Chromogranin A: From Laboratory to Clinical Aspects of Patients with Neuroendocrine Tumors by Paola Di Giacinto, Francesca Rota, Laura Rizza, Davide Campana, Andrea Isidori, Andrea Lania, Andrea Lenzi, Paolo Zuppi, Roberto Baldelli

“…An open-label, phase II trial assesses the clinical activity of long-acting repeatable pasireotide in treatment-naive patients with metastatic grade 1 or 2 NETs. …”
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Understanding the Spectrum of Mild Clinical Outcomes and Novel Findings in Arterial Tortuosity Syndrome Among Qatari Patients: Implications of SLC2A10 Mutation by Muhammed Riyas K. Rahmath, Haytham Ibrahim, Muhammad Faiyaz-Ul-Haque, Zafar Nawaz, Ahmad Zitoun, Ahmed Hussein, Ahmed Sadek, Ayman El-Menyar, Reema Kamal, Hassan Al-Thani, Gulab Sher

“…These findings underscore the importance of effective education strategies through repeated counseling aimed at preventing cousin marriage and the syndrome within the cohort.…”
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Sentinel-1-Aided Mutual Calibration of TanDEM-X DEMs for the Estimation of Height and Volume Changes by Carolina Gonzalez, Luca Dell'Amore, Jose-Luis Bueso-Bello, Pietro Milillo, Gabriele Schwaizer, Thomas Nagler, Paola Rizzoli

“…In this article, we present a novel technique for performing an automatic selection of reliable natural tie-points from Sentinel-1 repeat-pass time-series, by exploiting persistent scatterers candidates, and we discuss their applicability to TanDEM-X data. …”
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Mutated p53 Promotes the Symmetric Self-Renewal of Cisplatin-Resistant Lung Cancer Stem-Like Cells and Inhibits the Recruitment of Macrophages by Yu Xu, Zhi Xu, Qi Li, Liang Guo, Yao Wang, Jianchun Zhou, Guansong Wang, Yuliang Liu

“…Cisplatin-resistant lung cancer cells with different TP53 backgrounds were generated in vitro by exposing A549, H460, and H661 lung cancer cell lines repeatedly to cisplatin. CD44+/CD90+ stem-like cells were identified in above cisplatin-resistant lung cancers (termed as cisplatin-resistant lung cancer stem-like cells, (Cr-LCSCs)) and stained with PKH26 dye which was used to define the self-renewal pattern. …”
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Age and Sex Variation in the Duration of Action and Corneal Touch Threshold (CTT) following Instillation of 0.5% Topical Ophthalmic Proparacaine and Tetracaine Hydrochlorides by Samuel Kyei, Nana Yaw Abaka Dadzie, Ebenezer Zaabaar, Kwasi Antwi Asamoah Dwomoh, Kofi Asiedu

“…CTT and duration of action of the ophthalmic solutions were tested for statistical significance using repeated measures ANOVA. Results. The total duration of effect was 20 minutes for females and 25 minutes for males for both anesthetics. …”
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Critical factors influencing live birth rates in fresh embryo transfer for IVF: insights from cluster ensemble algorithms by Zheng Yu, Xiaoyan Zheng, Jiaqi Sun, Pengfei Zhang, Ying Zhong, Xingyu Lv, Hongwen Yuan, Fanrong Liang, Dexian Wang, Jie Yang

“…Assisted reproductive technology (ART) assists numerous infertile couples in conceiving, yet some experience repeated, unsuccessful cycles. This study aims to identify the pivotal clinical factors influencing the success of fresh embryo transfer of in vitro fertilization (IVF). …”
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Differentiation of Rat Adipose-Derived Stem Cells into Parathyroid-Like Cells by Ping Zhang, Hao Zhang, Wenwu Dong, Zhihong Wang, Yuan Qin, Changhao Wu, Qi Dong

“…The current treatment for postoperative hypoparathyroidism has shortcomings, such as repeated blood monitoring for dosage adjustment, uncertain long-term efficacy, and the high price of recombinant parathyroid hormone therapy. …”
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Formation of Stripped Stars from Stellar Collisions in Galactic Nuclei by Charles F. A. Gibson, Fulya Kiroğlu, James C. Lombardi Jr., Sanaea C. Rose, Hans D. Vanderzyden, Brenna Mockler, Monica Gallegos-Garcia, Kyle Kremer, Enrico Ramirez-Ruiz, Frederic A. Rasio

“…Lastly, we discuss how the extended collision products, with high central to average density ratios, can be related to repeated partial TDEs like ASASSN-14ko and G objects in the Galactic center.…”
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Effects of low, moderate, and high-intensity aquatic exercise on joint edema in induced rat knee arthritis by Alline Mardegan Mioto, Daniel Fernando dos Reis, Thiago Alves Garcia, Guilherme Akio Tamura Ozaki, Iara Buriola Trevisan, Rodrigo Metzker Pereira Ribeiro, Robson Chacon Castoldi, José Carlos Silva Camargo Filho

“…Weight changes: Student’s T-test or ANOVA for repeated measurements, with Bonferroni's post-test for inter-week and first and last-week comparisons within each group. …”
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Genetic Characteristics of the Rat Fibroblast Cell Line Rat-1 by Thomas Liehr, Stefanie Kankel, Eva Miriam Buhl, Sarah K. Schröder-Lange, Ralf Weiskirchen

“…While some cytogenetic information on their basic chromosomal features is available, detailed genomic analyses, such as karyotype analysis, short tandem repeat (STR) profiling, and whole-genome sequencing, have not been thoroughly conducted. …”
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Ultrasound-guided Hydrostatic Reduction of Acute Intussusception in Children at a Tertiary Care Center: An Observational Study by Ajay Kumar Yadav, Neha Yadav, Binit Dev, Sonia Dahal, Rohit Prasad Yadav, Sushil Taparia, Hiramani Pathak

“…Among successful reductions, 3 (3.84%) patients had recurrence and repeat successful hydrostatic reduction was done. …”
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An open-label study evaluating the safety and efficacy of AMO-01 for the treatment of seizures in Phelan-McDermid syndrome by Tess Levy, J. Lloyd Holder, Jr., Joseph P. Horrigan, Michael F. Snape, Alison McMorn, Christina Layton, Hailey Silver, Kate Friedman, Hannah Grosman, Slayton Underwood, Danielle Halpern, Jessica Zweifach, Paige M. Siper, Alexander Kolevzon

“…Future placebo-controlled studies with larger sample sizes and repeated dosing are warranted.…”
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A Novel Construction of Substitution Box Based on Polynomial Mapped and Finite Field With Image Encryption Application by Abid Mahboob, Muhammad Asif, Imran Siddique, Aysha Saleem, Muhammad Nadeem, Dariusz Grzelczyk, Jan Awrejcewicz

“…To keep the S-box bijective, swap each missing entries with repeating entries after that we acquire the initial box. …”
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Single or multiple treatments with lusutrombopag in subjects with thrombocytopenia and chronic liver disease needing an invasive procedure by Davide Scalabrini, Paolo Sciuto, Cristina Felicani, Antonia Rudilosso, Pietro Andreone

“…These two cases show how a short course of lusutrombopag allows to safely perform one or more invasive procedures and how the administration of the drug can be repeated without losing efficacy. Furthermore, this drug shows an excellent safety profile and avoids the risks of platelet transfusion. …”
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An electrolyte-gated transistor for the monitoring of a CRISPR/Cas activity by Pierre Guermonprez, Le Tu Anh, Louis Renaud, Pierre Nioche, Eric Krejci, Aurélie Alleaume-Butaux, Nicolas Battaglini, Vu Thi Thu, Sébastien Sanaur, Benoît Piro

“…Reverse transcriptase-polymerase chain reaction (RT-PCR) remains the gold standard, but clustered regularly interspaced short palindromic repeats linked to a Cas endoribonuclease particle (CRISPR/Cas) have recently revolutionized the recognition step of two RNAs, i.e. the CRISPR-RNA (crRNA) and the target, providing a much better selectivity compared to the naked hybridization on which RT-PCR is based. …”
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Aspiration of acidified milk induces milk allergy by activating alveolar macrophages in mice by Akiko Nakaoka, Takayasu Nomura, Atsushi Suzuki, Kazuyoshi Ozeki, Hirohito Kita, Shinji Saitoh

“…Methods: Mice were exposed to cow's milk (CM) treated with hydrochloric acid through repeated aspiration into their airways. Subsequently, they were challenged by intraperitoneal injection of CM extract. …”
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Multiple pathways to evaluate the immunoprotective effect of Turkeys Herpesvirus recombinant vaccine expressing HA of H9N2 by Wenhao Yang, Jin Zhang, Jing Dai, Mengjiao Guo, Xiaolong Lu, Ruyi Gao, Kaituo Liu, Min Gu, Shunlin Hu, Xiufan Liu, Xiaoquan Wang, Xiaowen Liu

“…In this study, a recombinant Herpesvirus of Turkeys (HVT) vaccine expressing H9-HA was constructed using Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) technology. In the construction of HVT-EGFP-HA recombinant virus, nonhomologous end joining (NHEJ) is a much more efficient strategy compare to Homology-directed recombination (HDR). …”
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RNA-Targeting CRISPR/CasRx system relieves disease symptoms in Huntington’s disease models by Yingqi Lin, Caijuan Li, Yizhi Chen, Jiale Gao, Jiawei Li, Chunhui Huang, Zhaoming Liu, Wei Wang, Xiao Zheng, Xichen Song, Jianhao Wu, Jiaxi Wu, Oscar Junhong Luo, Zhuchi Tu, Shihua Li, Xiao-Jiang Li, Liangxue Lai, Sen Yan

“…Abstract Background HD is a devastating neurodegenerative disorder caused by the expansion of CAG repeats in the HTT. Silencing the expression of mutated proteins is a therapeutic direction to rescue HD patients, and recent advances in gene editing technology such as CRISPR/CasRx have opened up new avenues for therapeutic intervention. …”
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A Comparative Analysis of the Water Retention Properties of Hydrogels Prepared from Melon and Orange Peels in Soils by Shiwei Fang, Yuan Zhong, Jun Wu, Yufan Xie, Liqun Cai, Minjun Li, Jun Cao, Hejie Zhao, Bo Dong

“…The degree of swelling was 84.0 g/g when the process was repeated seven times. After the MP-gels were applied to the soil, it was observed that the gels enhanced the water retention and holding capacity of the sandy soil. …”
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3D Crystal Construction by Single‐Crystal 2D Material Supercell Multiplying by Wenhao Li, Jichuang Shen, Yaqing Ma, Xiang Xu, Han Chen, Lida Yu, Chen Ji, Menglin He, Kezhao Ma, Yiwei Duo, Li Wang, Tongbo Wei, Liping Shi, Muhong Wu, Kaihui Liu, Huaze Zhu, Wei Kong

“…In this study, a supercell multiplying approach is introduced that enables high‐throughput construction of 3D superstructures on a macroscopic scale, utilizing artificially stacked single‐crystalline 2D multilayers as foundational repeating units. By employing wafer‐scale single‐crystalline 2D materials and referencing the crystal orientation of substrates, the method ensures precise alignment of crystal orientation within and across each supercell, thereby achieving controllable periodicity along all three axes. …”
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