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2481
Apaf-1 is an evolutionarily conserved DNA sensor that switches the cell fate between apoptosis and inflammation
Published 2025-01-01“…Mechanistically, mammalian Apaf-1 recruits receptor-interacting protein 2 (RIP2, also known as RIPK2) via its WD40 repeat domain and promotes RIP2 oligomerization to initiate NF-κB-driven inflammation upon cytoplasmic DNA recognition. …”
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2482
Clozapine-Induced Cardiotoxicity Presenting as Sepsis: A Case Report and Literature Review
Published 2019-01-01“…Clozapine was immediately discontinued, and his repeat echocardiogram showed normalization of his systolic function. …”
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2483
Catalytic degradation of dyes using gold nanoparticles supported over chitosan coated cotton cloth composite
Published 2025-01-01“…The recyclability of the catalyst was demonstrated by repeatedly recovering and reusing it in three successive cycles. …”
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2484
Molecular characterization, DNA fingerprinting and genetic diversity analysis of Nepalese rice landraces using SSR markers
Published 2024-12-01“…This study aimed to identify the variability in 80 rice landraces using 19 simple sequence repeat (SSR) markers. The collection represented geographical regions suitable for rice farming in Nepal. …”
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2485
Seismic Behavior and Finite Element Analysis of Reinforced Concrete Short Columns Impacted by Oblique Earthquakes
Published 2020-01-01“…The studied parameters include the loading angle, axial compression ratio, the high-strength stirrups with small spacing, and the carbon-fiber-reinforced polymer (CFRP) wrapped column end or outer steel plate mesh at the end of the column. Low-cycle repeated loading tests were used to analyze the specimens’ seismic performance indices of hysteretic behavior, strength, stiffness, deformation capacity, and energy dissipation capacity. …”
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2486
Screening and characterization of the scFv for chimeric antigen receptor T cells targeting CEA-positive carcinoma
Published 2023-05-01“…While C2-45 resulted in almost no tumor lysis or IFN-γ release. In a repeat CEA antigen stimulation assay, M5A showed the best cell proliferation and cytokine secretion levels. …”
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2487
Simultaneous Adsorption and Photocatalytic Degradation of Malachite Green Using Electrospun P(3HB)-TiO2 Nanocomposite Fibers and Films
Published 2011-01-01“…The concentration of Ti in cast P(3HB)-50 wt% TiO2 film was found to decrease significantly during the repeated usage. The electrospun P(3HB)-50 wt% TiO2 film has high potency as an efficient and inexpensive yet simple method for the dye effluent decolorization, degradation, and detoxification.…”
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2488
Challenges and strategies in the soluble expression of CTA1-(S14P5)4-DD and CTA1-(S21P2)4-DD fusion proteins as candidates for COVID-19 intranasal vaccines.
Published 2024-01-01“…In this study, we constructed two fusion proteins containing CTA1, tandem repeat linear epitopes of the SARS-CoV-2 spike protein (S14P5 or S21P2), and DD. …”
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2489
Stepping in Place While Voluntarily Turning Around Produces a Long-Lasting Posteffect Consisting in Inadvertent Turning While Stepping Eyes Closed
Published 2016-01-01“…The posteffects are possibly dependent on the repeated voluntary contraction of leg and foot intrarotating pelvic muscles that rotate the trunk over the stance foot, a synergy common to both protocols. …”
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2490
Développer le désert : anciennes et nouvelles utopies
Published 2011-12-01“…In both the religious traditions of the Mediterranean and under the successive labels of "progress", "development" and "globalization", the idea of civilization has repeatedly found its opposite, its enhancer and its complement when referring to the desert: when civilization fails to conquer the desert, it reverts to desert. …”
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2491
Transportation Infrastructure Project Financing; Highways Capital Structure Design Techniques
Published 2021-01-01“…The global infrastructure sector is witnessing the continued growth of a private equity fund of mezzanine tools. Repeated use of potential claims embedded in mezzanine financing has invalidated the traditional model for optimizing capital structure.…”
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2492
Spontaneous Loculated Pneumomediastinum in a COVID-19-Infected Patient
Published 2022-01-01“…By day 4, imaging was repeated, performed due to exacerbation of pleuritic chest pain, decreased O2 saturation (80%), and coughing that revealed multiple ground-glass opacities bilaterally, and interlobular septal thickening with emphysema in most of the left upper lobe and a small part of right upper lobe which led to severe spontaneous left pneumomediastinum and parenchymal consolidation was also observed. …”
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2493
Neurotoxicological manifestations among drug abusers admitted to Alexandria poison unit and Al-Mamora hospital: prospective study
Published 2024-12-01“…Most patients were single, educated, unemployed, or working in skilled labor. Smoking and repeated relapses were common, highlighting the chronic and challenging nature of drug abuse.Conclusion: Drug abuse is a persistent problem requiring community awareness and collaboration among ministries. …”
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2494
Between Flogging and Imprisonment: The Disparity Effect of the Sharia Court's Decision on the Supremacy of the Qanun Jinayat of Aceh
Published 2024-10-01“…Then, the perpetrator immediately returns to society and has an opportunity to repeat his crimes, while the victim is still in a traumatized state.…”
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2495
A comparative assessment of machine learning models and algorithms for osteosarcoma cancer detection and classification
Published 2025-06-01“…The performance differences between the learned ML models were then validated using repeated stratified 10-fold cross-validation and 5x2 cross-validation paired t-tests to select the best model for our task. …”
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2496
Microwave System: A Novel Treatment for Localized Adiposity Reduction in a Latin American Population
Published 2023-01-01“…Data descriptive analysis was made as well as single-factor repeated measures ANOVA to show pre- and post-treatment difference, and mixed ANOVA for body mass index (BMI) subgroup analysis was performed. …”
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2497
Joint Effects of Physical Activity and BMI on Risk of Hypertension in Women: A Longitudinal Study
Published 2014-01-01“…Generalised estimating equation models for binary repeated measures were performed to determine the individual and joint effects of BMI and physical activity on incident hypertension. …”
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2498
Antibody to Hepatitis C Virus in Risk Groups in Canada
Published 1992-01-01“…The prevalence of antibodies against hepatitis C virus (HCV) was studied in hemophiliacs, hemodialysis patients, intravenous drug abusers, female prisoners, homosexuals, individuals with no markers of recent hepatitis A or B virus infections and normal individuals (federal public servants), by an enzyme immunoassay (Ortho Diagnostic Systems Inc). Repeat positive samples were further tested by recombinant immunoblot assay (RIBA) HCV (Chiron Corp, California). …”
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2499
In-season whole-body vibration training enhances vertical jump performance in professional soccer goalkeepers
Published 2017-08-01“…Vertical jump performance, initiated from the goalkeepers’ individual ready position, was measured prior to, and on completion of, the five-week study. A 2-way ANOVA with repeated measures showed an improvement in the experimental group’s jump performance from 49.2 ± 4.4 cm pre-training to 53.8 ± 3.5 cm post-training, while the control group’s performance remained stable from 47.02 ± 4.8 cm pre-training to 46.6 ± 4.5 cm post-training, resulting in a significant time-by-group interaction (P lt;0.001). …”
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2500
Abnormal link detection algorithm based on semi-local structure
Published 2022-02-01“…With the research in network science, real networks involved are becoming more and more extensive.Redundant error relationships in complex systems, or behaviors that occur deliberately for unusual purposes, such as wrong clicks on webpages, telecommunication network spying calls, have a significant impact on the analysis work based on network structure.As an important branch of graph anomaly detection, anomalous edge recognition in complex networks aims to identify abnormal edges in network structures caused by human fabrication or data collection errors.Existing methods mainly start from the perspective of structural similarity, and use the connected structure between nodes to evaluate the abnormal degree of edge connection, which easily leads to the decomposition of the network structure, and the detection accuracy is greatly affected by the network type.In response to this problem, a CNSCL algorithm was proposed, which calculated the node importance at the semi-local structure scale, analyzed different types of local structures, and quantified the contribution of edges to the overall network connectivity according to the semi-local centrality in different structures, and quantified the reliability of the edge connection by combining with the difference of node structure similarity.Since the connected edges need to be removed in the calculation process to measure the impact on the overall connectivity of the network, there was a problem that the importance of nodes needed to be repeatedly calculated.Therefore, in the calculation process, the proposed algorithm also designs a dynamic update method to reduce the computational complexity of the algorithm, so that it could be applied to large-scale networks.Compared with the existing methods on 7 real networks with different structural tightness, the experimental results show that the method has higher detection accuracy than the benchmark method under the AUC measure, and under the condition of network sparse or missing, It can still maintain a relatively stable recognition accuracy.…”
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