INTEGRATION OF A DATA-DRIVEN SOFTWARE APPLICATION AND A MULTIMODAL LARGE LANGUAGE MODEL FOR ENHANCED NUTRITIONAL GUIDANCE: A CASE STUDY by IAPĂSCURTĂ, Victor, ȚURCANU, Dinu, SIMINIUC, Rodica

Get full text

Salicylanilide Diethyl Phosphates as Potential Inhibitors of Some Mycobacterial Enzymes by Martin Krátký, Eva Novotná, Shalini Saxena, Perumal Yogeeswari, Dharmarajan Sriram, Markéta Švarcová, Jarmila Vinšová

Get full text

Constraining the Gamma-Ray Burst Jet Opening Angle Based on the Very Steep Decay Phase by Qian Xu, Dong-Jie Liu, Yuan-Chuan Zou

Get full text

PARE: Profile-Applied Reasoning Engine for Context-Aware System by M. Robiul Hoque, M. Humayun Kabir, Hyungyu Seo, Sung-Hyun Yang

Get full text

MAMMOTH-Subaru. II. Diverse Populations of Circumgalactic Lyα Nebulae at Cosmic Noon by Mingyu Li, Haibin Zhang, Zheng Cai, Yongming Liang, Nobunari Kashikawa, Ke Ma, Xiaohui Fan, J. Xavier Prochaska, Bjorn H. C. Emonts, Xin Wang, Yunjing Wu, Shiwu Zhang, Qiong Li, Sean D. Johnson, Minghao Yue, Fabrizio Arrigoni Battaia, Sebastiano Cantalupo, Joseph F. Hennawi, Satoshi Kikuta, Yuanhang Ning, Masami Ouchi, Rhythm Shimakawa, Ben Wang, Weichen Wang, Zheng Zheng, Zhen-Ya Zheng

Get full text

A Decade of GRB Follow-Up by BOOTES in Spain (2003–2013) by Martin Jelínek, Alberto J. Castro-Tirado, Ronan Cunniffe, Javier Gorosabel, Stanislav Vítek, Petr Kubánek, Antonio de Ugarte Postigo, Sergey Guziy, Juan C. Tello, Petr Páta, Rubén Sánchez-Ramírez, Samantha Oates, Soomin Jeong, Jan Štrobl, Sebastián Castillo-Carrión, Tomás Mateo Sanguino, Ovidio Rabaza, Dolores Pérez-Ramírez, Rafael Fernández-Muñoz, Benito A. de la Morena Carretero, René Hudec, Víctor Reglero, Lola Sabau-Graziati

Get full text

Improving tropical cyclone rapid intensification forecasts with satellite measurements of sea surface salinity and calibrated machine learning by Ryan Eusebi, Hui Su, Longtao Wu, Pingping Rong, Karthik Balaguru, Ruby Leung, Yong-Sang Choi, Pak Wai Chan, Jianping Gan, Mark DeMaria, Galina Chirokova

Get full text

A Nomogram Based on Laboratory Data, Inflammatory Bowel Disease Questionnaire and CT Enterography for Activity Evaluation in Crohn’s Disease by Zhang H, Shen Y, Cao B, Zheng X, Zhao D, Hu J, Wu X

“…Han Zhang,1,* Yi Shen,1,* Bo Cao,2 Xiaomin Zheng,1 Dehan Zhao,3 Jing Hu,4 Xingwang Wu1 1Department of Radiology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, 230022, People’s Republic of China; 2Department of Radiology, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, 210011, People’s Republic of China; 3Department of Precision Machinery and Precision Instrumentation, University of Science and Technology of China, Hefei, Anhui, 230022, People’s Republic of China; 4Department of Gastroenterology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, 230022, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jing Hu, The First Affiliated Hospital of Anhui Medical University, Department of Gastroenterology, Hefei, Anhui, 230022, People’s Republic of China, Tel +86 139-5510-7753, Email hujing810@163.com Xingwang Wu, The First Affiliated Hospital of Anhui Medical University, Department of Radiology, Hefei, Anhui, 230022, People’s Republic of China, Tel +86 153-7533-0696, Email duobi2004@126.comBackground: Accurately assessing the activity of Crohn’s disease (CD) is crucial for determining prognosis and guiding treatment strategies for CD patients.Objective: This study aimed to develop and validate a nomogram for assessing CD activity.Methods: The semi-automatic segmentation method and PyRadiomics software were employed to segment and extract radiomics features from the spectral CT enterography images of lesions in 107 CD patients. …”
Get full text

The Impact of Online Interactive Platform Services on Oral Health Behaviors in Older Adults With Mild Cognitive Impairment: Protocol for a Randomized Controlled Trial by Yin Q, Chai Z, Tao B, Liu P, Luo Y, Zhao Q, Yang B

“…Qianyu Yin,1,2,* Zhaowu Chai,3,* Binbin Tao,1,2 Ping Liu,1,2 Yu Luo,1,2 Qinghua Zhao,4 Bing Yang1 1Department of Nursing, the Affiliated Stomatological Hospital of Chongqing Medical University, Chongqing, People’s Republic of China; 2College of Nursing, Chongqing Medical University, Chongqing, People’s Republic of China; 3Outpatient Department at Longfor Guangnian, the Affiliated Stomatological Hospital of Chongqing Medical University, Chongqing, People’s Republic of China; 4Center of Nursing Research, the First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Qinghua Zhao, Center of Nursing Research, the First Affiliated Hospital of Chongqing Medical University, Yuzhong District, Chongqing, 400016, People’s Republic of China, Tel +86 18602308866, Email 201307@hospital.cqmu.edu.cn Bing Yang, Department of Nursing, the Affiliated Stomatological Hospital of Chongqing Medical University, Yubei District, Chongqing, 401147, People’s Republic of China, Tel +86 13228649430, Email yangb@hospital.cqmu.edu.cnPurpose: Older adults with mild cognitive impairment (MCI) are at a high risk for oral health decline. …”
Get full text

Novel Nanozyme-Based Multicomponent in situ Hydrogels with Antibacterial, Hypoxia-Relieving and Proliferative Properties for Promoting Gastrostomy Tube Tract Maturation by Xiao F, Yan B, Yuan T, He Y, Zhang X, He X, Peng W, Xu Y, Cao J

“…Feng Xiao,1,* Bisong Yan,2,* Tianwen Yuan,2 Yang He,2 Xiaojun Zhang,3 Xiaoyun He,1 Wei Peng,1 Ying Xu,3 Jun Cao1,4 1Shanghai Eighth People’s Hospital, Xuhui District, Shanghai, 200030, People’s Republic of China; 2Department of Interventional Oncology, Dahua Hospital, Xuhui District, Shanghai, 200237, People’s Republic of China; 3College of Pharmacy, Jiangsu University, Zhenjiang, 212013, People’s Republic of China; 4Shanghai University of Medicine and Health Science, Pudong New Area, Shanghai, 201318, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jun Cao, Shanghai Eighth People’s Hospital, Xuhui District, Shanghai, 200030, People’s Republic of China, Email juncao11@sina.com Ying Xu, College of Pharmacy, Jiangsu University, Zhenjiang, 212013, People’s Republic of China, Email ingyx@sina.com.cnPurpose: Gastrostomy is the commonly used enteral feeding technology. …”
Get full text

Association of Serum Irisin With Severity and Prognosis in Patients With Coronavirus Disease 2019: A Prospective Cohort Study by Zhang X, Wang W, Li Y, Liu X, Zhang L, Cheng Z, Liu M, Wang Y, Fu L, Yang J

“…Xinli Zhang,1,2,* Wennan Wang,1,3,* Ye Li,2 Xiaoning Liu,2 Liangzhu Zhang,2 Zhenyu Cheng,1,4 Mingyan Liu,1,4 Yu Wang,1,4 Lin Fu,1,4 Jin Yang1,4,5 1Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province, People’s Republic of China; 2The First Department of Tuberculosis, Anhui Chest Hospital, Hefei, Anhui Province, People’s Republic of China; 3The Fifth Department of Tuberculosis, Anhui Chest Hospital, Hefei, Anhui Province, People’s Republic of China; 4Institute of Respiratory Diseases, The Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province, People’s Republic of China; 5Information Management Center, The Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province, People’s Republic of China*These authors contributed equally to this workCorrespondence: Lin Fu; Jin Yang, Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province, People’s Republic of China, Email fulindev@126.com; yangqj1015@foxmail.comBackground: Irisin is the cleaved form of fibronectin type III domain-containing protein 5 (FNDC5), which can confer antioxidant and anti-inflammatory effects. …”
Get full text

Clinical Usefulness of Bioavailable Vitamin D and Impact of GC Genotyping on the Determination of Bioavailable Vitamin D in a Korean Population by Hyun-Young Kim, Jin Hyun Kim, Myeong Hee Jung, In Ae Cho, Youngjin Kim, Min-Chul Cho

Get full text

Protective Effect of Rosmarinic Acid on Endotoxin-Induced Neuronal Damage Through Modulating GRP78/PERK/MANF Pathway by Li Q, Zheng JW, Wang ZY, Liao SP, Zhu L, Wang X, Wan LH

“…Qian Li,1,* Jing-Wen Zheng,1,* Zi-Yao Wang,1 Shi-Ping Liao,2 Ling Zhu,1 Xia Wang,3,* Li-Hong Wan1,4,* 1Department of Pharmacology, West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu, Sichuan, 610041, People’s Republic of China; 2Functional Laboratory, West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu, Sichuan, 610041, People’s Republic of China; 3Department of Laboratory Medicine, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, 610041, People’s Republic of China; 4NHC Key Laboratory of Chronobiology (Sichuan University), West China School of Basic Medical Sciences & Forensic Medicine, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, 610041, People’s Republic of China*These authors contributed equally to this workCorrespondence: Li-Hong Wan, Department of Pharmacology, West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu, 3-17 Renmin South Road, Sichuan, 610041, People’s Republic of China, Tel +86-28-85501278, Email wanlihong1976@sina.com Xia Wang, Department of Laboratory Medicine, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, 610041, People’s Republic of China, Email 80832491@qq.comObjective: Neuronal damage is criminal to cognitive dysfunction, closely related to endoplasmic reticulum stress (ERS). …”
Get full text

Factors associated with cervical cancer screening among women of reproductive age in Moshi municipality, Kilimanjaro, Tanzania: a cross-sectional study by Sia E Msuya, Jeremiah John Hhera, Regina Dahaye, Witness Erasto Zakayo, Yohana Z Kazula, Seif Abdul, Redempta Mamseri

Get full text

Identification and Characterization of Genes Associated with Intestinal Ischemia-Reperfusion Injury and Oxidative Stress: A Bioinformatics and Experimental Approach Integrating Hig... by Xie Y, Yang M, Huang J, Jiang Z

“…Yongguo Xie,1,* Mingpu Yang,2,* Juanjuan Huang,3 Zongbin Jiang4 1Department of Anesthesiology, The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region, 530007, People’s Republic of China; 2General Surgery, The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region, 530007, People’s Republic of China; 3Department of Microbiology, School of Basic Medical Sciences, Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region, 530021, People’s Republic of China; 4Department of Pain Medicine, The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region, 530007, People’s Republic of China*These authors contributed equally to this workCorrespondence: Juanjuan Huang, Department of Microbiology, School of Basic Medical Sciences, Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region, 530021, People’s Republic of China, Email hjjcbw@163.com Zongbin Jiang, Department of Pain Medicine, The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region, 530007, People’s Republic of China, Email jiangzongbin@sr.gxmu.edu.cnPurpose: Intestinal ischemia-reperfusion injury (IIRI) occurs as a result of temporary blood flow interruption, leading to tissue damage upon reperfusion. …”
Get full text

Comprehensive Cervical Cancer Prevention in Tanzania (CONCEPT) study: Cohort profile by Ditte Søndergaard Linde, Vibeke Rasch, Julius D Mwaiselage, Rachel Manongi, Patricia Swai, Chunsen Wu, Bariki Mchome, Johnson Katanga, Crispin Kahesa, Susanne Kjaer

Get full text

Impact of Timing the Combination of Radiotherapy and PD-1 Inhibitors on Outcomes in Patients with Hepatocellular Carcinoma by Zhong L, Peng W, Sun J, Luo Y, Sheng H, Wu Y, Zhou T, Zhou C, Cao C

“…Liting Zhong,1,2,* Weiwei Peng,1,2,* Jingyuan Sun,3 Yongyi Luo,3 Hailong Sheng,4 Yi Wu,5 Tonggang Zhou,5 Chaoming Zhou,1,2 Chuanhui Cao1,3 1Department of Oncology, Ganzhou Hospital-Nanfang Hospital, Southern Medical University, Ganzhou, Jiangxi, People’s Republic of China; 2Department of Oncology, Ganzhou People’s Hospital, Ganzhou, Jiangxi, People’s Republic of China; 3Department of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, People’s Republic of China; 4Department of Radiation Oncology, Zhejiang Provincial People’s Hospital, People’s Hospital of Hangzhou Medical College, Hangzhou, Zhejiang, People’s Republic of China; 5Department of Interventional Radiology, Ganzhou People’s Hospital, Ganzhou, Jiangxi, People’s Republic of China*These authors contributed equally to this workCorrespondence: Chuanhui Cao, Department of Oncology, Ganzhou Hospital-Nanfang Hospital, Southern Medical University, No. 16 Meiguan Avenue, Ganzhou, Jiangxi, People’s Republic of China, Email huichuancao@163.comPurpose: The optimal timing for combining radiotherapy with immunotherapy in patients with hepatocellular carcinoma (HCC) remains uncertain and affects treatment efficacy and patient outcomes. …”
Get full text

A Case Study Identified a New Mutation in the TTN Gene for Inherited Hypertrophic Cardiomyopathy by Dong J, Liu M, Chen Q, Zha L

“…Jiangtao Dong,1– 4,* Meilin Liu,1– 3,* Qianwen Chen,1– 3,5 Lingfeng Zha1– 3 1Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People’s Republic of China; 2Hubei Key Laboratory of Biological Targeted Therapy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People’s Republic of China; 3Hubei Provincial Engineering Research Center of Immunological Diagnosis and Therapy for Cardiovascular Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People’s Republic of China; 4Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People’s Republic of China; 5Department of Pediatric Cardiology, Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430070, People’s Republic of China*These authors contributed equally to this workCorrespondence: Lingfeng Zha, Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Wuhan, 430022, People’s Republic of China, Tel +86-15827177185, Email zhalf@hust.edu.cnBackground: Hypertrophic cardiomyopathy (HCM) is the most common hereditary cardiomyopathy, with variable pathogenesis, clinical presentation, and prognosis. …”
Get full text

The Association of Inflammatory Indexes Derived from Peripheral Blood Cell Count and Clinical Signs with Response to Treatment with Dupilumab in Pediatric Patients with Moderate-to... by Zhang L, Pi J, Wang J, Chen J, Zhang Y, Li J, Wang L, Li Y, Chen A, Luo X, Wang H

“…Lingzhao Zhang,1,2 Jiangshan Pi,1,2 Jinsong Wang,3 Jingsi Chen,1 Yunxuan Zhang,1,2 Jie Li,4 Lingling Wang,1,2 Yue Li,1,2 Anwei Chen,1 Xiaoyan Luo,1,5,* Hua Wang1,2,5,* 1Department of Dermatology, Children’s Hospital of Chongqing Medical University, Chongqing, People’s Republic of China; 2Chongqing Key Laboratory of Child Infection and Immunity, Children’s Hospital of Chongqing Medical University, Chongqing, People’s Republic of China; 3Department of Gastroenterology, Chongqing Dongnan Hospital, Chongqing, People’s Republic of China; 4Department of Pediatrics, Chongqing Jiangjin District Maternal and Child Health Hospital, Chongqing, People’s Republic of China; 5Ministry of Education Key Laboratory of Child Development and Disorders, Children’s Hospital of Chongqing Medical University, Chongqing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hua Wang; Xiaoyan Luo, Department of Dermatology, Children’s Hospital of Chongqing Medical University, No. 136 Zhongshan Second Road, Yuzhong District, Chongqing, 400015, People’s Republic of China, Tel +8615123380348, Email huawang@hospital.cqmu.edu.cn; xyluo@hospital.cqmu.edu.cnBackground: Dupilumab is a safe and effective treatment for moderate to severe atopic dermatitis (AD), but real-world data in pediatric patients in China are limited. …”
Get full text

Early-time Millimeter Observations of the Nearby Type II SN 2024ggi by Maokai Hu, Yiping Ao, Yi Yang, Lei Hu, Fulin Li, Lifan Wang, Xiaofeng Wang

Get full text