A KSHV RNA-binding protein promotes FOS to inhibit nuclease AEN and transactivate RGS2 for AKT phosphorylation by Vladimir Majerciak, Beatriz Alvarado-Hernandez, Yanping Ma, Shivalee Duduskar, Alexei Lobanov, Maggie Cam, Zhi-Ming Zheng

“…Using an optimized CLIP-seq in this report, we identified ORF57-bound transcripts from 544 host protein-coding genes. …”
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Risk factors for dengue mortality: a 7-year retrospective cohort in Honduras by Dilcia Sauceda-Acosta, Sandra Paola Paz Almendares, Elsy Cárcamo, Melba Zúniga-Gutiérrez, Briana Beltrán, María Félix Rivera, Marlon Meléndez Rodríguez, Judy Enamorado

“…Among surviving patients, the largest age groups were 20–49 years (28.9%) and 10–19 years (28.2%). Francisco Morazán reported the most dengue cases, while Cortés had the highest dengue deaths. …”
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Dual Clinical Practice (DCP) policy to improve the retention of human resources for health in Rwanda: a mid-term review using a cross-sectional and retrospective study design by Kizito Kayumba, Corneille Ntihabose, Sabine Musange Furere, Bernard Ngabo, Piero Irakiza, Felix K. Rubuga, Nathalie Umutoni, Ina Rukundo Kalisa, Pascal Birindabagabo, Emile Rwamasirabo, Emmanuel Kayibanda, Patience Mukundirukuri, Gashaija Absolomon, Sumana Dhanani, Jeanine Condo

“…Providers expressed strong support for the policy, and patient satisfaction was high, with 81% of patients reporting positive experiences with DCP services. The scheme contributed to increased patient enrollment and hospital revenue, particularly in urban facilities. …”
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The hidden crisis: double burden of malnutrition among refugee children in South Asia – a systematic review and meta-analysis from observational studies by Pooja Panchal, Mohd Usman, Tajung Longkumer, Reshma Susan Babu, Mahalaqua Nazil Khatib, Shariza Abdul Razak, Kavitha Menon

“…The study aims to assess the prevalence of malnutrition among refugee children in South Asia.MethodsThis systematic review and meta-analysis followed the standard Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 guidelines using CoCoPop mnemonic approach. …”
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Dose-dependent serological profiling of AdCLD-CoV19-1 vaccine in adults by Jung Hyuk Lee, Yuna Shin, Kwang-Soo Shin, Ju Yeon Park, Mi Sun Kim, Young-Shin Park, Wuhyun Kim, Joon Young Song, Ji Yun Noh, Hee Jin Cheong, Chang-Yuil Kang, Sang Hwan Seo, Jae-Ouk Kim, Deok Ryun Kim, Nathaniel S. Hwang, Jae Seung Yang, Jerome H. Kim, Byoung-Shik Shim, Manki Song

“…ABSTRACT AdCLD-CoV19-1, a chimeric adenovirus-based severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine, was previously reported to elicit robust antibody responses in mice and non-human primates after a single dose. …”
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Comprehensive evaluation of physico-chemical, antioxidant, and antimicrobial properties in commercial soaps: A study on bar soaps and liquid hand wash by Jannatul Ferdous Nova, Susmita Zaman Smrity, Mahadi Hasan, Md. Tariquzzaman, Md Al Amin Hossain, Md. Tanvirul Islam, Md. Raysul Islam, Selina Akter, Md. Sifat Rahi, Md. Tuhinur R. Joy, Zannatul Kowser

“…Moreover, 8 soaps show antimicrobial properties against Staphylococcus aureus, which were further tested for rapid efficacy and antioxidant properties. A survey report of 22 commercial branded soaps was done on 50 people in Bangladesh to get feedback from customers. …”
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A Digital Parenting Intervention With Intimate Partner Violence Prevention Content: Quantitative Pre-Post Pilot Study by Moa Schafer, Jamie Lachman, Paula Zinser, Francisco Antonio Calderón Alfaro, Qing Han, Chiara Facciola, Lily Clements, Frances Gardner, Genevieve Haupt Ronnie, Ross Sheil

“…Descriptive statistics were used to report sociodemographic characteristics and engagement outcomes. …”
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The Relationship between Body Mass Index and Incident Diabetes Mellitus in Chinese Aged Population: A Cohort Study by M. L. Tang, Y. Q. Zhou, A. Q. Song, J. L. Wang, Y. P. Wan, R. Y. Xu

“…Objectives. Previous studies reported that overweight older adults had a lower mortality after cardiovascular diseases attack, indicating being thinner might not always be better. …”
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Ensemble estimates of global wetland methane emissions over 2000–2020 by Z. Zhang, B. Poulter, J. R. Melton, W. J. Riley, G. H. Allen, D. J. Beerling, P. Bousquet, J. G. Canadell, E. Fluet-Chouinard, P. Ciais, N. Gedney, P. O. Hopcroft, A. Ito, R. B. Jackson, A. K. Jain, K. Jensen, F. Joos, T. Kleinen, S. H. Knox, S. H. Knox, T. Li, X. Li, X. Liu, K. McDonald, G. McNicol, P. A. Miller, J. Müller, P. K. Patra, P. K. Patra, C. Peng, S. Peng, Z. Qin, R. M. Riggs, M. Saunois, Q. Sun, H. Tian, X. Xu, Y. Yao, Y. Xi, W. Zhang, W. Zhang, Q. Zhu, Q. Zhu, Q. Zhuang

“…<p>Due to ongoing climate change, methane (CH<span class="inline-formula">₄</span>) emissions from vegetated wetlands are projected to increase during the 21st century, challenging climate mitigation efforts aimed at limiting global warming. However, despite reports of rising emission trends, a comprehensive evaluation and attribution of recent changes remains limited. …”
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Identification of the clinical and genetic characteristics of gliomas with gene fusions by integrated genomic and transcriptomic analysis by Guo-zhong Yi, Hua-yang Zhang, Tian-shi Que, Shan-qiang Qu, Zhi-yong Li, Song-tao Qi, Wen-yan Feng, Guang-long Huang

“…Our study has identified a set of gene fusions present in gliomas, including a number of novel gene fusions that have not been previously reported. We have also elucidated the underlying genetic characteristics of glioma with gene fusions. …”
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OXA β-lactamases from Acinetobacter spp. are membrane bound and secreted into outer membrane vesicles by Lucia Capodimonte, Fernando Teixeira Pinto Meireles, Guillermo Bahr, Robert A. Bonomo, Matteo Dal Peraro, Carolina López, Alejandro J. Vila

“…Their catalytic function (cleaving β-lactam antibiotics) occurs in the bacterial periplasm, where they are commonly reported as soluble proteins. A bioinformatic analysis reveals a significant number of putative lipidated β-lactamases, expected to be attached to the outer bacterial membrane. …”
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Iron deficiency in endure athletes by Michał Rogulski, Yauheniya Patarocha, Aleksandra Ślusarska, Jolanta Mędyk, Paulina Błasiak, Małgorzata Wirkijowska, Patryk Mikołajec, Ruslan Huk, Barbara Bilecka, Jakub Wirkijowski

“…Methods: Our study followed the guidelines of Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) [9]. …”
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Preparation of Nutmeg Gel and Evaluation of its Efficacy as Local Drug Delivery in Stage II Grade A Periodontitis Patients: A Prospective Interventional Study by Vazeeha Afrin Syed, AS Pavithra, Arvina Rajasekar, Rajeshkumar Shanmugam

“…Followed by in-vitro analysis, 40 patients with stage II grade A periodontitis patients who reported between June 2023 and September 2023 to the Department of Periodontology were enrolled. …”
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Trends in certifications of overall vision impairment and that due to diabetic retinopathy/maculopathy in England and Wales, 2009/2010 to 2019/2020: a retrospective database analys... by Catey Bunce, Gwyn Samuel Williams, David Owens, Wen Xing, Rhianon Reynolds, Antra Zekite, Declan Flanagan, RL Thomas, Rebecca John

“…Objectives This study aims to report the trends in the certification of both sight impairment (SI) and severe sight impairment (SSI) in England and Wales during the period of 2010 to 2020, prior to the COVID-19 pandemic. …”
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First-in-human phase I trial of the bispecific CD47 inhibitor and CD40 agonist Fc-fusion protein, SL-172154 in patients with platinum-resistant ovarian cancer by Lini Pandite, Simon Metenou, Debra L Richardson, Erika Hamilton, Linda Van Le, Bo Ma, Fatima Rangwala, Nehal J Lakhani, Justin Call, Daphne Stewart, Lauren E Dockery, Guanfang Wang, Jade Huguet, Elliot Offman

“…Treatment-emergent adverse events (TEAEs) were reported for 27 patients (100%), with 24 (88.9%) having a drug-related TEAE and infusion-related reactions being the most common. 12 patients (44.4%) had grade 3/4 TEAEs, and half of these patients (22.2%) had a drug-related grade 3/4 TEAE. …”
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Borrelia burgdorferi radiosensitivity and Mn antioxidant content: antigenic preservation and pathobiology by Andrés F. Londoño, Ajay Sharma, Jared Sealy, Vipin S. Rana, Shelby D. Foor, Vera Y. Matrosova, Elena K. Gaidamakova, Robert P. Volpe, Michael J. Daly, Brian M. Hoffman, Utpal Pal, J. Stephen Dumler

“…Contrary to expectations, we report that wild-type B. burgdorferi B31 cells are radiosensitive, with a gamma-radiation survival limit for 106 wild-type cells of <1 kGy. …”
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Association between prognosis and the use of angiotensin‐converting enzyme inhibitors and/or angiotensin II receptor blockers in frail patients with heart failure with preserved ej... by Akihiro Sunaga, Shungo Hikoso, Shunsuke Tamaki, Masahiro Seo, Masamichi Yano, Takaharu Hayashi, Akito Nakagawa, Yusuke Nakagawa, Hiroyuki Kurakami, Tomomi Yamada, Tetsuhisa Kitamura, Taiki Sato, Bolrathanak Oeun, Hirota Kida, Yohei Sotomi, Tomoharu Dohi, Katsuki Okada, Hiroya Mizuno, Daisaku Nakatani, Takahisa Yamada, Yoshio Yasumura, Yasushi Sakata, OCVC‐Heart Failure Investigators

“…Abstract Aims The effectiveness of angiotensin‐converting enzyme inhibitors (ACE‐I) and angiotensin II receptor blockers (ARB) has not been demonstrated in patients with heart failure with preserved ejection fraction (HFpEF). We recently reported significant interaction between the use of ACE‐I and/or ARB (ACE‐I/ARB) and frailty on prognosis in patients with HFpEF. …”
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Efficacy and safety of combined Kahook Dual Blade goniotomy with phacoemulsification in Chinese patients with primary open angle glaucoma by Lin Fu, Jiang-Tao Lou, Yue Guo, Pei-Juan Wang, Rong-Rong Le, Shu-Xia Xu, Guo-Xing Li, Yuan-Bo Liang

“…AIM: To report the one-year surgical outcome Kahook Dual Blade goniotomy combined with phacoemulsification (KDB-Phaco) in Chinese patients with primary open angle glaucoma (POAG). …”
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Risk factors and consequences of traumatic brain injury in a Swiss male population cohort by Jean-Bernard Daeppen, Gerhard Gmel, Joseph Studer, Valentin Petre Matei, Alina Elena Rosca, Alexandru Neculai Pavel, Radu Mihai Paun

“…The predictors were previous TBI (lifetime TBI but not in the past 12 months at FU2), SUD, personality traits and sociodemographics (highest level of achieved education, age, linguistic region) measured at FU1.Results At FU2, 3919 (80.3%) participants reported to never have had TBI, 102 (2.1%) have had TBI in the last 12 months (TBI new cases), and 860 (17.6%) have had TBI during their lifetime but not in the 12 months preceding FU2 (previous TBI). …”
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Comparative evaluation of sensititre YeastOne and VITEK2 antifungal susceptibility tests with CLSI broth microdilution method of clinical Cryptococcus isolates in Taiwan by Tzu-Ping Weng, Shin-Wei Wang, Shih-Ting Lo, Shu-Li Su, Ming-I Hsieh, Pei-Jane Tsai, Pei-Fang Tsai, Chi-Jung Wu, Nan-Yao Lee, Wen-Chien Ko, Po-Lin Chen

“…Uncorrelation of antifungal susceptibility patterns by SYO and therapeutic outcomes had been recently reported. We compared the performance of current commercial susceptibility tests with the standard CLSI broth microdilution (BMD) method for clinical Cryptococcus isolates. …”
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