Nebivolol Ameliorates Nitric Oxide–Deficient Hypertension by L.A. Fortepiani, M.C. Ortiz, N.M. Atucha, Joaquin Garcia-Estan

“…Nebivolol (1 mg/kg/day, 14 days) was given concurrently with the NO synthesis inhibitor Nw-nitro-L-arginine methyl ester (L-NAME, 0.1, 1, and 10 mg/kg/day, 14 days) to several groups of rats. Blood pressure, renal function, plasma renin activity (PRA), and NO activity and metabolites were measured at the end of the treatment period. …”
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Possible erythropoietin pharmacotherapeutic targets on painful diabetic neuropathy in rats by SAMUEL SUAREZ-MENDEZ, DEYSI Y. BERMÚDEZ-OCAÑA

“…Abstract Erythropoietin is a renal cytokine involved in regulating hematopoiesis. …”
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The tyrosine kinase inhibitor lenvatinib is oxidized by rat cytochromes P450 and affects their expression in rat liver by Indra Radek, Jelínková Sandra, Kollárová Katarína, Zahumenská Petra, Dvořák Josef, Dušková Šárka, Dračínská Helena

“…Lenvatinib is an orally effective tyrosine kinase inhibitor used to treat several types of tumors, including progressive, radioiodine-refractory differentiated thyroid cancer and advanced renal cell carcinoma. Although this drug is increasingly used in therapy, its metabolism and effects on the organism are still not described in detail. …”
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Prevalence and co-prevalence of comorbidities among patients with type 2 diabetes mellitus living in Puerto Rico by Enid J García-Rivera, Krystel Ruiz-Serrano, Edgar I Miranda, Luis C Mejía, Adolfo Pinzón, Cecile Marqués-Goyco, José G Quijada, Homero Monsanto, Juan C Orengo

“…The most prevalent comorbidities were hypertension (48%), hyperlipidemia (41%), neuropathy (21%); renal disease (15%), and retinopathy (13%). A high prevalence and co-prevalence of comorbidities and use of healthcare services were identified in patients with T2DM, especially in older adults. …”
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Unveiling the Hidden Burden: Estimating All-Cause Mortality Risk in Older Individuals with Type 2 Diabetes by Dikang Pan, Hui Wang, Sensen Wu, Jingyu Wang, Yachan Ning, Jianming Guo, Cong Wang, Yongquan Gu

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LMW Heparin Prevents Increased Kidney Expression of Proinflammatory Mediators in (NZBxNZW)F1 Mice by Annica Hedberg, Premasany Kanapathippillai, Ole Petter Rekvig, Kristin Andreassen Fenton

“…In this study we investigated the effect of LMW heparin on renal cytokine and chemokine expression and on nucleosome-mediated activation of nucleosome-specific splenocytes. …”
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Ankrd1 as a potential biomarker for the transition from acute kidney injury to chronic kidney disease by Hailin Li, Lemei Hu, Changqing Zheng, Ying Kong, Ming Liang, Quhuan Li

“…Abstract Ischemia-reperfusion injury (IRI) is one of the leading causes of acute kidney injury (AKI), predisposing patients to chronic kidney disease (CKD) due to maladaptive renal repair. Nevertheless, the molecular mechanisms and biomarkers that cause maladaptive repair remain unclear. …”
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Spontaneous Coronary Artery Dissection: A Rare Manifestation of Alport Syndrome by Amornpol Anuwatworn, Prince Sethi, Kelly Steffen, Orvar Jonsson, Marian Petrasko

“…AS has been associated with renal, auditory, and ocular diseases due to the presence of abnormal alpha chains of type IV collagen in the glomerulus, cochlea, cornea, lens, and retina. …”
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A Rare Cause of Persistent Blood Loss after Continuous Ambulatory Peritoneal Dialysis Catheter Placement by T. Natroshvili, T. Elling, S. A. Dam, M. vd Berg, R. R. H. Nap, R. J. Hissink

“…The laparoscopic placement of a continuous ambulatory peritoneal dialysis (CAPD) catheter is a widely used method in patients with end stage renal disease (ESRD). The potential complications of this procedure include perforation of intra-abdominal organs, surgical site infection, peritonitis, catheter migration, catheter blockage, port site herniation, and bleeding. …”
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Kidney stone characteristics in diabetics versus nondiabetics at a tertiary care center in Saudi Arabia by Ibrahim Basem Nafadi, Abdullah Ahmed Alsulami, Nawaf Faisal Halabi, Abdulrahman Abdullah Alsubhi, Sami Wessam Maghrabi, Waleed Saad Alshehri, Majed Ramadan, Anwar Khan, Suhaib Radi

“…In addition, these individuals frequently exhibit other comorbid conditions, including hypertension, dyslipidemia, obesity, and renal disease. The significance of these findings may inform future strategies for both primary and secondary prevention of kidney stones in diabetic patients.…”
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Elevated plasma levels of endothelin are associated with the severity of sepsis and presence of shock in contrast to the levels of atrial natriuretic peptide by A. Beishuizen, J. M. Götz, L. Kip, C. Haanen, I. Vermes

“…Furthermore, ETi correlated well with plasma lactate (r = 0.83, p < 0.05), but not with renal function. ANPi levels did not show correlation with any of these determinants. …”
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Knee pain in adults from the northeast of São Paulo, Brazil: prevalence, risk factors, and impact on quality of life by Alberto de Vitta, Nicoly Machado Maciel, Sandra Fiorelli Almeida Penteado Simeão, Matias Noll

“…Results: The prevalence of knee pain was 25.6% (95% confidence interval: 22.3–29.3%), and it was associated with being >60 years old, black ethnicity, mean or low income, overweight, depression, gastrointestinal and renal diseases, and persons who performed occupations requiring repetitive movements, sitting while using a computer, and standing. …”
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Management of a Novel Autoimmune Disease, COPA Syndrome, in Pregnancy by Archana Ayyar, Rachel D. Seaman, Kalpalatha Guntupalli, Mary C. Tolcher

“…This disease manifests in childhood as pulmonary hemorrhage, arthritis, and renal disease. Case. We present a case of obstetric management of a 20-year-old nulligravida patient with a diagnosis of COPA syndrome. …”
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Severe Metabolic Acidosis: A Case of Triple Hit with Ketogenic Diet, Vinegar, and Metformin in an Obese Patient by Abdul Mughees Rana, Kannan Mansoor, Salman Assad, Mahmoud Abouzid, Iheanyichukwu Ogu, Ghassan Salim Issa Bandak

“…The use of dietary acetic acid is usually well tolerated; however, in this case, the large quantities and presence of acute renal injury and metformin use may have worsened the acidosis. …”
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Successfully Treated Calcific Uremic Arteriolopathy: Two Cases of a High Anion Gap Metabolic Acidosis with Intravenous Sodium Thiosulfate by Joshua L. Rein, Kana N. Miyata, Kobena A. Dadzie, Steven J. Gruber, Roxana Sulica, James F. Winchester

“…Calcific uremic arteriolopathy (CUA) is a rare and potentially fatal disorder of calcification involving subcutaneous small vessels and fat in patients with renal insufficiency. We describe the successful use of intravenous sodium thiosulfate (STS) for the treatment of CUA in two patients. …”
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Pengaruh Intradialytic Range of Motion (ROM) Exercise terhadap Depresi, Insomnia dan Asupan Nutrisi pada Pasien Hemodialisis by Erni Forwaty, Hema Malini, Elvi Oktarina

“…Pada pasien End Stage Renal Disesase (ESRD), meskipun mereka sudah menjalani hemodialisis rutin, namun pasien masih mengalami masalah pada fungsi fisik, psikososial dan kualitas hidup. …”
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Appropriate Use of Inpatient Erythropoiesis Stimulating Agents by Chenghao Cui, Timothy Nguyen, Mohammad Rattu

“…One dose was dispensed when the Hb was 11.1 g/dL to a patient on renal replacement therapy, and one dose was dispensed when the Hb was 13.8 g/dL to a surgical patient who refused blood transfusions. …”
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Chronic kidney disease among people living with HIV on TDF based regimen: A systematic review and meta-analysis. by Taklo Simeneh Yazie, Wondimeneh Shibabaw Shiferaw, Asaye Alamneh Gebeyehu, Assefa Agegnehu Teshome, Zenaw Debasu Addisu, Abebe Muche Belete

“…Early identification of CKD by considering regular renal function monitoring, and risk factors especially low CD4 count, and female gender at birth are essential.…”
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In-Hospital Mortality among Ischemic Stroke Patients in Gondar University Hospital: A Retrospective Cohort Study by Eyob Alemayehu Gebreyohannes, Akshaya Srikanth Bhagavathula, Tamrat Befekadu Abebe, Mohammed Assen Seid, Kaleab Taye Haile

“…Cox regression revealed that only a decrease in renal function, particularly elevated serum creatinine (AHR=8.848, 95% CI: 1.616-67.437), was associated with a statistically significant increase of in-hospital mortality. …”
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Systematic Characterization of Splicing Dysregulation in Pan Solid Tumor Transcriptome by Jingru Sui, Dan Guo, Xiao Wen, Lei Zhou, Yue Huang, Haoyu Yu, Jinyu Chen, Zhaoqi Liu

“…Cross‐cancer commonalities of splicing dysregulation are observed among digestive system neoplasms, renal‐associated tumors, and urogenital tumors. By contrast, brain tumors demonstrate a distinct splicing pattern with the highest ASE‐SF correlation. …”
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