Pyruvate-Enriched Oral Rehydration Solution Improves Glucometabolic Disorders in the Kidneys of Diabetic db/db Mice by Xiao Meng Zhang, Hao Deng, Jin Dong Tong, Yi Zhen Wang, Xu Chao Ning, Xiu Hong Yang, Fang Qiang Zhou, Hui Min Jin

“…Both Pyr-ORS and 1% pyruvate showed comparable therapeutic effectiveness with controls of body weight and blood sugar, increases of blood insulin levels, and improvement of renal function and pathological changes. Aberrant key enzyme activities in glucometabolic pathways, AR, PK, and PDK/PDH, were also restored; indexes of oxidative stress and inflammation, NAD+/NADH ratio, and AGEs in the kidneys were mostly significantly preserved after pyruvate treatments. …”
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The Emerging Role of Implementing Machine Learning in Food Recommendation for Chronic Kidney Diseases Using Correlation Analysis by Sachin Gupta, Neeraj Garg, Divyanshu Sinha, Babita Yadav, Bhoomi Gupta, Shahajan Miah

“…A correlation analysis has been done in this research to observe the strength of ML using the effective finding for renal malfunctioning and identifying the best food products that could help in its treatment and recovery. …”
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A Study of Hypothyroidism in Chronic Kidney Disease (CKD) Patients by Sudharsanan V, Prabhu Shankar S, Viknesh V

“…Detailed clinical assessments and laboratory analyses of renal and thyroid functions were performed. Results: The study population had a mean age of 50.6 years, with 61.2% females. …”
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Targeting endoplasmic reticulum stress: an innovative therapeutic strategy for podocyte-related kidney diseases by Jiao Lv, Honghai Yu, Sasa Du, Pengyu Xu, Yunyun Zhao, Wenxiu Qi, Xiuge Wang

“…Previous studies have shown that ERS in podocytes can contribute to the development of diseases such as glomerulonephritis, hereditary nephropathy, and diabetic kidney disease, potentially progressing to end-stage renal disease and causing patient mortality. As such, investigating ERS in podocytes has become a key area of focus in kidney disease research. …”
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Sodium glucose co-transporter 2 inhibitors (SGLT2i) for pediatric kidney disease: the future is near by Gilda M. Portalatin, Irene Hong-McAtee, Irene Hong-McAtee, Anna M. Burgner, Edward R. Gould, Tracy E. Hunley, Tracy E. Hunley

“…SGLT2 inhibitors have been developed to promote renal glucose excretion to improve glycemic control in diabetes. …”
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Case Report: Rare cardiovascular characteristics of tuberous sclerosis complex with novel TSC2 variant by Zhiqin Du, Xiao Ma, Xiao Ma, Xiao Ma, Jianhua Li, Fang Yang, Yangfan Guo, Yangfan Guo

“…While cardiovascular involvement is less common than neurological or renal manifestations, it typically presents with cardiac rhabdomyomas (CRs). …”
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Clinical Scenarios for Discordant Anti-Xa by Jesus Vera-Aguilera, Hindi Yousef, Diego Beltran-Melgarejo, Teng Hugh Teng, Ramos Jan, Mary Mok, Carlos Vera-Aguilera, Eduardo Moreno-Aguilera

“…Anti-Xa test is widely used; however the assay underestimates heparin concentration in the presence of significant AT deficiency, pregnancy, end stage renal disease, and postthrombolysis and in patients with hyperbilirubinemia; limited published data evaluating the safety and effectiveness of anti-Xa assays for managing UH therapy is available. …”
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Lymphocytes as an Indicator for Initial Kidney Function: A Single Center Analysis of Outcome after Alemtuzumab or Basiliximab Induction by Annemarie Weissenbacher, Theresa Hautz, Michael Kimelman, Rupert Oberhuber, Hanno Ulmer, Claudia Bösmüller, Manuel Maglione, Stefan Schneeberger

“…Alemtuzumab, an anti-CD52 T-cell and B-cell depleting monoclonal antibody, is established for induction therapy in renal transplantation (KTx). We herein provide a comparative analysis between alemtuzumab and basiliximab induction therapy and correlate lymphocyte depletion and recovery with the clinical course after KTx. …”
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Is There a Role for Daratumumab Retreatment in Patients with Relapsed/Refractory Multiple Myeloma? by Davor Galusic, Ivan Krecak, Viktor Blaslov, Andela Krstulovic Opara, Toni Valkovic, Sandra Basic Kinda

“…Multiple myeloma (MM) is a hematologic disease characterized by the clonal expansion of malignant plasma cells that accumulate in the bone marrow, leading to osteolytic bone disease, hypercalcemia, anemia, and renal dysfunction. Daratumumab was the first monoclonal anti-CD38 antibody approved for the treatment of MM, initially in relapse/refractory settings and, more recently, for newly diagnosed patients. …”
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Multiorgan Failure and Refractory Lactic Acidosis due to Pasteurella multocida Septicemia in a Patient with No Animal Exposure by Damaris Pena, Yaneidy Santana, Jose Perez Lara, Efrain Gonzalez, Misbahuddin Khaja

“…He had severe respiratory distress requiring ventilator support, profound septic shock requiring multiple vasopressors, severe lactic acidosis, and renal failure requiring emergent hemodialysis. Blood cultures confirmed the presence of P. multocida. …”
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Successful Antiviral Treatment with Direct-Acting Antivirals for Hepatitis C Virus Infection during Peritransplant Period in a Kidney Transplant Recipient by Giovanni Varotti, Ferdinando Dodi, Ernesto Paoletti, Andrea Bruno, Iris Fontana

“…On postoperative day 15, the patient was discharged and remains in healthy condition with normal renal function and HCV negative after 18 months of follow-up. …”
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Survival of radioiodine treated hyperthyroid cats that are euthyroid and hypothyroid after treatment, and effect of levothyroxine supplementation on survival time of cats with iatr... by Sarah E. Cox, Jennifer Wakeling, Teresa Hall, Tim L. Williams

“…The log rank test was used to compare survival times between groups, and the Mann‐Whitney U test was used to compare age and renal variables. Data are presented as median [range]. …”
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Neutrophil gelatinase-associated lipocalin: a biochemical marker for acute kidney injury and long-term outcomes in patients presenting to the emergency department by Kah Hui Brian Teo, Swee Han Lim, Ying Hao, Yin Keong Daryl Lo, Ziwei Lin, Manish Kaushik, Chieh Suai Tan, Mohammed Zuhary Thajudeen, Choon Peng Jeremy Wee

“…Our study examined the utility of neutrophil gelatinase-associated lipocalin (NGAL) in predicting AKI in patients presenting to the emergency department (ED), and in predicting the need for renal replacement therapy (RRT), occurrence of major adverse cardiac events (MACE) and all-cause mortality at three months post visit. …”
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Inflammation-Related Mechanisms in Chronic Kidney Disease Prediction, Progression, and Outcome by Simona Mihai, Elena Codrici, Ionela Daniela Popescu, Ana-Maria Enciu, Lucian Albulescu, Laura Georgiana Necula, Cristina Mambet, Gabriela Anton, Cristiana Tanase

“…This review aims to summarize the recent knowledge regarding the relationship between inflammation and CKD, highlighting the current proteomic approaches, as well as the inflammasomes and gut microbiota dysbiosis involvement in the setting of CKD, culminating with the troubling bidirectional connection between CKD and renal malignancy, raised on the background of an inflammatory condition.…”
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Risk of second primary malignancies among survivors of cutaneous melanoma: A nationwide population-based study in the Republic of Korea by Joon Min Jung, Do Hyung Kim, Ye-Jee Kim, Ik Jun Moon, Woo Jin Lee, Sung Eun Chang, Mi Woo Lee, Chong Hyun Won

“…Additionally, specific SPMs were more common among melanoma survivors, including nonmelanoma skin cancer, oral cavity and pharyngeal cancer, renal cancer, female breast cancer, lung cancer, pancreatic cancer, and liver cancer. …”
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Novel yeast Pichia kudriavzevii alleviates aflatoxins induced toxicopathology in broiler chickens through immunomodulation and antioxidant enhancement by Ashiq Ali, Aisha Khatoon, Muhammad Kashif Saleemi, Rao Zahid Abbas, Bilal Murtaza, Kaynaat Akbar, Qaisar Tanveer, Sami Ullah Khan Bahadur, Hissah Abdulrahman Alodaini, Mai Ahmad Alghamdi

“…Assessment encompassed a comprehensive array of parameters including performance metrics, hepatic and renal biomarkers, interleukin concentrations, blood cell counts, hemoglobin concentration, packed cell volume, antibody response to sheep red blood cells, lymphoproliferative response to PHA-P, phagocytic response utilizing the carbon clearance assay system, as well as evaluation of oxidants and antioxidants. …”
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Ruellia tuberosa L. Extract Improves Histopathology and Lowers Malondialdehyde Levels and TNF Alpha Expression in the Kidney of Streptozotocin-Induced Diabetic Rats by Anna Roosdiana, Fajar Shodiq Permata, Riera Indah Fitriani, Khairul Umam, Anna Safitri

“…The treatments induced repairment in the glomerular and renal tubular damages in the kidney tissues. To conclude, these results emphasize potentially health valuable properties of hydroethanolic root extracts of R. tuberosa L. in rats with streptozotocin-induced diabetes.…”
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New Bipolar Electrosurgical Vessel Sealing Device Provides Improved Performance and Procedural Efficiency by Chambers R, Sarno D, Roweton S

“…Rheagan Chambers, Danielle Sarno, Susan Roweton Surgical Research and Development, Surgical Operating Unit, Medtronic, Lafayette, CO, USACorrespondence: Susan Roweton, Email susan.roweton@medtronic.comPurpose: This study compared the performance of the new LigaSure™ XP Maryland Jaw Sealer/Divider (XP Maryland) to that of LigaSure Atlas™ (Atlas) and LigaSure™ Dolphin Tip (Dolphin Tip), two early LigaSure™ (LigaSure) devices characterized by consistent and reliable clinical performance.Methods: Ex vivo bench testing on porcine renal arteries compared burst pressures, seal times, and rates of sticking, incomplete cuts, and charring between XP Maryland and Atlas and between XP Maryland and Dolphin Tip. …”
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N-3 Polyunsaturated Fatty Acids Stimulate Bile Acid Detoxification in Human Cell Models by Anna Cieślak, Jocelyn Trottier, Mélanie Verreault, Piotr Milkiewicz, Marie-Claude Vohl, Olivier Barbier

“…The effects of EPA and/or DHA on the expression of genes involved in the maintenance of BA homeostasis were analyzed in human hepatoma (HepG2) and colon carcinoma (Caco-2) cells, as well as in primary culture of human intestinal (InEpC) and renal (RPTEC) cells. Extracellular BA species were quantified in culture media using LC-MS/MS. …”
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Systemic Factors Associated with Treatment Response in Diabetic Macular Edema by Wendy Meihua Wong, Caroline Chee, Mayuri Bhargava, Charmaine Chai, Hazel Lin, Paul Zhao, Erlangga Ariadarma Mangunkusumo, Thet Naing, Yew Sen Yuen, Tien Yin Wong, Xinyi Su, Gopal Lingam

“…At baseline, information on various systemic factors was collected including glycosylated hemoglobin (HbA1c), serum VEGF levels, lipid profile and markers of renal function, and blood pressure. Thirty-three of the 35 patients were included in this study. …”
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