Factors affecting cadmium toxicity to rice germinated in soils collected from downstream areas of abandoned zinc mines by P. Chanpiwat, A. Numprasanthai

“…These cultivated rice grains are consumed by local residents and have increased the risk of renal dysfunction in residents. Decreasing negative health effects by reducing cadmium accumulation in rice should be considered. …”
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Inferior vena cava diameter in patients with chronic heart failure and chronic kidney disease: a retrospective study by Jianan Li, Chi Wang, Hui wu Dong, Jing Qi, Chongyou Rao, Qiuyang Li, Kunlun He

“…In subgroup analyses, there was no significant interaction in different subgroups of cardiac and renal function for the association between IVC and all-cause mortality. …”
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The clinical role of blood coagulation and platelet receptors gene allelic variants in development of cryoglobulinemic vasculitis at chronic hepatitis C by Yekaterina Ye. Starostina, M. V. Sokolova, L. M. Samokhodskaya, T. П. Rozina, T. N. Krasnova, Ye. B. Yarovaya, N. A. Mukhin

“…Patients with CGV allele C and CC homozygosity of the gene ITGB3 1565 T/C is associated to presence of renal diseases, while allele C genotypes (TC+CC) of ITGB3 1565 T/C gene is associated with involvement of muscular and nervous system. …”
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Metabolomics to Identify Unclassified Uremic Toxins: A Comprehensive Literature Review by Raymond Vanholder, Griet Glorieux, Angel Argiles, Stéphane Burtey, Gerald Cohen, Flore Duranton, Laetitia Koppe, Ziad A. Massy, Alberto Ortiz, Rosalinde Masereeuw, Dimitrios Stamatialis, Joachim Jankowski

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Developing a Label-Free Infrared Spectroscopic Analysis with Chemometrics and Computational Enhancement for Assessing Lupus Nephritis Activity by Mei-Ching Yu, Xiang-Di Huang, Chin-Wei Kuo, Kai-Fu Zhang, Ping-Chung Liang, U-Ser Jeng, Pei-Yu Huang, Frederick Wai Keung Tam, Yao-Chang Lee

“…Furthermore, this IR-based assay incorporates an innovative algorithm and our proprietary iPath software (ver. 1.0), which calculates the prognosis prediction function (PPF, Φ) from the RAD gaps of five spectral markers and correlates these with conventional clinical renal biomarkers. We propose that this algorithm-assisted, IR-based approach can augment the patient-centric care of LN patients, particularly by focusing on changes in serum IgG glycosylation.…”
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Discovery of a novel highly specific, fully human PSCA antibody and its application as an antibody-drug conjugate in prostate cancer by Xiaojie Chu, Seungmin Shin, Du-San Baek, Liyong Zhang, Alex Conard, Megan Shi, Ye-Jin Kim, Cynthia Adams, Maggie Hines, Xianglei Liu, Chuan Chen, Zehua Sun, Dontcho V. Jelev, John W. Mellors, Dimiter S. Dimitrov, Wei Li

“…PSCA is also a promising theranostic marker for a variety of other solid tumors, including pancreatic adenocarcinoma and renal cell carcinoma. Here, we identified a novel fully human PSCA antibody using phage display methodology. …”
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Research priorities for autosomal dominant polycystic kidney disease: a UK priority setting partnership by Tess Harris, Albert Ong, Paul J D Winyard, Richard N Sandford, Maryrose Tarpey, Hannah R Bridges, Wendy D Brown, Natasha L O’Brien, Ann C Daly, Bharat K Jindal, Gillian S Mundy, Albert J Power, John Sayer, Roslyn J Simms, Patricia D Wilson

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Outcome of Pleural Empyema Treated With Video-Assisted Thoracoscopic Surgery in Patients With Severe Co-Morbidities: An Observational Study by Vu HA, Nguyen NV, Le TD, Nguyen ST, Viet Le A, The Vu A, Van Nguyen B, Van Nguyen B, Thanh Quan N, An NV, Duc Nghiem T

“…Some comorbidities contained chronic obstructive pulmonary disease (COPD) (25.0%), spontaneous esophageal perforation (16.7%), liver cancer, cirrhosis, esophageal cancer, end-stage renal failure – chronic dialysis (8.7%). The surgery procedures were efficient with a short duration (65.6 ± 9.4 minutes), low incidence of blood transfusion (8.3%), and lower rate of postoperative complications (surgical wound infection 8.3%). …”
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Blood absolute lymphocyte count and trajectory are important in understanding severe COVID-19 by Catharine I. Paules, Jacqueline A. Nordwall, Kathryn Shaw-Saliba, Judith A. Aberg, Edward M. Gardner, Anna L. Goodman, N. Kumarasamy, Shikha Vasudeva, David M. Vock, Crystal M. North, Jens Lundgren, Neil R. Aggarwal, for the STRIVE Network and TICO Trial Study Group

“…Persistent and new lymphopenia were associated with older age, male sex; prior immunosuppression, heart failure, aspirin use, and normal body mass index; biomarkers of organ damage (renal and lung), and ineffective immune response (elevated IL-6 and viral nucleocapsid antigen levels). …”
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El síndrome nefrótico en pediatría: un impacto en la infancia by Aymahara Gómez Morejón, Lidia Pérez González, Ortelio Chaviano Mendoza

“…<strong>Fundamento:</strong> desde el punto de vista clínico, el síndrome nefrótico supone una afección que puede llevar a la insuficiencia renal desde edades tempranas. Es necesario identificar y tratar a tiempo los signos y síntomas de esta enfermedad para poder evitar futuras complicaciones. …”
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First-in-human phase 1 study of the arginase inhibitor INCB001158 alone or combined with pembrolizumab in patients with advanced or metastatic solid tumours by Michael Smith, Aung Naing, Todd Bauer, Kyriakos P Papadopoulos, Osama Rahma, Elena Garralda, Glenn J Hanna, Michael J Pishvaian, Xuejun Chen, Sven Gogov, Omar Saavedra, Howard Kallender, LuLu Cheng, Emil Kuriakose

“…Dose expansion was conducted in tumour-type cohorts (with or without prior anti−PD-1/PD-L1 (programmed death protein 1/programmed death ligand 1) therapy).Results A total of 107 patients received INCB001158 50–150 mg two times per day as monotherapy, and 153 patients, including 6 with moderate renal impairment, received INCB001158 50–100 mg two times per day combined with pembrolizumab. …”
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Lethal necrotizing granulomatous vasculitis after bariatric surgery and bilateral mammaplasty by O. V. Blagova, D. Kh. Aynetdinova, A. V. Nedostup, N. A. Novikova, Ye. A. Kogan, Yu. V. Lerner, L. V. Kozlovskaya, V. V. Rameyev, N. A. Mukhin

“…The patient (32-year-old female) had a history of persistent irregular febrile fever for two years, renal disease (tubulointerstitial nephritis with papillary necrosis), hemorrhagic vasculitis-like skin involvement and mediastinal lymphadenopathy. …”
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In vivo and in silico study of europinidin against streptozotocin-isoproterenol-induced myocardial damage via alteration of hs-CRP/CPK-MB/Caspase-3/Bcl-2 pathways by Khalid Saad Alharbi, Muhammad Afzal, Fahad A. Al-Abbasi, Ehssan Moglad, Salwa D. Al-Qahtani, Naif A. R. Almalki, Faisal Imam, Nadeem Sayyed, Imran Kazmi

“…Europinidin also protected renal, hepatic functions and restored apoptosis markers (increased Bcl-2, decreased caspase-3 levels). …”
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Enhanced renoprotective effects of combined glucagon‐like peptide‐1 receptor agonists and sodium‐glucose cotransporter 2 inhibitors in type 2 diabetes mellitus: Real‐world evidence... by Jian‐Yu Jhu, Yu‐Wei Fang, Chung‐Yen Huang, Hung‐Hsiang Liou, Mon‐Ting Chen, Ming‐Hsien Tsai

“…Conclusions Dual therapy with GLP‐1 RA and SGLT2i is supported to enhance renal outcomes and address the growing burden of diabetic kidney disease.…”
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Hyperspectral imaging in living and deceased donor kidney transplantation by Rasmus Wrigge, Robert Sucher, Fabian Haak, Hans-Jonas Meyer, Julia Unruh, Hans-Michael Hau, Matthias Mehdorn, Hans-Michael Tautenhahn, Daniel Seehofer, Uwe Scheuermann

“…Kidney grafts with low StO2 values (cut-off point 0.6) showed reduced renal function with a low glomerular filtration rate and elevated urea levels in the first two weeks after KT. …”
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Quality of life and overall well-being between healthy individuals and patients with varied clinical diagnoses by Mohamad Adam Bujang, Wei Hong Lai, Xun Ting Tiong, Selvasingam Ratnasingam, Alex Ren Jye Kim, Masliyana Husin, Yvonne Yih Huan Jee, Nurul Fatma Diyana Ahmad, Clare Hui Hong Tan, Khoo Sing Yee, Yoon Khee Hon, Eileen Pin Pin Yap, Fazalena Johari, Alan Yean Yip Fong

“…Among the non-healthy participants, 41 (9.1%) had end-stage renal diseases (ESRD), 48 (10.6%) were diagnosed with cancer, 40 (8.8%) had depressive disorder, and the remaining had heart disease (8.6%). …”
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Depression as a risk factor for osteoporosis independent of sarcopenia in hemodialysis patients: findings from a multicenter cross-sectional study by Xiaohua Hu, Xianwu Ye, Haimin Chen, Bibo Wu, Qi Guo, Chen Yu, Wei Ding, Jianying Niu, Junli Zhao, Hualin Qi, Suhua Zhang, Cheng Xue, Liming Zhang

“…Abstract Background Osteoporosis and sarcopenia frequently occur in patients with end-stage renal disease undergoing hemodialysis (HD), and depression is also a common mental health issue in this population. …”
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Metabolic dysfunction-associated fatty liver disease and risk of nephrolithiasis: a sizeable cross-sectional study by Shengqi Zheng, Tianchi Hua, Guicao Yin, Wei Zhang, Xiaoxiang Wang, Lezhong Qi, Xiayong Jing, Qibing Fan, Xiaoping Yu, Yifan Li

“…Subgroup analyses indicated that, even after accounting for various factors such as age, diabetes, hypertension, obesity, lipid profiles, and renal function, the positive association between MAFLD and an increased risk of nephrolithiasis remained consistent. …”
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Prevalence of communicable, non-communicable diseases, disabilities and related risk factors in Khyber Pakhtunkhwa Pakistan: Findings from the Khyber Pakhtunkhwa Integrated Populat... by Ziaul Haq, Saima Afaq, Muhammad Ibrahim, Zala, Muhammad Asim

“…<h4>Objectives</h4>The objective of this study was to present the demographic characteristics and the burden of locally-specific CDs (hepatitis B and C, TB, AIDS), NCDs (diabetes, renal diseases, asthma, epilepsy, coronary heart diseases, cancer, hypertension, cholesterol, thalassemia), and disabilities (congenital, post-disease, post-injury, paralysis) stratified by sex, age and setting in the Khyber Pakhtunkhwa province of Pakistan.…”
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Unlocking the Potential of Receptor-Based Approaches in Diabetes Treatment by Mohsina Patwekar, Faheem Patwekar, J. Pavan Kumar, P. Dharani Prasad, Nazia Malik, A. Venkata Badarinath, Prashanth Parupathi, Konatham Teja Kumar Reddy, Selvaraja Elumalai, Zainul Abedeen Ab Samad

“…Empagliflozin is a sodium-glucose co-transporter 2 (SGLT2) inhibitor with substantial promise in decreasing blood glucose levels, and providing cardiovascular and renal advantages. Pegbelfermin (BMS-986036), a fibroblast growth factor 21 (FGF21) analogue, is being investigated for its ability to regulate glucose and lipid metabolism, and potentially enhance glycemic control and lipid profiles. …”
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