Impact of kidney volume on incidence of in-hospital kidney-related adverse outcomes in patients with acute heart failure by Akira Saito, Taku Asano, Nobuyuki Komiyama, Sachiko Ohde

“…We defined the composite of death from any cause, initiating renal replacement therapy, and WRF during hospitalization as major adverse kidney events (MAKE). …”
Get full text

Comparison of citrate dialysate in pre- and post-dilution online hemodiafiltration: effect on clot formation and adequacy of dialysis in hemodialysis patients by Pasu Nakornchai, Arisara Jitraree, Monpinya Charttong Homjan, Thanachit Laykhram, Thananda Trakarnvanich

“…Background Citrate dialysate (CD) has been successfully used in conventional hemodialysis and continuous renal replacement therapy; however, no study has compared pre- and post-dilution online hemodiafiltration (oL-HDF). …”
Get full text

Bias-corrected serum creatinine from UK Biobank electronic medical records generates an important data resource for kidney function trajectories by Mathias Gorski, Simon Wiegrebe, Ralph Burkhardt, Merle Behr, Helmut Küchenhoff, Klaus J. Stark, Carsten A. Böger, Iris M. Heid

“…This included 206,063 individuals with ≥ 2 assessments over up to 60.2 years (median 6.00 assessments, median time = 8.7 years), where we also obtained eMR-based information on kidney disease or renal replacement therapy. We found an annual eGFR decline of 0.11 (95%-CI = 0.10–0.12) versus 1.04 mL/min/1.73m2/year (95%-CI = 1.03–1.05) without and with bias-correction, the latter being in line with literature. …”
Get full text

Early versus late nephrology referral and patient outcomes in chronic kidney disease: an updated systematic review and meta-analysis by Linan Cheng, Nan Hu, Di Song, Li Liu, Yuqing Chen

“…Conclusions Our study showed a lower risk of mortality, shorter lengths of initial hospitalization, and better preparations for renal replacement therapy among patients referred early to nephrologists. …”
Get full text

Cost-effectiveness of Chloride-liberal versus Chloriderestrictive Intravenous Fluids among Patients Hospitalized in the United States by Louise Perrault, Dilip Makhija, Idal Beer, Suzanne Laplante, Sergio Iannazzo, Karthik Raghunathan

“…**Background:** Patients developing acute kidney injury (AKI) during critical illness or major surgery are at risk for renal sequelae such as costly and invasive acute renal replacement therapy (RRT) and chronic dialysis (CD). …”
Get full text

The Probe for Renal Organic Cation Secretion (4-Dimethylaminostyryl)-N-Methylpyridinium (ASP+)) Shows Amplified Fluorescence by Binding to Albumin and Is Accumulated In Vivo by Jacob Schade Engbjerg, Vincenzo Costanzo, Donato Sardella, Luca Bordoni, Steen Jakobsen, Luciano D'Apolito, Jørgen Frøkiær, Francesco Trepiccione, Giovambattista Capasso, Sebastian Frische

“…Accumulation of uremic toxins may lead to the life-threatening condition “uremic syndrome” in patients with advanced chronic kidney disease (CKD) requiring renal replacement therapy. Clinical evaluation of proximal tubular secretion of organic cations (OC), of which some are uremic toxins, is desired, but difficult. …”
Get full text

Improved Outcome of Severe Acute Pancreatitis in the Intensive Care Unit by Polychronis Pavlidis, Siobhan Crichton, Joanna Lemmich Smith, David Morrison, Simon Atkinson, Duncan Wyncoll, Marlies Ostermann

“…Among hospital survivors, 27.5% developed diabetes mellitus and 5% needed long-term renal replacement therapy. Conclusions. The outcome of patients with SAP in ICU was better than previously reported but associated with a resource demanding hospital stay and long-term morbidity.…”
Get full text

Lupus activity in lupus nephritis patients with end-stage renal disease treated with hemodialysis by Caroline Samy Morad, Shams ElDoha Galal Zaiema, Eman Ahmed Hafez, Mohammed Maher Mohammed Mohammed Mansour, Amr Elsayed Mohammed Abd-Allah Khalil, Shaymaa Gamal Arafa Hassan

“…Abstract Background Lupus nephritis is one of the major causes of ESRD, which may necessitate renal replacement therapy, especially hemodialysis. Evaluating post-HD lupus flares in LN patients is pivotal in improving their outcomes. …”
Get full text

The clinical features and outcomes of diabetes patients infected with COVID-19: a systematic review and meta-analysis comprising 192,693 patients by Kai Liu, Shu Liu, Ting-ting Xu, Hong Qiao

“…Compared with the non-diabetic group, the diabetic group had a higher incidence of complications in acute respiratory distress syndrome (ARDS), shock, acute heart injury, acute kidney injury and more regularly used oxygen therapy, invasive ventilation, non-invasive ventilation, continuous renal replacement therapy (CRRT), extracorporeal membrane oxygenation (ECMO) treatment. …”
Get full text

Evaluating the effects of continuous veno-venous hemodiafiltration on O2 and CO2 removal and energy expenditure measurement using indirect calorimetry by Weronika Wasyluk, Robert Fiut, Marcin Czop, Agnieszka Zwolak, Wojciech Dąbrowski, Manu L N G Malbrain, Joop Jonckheer

“…This study aims to evaluate the effects of CVVHDF on O₂ and CO₂ removal and the accuracy of REE measurement using IC in patients undergoing continuous renal replacement therapy. Design Prospective, observational, single-center study. …”
Get full text

Analysis of clinical characteristics of hemorrhagic fever with renal syndrome with acute pancreatitis: a retrospective study by Lihua Huang, Min Xiao, Xiaoling Huang, Jun Wu, Jiao Luo, Fuxing Li, Wei Gu

“…LASSO-Logistic regression was used to screen risk factors and develop a nomogram model.Results After PSM, HFRS patients with AP had higher rates of Continuous Renal Replacement Therapy (CRRT) and/or mechanical ventilation use, , ICU admission, and 30-day mortalitycompared with those without AP (p < 0.05). …”
Get full text

Association between the triglyceride–glucose index and the risk of acute kidney injury in critically ill patients with acute pancreatitis: a retrospective study by Zheng Wang, Haoyu Zhang, Xiaozhou Xie, Jie Li, Yuchen Jia, Jiongdi Lu, Chongchong Gao, Feng Cao, Fei Li

“…The secondary endpoint was in-hospital mortality and the rate of renal replacement therapy(RRT) use. Cox regression analysis and restricted cubic spline were used to analyze TyG index association with AKI risk. …”
Get full text

The Urinary Liver-Type Fatty Acid Binding Protein (L-FABP) in Early Detection and Outcome Prediction of Sepsis-Associated Acute Kidney Injury by Ghi Nguyen Hai, Binh Nguyen Gia, Hoa Do Thanh, Cuong Nguyen Thai, Duc Vu Anh, Anh Duong Duc, Duong Le Xuan Xuan

“…The screening performance characteristics of urinary L-FABP in early detection of AKI within seven days of admission and need for renal replacement therapy (RRT) were calculated and reported. …”
Get full text

Association between normal saline infusion volume in the emergency department and acute kidney injury in heat stroke patients: a multicenter retrospective study by Lan Chen, Junlu Zhao, Liyun Lu, Zhumei Gong, Shuying Xu, Xiaoling Yang, Yuping Zhang, Xiuqin Feng

“…Secondary outcomes included the need for continuous renal replacement therapy (CRRT), admission to the intensive care unit (ICU), length of stay in the ICU and hospital, and in-hospital mortality. …”
Get full text

The clinical characteristics and implications of acute kidney injury during induction therapy for acute promyelocytic leukemia by Kai Shen, Chenlu Yang, Jie Huang, Xiao Shuai, Ting Niu, Hongbing Ma

“…Among them, eight patients received continuous renal replacement therapy, and 3/8 patients experienced early death (ED), which was defined as death within 3 months of diagnosis. …”
Get full text

Podocyturia: A Clue for the Rational Use of Amiloride in Alport Renal Disease by H. Trimarchi, R. Canzonieri, A. Muryan, A. Schiel, A. Araoz, M. Paulero, J. Andrews, T. Rengel, M. Forrester, F. Lombi, V. Pomeranz, R. Iriarte, E. Zotta

“…Kidney failure is usually a major complication of the disease, and patients require renal replacement therapy early in life. Microhematuria and subsequently proteinuria are hallmarks of kidney involvement, which are due to primary basement membrane alterations that mainly cause endothelial thrombosis and podocyte contraction and ulterior irreversible detachment. …”
Get full text

Development of Prone Position Ventilation Device and Study on the Application Effect of Combined Life Support Technology in Critically Ill Patients by Yufeng Li, Qiaoqiao Hu, Wenjie Wang, Changhong Du, Siwen Fan, Linlin Xu, Songmei Li, Bei Chen

“…A subset of patients in each group also received life support technologies such as extracorporeal membrane oxygenation (ECMO) and continuous renal replacement therapy (CRRT). We assessed prone position ventilation tolerance, oxygen saturation increments postintervention, duration of prone positioning, CRRT filter lifespan, and the incidence of adverse events. …”
Get full text

Long-term mortality in patients with end-stage renal disease undergoing hemodialysis and peritoneal dialysis: a propensity score matching retrospective study by Pengjie Zhang, Liru Xun, Nan Bao, Ding Tong, Bin Duan, Du Peng

“…This study aimed to investigate the differences in survival and the factors that influence it in patients with end-stage renal disease treated with HD or PD.Methods We retrospectively analyzed factors related to all-cause death with renal replacement therapy and compared the long-term mortality between HD and PD strategies in patients with ESRD who started HD or PD treatment in our renal HD center between January 1, 2008, and December 1, 2021.Results Overall, 1,319 patients were included, comprising 690 and 629 patients in the HD and PD groups, respectively, according to the inclusion criteria. …”
Get full text

Plasma proteome fingerprint in kidney diseases by Kirill S. Nikolsky, Arthur T. Kopylov, Valeriya I. Nakhod, Natalia V. Potoldykova, Dmitry V. Enikeev, Tatiana V. Butkova, Liudmila I. Kulikova, Kristina A. Malsagova, Vladimir R. Rudnev, Denis V. Petrovskiy, Alexander A. Izotov, Anna L. Kaysheva

“…Patients with kidney diseases are often asymptomatic until disease progression starts. Expensive renal replacement therapy options, such as dialysis or kidney transplant, are required for end-stage kidney disease. …”
Get full text

Management of acute myocardial infarction in chronic kidney disease in Germany: an observational study by Victor Walendy, Andreas Stang, Matthias Girndt

“…Abstract Background Managing acute myocardial infarction (AMI) in patients with chronic kidney disease (CKD) or end-stage renal disease on dialysis (renal replacement therapy, RRT) presents challenges due to elevated complication risks. …”
Get full text