Membrane-targeted push-pull azobenzenes for the optical modulation of membrane potential by Valentina Sesti, Arianna Magni, Matteo Moschetta, Chiara Florindi, Marlene E. Pfeffer, Mattia Lorenzo DiFrancesco, Michele Guizzardi, Giulia Folpini, Luca Sala, Alessandra Gilda Ritacca, Beatrice Campanelli, Paola Moretti, Giuseppe Maria Paternò, Luca Maragliano, Matteo Tommasini, Francesco Lodola, Elisabetta Colombo, Fabio Benfenati, Chiara Bertarelli, Guglielmo Lanzani

“…Specifically, MTs photoisomerization induces clear and reproducible depolarization. The most promising species, MTP2, was extensively studied. …”
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A simple, highly sensitive and specific serological test for the detection of antibodies to Varicella-zoster virus (<i>Varicellovirus humanalpha3</i>) by Firaya G. Nagieva, Elena P. Barkova, Olga S. Kharchenko, Alexander V. Sidorov, Galina I. Alatortseva, Bogdan S. Cherepovich, Yulia N. Tarakanova, Olga A. Trubacheva, Evgeny A. Pashkov, Artem A. Rtishchev, Oksana A. Svitich, Vitaly V. Zverev

“…A highly specific, sensitive and reproducible tests for the detection of antibodies to VZV have been developed.…”
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Genetic Deletion and Pharmacological Inhibition of PI3Kγ Reduces Neutrophilic Airway Inflammation and Lung Damage in Mice with Cystic Fibrosis-Like Lung Disease by Maria Galluzzo, Elisa Ciraolo, Monica Lucattelli, Eriola Hoxha, Martina Ulrich, Carlo Cosimo Campa, Giuseppe Lungarella, Gerd Doring, Zhe Zhou-Suckow, Marcus Mall, Emilio Hirsch, Virginia De Rose

“…Treatment with the PI3Kγ inhibitor AS-605240 decreased the number of neutrophils in BALF of βENaC-Tg mice, reproducing the effect observed with genetic deletion of the enzyme. …”
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Tree shrew as a new animal model for musculoskeletal disorders and aging by Xiaocui Wei, Honghao Li, Jingyang Qiu, Jianlin Jiao, Xiongtian Guo, Gaosheng Yin, Ping Yang, Yi Han, Qiongzhi Zhao, Hao Zeng, Zhi Rao, Xuefei Gao, Kai Li, Pinglin Lai, Sheng Zhang, Chengliang Yang, Di Lu, Xiaochun Bai

“…The induced OA model in tree shrews was highly efficient and reproducible, characterized by gradual deterioration of articular cartilage, recapitulating the human OA phenotype to some degree. …”
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A microfluidics platform for simultaneous evaluation of sensitivity and side effects of anti-cancer drugs using a three-dimensional culture method by Yuki Kobayashi, Honoka Hashizume, Sotaro Takiguchi, Jiajue Ji, Ryuji Kawano, Keiichiro Koiwai, Haru Yamamoto, Mohamed Elbadawy, Tsutomu Omatsu, Amira Abugomaa, Masahiro Kaneda, Tatsuya Usui, Kazuaki Sasaki

“…These techniques have recently been used to reproduce the structure and function of organs in vitro and are expected to be promising alternatives for animal experiments in the future. …”
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Two-step-7-Pink Rule: A Practical Tool for the Dermoscopic Evaluation of Fully Amelanotic Skin Lesions by Riccardo Pampena, Stefano Migliorati, Giovanni Paolino, Michela Lai, Nicola Lippolis, Stefania Guida, Stefania Borsari, Sebastiano Pellerone, Sofia Maria Di Ciaccio, Elvira Moscarella, Giovanni Pellacani, Giuseppe Argenziano, Caterina Longo

“…Conclusions: The present study showed that an algorithm focused on a few reproducible and easily recognizable criteria could improve diagnostic accuracy in the management of amelanotic lesions. …”
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Liquid Chromatography-Tandem Mass Spectrometry Method for the Determination of Vardenafil and Its Application of Bioequivalence by Kok Zheng Gan, Riyanto Teguh Widodo, Zamri Chik, Lay Kek Teh, Mohd Salleh Rofiee, Mohd Izwan Mohamad Yusof

“…The limit of detection was 0.2 ng/mL. The assay was reproducible with intra-assay and interassay precision ranging 1.17%–9.17% and 1.31%–5.86%, respectively. …”
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Research progress of gut flora in improving human wellness by Chenggang Zhang, Wenjing Gong, Zhihui Li, Dawen Gao, Yan Gao

“…Keywords: Hunger sensation comes from gut flora, Gut flora-centric theory, Flexible fasting, Gut flora priority principle, Universal reproducing power of the microbiota, Gut flora wellness, Human wellness…”
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Prediction of Fracture Evolution and Groundwater Inrush from Karst Collapse Pillars in Coal Seam Floors: A Micromechanics-Based Stress-Seepage-Damage Coupled Modeling Approach by Yinlong Lu, Bingzhen Wu, Mengqi He, Lianguo Wang, Dan Ma, Zhen Huang

“…An in situ high-precision microseismic monitoring technology is used to verify the micromechanical modeling results, which indicate that the numerical model successfully reproduces the damage and fracture evolution in a coal seam floor with a KCP during the mining process. …”
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slendr: a framework for spatio-temporal population genomic simulations on geographic landscapes by Petr, Martin, Haller, Benjamin C., Ralph, Peter L., Racimo, Fernando

“…Together with its R-idiomatic interface to the tskit library for tree-sequence processing and analysis, slendr opens up the possibility of performing efficient, reproducible simulations of spatio-temporal genomic data entirely within the R environment, leveraging its wealth of libraries for geospatial data analysis, statistics, and visualization. …”
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Recommendations for developing, documenting, and distributing data products derived from NEON data by Jeff W. Atkins, Kelly S. Aho, Xuan Chen, Andrew J. Elmore, Rich Fiorella, Wenqi Luo, Danica Lombardozzi, Claire Lunch, Leah Manak, Luis X. dePablo, Allison N. Myers‐Pigg, Sydne Record, Tong Qiu, Samuel Reed, Benjamin Ruddell, Brandon Strange, Christa L. Torrens, Kelsey Yule, Andrew D. Richardson

“…Derived data products are curated, documented, reproducibly‐generated datasets created by applying various processing steps to one or more lower level data products—including interpolation, extrapolation, integration, statistical analysis, modeling, or transformations. …”
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ATClean: A Novel Method for Detecting Low-luminosity Transients and Application to Pre-explosion Counterparts from SN 2023ixf by S. Rest, A. Rest, C. D. Kilpatrick, J. E. Jencson, S. von Coelln, L. Strolger, S. Smartt, J. P. Anderson, A. Clocchiatti, D. A. Coulter, L. Denneau, S. Gomez, A. Heinze, R. Ridden-Harper, K. W. Smith, B. Stalder, J. L. Tonry, Q. Wang, Y. Zenati

“…From ATLAS o -band imaging at the site of the Type II supernova (SN) 2023ixf in M101 from 2015–2023, we show that this method accurately reproduces the 3 σ flux limits produced from other, more computationally expensive methods. …”
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Quasi-parallel Antisunward-propagating Whistler Waves Associated with the Electron Deficit in the Near-Sun Solar Wind: Particle-in-cell Simulation by Alfredo Micera, Daniel Verscharen, Jesse T. Coburn, Maria Elena Innocenti

“…By employing particle-in-cell simulations, we study electron VDFs that reproduce those typically observed in the inner heliosphere and investigate whether the electron deficit may contribute to the onset of kinetic instabilities. …”
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Experimental and Modeling Study for the Solar-Driven CO₂ Electrochemical Reduction to CO by Matteo Agliuzza, Roberto Speranza, Andrea Lamberti, Candido Fabrizio Pirri, Adriano Sacco

“…The integrated device successfully produces CO with a faradaic efficiency of 73.85% at a current density of J = 3.35 mA/cm² under 1 sun illumination, with the result validated and reproduced by the mathematical model. Under reduced illumination conditions of 0.8 and 0.6 suns, faradaic efficiencies of 68.5% and 64.1% were achieved, respectively.…”
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Toward enhanced quality assurance guidelines for deep hyperthermia devices: a multi-institution study by Mattia De Lazzari, Carolina Carrapiço-Seabra, Dietmar Marder, Gerard C. van Rhoon, Sergio Curto, Hana Dobšíček Trefná

“…We propose minimum acceptable values for each quality parameter based on these results.Conclusion The measurements were reproducible with acceptable values for the various quality parameters. …”
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NMDA Reduces Tau Phosphorylation in Rat Hippocampal Slices by Targeting NR2A Receptors, GSK3β, and PKC Activities by Audrée De Montigny, Ismaël Elhiri, Julie Allyson, Michel Cyr, Guy Massicotte

“…Our results demonstrated that Tau phosphorylation at Ser199-202 residues was decreased in NMDA-treated hippocampal slices, an effect that was not reproduced at Ser262 and Ser404 epitopes. NMDA-induced reduction of Tau phosphorylation at Ser199-202 was further promoted when NR2A-containing receptors were pharmacologically isolated and were completely abrogated by the NR2A receptor antagonist NVP-AAM077. …”
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MHD‐Test Particles Simulations of Moderate CME and CIR‐Driven Geomagnetic Storms at Solar Minimum by Mary K. Hudson, Scot R. Elkington, Zhao Li, Maulik Patel, Kevin Pham, Kareem Sorathia, Alex Boyd, Allison Jaynes, Alexis Leali

“…Results were compared directly with measurements and found to reproduce magnetopause loss for the CME‐shock event and increased PSD for the CIR event. …”
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Trade-off strategies between growth and defense of spring ephemeral plants in early spring by Liben Pan, Liben Pan, Tianqi Wang, Tianqi Wang, Vladimir L. Gavrikov, Xiaorui Guo, Xiaorui Guo, Liqiang Mu, Zhonghua Tang, Zhonghua Tang

“…Plants at higher elevations demonstrated higher leaf dry matter content and leaf total flavonoid concentration, and lower nitrogen concentration, influenced by temperature, precipitation, and soil nutrients.DiscussionThese results demonstrated that spring ephemerals have a strong nutrient uptake capacity, and adopt resource competition strategies to rapidly accumulate nutrients and reproduce. The plants at higher elevations adopt more conservative strategies, with trait networks showing increased modularity, edge density, and closer correlations among traits to enhance resource utilization. …”
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Rapid Determination of the Monosaccharide Composition and Contents in Tea Polysaccharides from Yingshuang Green Tea by Pre-Column Derivatization HPLC by Yujie Ai, Zhi Yu, Yuqiong Chen, Xiaojing Zhu, Zeyi Ai, Shuyuan Liu, Dejiang Ni

“…In conclusion, pre-column derivatization HPLC provides a rapid, reproducible, accurate, and quantitative method for analysis of the monosaccharide composition and contents in TPS, which may help to further explore the relationship between TPS monosaccharides isolated from different tea varieties and their biological activity.…”
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Immersive virtual reality to assess unilateral spatial neglect in stroke patients: a preliminary study by Chloé Sauvage, Pierre Chaulet, Luana Rivas Lopez, Johanne Garbusinski, Pierre Cabaraux, Zachary Duvigneaud, Stéphane Baudry

“…In CVR, the Bells Test is reproduced in the same format as PP (A4 sheet), while in EVR, the targets are displayed in a wider space corresponding to a hemisphere of 1-m radius. …”
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