The cryptic lncRNA-encoded microprotein TPM3P9 drives oncogenic RNA splicing and tumorigenesis by Kun Meng, Yuying Li, Xiaoyi Yuan, Hui-Min Shen, Li-Ling Hu, Danya Liu, Fujin Shi, Dandan Zheng, Xinyu Shi, Nengqiao Wen, Yun Cao, Yun-Long Pan, Qing-Yu He, Chris Zhiyi Zhang

“…Here, we show that the novel protein TPM3P9, encoded by the lncRNA tropomyosin 3 pseudogene 9, exhibits oncogenic activity in clear cell renal cell carcinoma (ccRCC) by enhancing oncogenic RNA splicing. …”
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Immunosuppressive therapy and nutritional diseases of patients after kidney transplantation: a systematic review by Aleksandra Anna Kajdas, Marcin Kleibert, Anne Katrine Normann, Krzysztof Krasuski, Ditte Søndergaard Linde, Dorota Szostak-Węgierek

“…Despite kTx being the most effective treatment for end-stage renal disease, the patients face significant morbidity. …”
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Urinary Proteome and Exosome Analysis Protocol for the Discovery of Respiratory Diseases Biomarkers by Laura Martelo-Vidal, Sara Vázquez-Mera, Pablo Miguéns-Suárez, Susana Belén Bravo-López, Heidi Makrinioti, Vicente Domínguez-Arca, Javier de-Miguel-Díez, Alberto Gómez-Carballa, Antonio Salas, Francisco Javier González-Barcala, Francisco Javier Salgado, Juan José Nieto-Fontarigo

“…Therefore, this protocol combining the urinary proteome (exosome free) with the study of urinary exosome components (i.e., miRNAs) holds great potential for molecular biomarker discovery of non-renal and particularly respiratory pathologies.…”
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Collecting duct NCOR1 controls blood pressure by regulating mineralocorticoid receptor by Ke Sun, Yong-Li Wang, Chen-Chen Hou, Da Shang, Lin-Juan Du, Lan Bai, Xing-Yu Zhang, Chuan-Ming Hao, Sheng-Zhong Duan

“…Methods and Results: Collecting duct NCOR1 knockout (KO) mice manifested increased BP and aggravated vascular and renal injury in an angiotensin II (Ang II)-induced hypertensive model. …”
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Calciphylaxis: Temporal Artery Calcification Preceding Widespread Skin Lesions and Penile Necrosis by Manzoor A. Shah, Michael W. Roppolo

“…We report a case of 72-year-old Caucasian man with multiple comorbidities and end-stage renal disease on dialysis who presented with temporal artery calcification leading to bilateral loss of vision followed by extensive skin lesions including one on glans penis. …”
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Caffeic Acid Phenethyl Ester as a Protective Agent against Nephrotoxicity and/or Oxidative Kidney Damage: A Detailed Systematic Review by Sumeyya Akyol, Veli Ugurcu, Aynur Altuntas, Rukiye Hasgul, Ozlem Cakmak, Omer Akyol

“…In this review, we summarized and critically evaluated the current knowledge regarding the protective effect of CAPE in nephrotoxicity induced by several special medicines such as cisplatin, doxorubicin, cyclosporine, gentamycin, methotrexate, and other causes leading to oxidative renal injury, namely, I/R models and senility.…”
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Obesity as a Major Risk Factor for Cancer by Giovanni De Pergola, Franco Silvestris

“…Reports from the International Agency for Research into Cancer and the World Cancer Research Fund (WCRF) have shown that the strongest evidence exists for an association of obesity with the following cancer types: endometrial, esophageal adenocarcinoma, colorectal, postmenopausal breast, prostate, and renal, whereas the less common malignancies are leukemia, non-Hodgkin’s lymphoma, multiple myeloma, malignant melanoma, and thyroid tumours. …”
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Novel Mutations in the MKKS, BBS7, and ALMS1 Genes in Iranian Children with Clinically Suspected Bardet–Biedl Syndrome by Roghayeh Dehghan, Mahdiyeh Behnam, Mansoor Salehi, Roya Kelishadi

“…Bardet–Biedl syndrome is a rare autosomal recessive form of syndromic obesity which is characterized by retinal degeneration, obesity, polydactyly, cognitive impairment, and renal and urogenital anomalies. In this study, we used whole-exome sequencing (WES) to investigate the underlying mutations in four Iranian children from consanguineous families with a clinical diagnosis of Bardet–Biedl syndrome (BBS). …”
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A new method for measuring dopamine in the presence of uric acid employing a carbon paste electrode modified with the UiO-66 metal organic framework-graphene oxide nanocomposite by Azhar Hameed Gatea, Aseer Shakir Ajel, Raed Muslim Muhibes

“… Background and purpose: Dopamine has an impact on the cardiovascular, endocrine, renal, and central neurological systems. Electrochemical techniques are becoming more and more popular among researchers as a way to assess dopamine and uric acid levels. …”
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A mouse model of Bardet-Biedl Syndrome has impaired fear memory, which is rescued by lithium treatment. by Thomas K Pak, Calvin S Carter, Qihong Zhang, Sunny C Huang, Charles Searby, Ying Hsu, Rebecca J Taugher, Tim Vogel, Christopher C Cychosz, Rachel Genova, Nina N Moreira, Hanna Stevens, John A Wemmie, Andrew A Pieper, Kai Wang, Kai Wang, Val C Sheffield

“…Primary cilia are microtubule-based organelles present on most cells that regulate many physiological processes, ranging from maintaining energy homeostasis to renal function. However, the role of these structures in the regulation of behavior remains unknown. …”
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Risk factors for multiple organic dysfunctions syndrome in burnt children. by Elvira Maria Martinez Barreto, Jorge González Mendoza

“…The considered systems for dysfunction diagnosis were: respiratory, cardiovascular, gastrointestinal, hepatic, renal, metabolic, central nervous system, hematologic, immunologic, and wounds healing. …”
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Role of Endothelial Nitric Oxide Synthase in Diabetic Nephropathy: Lessons from Diabetic eNOS Knockout Mice by Takamune Takahashi, Raymond C. Harris

“…Diabetic nephropathy (DN) is the leading cause of end-stage renal disease in many countries. The animal models that recapitulate human DN undoubtedly facilitate our understanding of this disease and promote the development of new diagnostic markers and therapeutic interventions. …”
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Case of Cardiac Arrest Treated with Extra-Corporeal Life Support after MDMA Intoxication by Pierre Voizeux, Romain Lewandowski, Theresa Daily, Omar Ellouze, Olivier Bouchot, Belaïd Bouhemad, Pierre-Grégoire Guinot

“…Later, he also benefited from renal replacement therapy and mechanical ventilation. …”
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Tocilizumab Use in a Chronic Hemodialysis Patient for the Management of COVID-19-Associated Pneumonia and Acute Respiratory Distress Syndrome by Sudeendra Gupta, Rakesh Madhyastha, Fadi Hamed, Maher Balkis, Wasim El Nekidy, Nizar Attallah

“…In this article, we address a particularly more susceptible group of the population of end-stage renal disease (ESRD) patients on dialysis who may potentially benefit from being treated with tocilizumab. …”
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Antenatal Bartter Syndrome: A Review by Y. Ramesh Bhat, G. Vinayaka, K. Sreelakshmi

“…Antenatal Bartter syndrome (ABS) is a rare autosomal recessive renal tubular disorder. The defective chloride transport in the loop of Henle leads to fetal polyuria resulting in severe hydramnios and premature delivery. …”
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Role of Multislice Computed Tomography and Local Contrast in the Diagnosis and Characterization of Choanal Atresia by Khaled Al-Noury, Alsaid Lotfy

“…One of these patients had several congenital abnormalities, including cardiac and renal deformities and a hypoplastic lateral semicircular canal. …”
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VEGF Spliced Variants: Possible Role of Anti-Angiogenesis Therapy by Caroline Hilmi, Mélanie Guyot, Gilles Pagès

“…Among these tumour types, clear cell renal cell carcinomas (RCCs) are the most vascularized tumours due to mutations of the von Hippel Lindau gene resulting in HIF-1 alpha stabilisation and overexpression of Vascular Endothelial Growth Factor (VEGF). …”
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Clinicopathological analysis of sclerosing angiomatoid nodular transformation in the spleen by Shufei Wei, Yongliang Han, Yingyong Hou, Liangliang Wang

“…One case was complicated with renal clear cell carcinoma, and one was complicated with hepatocellular carcinoma. …”
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The Association between Gly460Trp-Polymorphism of Alpha-Adducin 1 Gene (ADD1) and Arterial Hypertension Development in Ukrainian Population by Svitlana Yermolenko, Yaroslav Chumachenko, Viktor Orlovskyi, Irina Moiseyenko, Oleksandr Orlovskyi

“…It is suggested that one of the salt-sensitive arterial hypertension potential markers may be the alpha-adducin gene because its protein product is involved in the ion transport regulation in the renal epithelium. Thus, the aim of the study was to investigate the association between ADD1 Gly460Trp-polymorphism and the AH development risk among patients with different risk factors in the Ukrainian population. …”
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Moringa oleifera Supplemented Diets Prevented Nickel-Induced Nephrotoxicity in Wistar Rats by O. S. Adeyemi, T. C. Elebiyo

“…The histopathology revealed damaged renal tubules and glomerular walls caused by NiSO4 exposure. …”
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