Assessment of the Image Quality of Virtual Non-Contrast Dual-energy CT Liver Scans Using Both PSNR and SSIM Methods by Yaguang LI, Jie LI, Tingyu XUE, Jiankui MU, Qiang WANG, Lidong ZHENG, Yong WANG, Licun LEI

“…Conclusion: The VNC DECT image of the liver is of good quality and can accurately reproduce the TNC image, meeting clinical diagnostic needs.…”
Get full text

Development and comprehensive greenness assessment of HPLC method for quality control of β-sitosterol in pharmaceutical ointments with trio-color coded evaluation by Haya I. Aljohar, Abdullah M. Al-Hossaini, Seham A. Alzammay, Samiah Alhabardi, Hadir M. Maher, Aya R. Ahmed

“…Abstract A simple, rapid, and reproducible high-performance liquid chromatography (HPLC) method has been developed and validated for the determination of β-sitosterol in the pharmaceutical dosage form of moist exposed burn ointment (MEBO). …”
Get full text

Commodity risk assessment of debarked conifer wood chips fumigated with sulfuryl fluoride from the US by EFSA Panel on Plant Health (PLH), Antonio Vicent Civera, Paula Baptista, Anna Berlin, Elisavet Chatzivassiliou, Jaime Cubero, Nik Cunniffe, Eduardo de la Peña, Nicolas Desneux, Francesco Di Serio, Anna Filipiak, Beata Hasiow‐Jaroszewska, Hervé Jactel, Blanca Landa, Lara Maistrello, David Makowski, Panagiotis Milonas, Nikos T. Papadopoulos, Roel Potting, Hanna Susi, Dirk Jan Van Der Gaag, Andrea Battisti, Claude Bragard, Christer Magnusson, Hugo Mas, Daniel Rigling, Massimo Faccoli, Alžběta Mikulová, Fabio Stergulc, Eugen Christoph, Olaf Mosbach‐Schulz, Franz Streissl, Paolo Gonthier

“…In particular, it is important to note that SF treatments are generally less effective in eliminating fungi than insects, the required parameters of the fumigation should be met at all points of the pile of wood chips and the time of storage of wood chips before treatment should be kept as short as possible because B. xylophilus can easily reproduce and spread throughout the pile under conducive conditions.…”
Get full text

Automatic Detection of the Aortic Annular Plane and Coronary Ostia from Multidetector Computed Tomography by Patricio Astudillo, Peter Mortier, Johan Bosmans, Ole De Backer, Peter de Jaegere, Francesco Iannaccone, Matthieu De Beule, Joni Dambre

“…The proposed method is accurate, fast, and reproducible. Embedding this tool based on deep learning in the preoperative planning routine may have an impact in the TAVI environments by reducing the time and cost and improving accuracy.…”
Get full text

Is Weight Loss the Main Driver for A1C Improvement by Glucagon‐Like Peptide 1 (GLP‐1) Receptor Agonists? A 2.5‐Year Analysis in Real‐World Clinical Practice by Marwa Al‐Badri, Shilton Dhaver, Osama Hamdy

“…The same observations were reproducible in each medication group. Conclusions These findings suggest that the long‐term improvement in glycemic control associated with GLP‐1 RA therapy is primarily driven by weight loss rather than any other intrinsic effect of GLP‐1 RA. …”
Get full text

Laser-based 3D printing and optical characterization of optical micro-nanostructures inspired by nocturnal insects compound eyes by Bogdan Stefanita Calin, Roxana Cristina Popescu, Eugenia Tanasa, Irina Alexandra Paun

“…Optimized computer-aided design and laser writing parameters enabled us to reproduce the entire complex architecture of moth compound eyes, with submicrometric spatial accuracy. …”
Get full text

Studying Alzheimer’s disease through an integrative serum metabolomic and lipoproteomic approach by Alessia Vignoli, Giovanni Bellomo, Federico Paolini Paoletti, Claudio Luchinat, Leonardo Tenori, Lucilla Parnetti

“…These results were reproduced in the validation set (accuracy 75.0%). Evolution of MCI-AD patients was evaluated over time. …”
Get full text

Biological characteristics of bream (Abramis brama Linnaeus, 1758) of the Kremenchuk Reservoir as an object of commercial fishery by N. Rudyk-Leuska, O. Buzevych, M. Leuskyi, I. Burjak

“…It is caused by the need to obtain up-to-date data on the state of self-reproducing populations with the determination and analysis of integral characteristics that affect the conditions of formation and exploitation of their commercial stock. …”
Get full text

Role of Subsurface Geo-Energy Pilot and Demonstration Sites in Delivering Net Zero by M. H. Stephenson, D. A. C. Manning, M. J. Spence, L. Stalker, Z. K. Shipton, A. A. Monaghan

“…Subsurface net zero technologies have been studied by geologists at laboratory scale and with models, but also require testing at greater-than laboratory scale and in representative conditions not reproducible in laboratories and models. Test, pilot and demonstration facilities aid rock characterisation process understanding and up-scaling, and thereby provide a bridge between laboratory testing and computer modelling and full-scale operation. …”
Get full text

Impact of growing conditions on the gum properties of different genotypes of guar (Cyamopsis tetragonoloba (L.) Taub.) by I. V. Kruchina-Bogdanov, E. V. Miroshnichenko, R. A. Shaukharov, E. N. Kantemirova, M. A. Golovina, K. M. Abdullaev, A. V. Balashov, E. V. Rusinova, P. G. Rusinov, E. K. Potokina

“…As a result, the maximum viscosity values were obtained for the seeds reproduced at the Astrakhan region, where the guar was grown on irrigated lands. …”
Get full text

Different Responses to Drug Safety Screening Targets between Human Neonatal and Infantile Heart Tissue and Cardiac Bodies Derived from Human-Induced Pluripotent Stem Cells by Jan Trieschmann, Moritz Haustein, Annette Köster, Jürgen Hescheler, Konrad Brockmeier, Gerardus Bennink, Tobias Hannes

“…Conclusion. hiPS-CBs were able to reproduce AP prolongation after Ik,r blockade, but to a lesser extent compared to human neonatal and infantile myocardial tissue slices. …”
Get full text

Variación de la saturación de oxígeno en la detección de hipertensión pulmonar by Alirio Bastidas Goyes, Barbarita Mantilla Cardozo, Gustavo Adolfo Hincapié Díaz, Eduardo Tuta Quintero, Juan Sebastián Mancera, Andrés Fernando Pereira, Tatiana Vargas, Abraham José Brito Rodríguez, Stefania Forero Caldas, Cristian Camilo López, Daniel Mateo Prieto, José Ignacio Nuñez

“…Introducción: El análisis de la saturación de oxígeno durante la caminata de 6 minutos, puede representar una herramienta útil, accesible y reproducible en la valoración de los pacientes con hipertensión arterial pulmonar. …”
Get full text

SPIRIT-DEFINE explanation and elaboration: recommendations for enhancing quality and impact of early phase dose-finding clinical trials protocolsResearch in context by Moreno Ursino, Guillermo Villacampa, Jan Rekowski, Munyaradzi Dimairo, Olga Solovyeva, Deborah Ashby, Jordan Berlin, Oliver Boix, Melanie Calvert, An-Wen Chan, Courtney H. Coschi, Thomas R. Jeffry Evans, Elizabeth Garrett-Mayer, Robert M. Golub, Christina Guo, Kathryn S. Hayward, Sally Hopewell, John D. Isaacs, S. Percy Ivy, Thomas Jaki, Olga Kholmanskikh, Andrew Kightley, Shing Lee, Rong Liu, Adrian Mander, Lynley V. Marshall, James Matcham, Dhrusti Patel, Richard Peck, Khadija Rerhou Rantell, Dawn P. Richards, Mahtab Rouhifard, Lesley Seymour, Yoshiya Tanaka, Christopher J. Weir, Johann de Bono, Christina Yap

“…We recommend utilising this paper alongside the SPIRIT statement, and any relevant extensions, to enhance the development and review of EPDF trial protocols.By facilitating adoption of the SPIRIT-DEFINE statement for EPDF trials, this E&E document can promote enhancement of methodological rigour, patient safety, transparency, and facilitate the generation of high-quality, reproducible evidence that will strengthen the foundation of early phase research and ultimately improve patient outcomes. …”
Get full text

Mapping neutron biological effectiveness for DNA damage induction as a function of incident energy and depth in a human sized phantom by Alice Mentana, Virgilio Quaresima, Pavel Kundrát, Isabella Guardamagna, Leonardo Lonati, Ombretta Iaria, Andrea Previtali, Giorgia Santi Amantini, Luca Lunati, Virginia Boretti, Livio Narici, Luca Di Fino, Luca Bocchini, Claudio Cipriani, Giorgio Baiocco

“…Within a coherent modelling framework, this approach tackles the variation of neutron RBE in a wide energy range, from thermal neutrons to neutrons of hundreds of GeV, and reproduces effects related to depth in the human-sized receptor, as well as to the receptor size itself. …”
Get full text

Reproductive modes in populations of late-acting self-incompatible and self-compatible polyploid Ludwigia grandiflora subsp. hexapetala in western Europe by Stoeckel, Solenn, Becheler, Ronan, Portillo-Lemus, Luis, Harang, Marilyne, Besnard, Anne-Laure, Lassalle, Gilles, Causse-Védrines, Romain, Michon-Coudouel, Sophie, Park, Daniel J., Pope, Bernard J., Petit, Eric J., Barloy, Dominique

“…We found that populations reproduced mainly clonally but with a high diversity of genotypes along with rates of sexuality ranging from 10% up to 40%. …”
Get full text

Unveiling the Cosmic Chemistry: Revisiting the Mass–Metallicity Relation with JWST/NIRSpec at 4 < z < 10 by Arnab Sarkar, Priyanka Chakraborty, Mark Vogelsberger, Michael McDonald, Paul Torrey, Alex M. Garcia, Gourav Khullar, Gary J. Ferland, William Forman, Scott Wolk, Benjamin Schneider, Mark Bautz, Eric Miller, Catherine Grant, John ZuHone

“…We introduce an empirical mass–metallicity–redshift relation: $12+{\rm{log}}({\rm{O}}/{\rm{H}})=6.29+0.237$ × $\mathrm{log}({M}_{* }/{M}_{\odot })-0.06\times (1+z)$ , which accurately reproduces the observed trends in metallicity with both redshift and stellar mass. …”
Get full text

Liquid crystal template-assisted electrodeposition of nanoporous nickel microspheres: A sensitive electrochemical sensing platform for electrocatalytic oxidation and quantitative d... by R. Dehdari Vais, M. Negahdary, S.R. Rasouli Nasrabadi, A. Rahi, S.A. Dastgheib, H. Heli

“…The designed sensing platform depicted a stable and reproducible response and insignificant interference from the common species found in the biological fluids and pharmaceutical formulations. …”
Get full text

Administration of Vitamin D Metabolites Affects RNA Expression of Xenobiotic Metabolising Enzymes and Function of ABC Transporters in Rats by Karoline Klumpp, Frauke Lange, Alexandra S. Muscher-Banse, Nadine Schnepel, Kathrin Hansen, Adrian L. Lifschitz, Laura Mate, Mirja R. Wilkens

“…Taken together, the stimulating effects of vitamin D metabolites on the expression of genes involved in the metabolism and elimination of xenobiotics reported previously for rodents and sheep could not be reproduced. In contrast, we even observed a negative impact on the expression of CYP3A enzymes and their most important regulator, the pregnane X receptor. …”
Get full text

Magnetic resonance spectroscopy of hippocampal and striatal neurometabolites in experimental PTSD rat modeling by V. E. Tseilikman, O. B. Shevelev, N. V. Khotskin, A. S. Dotsenko, G. V. Kontsevaya, M. S. Lapshin, M. P. Moshkin, M. V. Komelkova, I. V. Feklicheva, O. B. Tseilikman, E. Dremencov, E. L. Zavjalov

“…The spectrum of the metabolites in the dorsal region of the hippocampus and striatum was studied using the method of 1H magnetic resonance spectroscopy at experimental modeling of the posttraumatic stress disorder syndrome (PTSD) in rats. PTSD was reproduced by exposure of the cat cue to rats daily along 10 day by 10 minutes at once. …”
Get full text

Gaps in our understanding of ice-nucleating particle sources exposed by global simulation of the UK Earth System Model by R. J. Herbert, A. Sanchez-Marroquin, A. Sanchez-Marroquin, D. P. Grosvenor, D. P. Grosvenor, K. J. Pringle, S. R. Arnold, B. J. Murray, K. S. Carslaw

“…We find that the ability of the model to reproduce measured INP concentrations is greatly improved by representing dust as a mixture of mineralogical and organic ice-nucleating components, as present in many soils. …”
Get full text