan, People’s Republic of China; 3Department of Neurology, Hebei General Hospital, Shijiazhuang, People’s Republic of China; 4Outpatient Department, Hebei Medical University, Shijiazhuang, People’s Republic of China; 5Department of Pharmacology, The Key Laboratory of Neural and Vascular Biology, Ministry of Education, The Key Laboratory of New Drug Pharmacology and Toxicology, Center of Innovative Drug Research and Evaluation, Hebei Medical University, Shijiazhuang, People’s Republic of China*These authors contributed equally to this workCorrespondence: Han Hao; Huanfen Zhao, Email 18800790@hebmu.edu.cn; ZHAO552588@126.comBackground: Recent studies have shown necroptosis may play a role in the development of inflammation-associated pain. …”
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The Timing and Spectral Properties of the 2022 Outburst of SGR J1935+2154 Observed with NICER
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Giant Granular Cell Tumor of the Left Thigh, a Rare Case Report and Literature Review
Published 2025-01-01“…Qian Liu,1,* Xiangyu Kong,2,* Jun Yang,3 Dongdong Zhang1 1Department of Oncology, Xiangyang No. 1 People’s Hospital, Hubei University of Medicine, Xiangyang, 441000, People’s Republic of China; 2Department of Radiology, Xiangyang No. 1 People’s Hospital, Hubei University of Medicine, Xiangyang, 441000, People’s Republic of China; 3Department of Neurology, Xiangyang No. 1 People’s Hospital, Hubei University of Medicine, Xiangyang, 441000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jun Yang, Department of Neurology, Xiangyang No. 1 People’s Hospital, Hubei University of Medicine, Xiangyang, 441000, People’s Republic of China, Email 296051103@qq.com Dongdong Zhang, Department of Oncology, Xiangyang No. 1 People’s Hospital, Hubei University of Medicine, Jiefang Road No. 15, Xiangyang, Hubei, 441000, People’s Republic of China, Tel +8615072278600, Email zhangdongdong@whu.edu.cnBackground: Granular cell tumor (GCT) is a rare soft tissue tumor characterized by Schwann cell differentiation. …”
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Dose-Weighted Network Pharmacology: Evaluating Traditional Chinese Medicine Formulations for Lumbar Disc Herniation
Published 2025-01-01“…Changwen Zhou,1 Ting Xiang,2 Yu Yu,3 Hongzhong Ma,1 Ce Liu,1 Feng Yang,1,4,* Lixue Yang1,4,* 1The First Clinical Medical College, Shaanxi University of Chinese Medicine, Shaanxi, People’s Republic of China; 2Rehabilitation Department, Xiang Xi Autonomous Prefecture National Hospital, Hunan, People’s Republic of China; 3Department of Chinese Medicine, Minda Hospital of Hubei Minzu University, Hubei, People’s Republic of China; 4Department of Orthopedic Hospital, The Affiliated Hospital of Shaanxi University of Chinese Medicine, Shaanxi, People’s Republic of China*These authors contributed equally to this workCorrespondence: Lixue Yang; Feng Yang, The First Clinical Medical College, Shaanxi University of Chinese Medicine, Vice No. 2, West Weiyang Road, Qindu District, Shaanxi, 712000, People’s Republic of China, Email ylx18391076233@163.com; yangfengdudu@163.comBackground and Purpose: Lumbar disc herniation (LDH) significantly impacts individuals, particularly those aged 40– 45. …”
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Manipulated Slow Release of Florfenicol Hydrogels for Effective Treatment of Anti-Intestinal Bacterial Infections
Published 2025-01-01“…Wanhe Luo,1,2 Mengdi Zhang,1 Yongtao Jiang,1 Guocai Ma,3 Jinhuan Liu,1,4 Ali Sobhy Dawood,5 Shuyu Xie,6 Samah Attia Algharib7 1College of Animal Science and Technology, Tarim University, Alar, Xinjiang, 843300, People’s Republic of China; 2Key Laboratory of Livestock and Forage Resources Utilization Around Tarim, Ministry of Agriculture and Rural Areas, Tarim University, Alar, Xinjiang, 843300, People’s Republic of China; 3Instrumental Analysis Center, Tarim University, Alar, Xinjiang, 843300, People’s Republic of China; 4Lab for Sustainable Antimicrobials, Department of Pharmacy, Sichuan Agricultural University, Chengdu, Sichuan, 610000, People’s Republic of China; 5Medicine and Infectious Diseases Department, Faculty of Veterinary Medicine, University of Sadat City, Sadat city, 32897, Egypt; 6National Reference Laboratory of Veterinary Drug Residues (HZAU) and MARA Key Laboratory for Detection of Veterinary Drug Residues, Huazhong Agricultural University, Wuhan, Hubei, 430070, People’s Republic of China; 7Department of Clinical Pathology, Faculty of Veterinary Medicine, Benha University, Moshtohor, Toukh, 13736, EgyptCorrespondence: Wanhe Luo; Samah Attia Algharib, Email luowanhe0728@163.com; samah.alghareeb@fvtm.bu.edu.egObjective: The difficulty of establishing slow release at intestinal infection sites, weak antibacterial effects, as well as the limited broad use of florfenicol oral formulations are the main targets of the current study. …”
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Early weight gain after stopping smoking: a predictor of overall large weight gain? A single-site retrospective cohort study
Published 2018-12-01“…We examined whether early large postcessation weight gain predicts overall large weight gain.Design Retrospective cohort study.Setting Primary care setting—smoking cessation centre in Prague, Czech Republic.Participants Out of 3537 patients treated between 2005 and 2013, 1050 were continuous abstainers (verified by carbon monoxide measurement) at 1-year follow-up and formed the cohort of the current report. 48.7% were women (n=511) with the mean age of 46 (±14.4) years.Methods In this retrospective cohort study, all patients underwent usual tobacco dependence treatment using evidence-based methods. …”
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