A Case of Alport Syndrome with Posttransplant Antiglomerular Basement Membrane Disease despite Negative Antiglomerular Basement Membrane Antibodies by EIA Treated with Plasmapheres... by Sumiko I. Armstead, Thomas Hellmark, Jorgen Wieslander, Xin J. Zhou, Ramesh Saxena, Nilum Rajora

“…Here we present a case of a 22-year-old male with end-stage renal disease secondary to Alport syndrome, with a previously failed renal allograft, who received a second deceased-donor kidney transplant. …”
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The Molecular Effects of SGLT2i Empagliflozin on the Autophagy Pathway in Diabetes Mellitus Type 2 and Its Complications by Ranin Saad, Hagar Tadmor, Offir Ertracht, Nakhoul Nakhoul, Farid Nakhoul, Farber Evgeny, Shaul Atar

“…SGLT2i significantly reduces progression of DN and onset of end-stage renal disease in T2DM patients, probably through its effect on autophagy.…”
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An Unusual Case of Ototoxicity with Use of Oral Vancomycin by Umut Gomceli, Srija Vangala, Cosmina Zeana, Paul J. Kelly, Manisha Singh

“…It has an elimination half life of 5–11 hours in patients with normal renal function. We present a rare case of ototoxicity after oral vancomycin administration and detectable serum vancomycin levels 24 hours after cessation of vancomycin. …”
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Shenshuaikang enema restores the intestinal barrier and microbiota-gut-kidney axis balance to alleviate chronic kidney disease via NF-κB pathway by Yan Ye, Yan Ye, Xiaopeng Huang, Xiaopeng Huang, Xiaopeng Huang, Xueying Li, Xueying Li, Fei Gao, Wenzhen Zhong, Anqi Tang, Anqi Tang, Liangbin Zhao, Dengpiao Xie, Naijing Ye, Naijing Ye

“…Finally, 16S rRNA amplicon sequencing was used to monitor changes in intestinal flora in CKD patients before and after SSKE treatment.ResultsWe found that SSKE improves renal function, attenuates renal fibrosis, reduces inflammatory factor levels, and decreases damage to intestinal and renal structures in adenine-induced CKD rats. …”
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A Case of Chronic Ethylene Glycol Intoxication Presenting without Classic Metabolic Derangements by Stephanie M. Toth-Manikowski, Hanni Menn-Josephy, Jasvinder Bhatia

“…Kidney biopsy was critical to the elucidation of the cause of his worsening renal function.…”
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A Rare Case of Isolated Ureteral Diaphragmatic Herniation: Case Report and Review of Literature by Nassib Abou Heidar, Hussein Elsemesmani, Ahmad Elamine, Mustafa Natout

“…Diaphragmatic ureteral hernias are rare causes of ipsilateral renal obstruction. Management strategies varies from conservative to ureteral stenting to operative herniorraphy and reduction. …”
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A Pediatric Case of Diffuse Alveolar Hemorrhage Secondary to Poststreptococcal Glomerulonephritis by Alison Markland, Gregory Hansen, Anke Banks, Rajni Chibbar, Darryl Adamko

“…We propose that her rapid improvement in clinical status was due to her treatment, continuous renal replacement therapy (CRRT). This mechanism would have impacted recovery by removing factors such as endothelial microparticles, superantigens, and immune complexes that have been postulated as the pulmonary-renal link. …”
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Nephrotic Syndrome in Children: From Bench to Treatment by J.-C. Davin, N. W. Rutjes

“…INS is defined by the association of the clinical features of NS with renal biopsy findings of minimal changes, focal segmental glomerulosclerosis (FSGS), or mesangial proliferation (MP) on light microscopy and effacement of foot processes on electron microscopy. …”
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Focal Segmental Glomerulosclerosis in Waldenström’s Macroglobulinemia by Akshee Batra, Shatha Herz Allah, Bijin Thajudeen

“…Renal involvement in Waldenström’s macroglobulinemia is a rare manifestation. …”
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Dynamic renoscintigraphy in cardiology and cardiac surgery by V.Yu. Kundin, I.V. Noverko, A.G. Mazur

“…Calculations of the main features of quantitative and temporal parameters of renal function, steps of the the processing of diagnostic information and its practical significance are provided. …”
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Pharmacological and Pharmacodynamic Implications of Nonsteroidal Anti-Inflammatory Drug Therapy in Elderly Arthritic Patients by W Watson Buchanan

“…Physiological changes, which include reduced muscle mass, total body water and albumin levels, as well as effects on renal and hepatic function, affect pharmacokinetic factors, including absorption, distribution, biotransformation and renal clearance. …”
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Granulomatosis with Polyangiitis with Myocarditis and Ventricular Tachycardia by Ramy Magdy Hanna, Eduardo Lopez, James Wilson

“…Granulomatosis with polyangiitis (GPA), previously known as Wegener’s granulomatosis, is a pulmonary-renal syndrome affecting small and medium sized blood vessels. …”
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Endourologic Management of Upper Tract Transitional Cell Carcinoma following Cystectomy and Urinary Diversion by Jeffrey John Tomaszewski, Marc Christopher Smaldone, Michael Cecil Ost

“…With advances in endoscopic equipment and improvements in technique, conservative endourologic management via a retrograde or antegrade approach is technically feasible with acceptable outcomes in patients with bilateral disease, solitary renal units, chronic renal insufficiency, or significant medical comorbidities. …”
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Alpha 1-antitrypsin mitigates salt-sensitive hypertension in juvenile mice by reducing diacylglycerol concentrations and protein kinase C activity in kidney membranes by Yunus E. Dogan, Yunus E. Dogan, Yunus E. Dogan, Niharika Bala, Niharika Bala, Erika S. Galban, Erika S. Galban, Russell L. Lewis, Nancy D. Denslow, Sihong Song, Abdel A. Alli, Abdel A. Alli

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Balanced crystalloid versus saline for resuscitation in pediatric septic shock: a systematic review and meta-analysis by Barkhá Vijendra, Ana Beatriz Bertol, Mylena Maria Guedes de Almeida, Pedro Henrique Aquino Gil de Freitas, Áurea Maria Salomão Simão, Bianca Lisa de Faria

“…We found no statistically significant difference between groups in AKI, hospital mortality, mechanical ventilation, need for renal replacement therapy, and PICU length of stay. …”
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Estimated Glomerular Filtration Rate Correlates Poorly with Four-Hour Creatinine Clearance in Critically Ill Patients with Acute Kidney Injury by Christopher J. Kirwan, Barbara J. Philips, Iain A. M. MacPhee

“…A more accurate real-time description of renal function in AKI is needed, and some published data suggest that equations based on serum creatinine that estimate glomerular filtration rate (eGFR) can provide this. …”
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Metformin-Associated Acute Kidney Injury and Lactic Acidosis by David Arroyo, Rosa Melero, Nayara Panizo, Marian Goicoechea, Patrocinio Rodríguez-Benítez, Soledad García Vinuesa, Eduardo Verde, Alberto Tejedor, José Luño

“…We could not find any relationship between previous renal dysfunction and the outcome of the AKI. Conclusions. …”
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Epidemiology of transthyretin (ATTR) amyloidosis: a systematic literature review by Diego Delgado, Firas Dabbous, Nitin Shivappa, Faizan Mazhar, Eric Wittbrodt, Divya Shridharmurthy, Krister Järbrink

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Incidence and prognosis associated with troponin elevation after cardiac surgery: a prospective cohort study by Arthur Clement, Lee S Nguyen, Anousone Daulasim, Magali Souibri

“…However, numerous confounding elements, such as inflammation, liver and renal function biomarkers, have been associated with troponin variations. …”
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US Pilot Study of Lumbar to Sacral Nerve Rerouting to Restore Voiding and Bowel Function in Spina Bifida: 3-Year Experience by Kenneth M. Peters, Holly Gilmer, Kevin Feber, Benjamin J. Girdler, William Nantau, Gary Trock, Kim A. Killinger, Judith A. Boura

“…Urinary/bowel changes from baseline to three years were evaluated with questionnaires, voiding diaries, urodynamics (UDS), and renal function studies. Treatment response was defined as CIC ≤ once/day with stable renal function, voiding efficiency > 50%, and no worsening of motor function. …”
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