Intra-Arterial Chemotherapy with Doxorubicin and Cisplatin Is Effective for Advanced Hepatocellular Cell Carcinoma by Ming-Chun Ma, Yen-Yang Chen, Shau-Hsuan Li, Yu-Fan Cheng, Chih-Chi Wang, Tai-Jan Chiu, Sung-Nan Pei, Chien-Ting Liu, Tai-Lin Huang, Chen-Hua Huang, Yu-Li Su, Yen-Hao Chen, Sheng-Nan Lu, Kun-Ming Rau

“…This study demonstrated clinical efficacy and tolerable side effects of repeated IACT with doxorubicin and cisplatin in advanced HCC. …”
Get full text

Bridging brain and blood: a prospective view on neuroimaging-exosome correlations in HIV-associated neurocognitive disorders by Haixia Luo, Junzhuo Chen, Jiaojiao Liu, Wei Wang, Chuanke Hou, Xingyuan Jiang, Juming Ma, Fan Xu, Xire Aili, Zhongkai Zhou, Hongjun Li, Hongjun Li, Hongjun Li

“…Neuroimaging, particularly magnetic resonance imaging (MRI), offers a non-invasive and repeatable method to monitor subtle changes in brain structure and function, potentially detecting early signs of HAND. …”
Get full text

Acute Bronchiolitis To Pediatric Inpatient Clinic In Patients Under 2 Years Old, Installed with Diagnosis Investigation of the Relationship of Bronchiolitis and Asthma by Selin Kuzucu, İpek Türktaş, Tuğba Bedir Demirdağ, Meltem Polat, Hasan Tezer, Anıl Tapısız, Nazmi Mutlu Karakaş, Ayşe Tana Aslan, Hakan Tüzün

“…Moreover, 41% of patients with repeated hospitalizations and 64.1% API (+) reinforce this view. …”
Get full text

Exposure to Air Pollution Exacerbates Inflammation in Rats with Preexisting COPD by Jing Wang, Ya Li, Peng Zhao, Yange Tian, Xuefang Liu, Huihui He, Rui Jia, Brian G. Oliver, Jiansheng Li

“…Cardinal features of human COPD were induced in a rat model by repeated cigarette smoke inhalation and bacterial infection for 8 weeks. …”
Get full text

Improving sensory integration in Chinese children with moderate sensory integration challenges through engaging basketball training by Sha Ge, Xuepeng Guo, Bo Y. Jiang, Alberto Cordova, Jianmin Guan, John Q. Zhang, Wan X. Yao

“…Separate 2 (Group) × 2 (Test Phases) Analysis of Variance (ANOVA) with repeated measures on the second factor were conducted for each measure. …”
Get full text

Acute aerobic exercise enhances associative learning in regular exercisers but not in non-regular exercisers by Kayleigh D. Gultig, Cornelis P. Boele, Cornelis P. Boele, Lotte E. M. Roggeveen, Ting Fang Soong, Sebastiaan K. E. Koekkoek, Chris I. De Zeeuw, Chris I. De Zeeuw, Henk-Jan Boele, Henk-Jan Boele, Henk-Jan Boele

“…IntroductionPhysical exercise has repeatedly been reported to have advantageous effects on brain functions, including learning and memory formation. …”
Get full text

Identification and quantification of transposable element transcripts using Long-Read RNA-seq in Drosophila germline tissues by Rebollo, Rita, Gerenton, Pierre, Cumunel, Eric, Mary, Arnaud, Sabot, François, Burlet, Nelly, Gillet, Benjamin, Hughes, Sandrine, S. Oliveira, Daniel, Goubert, Clément, Fablet, Marie, Vieira, Cristina, Lacroix, Vincent

“…Transposable elements (TEs) are repeated DNA sequences potentially able to move throughout the genome. …”
Get full text

Self-perceived middle-distance race pace is faster in advanced footwear technology spikes by Montgomery Bertschy, Victor Rodrigo-Carranza, Ethan W.C. Wilkie, Laura A. Healey, Jeremy Noble, Wayne J. Albert, Wouter Hoogkamer

“…., “spikes”) in middle-distance events is challenging, because repeated maximal effort trials (as in sprinting) or aerobic running economy trials (as in long-distance running) are not feasible. …”
Get full text

Multi-disciplinary treatment of broncho-esophageal fistula in a high-risk single-lung patient by Rune Haaverstad, Kjell Ovrebo, Lorentz Sandvik, Håvard Seland, Gunnar Reksten Husebø, Vegard Skalstad Ellensen, Marit Farstad, Eivind Strandenes, Rajinder Sharma, Marianne Øksnes, Anders Kjellevold Storesund, Solveig Moss Kolseth

“…It was complicated by thrombotic occlusion of the upper venous system, repeated postoperative bleedings and critical illness neuropathy. …”
Get full text

Influence of strength and power training on the rate of force development, peak force and functional mobility in elderly people with Parkinson's disease: a randomized controlled tr... by Késia Maísa do Amaral Felipe, Késia Maísa do Amaral Felipe, Patrícia de Aguiar Yamada, Tamires Meneghetti, Flávia Roberta Faganello-Navega, Flávia Roberta Faganello-Navega

“…Next, the participants underwent lower limbs muscle strength or muscle power training for eight consecutive weeks twice a week and were then re-evaluated.ResultsThe repeated measures ANOVA test showed a significant difference for PF, RFD and FM regardless of training type.ConclusionThe proposed muscle strength and muscle power training protocols influenced the increase in RFD, PF and FM of all participants; however, the increase in RFD in the first 200 ms was more pronounced in the groups submitted to power training and the increase in PF was more pronounced in the groups submitted to strength training.…”
Get full text

Neuromuscular electrical stimulation training induces myonuclear accretion and hypertrophy in mice without overt signs of muscle damage and regeneration by Aurélie Fessard, Aliki Zavoriti, Natacha Boyer, Jules Guillemaud, Masoud Rahmati, Peggy Del Carmine, Christelle Gobet, Bénédicte Chazaud, Julien Gondin

“…Methods Contractile activity was generated by applying repeated electrical stimuli over the mouse plantar flexor muscles. …”
Get full text

Instability of revised Korean Developmental Screening Test classification in first year of life by Ji Eun Jeong, You Min Kim, Na Won Lee, Gyeong Nam Kim, Jisuk Bae, Jin Kyung Kim

“…Conclusion Infants scoring below -2 SD on the revised K-DST 4–5 months questionnaire, especially in the gross motor domain, should undergo close monitoring and repeated evaluations in the absence of neurological abnormalities or developmental red flags.…”
Get full text

Perception of antibiotic use and antibiotic resistance among faculty and staff in a medical school: insights from a mixed mode survey in Bahrain by Ronni Mol Joji, Archana Prabu Kumar, Amer Almarabheh, Ali Al-Mahmeed, Mohd Shadab, Khalid Bindayna, Mohammad Shahid

“…When it comes to consequences of ABR, participants mentioned the risk of repeated infection and spread of stronger strains of bacteria that might be difficult to treat soon. …”
Get full text

Sunscreen Use among a Population of Saudi University Students by Mohammed I. AlJasser, Abdullah Aljumah, Mohannad Alzaydi, Abdullah Alassaf, Suliman Alassafi, Maha T. Alassafi, Mohammed Almedlej, Emad Masuadi

“…Most students apply sunscreen less than 10 minutes before going out and do not repeat the application throughout the day. More than 90% of students seem to apply insufficient amount of sunscreen. …”
Get full text

Local application of sodium thiosulfate as an otoprotectant for cisplatin-exposed patients – A narrative literature review to explore the potential benefit for children with cancer... by Nienke Streefkerk, Amirhossein Masroor, James I. Geller, Martine van Grotel, Marc Ansari, Eric Bouffet, Archie Bleyer, Brice Fresnau, Michael Sullivan, Alwin D.R. Huitema, Alexander E. Hoetink, Per Kogner, Rudolf Maibach, Allison F. O’Neill, Vassilios Papadakis, Kaukab M. Rajput, Gareth J. Veal, Penelope R. Brock, Annelot J.M. Meijer, Marry M. van den Heuvel-Eibrink

“…The burden and potential sequalae of repeated intratympanic procedures in children, together with the low level of evidence of efficacy, currently limited to pre-clinical data, suggests that further study and potentially improved technology to apply local STS is required for childhood cancer patients receiving cisplatin.…”
Get full text

TARGET Protein: the effect of augmented administration of enteral protein to critically ill adults on clinical outcomes—statistical analysis plan for a cluster randomized, cross-se... by Sophie Zaloumis, Matthew J. Summers, Jeffrey J. Presneill, Rinaldo Bellomo, Lee-anne S. Chapple, Marianne J. Chapman, Adam M. Deane, Suzie Ferrie, Craig French, Sally Hurford, Nima Kakho, Matthew J. Maiden, Stephanie N. O’Connor, Sandra L. Peake, Emma J. Ridley, An Tran-Duy, Patricia J. Williams, Paul J. Young, Amalia Karahalios, on behalf of the TARGET Protein Investigators, the Australian, New Zealand Intensive Care Society Clinical Trials Group

“…Each ICU received one trial formula for a 3-month period and then switched to the alternate formulae. This sequence was repeated, for a total trial length of 12 months. The primary outcome is the number of days free of the index hospital and alive at day 90. …”
Get full text

Elevated mepolizumab levels in patients with severe asthma responsive to 1 year’s mepolizumab treatment by Takayasu Nishimaki, MD, Hitoshi Sasano, MD, PhD, Sonoko Harada, PhD, Tomohito Takeshige, MD, PhD, Yuuki Sandhu, MD, PhD, Yuki Tanabe, MD, Kei Matsuno, MD, PhD, Tetsutaro Nagaoka, MD, PhD, Jun Ito, MD, PhD, Ryo Atsuta, MD, PhD, Mayu Ohuchi, PhD, Shigehiro Yagishita, MD, PhD, Akinobu Hamada, PhD, Kazuhisa Takahashi, MD, PhD, Norihiro Harada, MD, PhD

“…Baseline assessments were conducted and repeated at 3, 6, and 12 months. Those with response were categorized on the basis of improvements in asthma control test score, lung function, and asthma exacerbations. …”
Get full text

Growth of the prefrontal cortical glioblastoma altered cognitive and emotional behaviors via mediating miRNAs and GABA-A receptor signaling pathways in rats by Sepide Nateghi, Ameneh Rezayof, Fatemeh Kouhkan, Ladan Delphi, Yavar Bagheri Davisaraei, Fatemeh Rostami, Fatemeh Tirgar, Houri Sepehri

“…The implantation of C6 cells into the mPFC induced GBM in this brain region (referred to as the mPFC-GBM) in male Wistar rats via stereotaxic surgery, as confirmed by Magnetic Resonance Imaging (MRI), and Hematoxylin and Eosin (H&E) staining. Repeated microinjections of muscimol, a potent GABAA receptor agonist, directly into the mPFC-GBM (1 µg/rat/2.5 μl) following tumor induction decreased tumor volume and weight, resulting in an increased survival rate. …”
Get full text

Sigmoid Volvulus in Pregnancy Assessed by Contrast-Enhanced Computed Tomography Scanning by Toshiaki Watanabe, Tadatsugu Kinjo, Yoshino Kinjyo, Hayase Nitta, Hitoshi Masamoto, Keiko Mekaru, Yoichi Aoki

“…The patient was a 19-year-old primiparous woman. She complained of repeated exacerbations and remissions of abrupt lower abdominal pain for the past 2 days and was transported to our hospital at 33 weeks of gestation. …”
Get full text

Feasibility of Right Upper Transversal Hepatectomy in the Absence of an Inferior Right Hepatic Vein: New Insights regarding This Complex Procedure by Fabio Ferrari Makdissi, Jaime Arthur Pirola Kruger, Vagner Birk Jeismann, Paulo Herman

“…Maximum parenchyma preservation might prevent postoperative liver failure and allow repeated resections in case of hepatic recurrence.…”
Get full text