The AEDUCATE Collaboration. Comprehensive antenatal education birth preparation programmes to reduce the rates of caesarean section in nulliparous women. Protocol for an individual... by Soo Downe, Lisa Askie, Sarah J Lord, Hannah G Dahlen, Kenneth William Finlayson, Anna Lene Seidler, Federico Girosi, Kylie Elizabeth Hunter, Kate M Levett, Mary-Ann Davey, Caroline A Smith, Julie Fleet, Mary Steen, Elizabeth Newnham, Anette Werner, Leslie Arnott, Kerry Sutcliffe

“…Methods and analysis Population: women with singleton vertex pregnancies, no planned caesarean section (CS) or epidural.Intervention: in addition to hospital-based standard care, a comprehensive antenatal education programme that includes multiple components for birth preparation, addressing the three objectives: preparing women and their birth partner/support person for childbirth through education on physiological/hormonal birth (knowledge and understanding); building women’s confidence through psychological preparation (positive mindset) and support their ability to birth without pain relief using evidence-based tools (tools and techniques). …”
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Efficacy and safety of single and double catheter intrathecal drug delivery systems in patients with refractory neck and abdominal cancer pain by Qin Li, Huaiming Wang, Qiju Li, Maoxia Xu, Bo Zhong, Xin Hu, Jiang Zou, Pengjiu Feng, Aimin Zhang

“…Abstract Intrathecal drug delivery systems (IDDS) is a crucial for treating refractory cancer pain, but their effectiveness in patients with pain across multiple spinal segments is limited by the localized spread of pain relief medication. Our team innovatively implanted double-catheter IDDS to manage pain related to neck and abdominal cancer. …”
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Phase I clinical trial testing the dose escalation and expansion of Pressurized IntraThoracic Hyperthermic Aerosol Cisplatin administration (PITHAC) for the management of pleural c... by Louis-Emmanuel Chriqui, Etienne Abdelnour-Berchtold, Edoardo Zanfrini, Severine Devesa-Perez, Michel Gonzalez, Thorsten Krueger, Kim Ellefsen, Alice Destaillats, David Bonnet, Martin Hübner, Hasna Bouchaab, Michal Bassani-Sternberg, Solange Peters, Sabrina Cavin, Jean Y Perentes

“…Its management consists in systemic therapies combined to dyspnea relief procedures. Prior studies have tested hyperthermic intrathoracic chemotherapy to treat pleural carcinosis with interesting patient survival results. …”
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Cannabidiol Alleviates Chronic Prostatitis and Chronic Pelvic Pain Syndrome via CB2 Receptor Activation and TRPV1 Desensitization by Jun Jie Piao, Soomin Kim, Dongho Shin, Hwa Jong Lee, Kyung-Hwa Jeon, Wen Jie Tian, Kyung Jae Hur, Jong Soo Kang, Hyun-Je Park, Joo Young Cha, Aeri Song, Sang-Hyuck Park, Mahadevan Rajasekaran, Woong Jin Bae, Sungjoo Kim Yoon, Sae Woong Kim

“…Conclusions: CBD inhibits the TLR4/NF-κB pathway by activating the CB2 receptor, desensitizes the TRPV1 receptor, and decreases the release of COX2. This results in relief of inflammation and pain in patients with CP/CPPS, indicating CBD as a potential treatment for CP/CPPS.…”

Application of high-quality nursing for COVID-19 patients in makeshift hospitals (优质护理在方舱医院内新型冠状病毒肺炎患者中的应用) by YAN Haichun (闫海春), MI Yuehua (米跃华), ZHAO Chunhua (赵春华), SUN Hongyan (孙红艳), YOU Xin (尤欣), LI Liyuan (李莉媛), ZHANG Xiaoyun (张潇允), MA Lixin (马立新), ZHANG Kungang (张坤岗), JIA Qiong (贾琼), XIAO Jiale (肖嘉乐), HAN Miaomiao (韩苗苗), LIU Siyu (刘思雨), WANG Kaiyan (万开颜)

“…Conclusion High-quality nursing plays an important role in relief of negative emotion, prevention of cross-infection and promotion of rehabilitation among COVID-19 patients in makeshift hospitals. …”
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improving Pain mAnagement for childreN and young people attendeD by Ambulance (PANDA): protocol for a realist review. [version 3; peer review: 2 approved, 1 approved with reservati... by Paul Leighton, Georgette Eaton, Georgie Nicholls, Kacper Sumera, Marishona Ortega, Jessica Hodgson, Michael Baliousis, Aloysius Niroshan Siriwardena, Despina Laparidou, Bill Lord, Sarah Redsell, Gregory Adam Whitley, Tatiana Bujor

“…Studies have shown that prehospital pain management in CYP is poor, with 61% of those suffering acute pain not achieving effective pain relief (abolition or reduction of pain score by 2 or more out of 10) when attended by ambulance. …”
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Evaluation of Prayer Windows with Inscriptions Located Around the Mausoleum of Eyup Sultan by Saliha Tanık, Aliye Öten

“…The stumpage technique was applied to the inscriptions and high-relief decorations. There were some difficulties in measuring and photographing the windows due to the location of the land and the passage point of the people. …”
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Optimization of Key Parameters for Coal Seam L-CO₂ Phase Transition Blasting Based on Response Surface Methodology by Xuanping Gong, Xiaoyu Cheng, Cheng Cheng, Quangui Li, Jizhao Xu, Yu Wang

“…Liquid carbon dioxide (L-CO₂) phase transition blasting technology, known for its high efficiency, environmental friendliness, and controllable energy output, has been widely applied in mine safety fields such as coal roadway pressure relief and coal seam permeability enhancement. However, the synergistic control mechanism between L-CO₂ blasting loads and in situ stress conditions on coal seam fracturing and permeability enhancement remains unclear. …”
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Fracture-seepage characteristic zones of the overburden of extra-thick coal seams: Evolutionary patterns and their engineering applications by Xiangguo KONG, Tianshuo ZHAO, Haifei LIN, Pengxiang ZHAO, Xu WANG, Yuchu CAI, Pengfei JI, Di HE, Ke LI, Chuanyu XU

“…Objective and Methods Given that the overburden’s structure significantly influences pressure relief gas extraction, this study aims to explore the gas migration patterns of the overburden of thick coal seams during coal seam mining. …”
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Clinical Guidelines of the Russian Society of Surgeons, the Russian Gastroenterological Association, the Association of Surgeons-Hepatologists and the Endoscopic Society “REndO” o... by V. T. Ivashkin, A. G. Kriger, A. V. Okhlobystin, M. A. Anischenko, S. S. Kardasheva, S. A. Alekseenko, S. F. Bagnenko, M. I. Bykov, S. A. Budzinskiy, I.  M. Buriev, V. A. Vishnevskiy, E. I. Galperin, V. P. Glabay, V. R. Goltsov, T. G. Dyuzheva, G. G. Karmazanovskiy, M. P. Korolev, D. M. Krasilnikov, Yu. A. Kucheryavy, I. V. Maev, N. A. Maystrenko, M. F. Osipenko, M. I. Prudkov, V. I. Simanenkov, E. G. Solonitsin, A. V. Fedorov, E. D. Fedorov, I. B. Khlynov, M. V. Chikunova, A. V. Shabunin, S. G. Shapovalyants, A. A. Sheptulin, O. S. Shifrin

“…Conservative treatment of patients with CP is provided for symptom relief and prevention of complications. Individual cases with severe non-interactable abdominal pain, as well as a complicated course of the disease (development of ductal hypertension due to main pancreatic duct stones or strictures, obstructive jaundice caused by compression of the common bile duct, symptomatic postnecrotic cysts, portal hypertension due to compression of the portal vein or thrombosis of the splenic vein, persistent duodenal obstruction, pseudoaneurysm of the celiac trunk basin and the superior mesenteric artery) serve as an indication for endoscopic or surgical treatment. …”
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Comparative analysis of clinical efficacy of unilateral biportal endoscopic and open transforaminal lumbar interbody fusion in the treatment of lumbar degenerative by Tao Ma, Xiaoshuang Tu, Junyang Li, Yongcun Geng, Yongcun Geng, Jingwei Wu, Senlin Chen, Dengming Yan, Dengming Yan, Ming Jiang, Ming Jiang, Gongming Gao, Luming Nong

“…Patients in the ULIF group experienced quicker relief from back pain postoperatively, but there were no significant differences between the ULIF and TLIF groups in the VAS, ODI, and satisfaction rates at the final follow-up. …”
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Gas drainage and utilization in coal mines in China: History, technological advances, and prospects by Guofu LI, Chao LI, Bichuan ZHANG, Yun XU, Zheng WANG, Xianjun ZHOU

“…From the 1980s to the end of the 20th century, with a substantial increase in the gas outflow from the mining face, pressure-relief gas was effectively drained using various methods including gas pre-drainage in target coal seams, as well as gas pumping in adjacent strata and goaves. …”
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Diagnosis and Treatment of Gastroesophageal Reflux Disease (Clinical Guidelines of the Russian Gastroenterological Association, Russian Scientific Medical Society of Internal Medic... by V. T. Ivashkin, A. S. Trukhmanov, I. V. Maev, O. M. Drapkina, M. A. Livzan, A. I. Martynov, T. L. Lapina, A. V. Paraskevova, D. N. Andreev, O. P. Alexeeva, S. A. Alekseenko, A. Yu. Baranovsky, O. V. Zayratyants, O. Yu. Zolnikova, O. B. Dronova, I. L. Kliaritskaia, N. V. Korochanskaya, Yu. A. Kucheryavyy, S. N. Mammaev, M. F. Osipenko, S. S. Pirogov, E. A. Poluektova, D. E. Rumyantseva, R. G. Sayfutdinov, O. A. Storonova, Yu. P. Uspenskiy, I. B. Khlynov, V. V. Tsukanov, A. A. Sheptulin

“…Combination therapy Rebamipide with PPIs increases the effectiveness of relief of GERD symptoms, as well as reduces the frequency of relapses.Conclusion. …”
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Syzygium aromaticum extract mediated, sustainable silver nanoparticle synergetic with heterocyclic antibiotic clarithromycin and their antimicrobial activities by Zehra Edis, Zehra Edis, Samir Haj Bloukh, Samir Haj Bloukh, Akram A. Ashames, Akram A. Ashames, Moawia M. Al-Tabakha, Moawia M. Al-Tabakha, Moyad J. S. A. Shahwan, Moyad J. S. A. Shahwan, Hamed Abu Sara, Hamed Abu Sara, Sai H. S. Boddu, Sai H. S. Boddu, Sohaib N. Khan, Sohaib N. Khan, Ibrahim Haj Bloukh, Maram Eladdasy, Somayeh Sadeghi, Haneen Alkubaisi, Iman Haj Bloukh, Nageeb A. G. M. Hassan, Nageeb A. G. M. Hassan

“…It has also been used historically for its pain relief especially for tooth ache. Clove extract derived nanoparticle synthesis is a promising method of combining therapeutics with metals at nanoscale. …”
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Les Immatériaux de Lyotard (1985) : un programme figural by Jean-Louis Déotte

“…Une fois posée la question de la destination humaine, dès le vestibule d’entrée, avec un bas-relief égyptien (la déesse offrant le signe de la vie au roi Nectanébo II, un fragment de paroi du temple de Karnak Nord), le spectateur se retrouvait dans le Théâtre du non-corps où s’ouvraient cinq parcours différents organisant tous les sites de l’exposition. …”
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Diagnosis and treatment of the irritable bowel syndrome: clinical guidelines of the Russian gastroenterological association and Russian association of coloproctology by V. T. Ivashkin, Yu. A. Shelygin, Ye. K. Baranskaya, Ye. A. Belousova, A. G. Beniashvili, S. V. Vasilyev, A. O. Golovenko, O. V. Golovenko, Ye. G. Grigoryev, N. V. Kostenko, T. L. Lapina, I. D. Loranskaya, O. S. Lyashenko, I. V. Mayev, Ye. A. Poluektova, V. G. Rumyantsev, V. M. Timerbulatov, A. S. Trukhmanov, O. Yu. Fomenko, I. L. Khalif, E. Yu. Chashkova, A. A. Sheptulin, O. S. Shifrin, V. V. Yanovoy

“….: hyoscine butylbromide, pinaverium bromide, mebeverine) are recommended for abdominal pain relief. For diarrhea-predominant IBS such medications as loperamide hydrochloride, dioctaedric smectite, non-absorbable antibiotic rifaximin and probiotics may be prescribed. …”
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Biosynthesis inhibition of miR-142-5p in a N 6-methyladenosine-dependent manner induces neuropathic pain through CDK5/TRPV1 signaling by Jinshi Li, Yang Guo, Chen Zhu, Dongxu Wang, Yuan Li, Xiaotong Hao, Linyan Cao, Yiting Fan, Bo Fang

“…Knockdown of METTL14 led to decreased pri-miR-124 expression, increased pre-miR-124 expression, and enhanced mature miR-142-5p expression, indicating the relief of miR-142-5p maturation repression. The in vivo results indicated that miR-142-5p negatively regulated the expression of CDK5 and TRPV1, suppressed the expression of inflammatory factors IL-6 and TNF, and improved the PWMT and PWTL. …”
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Clinical observation of external application of compound Baiyu powder in treating cracked nipples during lactation period and related nursing management (复方白玉散外敷治疗哺乳期乳头皲裂临床疗效观察及护理)... by CHEN Shuangshuang (陈双双), WANG Yuan (王媛), YOU Tingli (游婷李), CHEN Juan (陈娟)

“…A shorter time to pain relief and healing of cracked skin were observed in group A than those in group B and control group, respectively(P＜0. 01). …”
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Systematic review and meta-analysis to examine intrapartum interventions, and maternal and neonatal outcomes following immersion in water during labour and waterbirth by Priscilla J Hall, Claire Feeley, Ethel Burns, Jennifer Vanderlaan

“…Objectives Water immersion during labour using a birth pool to achieve relaxation and pain relief during the first and possibly part of the second stage of labour is an increasingly popular care option in several countries. …”
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Identification and susceptibility assessment of landslide disasters in the red bed formation along the Nanjian-Jingdong Expressway by Yifan Cao, Zhifang Zhao, Mingchun Wen, Xin Zhao, Dingyi Zhou, Jingyi Qin, Liu Ouyang, Jingyao Cao

“…The findings from the stacking reveal that high-risk areas comprise 12.29 % of the total area of the research zone, predominantly located along the northern highway, where average annual rainfall and topographic relief are the primary driving factors for landslide occurrences.…”
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